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41. 发明申请

US20120217826A1 COOLING DEVICE 有权
标题翻译：冷却装置
公开(公告)号：US20120217826A1
公开(公告)日：2012-08-30
申请号：US13404877
申请日：2012-02-24
申请人： Mao Xiong Jiang , Yu Li , Gang Li , Yong Wang , Hai Hui Xiang
发明人： Mao Xiong Jiang , Yu Li , Gang Li , Yong Wang , Hai Hui Xiang
IPC分类号： H02K9/19 , F28F3/12 , F28D15/00
CPC分类号： H02K5/20
摘要： A cooling device includes an inner sleeve with an outer surface, an outer sleeve surrounding the inner sleeve, and two end portions extending between the inner sleeve and the outer sleeve at the ends. The inner sleeve, the outer sleeve and the end portions define a peripheral space. A flow guiding structure defines N channels in the peripheral space for coolant to flow, where N is an integer equal to or greater than 1. Each channel has at least two branches, and N pairs of inlet and outlet corresponding to the N channels. The branches of each channel are in fluid communication with a respective pair of inlet and outlet. Each branch extends over a half circumferential part of the outer surface of the inner sleeve. An electric motor incorporating the cooling device is also provided.
摘要翻译：冷却装置包括具有外表面的内套筒，围绕内套筒的外套筒和在端部处在内套筒和外套筒之间延伸的两个端部。内套筒，外套筒和端部限定外围空间。流动引导结构在外围空间中定义了N个通道以使冷却剂流动，其中N是等于或大于1的整数。每个通道具有至少两个分支，并且N对对应于N个通道的入口和出口。每个通道的分支与相应的一对入口和出口流体连通。每个分支延伸到内套筒的外表面的半圆周部分上。还提供了包括冷却装置的电动机。

42. 发明授权

US08175862B1 Model-based systems and methods for monitoring resources 有权
标题翻译：用于监控资源的基于模型的系统和方法
公开(公告)号：US08175862B1
公开(公告)日：2012-05-08
申请号：US13179405
申请日：2011-07-08
申请人： Dmitri Bourlatchkov , Brendan Behan , Yu Li , Nils Meier , Leo Pechersky , Steven P. Rosenberg , Geoff Vona
发明人： Dmitri Bourlatchkov , Brendan Behan , Yu Li , Nils Meier , Leo Pechersky , Steven P. Rosenberg , Geoff Vona
IPC分类号： G06F17/50
CPC分类号： G06F11/3409
摘要： Modeling systems and methods for constructing one or more models of a computing system using collected data. Certain model-based systems build topology models and/or model instances by transforming collected performance data into a collection-location independent form. In certain examples, systems include at least one agent for collecting performance data from monitored resource(s), canonical data transform (CDT) configurations, and a data transformation module for performing data transform operation(s) on the performance data based on at least one CDT configuration. The data transform operation may include generating and/or updating a topology model, assigning metrics to model object(s), updating properties of model object(s), creating associations between existing model objects, or the like. Certain systems and methods also allow for a single piece of data to be processed by multiple models or for pieces of data collected from different locations to be matched and/or associated with the same model object.
摘要翻译：使用收集的数据构建计算系统的一个或多个模型的建模系统和方法。某些基于模型的系统通过将收集的性能数据转换为与集合位置无关的形式来构建拓扑模型和/或模型实例。在某些示例中，系统包括至少一个代理，用于从所监视的资源，规范数据变换（CDT）配置收集性能数据，以及用于至少基于演示数据执行数据变换操作的数据变换模块一个CDT配置。数据变换操作可以包括生成和/或更新拓扑模型，向模型对象分配度量，更新模型对象的属性，创建现有模型对象之间的关联等。某些系统和方法还允许单个数据由多个模型或从不同位置收集的数据进行处理以与同一模型对象匹配和/或关联。

43. 发明申请

US20120002859A1 MAGNETIC RESONANCE PARTIALLY PARALLEL IMAGING (PPI) WITH MOTION CORRECTED COIL SENSITIVITIES 审中-公开
标题翻译：具有运动校正线圈敏感度的磁共振部分平行成像（PPI）
公开(公告)号：US20120002859A1
公开(公告)日：2012-01-05
申请号：US13254468
申请日：2010-02-09
申请人： Feng Huang , Wei Lin , Yu Li
发明人： Feng Huang , Wei Lin , Yu Li
IPC分类号： G06K9/00
CPC分类号： G01R33/5611 , G01R33/56509
摘要： Magnetic resonance (MR) imaging performed in cooperation with an MR scanner (10) uses a method comprising: (i) acquiring sensitivity maps (34) for a plurality of radio frequency coils using a MR pre scan (50) performed by the MR scanner; (ii) acquiring an MR imaging data set (38) using the plurality of radio frequency coils and the MR scanner; and (iii) reconstructing (62, 78) the MR imaging data set using partially parallel image reconstruction employing the sensitivity maps and a correction for subject motion between the acquiring (i) and the acquiring (ii).
摘要翻译：与MR扫描器（10）协作执行的磁共振（MR）成像使用一种方法，包括：（i）使用由MR扫描器执行的MR预扫描（50）获取多个射频线圈的灵敏度图（34） ; （ii）使用所述多个射频线圈和所述MR扫描器获取MR成像数据集（38）; 以及（iii）使用使用灵敏度图的部分平行图像重建和在获取（i）和获取（ii）之间的主题运动的校正来重建（62,78）MR成像数据集。

44. 发明申请

US20110014283A1 NOVEL DOSAGE FORM 审中-公开
标题翻译：新的剂量形式
公开(公告)号：US20110014283A1
公开(公告)日：2011-01-20
申请号：US12528492
申请日：2008-02-28
申请人： Allan James Clarke , David Geoffrey Cullingford , Yu Li
发明人： Allan James Clarke , David Geoffrey Cullingford , Yu Li
IPC分类号： A61K9/30 , A61K31/55
CPC分类号： A61K31/55 , A61K9/0056 , A61K9/2018 , A61K9/2027 , A61K9/2054 , A61K9/2059 , A61K9/209 , A61K9/282 , A61K9/2866
摘要： The present invention relates to a novel dosage form, to a process for preparing the dosage form and to the use of the dosage form in the treatment of neurological and psychiatric disorders.
摘要翻译：本发明涉及一种新的剂型，一种制备该剂型的方法以及该剂型在治疗神经和精神疾病中的用途。

45. 发明申请

US20100151495A9 Reagents for the detection of protein phosphorylation in carcinoma signaling pathways 审中-公开
标题翻译：用于检测癌症信号通路中蛋白质磷酸化的试剂
公开(公告)号：US20100151495A9
公开(公告)日：2010-06-17
申请号：US12074228
申请日：2008-02-29
申请人： Roberto Polakiewicz , Ailan Guo , Albrecht Moritz , Klarisa Rikova , Kimberly Lee , Erik Spek , Yu Li , Charles Farnsworth
发明人： Roberto Polakiewicz , Ailan Guo , Albrecht Moritz , Klarisa Rikova , Kimberly Lee , Erik Spek , Yu Li , Charles Farnsworth
IPC分类号： G01N33/53 , C07K16/18 , C07K14/00 , C12N5/18
CPC分类号： C07K16/44 , G01N33/57426
摘要： The invention discloses nearly 443 novel phosphorylation sites identified in signal transduction proteins and pathways underlying human carcinoma, and provides phosphorylation-site specific antibodies and heavy-isotope labeled peptides (AQUA peptides) for the selective detection and quantification of these phosphorylated sites/proteins, as well as methods of using the reagents for such purpose. Among the phosphorylation sites identified are sites occurring in the following protein types: Protein kinases (including Serine/Threonine dual specificity, and Tyrosine kinases), Adaptor/Scaffold proteins, Transcription factors, Phospoatases, Tumor supressors, Ubiquitin conjugating system proteins, Translation initiation complex proteins, RNA binding proteins, Apoptosis proteins, Adhesion proteins, G protein regulators/GTPase activating protein/Guanine nucleotide exchange factor proteins, and DNA binding/replication/repair proteins, as well as other protein types.
摘要翻译：本发明公开了在信号转导蛋白中鉴定的近443个新的磷酸化位点和人癌基因的途径，并提供磷酸化位点特异性抗体和重同位素标记肽（AQUA肽），用于选择性检测和定量这些磷酸化位点/蛋白质，如以及使用试剂用于此目的的方法。鉴定的磷酸化位点是发生在以下蛋白质类型中的位点：蛋白激酶（包括丝氨酸/苏氨酸双特异性和酪氨酸激酶），适配器/支架蛋白，转录因子，磷酸酶，肿瘤抑制因子，泛素缀合系统蛋白，翻译起始复合体蛋白质，RNA结合蛋白，细胞凋亡蛋白，粘附蛋白，G蛋白调节剂/ GTPase激活蛋白/鸟嘌呤核苷酸交换因子蛋白，以及DNA结合/复制/修复蛋白，以及其他蛋白质类型。

46. 发明申请

US20100015724A1 LYSINE ACETYLATION SITES 审中-公开
标题翻译： LYSINE乙酰化网站
公开(公告)号：US20100015724A1
公开(公告)日：2010-01-21
申请号：US12310279
申请日：2007-08-17
申请人： Peter Hornbeck , Ting-Lie Gu , Ailan Guo , Charles Farnsworth , Yu Li , Jeffrey Mitchell
发明人： Peter Hornbeck , Ting-Lie Gu , Ailan Guo , Charles Farnsworth , Yu Li , Jeffrey Mitchell
IPC分类号： G01N33/53 , C07K16/00
CPC分类号： C07K16/44 , A61K38/00 , G01N33/574 , G01N2500/04
摘要： The invention discloses 332 novel acetylation sites identified in various cancers, peptides (including AQUA peptides) comprising a acetylation site of the invention, antibodies specifically bind to a novel acetylation site of the invention, and diagnostic and therapeutic uses of the above.
摘要翻译：本发明公开了在各种癌症中鉴定的332个新的乙酰化位点，包含本发明的乙酰化位点的肽（包括AQUA肽），特异性结合本发明的新型乙酰化位点的抗体，以及上述的诊断和治疗用途。

47. 发明申请

US20090258442A1 Reagents for the detection of protein phosphorylation in carcinoma signaling pathways 审中-公开
标题翻译：用于检测癌症信号通路中蛋白质磷酸化的试剂
公开(公告)号：US20090258442A1
公开(公告)日：2009-10-15
申请号：US12074199
申请日：2008-02-29
申请人： Roberto Polakiewicz , Ailan Guo , Albrecht Moritz , Klarisa Rikova , Kimberly Lee , Erik Spek , Yu Li , Charles Farnsworth
发明人： Roberto Polakiewicz , Ailan Guo , Albrecht Moritz , Klarisa Rikova , Kimberly Lee , Erik Spek , Yu Li , Charles Farnsworth
IPC分类号： G01N33/536 , C07K16/18
CPC分类号： C07K16/30 , C07K16/44 , G01N33/57426 , G01N33/57496
摘要： The invention discloses nearly 474 novel phosphorylation sites identified in signal transduction proteins and pathways underlying human carcinoma, and provides phosphorylation-site specific antibodies and heavy-isotope labeled peptides (AQUA peptides) for the selective detection and quantification of these phosphorylated sites/proteins, as well as methods of using the reagents for such purpose. Among the phosphorylation sites identified are sites occurring in the following protein types: Kinase, Adaptor/Scaffold proteins, Phosphatase, G protein Regulator/Guanine Nucleotide Exchange Factors/GTPase Activating Proteins, Cytoskeleton Proteins, DNA Binding Proteins, Phospholipase, Receptor Proteins, Enzymes, DNA Repair/Replication Proteins, Adhesion Proteins, and Proteases, as well as other protein types.
摘要翻译：本发明公开了在信号转导蛋白中鉴定的近474个新的磷酸化位点和人癌基因的途径，并提供磷酸化位点特异性抗体和重同位素标记肽（AQUA肽），用于选择性检测和定量这些磷酸化位点/蛋白质，如以及使用试剂用于此目的的方法。鉴定的磷酸化位点是发生在以下蛋白质类型中的位点：激酶，适配器/支架蛋白，磷酸酶，G蛋白调节剂/鸟嘌呤核苷酸交换因子/ GTP酶活化蛋白，细胞骨架蛋白，DNA结合蛋白，磷脂酶，受体蛋白，酶， DNA修复/复制蛋白，粘附蛋白和蛋白酶，以及其他蛋白质类型。

48. 发明申请

US20090098581A1 Tyrosine phosphorylation sites 有权
标题翻译：酪氨酸磷酸化位点
公开(公告)号：US20090098581A1
公开(公告)日：2009-04-16
申请号：US12148547
申请日：2008-04-18
申请人： Peter Hornbeck , Ailan Guo , Ting-Lei Gu , Klarisa Rikova , Albrecht Moritz , Charles Farnsworth , Matthew Stokes , Jian Yu , Erik Spek , Yu Li , Anthony Possemato , Jessica Cherry , Valerie Goss , Jeffrey Mitchell , John Rush , Corinne Michaud
发明人： Peter Hornbeck , Ailan Guo , Ting-Lei Gu , Klarisa Rikova , Albrecht Moritz , Charles Farnsworth , Matthew Stokes , Jian Yu , Erik Spek , Yu Li , Anthony Possemato , Jessica Cherry , Valerie Goss , Jeffrey Mitchell , John Rush , Corinne Michaud
IPC分类号： G01N33/574 , C07K16/30 , G01N33/566
CPC分类号： G01N33/6842 , C07K16/30 , C07K16/44 , C07K2317/34 , G01N33/57407 , G01N33/57426
摘要： The invention discloses 482 novel phosphorylation sites identified in carcinoma and/or leukemia, peptides (including AQUA peptides) comprising a phosphorylation site of the invention, antibodies specifically bind to a novel phosphorylation site of the invention, and diagnostic and therapeutic uses of the above.
摘要翻译：本发明公开了在癌和/或白血病中鉴定的482个新的磷酸化位点，包含本发明的磷酸化位点的肽（包括AQUA肽），特异性结合本发明的新的磷酸化位点的抗体，以及上述的诊断和治疗用途。

49. 发明申请

US20080153347A1 Battery Connector 审中-公开
标题翻译：电池连接器
公开(公告)号：US20080153347A1
公开(公告)日：2008-06-26
申请号：US11613271
申请日：2006-12-20
申请人： Ming-Chun Lai , Yu Li
发明人： Ming-Chun Lai , Yu Li
IPC分类号： H01R3/00
CPC分类号： H01R13/2442
摘要： A battery connector includes a housing having a terminal recess and a plurality of electric terminals. The terminal recess has an inlay recess in the bottom of the terminal recess and a receiving cavity extending from the top of the terminal recess to the inlay recess, and an opening is dug at the end of the inlay recess. The electric terminal comprises a base portion, a contacting portion and a soldering portion. The base portion is received in the inlay recess. The contacting portion extends out of the receiving cavity for connecting the battery. The soldering portion was exposed by the opening of the housing. The repairman can replenish solder to the soldering portion by the opening of the housing if the machine omits soldering the soldering portion of the battery connector during excessive production.
摘要翻译：电池连接器包括具有端子凹部和多个电端子的壳体。端子凹部在端子凹槽的底部具有凹槽，并且从端子凹部的顶部延伸到嵌入凹槽，并且在嵌入凹槽的端部挖出开口。电气端子包括基部，接触部和焊接部。基部被容纳在嵌体凹部中。接触部分延伸出接收腔，用于连接电池。焊接部分被壳体的开口暴露。如果在过度生产过程中机器省略焊接电池连接器的焊接部分，修理工可以通过外壳的打开将焊料补充到焊接部分。

50. 发明申请

US20080116919A1 FPGA AND METHOD AND SYSTEM FOR CONFIGURING AND DEBUGGING A FPGA 有权
标题翻译：用于配置和调试FPGA的FPGA和方法和系统
公开(公告)号：US20080116919A1
公开(公告)日：2008-05-22
申请号：US11944408
申请日：2007-11-21
申请人： Yu Li , Guo Hui Lin , Qiang Liu , Yu Dong Yang
发明人： Yu Li , Guo Hui Lin , Qiang Liu , Yu Dong Yang
IPC分类号： G01R31/02
CPC分类号： G01R31/31705 , G01R31/318519
摘要： The present invention provides a Field Programmable Gate Array (FPGA), a system for debugging a Field Programmable Gate Array, a method for debugging a Field Programmable Gate Array, a FPGA configuration data product and a method and system for configuring a FPGA. According to one aspect of the invention, there is provided a Field Programmable Gate Array (FPGA) having a logic unit under test and comprising: a probe signal selecting unit configured to select at least one probe point from a plurality of probe points in said logic unit under test, and obtain a probe signal at said probe point; and a high speed serial transceiver configured to convert said probe signal into a high speed serial signal and transmit it to outside.
摘要翻译：本发明提供了现场可编程门阵列（FPGA），用于调试现场可编程门阵列的系统，用于调试现场可编程门阵列的方法，FPGA配置数据产品以及用于配置FPGA的方法和系统。根据本发明的一个方面，提供了一种具有被测逻辑单元的现场可编程门阵列（FPGA），包括：探测信号选择单元，被配置为从所述逻辑中的多个探测点中选择至少一个探测点并在所述探测点获取探测信号; 以及配置成将所述探测信号转换为高速串行信号并将其传输到外部的高速串行收发器。

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