专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

41. 发明申请

WO2012174271A3 SYNTHETIC GENE CLUSTERS 审中-公开
标题翻译：合成基因组
公开(公告)号：WO2012174271A3
公开(公告)日：2013-06-13
申请号：PCT/US2012042502
申请日：2012-06-14
申请人： UNIV CALIFORNIA , MIRSKY ETHAN , TEMME KARSTEN , VOIGT CHRIS , ZHAO DEHUA
发明人： MIRSKY ETHAN , TEMME KARSTEN , VOIGT CHRIS , ZHAO DEHUA
IPC分类号： C12N15/09 , C12N15/31 , C12N15/63
CPC分类号： C12N15/635 , C07K14/255 , C07K14/26 , C12N9/0095 , C12N15/52 , C12N15/63 , C12N15/67 , C12N15/74 , C12Y118/06001 , G06F19/20 , G06F19/22
摘要： Methods for making synthetic gene clusters are described.
摘要翻译：描述制备合成基因簇的方法。

42. 发明申请

WO2013070949A1 CONSOLIDATED BIOPROCESS FOR BIOFUEL AND CHEMICAL PRODUCTION FROM LIGNOCELLULOSIC BIOMASS 审中-公开
标题翻译：生物化学和生物化学生物物质的综合生物学
公开(公告)号：WO2013070949A1
公开(公告)日：2013-05-16
申请号：PCT/US2012/064201
申请日：2012-11-08
申请人： THE REGENTS OF THE UNIVERSITY OF CALIFORNIA
发明人： FAN, Zhiliang , SZEWCZYK, Edyta
IPC分类号： C12N15/09 , C12N15/52 , C12N15/56 , C12P7/00 , C12P39/00 , C12N9/38
CPC分类号： C07K14/26 , C12N9/0006 , C12N9/1051 , C12N9/2445 , C12N9/2468 , C12N9/2471 , C12N9/2477 , C12N9/2491 , C12N11/04 , C12N15/52 , C12P7/065 , C12P7/10 , C12P7/16 , C12P19/02 , C12P19/04 , C12P19/12 , C12P19/14 , C12P39/00 , C12P2203/00 , Y02E50/10 , Y02E50/16 , Y02E50/17
摘要： The present disclosure realtes to co-culture compositions containing a population of lignocellulolytic cells containing a mutation in one or more β-glucosidase genes, and a population of fermentative microorganisms; and to methods for using such co-culture compositions for producing commodity chemicals, such as biofuels, from lignocellulosic biomass.
摘要翻译：本公开涉及包含含有一个或多个β-葡糖苷酶基因中的突变的木质纤维素分解细胞群和发酵微生物群的共培养组合物; 以及使用这种共培养组合物从木质纤维素生物质生产诸如生物燃料的商品化学品的方法。

43. 发明申请

WO2011052819A1 글리세롤로부터 3-하이드록시프로피온산을 생산하는 새로운 방법 审中-公开
标题翻译：从甘油生产3-羟基丙酸的新方法
公开(公告)号：WO2011052819A1
公开(公告)日：2011-05-05
申请号：PCT/KR2009/006278
申请日：2009-10-29
申请人： 한국생명공학연구원 , 김철호 , 서정우 , 라련화 , 오백록 , 서필수 , 허선연
发明人： 김철호 , 서정우 , 라련화 , 오백록 , 서필수 , 허선연
IPC分类号： C12P7/18 , C12N1/21 , C12N15/53
CPC分类号： C12P7/42 , C07K14/26 , C12N9/0006 , C12N9/0008 , C12P7/18 , C12P7/52
摘要： 본 발명은 글리세롤을 이용하여 3-하이드록시프로피온산을 제조하는 새로운 방법에 관한 것으로, 더욱 자세하게는 코엔자임 B12 생성능을 가지고, 글리세롤을 탄소원으로하여 3-하이드록시프로피온산을 생산하는 능력을 가지는 미생물에서 알데히드 디하이드로게나아제를 코딩하는 유전자를 증폭시킨 변이 미생물을 글리세롤 함유 배지에서 배양하여 3-하이드록시프로피온산을 제조하는 방법에 관한 것이다. 본 발명에 따르면, 코엔자임 B12를 추가할 필요가 없으며, microaerobic 혹은 aerobic 조건에서도 글리세롤의 발효가 가능하기 때문에 3-하이드록시프로피온산의 대량 생산을 위한 생물 공정 개발에 매우 적합할 것으로 판단된다.
摘要翻译：本发明涉及一种使用甘油制备3-羟基丙酸的新方法，更具体地涉及通过培养突变型微生物制备3-羟基丙酸的方法，其中编码醛脱氢酶的基因在包含在微生物中的含有甘油的培养基中扩增能够使用甘油作为碳源产生3-羟基丙酸，并具有产生腺苷钴胺的能力。公开了大量生产3-羟基丙酸的生物工艺开发，因为甘油可以在微需氧或需氧条件下发酵，并且不需要任何另外的腺苷钴胺。

44. 发明申请

WO2004057018A2 VIRULENCE GENES, PROTEINS, AND THEIR USE 审中-公开
标题翻译：病毒基因，蛋白质及其使用
公开(公告)号：WO2004057018A2
公开(公告)日：2004-07-08
申请号：PCT/CH2003/000836
申请日：2003-12-19
申请人： UNIVERSITY OF GENEVA , COSSON, Pierre , KÖHLER, Thilo , BENGHEZAL, Mohammed , MARCHETTI, Anna , VAN DELDEN, Christian
发明人： COSSON, Pierre , KÖHLER, Thilo , BENGHEZAL, Mohammed , MARCHETTI, Anna , VAN DELDEN, Christian
IPC分类号： C12Q1/00
CPC分类号： C07K14/26 , A61K2039/522 , C07K14/21
摘要： A series of genes from Pseudomonas aeruginosa and Klebsiella are shown to encode products that are implicated in virulence. The identification of theses genes therefore allows attenuated microorganisms to be produced. Furthermore, the genes or their encoded products can be used to identify antimicrobial drugs, diagnostic methods for the identification of a pathogen-associated disease, and in the manufacture of vaccines.
摘要翻译：来自铜绿假单胞菌和克雷伯菌的一系列基因显示出编码与毒力有关的产物。因此，这些基因的鉴定允许产生减毒的微生物。此外，基因或其编码产物可用于鉴定抗微生物药物，用于鉴定病原体相关疾病的诊断方法和疫苗的制造。

45. 发明申请

WO00050071A1 PROTEIN OmpA OF KLEBSIELLA PNEUMONIAE ASSOCIATED WITH THE HCG HORMONE OR A COMPOUND INVOLVED IN CELL PROLIFERATION OR FERTILITY 审中-公开
标题翻译：与HCG HORMONE或细胞增殖或功能相关的化合物相关的KlebsiellA PNEUMONIA的蛋白质OmpA
公开(公告)号：WO00050071A1
公开(公告)日：2000-08-31
申请号：PCT/FR2000/000463
申请日：2000-02-24
IPC分类号： A61K39/385 , A61K39/39 , A61P15/08 , A61P35/00 , A61P37/00 , A61P37/04 , C07K14/26 , C07K14/59 , A61K39/00 , A61K48/00
CPC分类号： C07K14/26 , A61K39/385 , A61K39/39 , A61K2039/55516 , A61K2039/6068 , C07K14/59 , C07K2319/00 , C12N2799/021
摘要： The invention concerns the use of a mixture or complex comprising an enterobacterium membrane protein OmpA, in particular of Klebsiella pneumoniae, associated with an immunogen selected among the beta hCG, a compound involved in tumour cell proliferation or fertility, or with one of their fragments, for preparing a pharmaceutical composition for enhancing the response against said immunogen. The invention further concerns a pharmaceutical composition comprising said mixture or complex in particular for preventing and for treating tumours, or for treating fertility.
摘要翻译：本发明涉及包含肠细菌膜蛋白OmpA，特别是肺炎克雷伯氏杆菌的混合物或复合物的用途，所述肠杆菌膜蛋白OmpA与选自βhCG，参与肿瘤细胞增殖或生育的化合物或其片段之一的免疫原相关，用于制备用于增强针对所述免疫原的应答的药物组合物。本发明还涉及包含所述混合物或复合物的药物组合物，特别是用于预防和治疗肿瘤，或用于治疗生育力。

46. 发明申请

WO9820157A3 Species-specific, genus-specific and universal DNA probes and amplification primers to rapidly detect and identify common bacterial and fungal pathogens and associated antibiotic resistance genes from clinical specimens for diagnosis in microbiology laboratories 审中-公开
标题翻译：物种特异性，属特异性和通用DNA探针和扩增引物，用于快速检测和鉴定临床标本中常见的细菌和真菌病原体和相关抗生素抗性基因，用于微生物实验室的诊断
公开(公告)号：WO9820157A3
公开(公告)日：1998-08-13
申请号：PCT/CA9700829
申请日：1997-11-04
申请人： INFECTIO DIAGNOSTIC INC , BERGERON MICHEL G , PICARD FRANCOIS J , OUELETTE MARC , ROY PAUL H
发明人： BERGERON MICHEL G , PICARD FRANCOIS J , OUELLETTE MARC , ROY PAUL H
IPC分类号： C12N15/09 , C07K14/195 , C07K14/21 , C07K14/245 , C07K14/26 , C07K14/285 , C07K14/31 , C07K14/315 , C12N1/21 , C12Q1/68 , C12R1/01
CPC分类号： C12Q1/689 , C07K14/195 , C07K14/21 , C07K14/212 , C07K14/245 , C07K14/26 , C07K14/285 , C07K14/31 , C07K14/315 , C07K14/3156 , C12Q1/6895 , C12Q2600/156
摘要： DNA-based methods employing amplification primers or probes for detecting, identifying, and quantifying in a test sample DNA from (i) any bacterium, (ii) the species Streptococcus agalactiae, Staphylococcus saprophyticus, Enterococcus faecium, Neisseria meningitidis, Listeria monocytogenes and Candida albicans, and (iii) any species of the genera Streptococcus, Staphylococcus, Enterococcus, Neisseria and Candida are disclosed. DNA-based methods employing amplification primers or probes for detecting, identifying, and quantifying in a test sample antibiotic resistance genes selected from the group consisting of blatem, blarob, blashv, blaoxa, blaZ, aadB, aacC1, aacC2, aacC3, aacA4, aac6'-IIa, ermA, ermB, ermC, mecA, vanA, vanB, vanC, satA, aac(6'-aph(2''), aad(6'), vat, vga, msrA, sul and int are also disclosed. The above microbial species, genera and resistance genes are all clinically relevant and commonly encountered in a variety of clinical specimens. These DNA-based assays are rapid, accurate and can be used in clinical microbiology laboratories for routine diagnosis. These novel diagnostic tools should be useful to improve the speed and accuracy of diagnosis of microbial infections, thereby allowing more effective treatments. Diagnostic kits for (i) the universal detection and quantification of bacteria, and/or (ii) the detection, identification and quantification of the above-mentioned bacterial and fungal species and/or genera, and/or (iii) the detection, identification and quantification of the above-mentioned antibiotic resistance genes are also claimed.
摘要翻译：基于DNA的方法，使用扩增引物或探针来检测，鉴定和定量来自（i）任何细菌的测试样品DNA，（ii）无乳链球菌，腐生葡萄球菌，屎肠球菌，脑膜炎奈瑟氏球菌，单核细胞增生利斯特氏菌和白色念珠菌，和（iii）任何种属的链球菌属，葡萄球菌属，肠球菌属，奈瑟球菌属和假丝酵母属。基于DNA的方法，使用扩增引物或探针来检测，鉴定和定量测试样品抗生素抗性基因，其选自bla tem，bla rob，bla shv，bla oxa，blaZ，aadB，aacC1，aacC2，aacC3 ，aacA4，aac6'-IIa，ermA，ermB，ermC，mecA，vanA，vanB，vanC，satA，aac（6'） - aph（2“），aad（6'），vat，vga，msrA，上述微生物种类，属和抗性基因全部临床相关，常见于各种临床标本，这些基于DNA的检测方法快速，准确，可用于临床微生物实验室进行常规诊断。诊断工具可用于提高微生物感染诊断的速度和准确性，从而允许更有效的治疗。诊断试剂盒用于（i）细菌的普遍检测和定量，和/或（ii）检测，鉴定和定量的上述细菌和/或类，和/或（iii）上述抗生素抗性基因的检测，鉴定和定量也被要求保护。

47. 发明授权

US09957509B2 Synthetic gene clusters 有权
公开(公告)号：US09957509B2
公开(公告)日：2018-05-01
申请号：US15288916
申请日：2016-10-07
申请人： The Regents of the University of California
发明人： Ethan Mirsky , Karsten Temme , Christopher A. Voigt , Dehua Zhao
IPC分类号： C12N15/63 , G06F19/22 , G06F19/20 , C07K14/26 , C12N9/02
CPC分类号： C12N15/635 , C07K14/255 , C07K14/26 , C12N9/0095 , C12N15/52 , C12N15/63 , C12N15/67 , C12N15/74 , C12Y118/06001 , G06F19/20 , G06F19/22
摘要： Methods for making synthetic gene clusters are described.

48. 发明授权

US08623620B2 Microorganism which produces L-amino acid and method for producing L-amino acid using the same 有权
标题翻译：产生L-氨基酸的微生物和使用其生产L-氨基酸的方法
公开(公告)号：US08623620B2
公开(公告)日：2014-01-07
申请号：US13254072
申请日：2010-02-16
申请人： Jae Yeong Ju , Kwang Ho Lee , Hyun Ae Bae
发明人： Jae Yeong Ju , Kwang Ho Lee , Hyun Ae Bae
IPC分类号： C12N9/24
CPC分类号： C12P13/04 , C07K14/26 , C12N9/1205 , C12P13/08
摘要： The present invention relates to a microorganism belonging to the genus Escherichia sp. and a method for producing L-amino acid using the same. The microorganism belonging to the genus Escherichia sp. has a sucrose assimilability and L-amino acid producing ability, which is obtained by introducing a gene encoding a sucrose assimilative microorganism-derived sucrose metabolic enzyme to sucrose non-assimilative microorganism belonging to the genus Escherichia sp. having an L-amino acid producing ability and sucrose PTS (phosphoenolpyruvate dependent sucrose phosphotransferase system) activity.
摘要翻译：本发明涉及属于埃希氏菌属的微生物。以及使用其制造L-氨基酸的方法。属于埃希氏菌属的微生物具有蔗糖同化性和L-氨基酸产生能力，其通过将编码蔗糖同化微生物的蔗糖代谢酶的基因导入属于埃希氏菌属的蔗糖非同化微生物而获得。具有L-氨基酸生产能力和蔗糖PTS（磷酸烯醇丙酮酸依赖性蔗糖磷酸转移酶系统）活性。

49. 发明授权

US07943346B2 Probes and primers for detection of bacterial pathogens and antibiotic resistance genes 有权
标题翻译：用于检测细菌病原体和抗生素抗性基因的探针和底物
公开(公告)号：US07943346B2
公开(公告)日：2011-05-17
申请号：US11416499
申请日：2006-05-01
申请人： Michel G. Bergeron , Marc Ouellette , Paul H. Roy
发明人： Michel G. Bergeron , Marc Ouellette , Paul H. Roy
IPC分类号： C12P19/34 , C07H21/04
CPC分类号： C07K14/315 , C07K14/195 , C07K14/21 , C07K14/212 , C07K14/245 , C07K14/26 , C07K14/285 , C07K14/31 , C07K14/3156 , C12Q1/689 , C12Q1/6895 , C12Q2600/16
摘要： The present invention relates to methods for universal bacterial detection, for specific detection of the common bacterial pathogens, and for specific detection of commonly encountered and clinically relevant bacterial antibiotic resistance genes directly from clinical specimens or, alternatively, from a bacterial colony. The core of this invention consists primarily of the DNA sequences from all species-specific genomic DNA fragments selected by hybridization from genomic libraries or, alternatively, selected from data banks as well as any oligonucleotide sequences derived from these sequences which can be used as probes or amplification primers for PCR or any other nucleic acid amplification methods. This invention also includes DNA sequences from the selected clinically relevant antibiotic resistance genes. Diagnostic kits comprising such primers and probes are also provided.
摘要翻译：本发明涉及通用细菌检测方法，用于特异性检测常见细菌病原体，以及直接从临床标本或细菌菌落特异性检测常见且临床相关的细菌抗生素抗性基因。本发明的核心主要由来自基因组文库杂交选择的所有物种特异性基因组DNA片段的DNA序列组成，或者选自数据库，以及衍生自可用作探针的这些序列的任何寡核苷酸序列，用于PCR的扩增引物或任何其它核酸扩增方法。本发明还包括来自所选择的临床相关抗生素抗性基因的DNA序列。还提供了包括这种引物和探针的诊断试剂盒。

50. 发明授权

US07758863B2 Replikin peptides in rapid replication of glioma cells and in influenza epidemics 失效
标题翻译：复制素肽在胶质瘤细胞和流行性感冒流行中的快速复制
公开(公告)号：US07758863B2
公开(公告)日：2010-07-20
申请号：US12412888
申请日：2009-03-27
申请人： Samuel Bogoch , Elenore S. Bogoch
发明人： Samuel Bogoch , Elenore S. Bogoch
IPC分类号： A61K39/145 , C07K4/00 , C07K14/00
CPC分类号： C07K14/005 , A61K38/00 , A61K39/00 , A61K2039/505 , A61K2039/53 , C07K14/195 , C07K14/205 , C07K14/21 , C07K14/22 , C07K14/24 , C07K14/245 , C07K14/255 , C07K14/26 , C07K14/27 , C07K14/28 , C07K14/285 , C07K14/30 , C07K14/305 , C07K14/31 , C07K14/315 , C07K14/32 , C07K14/33 , C07K14/335 , C07K14/34 , C07K14/345 , C07K14/35 , C07K14/355 , C07K14/36 , C07K14/37 , C07K14/38 , C07K14/385 , C07K14/39 , C07K14/40 , C07K14/405 , C07K14/415 , C07K14/44 , C07K14/445 , C07K14/47 , C12N2710/24122 , C12N2760/16022 , C12N2760/16122 , Y02A50/412
摘要： Peptides of influenza virus hemagglutinin protein and Plasmodium falciparum malaria antigen, antibodies specific for the peptides, influenza vaccines, malaria vaccines and methods of stimulating the immune response of a subject to produce antibodies to influenza virus or malaria are disclosed. Also disclosed are methods for formulating vaccines for influenza virus.
摘要翻译：公开了流感病毒血凝素蛋白和恶性疟原虫疟疾抗原肽，肽特异性抗体，流感疫苗，疟疾疫苗和刺激受试者的免疫应答以产生抗流感病毒或疟疾的方法。还公开了用于制定用于流感病毒的疫苗的方法。

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式