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51. 发明申请

WO9835053A2 ELECTROCHEMICAL ANALYTE SENSORS USING THERMOSTABLE SOYBEAN PEROXIDASE 审中-公开
标题翻译：电化学分析仪使用热稳定的大豆过氧化物
公开(公告)号：WO9835053A2
公开(公告)日：1998-08-13
申请号：PCT/US9802403
申请日：1998-02-11
申请人： HELLER E & CO , HELLER ADAM , KENAUSIS GREGG L , CHEN QIANG , VREEKE MARK S
发明人： HELLER ADAM , KENAUSIS GREGG L , CHEN QIANG , VREEKE MARK S
IPC分类号： C12N15/09 , C12Q1/00 , C12Q1/28 , C12Q1/68 , G01N27/327
CPC分类号： C12Q1/6825 , C12Q1/005 , Y10S435/817
摘要： A sensor for the detection and measurement of an analyte in a biofluid. The sensor includes two enzymes. One type of sensor measures the concentration of hydrogen peroxide using a thermostable peroxidase enzyme that is immobilized in a redox hydrogel to form a sensing layer on a working electrode. This sensor also includes a hydrogen peroxide-generating second enzyme which is insulated from the redox hydrogel and electrode. This second enzyme generates hydrogen peroxide in response to the presence of an analyte or analyte-generated compound. The second enzyme may be insulated from the electrode by placement of an electrically insulating layer between the sensing layer and the second enzyme layer. Alternatively, the second enzyme is immobilized in an inorganic polymeric matrix, preferably made using a sol-gel polymerization process. Such matrices include those made of silica. Often, the second enzyme is stabilized by immobilization in a sol-gel. Further stabilization of polyelectrolytic enzymes can be obtained by immobilizing the enzyme with a polyelectrolytic polymer in the sol-gel matrix.
摘要翻译：用于检测和测量生物流体中分析物的传感器。传感器包括两种酶。一种传感器使用固定在氧化还原水凝胶中的热稳定过氧化物酶测量过氧化氢的浓度，以在工作电极上形成感测层。该传感器还包括与氧化还原水凝胶和电极绝缘的产生过氧化氢的第二酶。该第二酶响应于分析物或分析物产生的化合物的存在而产生过氧化氢。第二酶可以通过在感测层和第二酶层之间放置电绝缘层而与电极绝缘。或者，将第二酶固定在无机聚合物基质中，优选使用溶胶 - 凝胶聚合方法制备。这些基质包括由二氧化硅制成的那些。通常，通过固定在溶胶 - 凝胶中来稳定第二种酶。聚电解酶的进一步稳定可以通过在溶胶 - 凝胶基质中用聚电解质聚合物固定酶来获得。

52. 发明申请

WO1998030024A1 COMPUTER MONITOR HOOD 审中-公开
标题翻译：电脑监视器
公开(公告)号：WO1998030024A1
公开(公告)日：1998-07-09
申请号：PCT/CA1996000882
申请日：1996-12-30
申请人： HELLER, Philip , HELLER, David
IPC分类号： H04N05/65
CPC分类号： H04N5/65 , G06F1/1603 , H01J29/896 , H01J2229/8922
摘要： A computer monitor hood comprises top, left side and right side shading panels each having an outwardly facing surface, a monitor facing surface, front, rear, left and right side edges. A counterweight receiving portion is disposed on the computer monitor and has a first slip-resistant surface. A counterweight having a second slip-resistant surface is selectively manually placeable in any one of a plurality of front-to-rear positions on the counterweight receiving portion, with the first and second slip-resistant surfaces being in cooperating engagement one with the other so as to retain the counterweight in any selected position, thereby balancing the computer monitor hood at a selected position on the computer monitor such that the top, left side, and right side shading panels each project forwardly from the front of the computer monitor, at the respective of the top, left side, and right side surfaces of the computer monitor, so as to shade the screen of the computer monitor. In another embodiment, the top shading panel includes a substantially rigid external layer, and a compliant layer of easily displaceable material disposed on the top shading panel opposite the outwardly facing surface, which compliant layer conforms to the shape of the contacted portion of the monitor, thereby receiving the monitor in seated relation, thus keeping the monitor hood in place. In yet another embodiment, an elastic member or a spring member biases the left and right shading panels into frictional contact with said left and right side surfaces of the monitor.
摘要翻译：计算机监视器罩包括顶部，左侧和右侧遮蔽面板，每个具有向外的表面，面向监视器的表面，前，后，左和右侧边缘。配重接收部分设置在计算机监视器上并且具有第一防滑表面。具有第二防滑表面的配重选择性地可手动放置在配重容纳部分上的多个前后位置中的任一个中，其中第一和第二防滑表面与另一个之间的配合接合以将配重保持在任何选定的位置，从而将计算机监视器罩平衡在计算机监视器上的选定位置，使得顶部，左侧和右侧阴影面板各自从计算机监视器的前部向前突出，分别位于计算机监视器的顶部，左侧和右侧表面，以便遮蔽计算机监视器的屏幕。在另一个实施例中，顶部遮光板包括基本上刚性的外部层，以及易于移位的材料的柔性层，其设置在与面向外的表面相对的顶部遮光板上，该柔顺层与监视器的接触部分的形状一致，从而接收座椅关系的监视器，从而将监视器罩保持在适当的位置。在另一个实施例中，弹性构件或弹簧构件将左右阴影面板偏压到与监视器的左侧面和右侧表面摩擦接触。

53. 发明专利

DD200478A1 未知
公开(公告)号：DD200478A1
公开(公告)日：1983-05-04
申请号：DD23311781
申请日：1981-09-08
申请人： KERSTEN PETER DIPL ING , KERSTEN PETER , MUELLER ERICH , MUELLER ERICH , MEIXNER PETER , MEIXNER PETER , HELLER HELMUT , HELLER HELMUT
发明人： KERSTEN PETER DIPL-ING , KERSTEN PETER , MUELLER ERICH , MUELLER ERICH , MEIXNER PETER , MEIXNER PETER , HELLER HELMUT , HELLER HELMUT
IPC分类号： E02F3/24

54. 发明专利

CA99195A SLICING MACHINE 未知
公开(公告)号：CA99195A
公开(公告)日：1906-05-29
申请号：CA99195D
申请日：1906-05-07
申请人： WOLF SAYER AND HELLER , HELLER ISIDOR
发明人： HELLER ISIDOR

55. 发明专利

RO65545A 未知
公开(公告)号：RO65545A
公开(公告)日：1980-06-15
申请号：RO7828774
申请日：1974-04-03
申请人： HELLER GEB , HELLER UPHUSEN GEB
发明人： KLEINE WERNER K M
IPC分类号： B23B51/00 , B23B31/00 , B23B31/02 , B28D1/14 , E21B10/00 , E21B10/44 , E21B17/04 , B23B51/12

56. 发明专利

FR326119A 未知
公开(公告)号：FR326119A
公开(公告)日：1903-05-16
申请号：FR326119D
申请日：1902-11-05
申请人： HELLER JR LUDWIG , HELLER OTTO
发明人： LUDWIG HELLER JR. , OTTO HELLER
IPC分类号： G09F3/18

57. 发明申请

WO2012079072A2 SUBCUTANEOUSLY INFUSIBLE LEVODOPA PRODRUG COMPOSITIONS AND METHODS OF INFUSION 审中-公开
标题翻译：不孕不育LEVODOPA PRODRUG组合物和输注方法
公开(公告)号：WO2012079072A2
公开(公告)日：2012-06-14
申请号：PCT/US2011064398
申请日：2011-12-12
申请人： SYNAGILE CORP , HELLER ADAM , HELLER EPHRAIM
发明人： HELLER ADAM , HELLER EPHRAIM
IPC分类号： A61K31/198
CPC分类号： A61K31/216 , A61K31/198 , C07C233/46 , C07C233/87 , C07C235/06 , C07C235/74 , C07C237/20
摘要： The invention features methods compositions and infusion pumps for infusing levodopa prodrugs (e.g., levodopa esters, levodopa amides, levodopa carboxamides, and levodopa sulfonamides) for the treatment of Parkinson's disease.
摘要翻译：本发明的特征在于用于输注左旋多巴前药（例如左旋多巴酯，左旋多巴酰胺，左旋多巴甲酰胺和左旋多巴磺酰胺）的方法组合物和输注泵用于治疗帕金森病。

58. 发明申请

WO9967628A9 MULTI-SENSOR ARRAY FOR ELECTROCHEMICAL RECOGNITION OF NUCLEOTIDE SEQUENCES AND METHODS 审中-公开
标题翻译：用于电化学识别核苷酸序列的多传感器阵列和方法
公开(公告)号：WO9967628A9
公开(公告)日：2000-04-06
申请号：PCT/US9914460
申请日：1999-06-24
申请人： HELLER E & CO , LUMLEY WOODYEAR THIERRY DE , CARUANA DAREN J , HELLER ADAM
发明人： DE LUMLEY-WOODYEAR THIERRY , CARUANA DAREN J , HELLER ADAM
IPC分类号： G01N33/53 , B01J19/00 , B01L3/00 , C12M1/00 , C12M1/34 , C12N15/09 , C12Q1/68 , C40B40/06 , C40B60/14 , G01N27/403 , G01N27/416 , G01N33/543 , G01N33/566 , G01N37/00 , G01N27/327 , G01N33/50
CPC分类号： C12Q1/6825 , B01J19/0046 , B01J2219/00286 , B01J2219/00353 , B01J2219/00418 , B01J2219/00497 , B01J2219/00527 , B01J2219/00585 , B01J2219/00596 , B01J2219/00653 , B01J2219/00659 , B01J2219/00677 , B01J2219/00713 , B01J2219/00722 , B01J2219/00729 , B01L3/5027 , C12Q1/6837 , C40B40/06 , C40B60/14 , G01N27/3277 , G01N33/5308 , G01N33/5438 , C12Q2565/501 , C12Q2563/125 , C12Q2537/125 , C12Q2565/607 , C12Q2563/113 , C12Q2527/101
摘要： Sensor and method of its production and use in the electrochemical detection of nucleic acid sequences.
摘要翻译：传感器及其生产方法及其在核酸序列的电化学检测中的应用。

59. 发明专利

AU3137800A Computer monitor hood 未知
公开(公告)号：AU3137800A
公开(公告)日：2000-11-14
申请号：AU3137800
申请日：2000-03-01
申请人： HELLER DAVID , HELLER PHILIP
发明人： HELLER PHILIP , HELLER DAVID
IPC分类号： G06F1/16 , H01J29/89
摘要： A computer monitor hood is provided having top, left side, and right side shading panels. The computer monitor hood is formed as a monolithic structure, and is made of rigid material having elastic memory. When it is first molded, the bottom edges of the left side and right side shading panels are closer together than their top edges so that, when the computer monitor hood is in place on a computer monitor, the left side and right side shading panels are biased into frictional contact with the computer monitor as a consequence of the elastic memory attempting to restore the left side and right side shading panels to their unstressed position. Thus, the computer monitor hood may be placed in any selected position on a computer monitor as a consequence of the left side and right side shading panels being biased towards and in frictional contact with the sides of the computer monitor.

60. 发明专利

CA2275268C COMPUTER MONITOR HOOD 未知
公开(公告)号：CA2275268C
公开(公告)日：2000-10-10
申请号：CA2275268
申请日：1996-12-30
申请人： HELLER DAVID , HELLER PHILIP
发明人： HELLER DAVID , HELLER PHILIP
IPC分类号： G09F9/00 , G06F1/16 , H01J29/89 , H04N5/64 , H04N5/65
摘要： A computer monitor hood comprises top, left side and right side shading panels each having an outwardly facing surface, a monitor facing surface, front, rear, left and right side edges. A counterweight receiving portion is disposed on the computer monitor and has a first slip-resistant surface. A counterweight having a second slip-resistant surface is selectively manually placeable in any one of a plurality of front-to-rear positions on the counterweight receiving portion, with the first and second slip-resistant surfaces being in cooperating engagement one with the other so as to retain the counterweight in any selected position, thereby balancing the computer monitor hood at a selected position on the computer monitor such that the top, left side, and right side shading panels each project forwardly from the front of the computer monitor, at the respective of the top, left side, and right side surfaces of the computer monitor, so as to shade the screen of the computer monitor. In another embodiment, the top shading panel includes a substantially rigid external layer, and a compliant layer of easily displaceable material disposed on the top shading panel opposite the outwardly facing surface, which compliant layer conforms to the shape of the contacted portion of the monitor, thereby receiving the monitor in seated relation, thus keeping the monitor hood in place. In yet another embodiment, an elastic member or a spring member biases the left and right shading panels into frictional contact with said left and right side surfaces of the monitor.

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