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41. 发明授权

US3954730A 6-(Substituted-cycloalkylcarboxamide) penicillanic acids 失效
标题翻译： 6-（取代的环烷基甲酰胺）青霉烷酸
公开(公告)号：US3954730A
公开(公告)日：1976-05-04
申请号：US516359
申请日：1974-10-21
申请人： Karl Georg Metzger , Gunther Schmidt
发明人： Karl Georg Metzger , Gunther Schmidt
IPC分类号： A23K20/195 , C07D499/00 , C07D499/74
CPC分类号： C07C253/30 , C07C17/26 , C07D499/00 , C07C2101/04
摘要： Penicillins of the formula ##SPC1##Or a pharmaceutically-acceptable, nontoxic salt thereof,WhereinR.sub.1 and R.sub.2 are the same or different and each is hydrogen, fluorine, chlorine or bromine; or when R.sub.2 is hydrogen, R.sub.1 can also be cyano, hydroxyl, azido, amino or nitro; orR.sub.1 and R.sub.2 are bonded to a ring carbon atom and constitute a single oxygen atom;R.sub.3 is hydrogen, methyl, chlorine, bromine, cyano, methoxy or carboxyl; andn is 2 to 7;Are useful for their antibacterial activity.
摘要翻译：式OR的青霉素或其药物可接受的非酮性盐，其中R 1和R 2相同或不同，各自为氢，氟，氯或溴; 或当R 2为氢时，R 1也可为氰基，羟基，叠氮基，氨基或硝基; 或R 1和R 2与环碳原子键合并构成单个氧原子; R3是氢，甲基，氯，溴，氰基，甲氧基或羧基; 和N IS 2至7; 有用于其抗菌活性。

42. 发明授权

US08338621B2 Process for the preparation of 2-oxo-1-pyrrolidine derivatives 失效
标题翻译： 2-氧代-1-吡咯烷衍生物的制备方法
公开(公告)号：US08338621B2
公开(公告)日：2012-12-25
申请号：US11612654
申请日：2006-12-19
申请人： John Surtees , Didier Bouvy , Antoine Thomas , Yves Combret , Michael Frank , Gunther Schmidt , Guy Duchene
发明人： John Surtees , Didier Bouvy , Antoine Thomas , Yves Combret , Michael Frank , Gunther Schmidt , Guy Duchene
IPC分类号： C07D207/04
CPC分类号： C07D207/27
摘要： The present invention relates to alternative processes for the preparation of 2-oxo-1-pyrrolidine derivatives of formula (I) Particularly, the present invention relates to alternative processes for the synthesis of levetiracetam, brivaracetam and seletracetam.
摘要翻译：本发明涉及用于制备式（I）的2-氧代-1-吡咯烷衍生物的替代方法。特别地，本发明涉及左乙拉西坦，醋酸乙酰胺和右旋西拉坦的合成的替代方法。

43. 发明授权

US08263780B2 Process for the preparation of 2-imino-thiazolidin-4-one derivatives 有权
标题翻译： 2-亚氨基 - 噻唑烷-4-酮衍生物的制备方法
公开(公告)号：US08263780B2
公开(公告)日：2012-09-11
申请号：US12516055
申请日：2007-11-22
申请人： Stefan Abele , Martin Bolli , Gunther Schmidt
发明人： Stefan Abele , Martin Bolli , Gunther Schmidt
IPC分类号： C07D277/54
CPC分类号： C07D277/54
摘要： The present invention relates to a new process for the preparation of 2-imino-thiazolidin-4-one compounds of the Formula (I) and (II) and to compounds of Formula (II) as such. The present compounds of Formula (II) can be used as intermediates in the preparation of thiazolidin-4-one derivatives of the General Formula (II), which thiazolidin-4-one derivatives being described in WO 2005/054215 to act as immunosuppressive agents.
摘要翻译：本发明涉及制备式（I）和（II）的2-亚氨基 - 噻唑烷-4-酮化合物和式（II）化合物的新方法。本发明的式（II）化合物可以用作制备通式（II）的噻唑烷-4-酮衍生物的中间体，其中WO 2005/054215中描述的噻唑烷-4-酮衍生物作为免疫抑制剂。

44. 发明申请

US20080027625A1 Method for detecting preinjection 失效
标题翻译：检测注射前的方法
公开(公告)号：US20080027625A1
公开(公告)日：2008-01-31
申请号：US11881015
申请日：2007-07-25
申请人： Albert Kloos , Andreas Kunz , Gunther Schmidt , Ralf Speetzen , Michael Willmann
发明人： Albert Kloos , Andreas Kunz , Gunther Schmidt , Ralf Speetzen , Michael Willmann
IPC分类号： F02D41/30
CPC分类号： F02D41/403 , F02D35/027 , F02D41/3809 , F02D2200/0602 , F02M55/025 , F02M2200/40 , Y02T10/44
摘要： A method for detecting a preinjection in an internal combustion engine with a common-rail system, including individual accumulators, in which an individual accumulator pressure distribution is detected in a measurement interval and is used to determine an injection end of the main injection, in which a virtual injection start of the main injection is computed by a mathematical function as a function of the injection end, and in which the virtual injection start is set as the actual injection start of the main injection. With the preinjection activated, an actual injection delay for the main injection is determined as a function of the actual injection start, an injection delay deviation of a set injection delay from the actual injection delay is computed, and the injection delay deviation is used to determine whether a preinjection has occurred.
摘要翻译：一种利用共轨系统（包括各个蓄能器）在内燃机中检测预注射的方法，其中在测量间隔中检测到单独的蓄压器压力分布并用于确定主喷射的喷射端，其中通过作为喷射端的函数的数学函数计算主喷射的虚拟喷射开始，并且将虚拟喷射开始设定为主喷射的实际喷射开始。通过预注射激活，主喷射的实际喷射延迟被确定为实际喷射开始的函数，计算设定的喷射延迟与实际喷射延迟的喷射延迟偏差，并且喷射延迟偏差用于确定是否发生预注意事项。

45. 发明申请

US20080027624A1 Method for controlling an internal combustion engine 失效
标题翻译：用于控制内燃机的方法
公开(公告)号：US20080027624A1
公开(公告)日：2008-01-31
申请号：US11880935
申请日：2007-07-25
申请人： Albert Kloos , Andreas Kunz , Gunther Schmidt , Ralf Speetzen , Michael Willmann
发明人： Albert Kloos , Andreas Kunz , Gunther Schmidt , Ralf Speetzen , Michael Willmann
IPC分类号： F02D41/30
CPC分类号： F02D41/3836 , F02D41/0085 , F02D2200/0602 , F02D2200/0616
摘要： A method for controlling an internal combustion engine with a common-rail system, in which a fuel quantity is computed from a measured fuel pressure distribution and in which the computed fuel quantity is set as the controlling value for controlling an injection. The fuel quantity is computed by measuring the pressure distribution (pE) of an individual accumulator, reproducing a modeled pressure distribution (pEMOD) according to the measured pressure distribution (pE) using a hydraulic model, and computing the fuel quantity from the hydraulic model.
摘要翻译：一种用于通过共轨系统控制内燃机的方法，其中从测量的燃料压力分布计算燃料量，并且其中计算的燃料量被设置为用于控制喷射的控制值。通过测量单个蓄能器的压力分布（pE），使用液压模型根据测量的压力分布（pE）再现建模压力分布（pEMOD）并计算来自液压模型的燃料量来计算燃料量。

46. 发明申请

US20060266332A1 Method of controlling an internal combustion engine 有权
标题翻译：控制内燃机的方法
公开(公告)号：US20060266332A1
公开(公告)日：2006-11-30
申请号：US11499966
申请日：2006-08-07
申请人： Albert Kloos , Michael Willmann , Gunther Schmidt , Ralf Speetzen , Stefan Muller , Andreas Kunz
发明人： Albert Kloos , Michael Willmann , Gunther Schmidt , Ralf Speetzen , Stefan Muller , Andreas Kunz
IPC分类号： F02M65/00 , F02M57/02 , G01M15/00
CPC分类号： F02D41/221 , F02D41/008 , F02D41/3809 , F02D41/402 , F02D2041/2055 , F02D2041/224
摘要： In a method of controlling an internal combustion engine having a common rail fuel injection system including individual fuel storage chambers, wherein the pressure pattern of the fuel supplied to each injector can be determined and actual and virtual fuel injection ends and fuel injection begins are determined, the deviations from the desired fuel injection ends and from the fuel injection begins are calculated and the injectors are evaluated on the basis of the deviations and further control of the internal combustion engine is based on an evaluation of the fuel injectors.
摘要翻译：在具有共轨燃料喷射系统的内燃机的控制方法中，包括单独的燃料储存室，其中可以确定供给每个喷射器的燃料的压力图案，确定实际的燃料喷射结束和燃料喷射的开始，计算出期望燃料喷射结束的偏差和从燃料喷射开始的偏差，并且基于偏差来评估喷射器，并且基于对燃料喷射器的评估来进一步控制内燃机。

47. 发明授权

US05999701A Electrical quick-thawing apparatus 失效
标题翻译：电动快速解冻装置
公开(公告)号：US05999701A
公开(公告)日：1999-12-07
申请号：US101140
申请日：1998-06-26
申请人： Gunther Schmidt
发明人： Gunther Schmidt
IPC分类号： A61M5/178 , A61M1/36 , A61M5/44 , A61F7/00
CPC分类号： A61M5/445
摘要： An electrical quick-thawing apparatus for quickly thawing frozen liquids includes a transmission plate and a clamping and heating device for receiving a container containing a frozen liquid. The clamping and heating device has a heating unit with at least one heating surface and at least one temperature sensor sensing a temperature at the outer wall of the container. An electrical control device including a temperature governor with a control circuit, a set point adjuster, and a switching device controlling heating unit is provided. The output terminal of the temperature sensor is connected to an input terminal of the control circuit. The output terminal of the set point adjuster is connected to an input terminal of the control circuit. The output terminal of the control circuit is connected to the switching device. The switching device controls the heating unit according to signals received from the temperature sensor and the set point adjuster. A highly dynamic linear drive is coupled to the transmission plate and moves transmission plate in a plane. The heating unit is coupled to the transmission plate. The linear drive is embodied as an electromagnetic transducer transforming electrical oscillations into mechanical oscillations at a frequency of 20 to 300 Hz. The electromagnetic transducer has diaphragm moveable in a plane. An oscillation transmission device couples the diaphragm to the transmission plate by a force-locking connection and/or a positive-locking connection.
摘要翻译： PCT No.PCT / DE96 / 02508 Sec。 371日期：1998年6月26日 102（e）日期1998年6月26日PCT 1996年12月23日PCT公布。公开号WO97 / 24152 PCT。日期1997年7月10日用于快速解冻冷冻液体的电快速解冻装置包括用于接收容纳冷冻液体的容器的传动板和夹紧和加热装置。夹紧和加热装置具有至少一个加热表面的加热单元和至少一个感测容器外壁温度的温度传感器。提供一种包括具有控制电路的温度调节器，设定点调节器和控制加热单元的开关装置的电气控制装置。温度传感器的输出端子连接到控制电路的输入端子。设定点调节器的输出端连接到控制电路的输入端。控制电路的输出端子连接到开关装置。开关装置根据从温度传感器和设定点调节器接收的信号来控制加热单元。高度动态的线性驱动器连接到传动板并将传动板移动到平面中。加热单元联接到传输板。线性驱动器被实现为电磁换能器，其将电振荡器以20至300Hz的频率转换成机械振荡。电磁换能器具有可在平面内移动的隔膜。振动传递装置通过力锁定连接和/或正锁定连接将隔膜连接到传动板。

48. 发明授权

US5485986A Furnace with in situ foamed insulation and process for its manufacture 失效
标题翻译：炉内采用原位发泡绝缘及其制造工艺
公开(公告)号：US5485986A
公开(公告)日：1996-01-23
申请号：US193184
申请日：1994-06-02
申请人： Gunther Schmidt , Peter Randel , Hans-Werner Engels , Bernd Geick
发明人： Gunther Schmidt , Peter Randel , Hans-Werner Engels , Bernd Geick
IPC分类号： C04B28/26 , C04B32/00 , C04B38/02 , F27B3/04 , F27B3/12 , F27B3/14 , F27D1/00 , F27D1/16 , C21B7/04
CPC分类号： F27D1/16 , C04B28/26 , F27B3/045 , F27B3/14 , F27D1/0006 , C04B2111/00612 , C04B2111/28 , F27B3/12 , Y02W30/92 , Y02W30/94
摘要： The invention relates to a furnace having an inner wall, an outer wall and a heat insulation arranged in between. The heat insulation is foamed up in situ, and hardened, from a mass which contains,per 100 parts by weight of a reactive solid (stone-forming component),40-250 parts by weight of a water-containing hardener which effects the hardening reaction of the reactive solid (stone-forming component) in the alkaline region,40-250 parts by weight of fillers and a blowing agent.The reactive solid used is preferably a reactive solid from the group comprisingI finely dispersed oxide mixture containing amorphous silica and alumina,II a glassy, amorphous electrostatic precipitator ash,III ground calcined bauxite,IV electrostatic precipitator ash from lignite-fired power stations,V undissolved, amorphous SiO.sub.2, especially from an amorphous, disperse-pulverulent, dehydrated or water-containing silica or from high-temperature processes (silica fume), andVI metakaolin.
摘要翻译： PCT No.PCT / EP92 / 01826 Sec。 371日期：1994年6月2日 102（e）日期1994年6月2日PCT提交1992年8月12日PCT公布。第WO93 / 04010号公报日期：1993年3月4日。本发明涉及一种具有布置在其间的内壁，外壁和绝热体的炉。隔热层原位发泡，硬化，每100重量份反应性固体（石料形成成分）含有40〜250重量份含水硬化剂，其硬化反应性固体（石料形成组分）在碱性区域中的反应，40-250重量份的填料和发泡剂。所使用的反应性固体优选为来自包含无定形二氧化硅和氧化铝的I微细分散氧化物混合物的组的反应性固体，II来自褐煤燃烧电厂的玻璃状无定形静电除尘器灰，III煅烧铝土矿，IV静电除尘器灰，V 未溶解的无定形SiO 2，特别是来自无定形，分散 - 粉状，脱水或含水二氧化硅或高温方法（硅灰）和VI偏高岭土。

49. 发明授权

US5331839A Process for determining the coefficient of friction m.mu. 失效
标题翻译：确定摩擦系数m的方法
公开(公告)号：US5331839A
公开(公告)日：1994-07-26
申请号：US859685
申请日：1992-06-11
申请人： Gunther Schmidt
发明人： Gunther Schmidt
IPC分类号： B60W10/04 , B60T8/172 , B60T8/175 , B60T8/1763 , B60T8/34 , B60T8/42 , B60T8/48 , B60T8/58 , B60W10/18 , G01N19/02
CPC分类号： B60T8/175 , B60T8/172 , B60T8/348 , B60T8/4275 , B60T8/4872 , G01N19/02 , B60T2270/208
摘要： A method for determining the coefficient of friction .mu. between the wheel and the road is described. Assuming a moving vehicle, the brake pressure on a non-driven wheel (measuring wheel) is increased until a tendency to lock occurs. At the same time, the driving torque is increased so that the braking force of the measuring wheel and the increased driving force of the driving wheel on the same vehicle side equal each other. Additionally, an increased driving force of the second driving wheel must be removed by braking.
摘要翻译： PCT No.PCT / EP91 / 00099 Sec。 371日期：1992年6月11日 102（e）日期1992年6月11日PCT 1991年1月19日PCT PCT。 WO91 / 15386 PCT公开号日期：1991年10月17日。描述了用于确定车轮和道路之间的摩擦系数μ的方法。假设移动的车辆，非驱动轮（测量轮）上的制动压力增加，直到发生锁定的趋势。同时，驱动扭矩增加，使得测量轮的制动力和驱动轮在同一车辆侧的增加的驱动力彼此相等。此外，第二驱动轮的驱动力的增加必须通过制动来去除。

50. 发明授权

US4931117A Method for manufacturing frictional locking rings for stepped motor vehicle transmission synchronizing mechanisms 失效
标题翻译：制造阶梯式车辆传动同步机构的摩擦锁环的方法
公开(公告)号：US4931117A
公开(公告)日：1990-06-05
申请号：US116029
申请日：1987-11-03
申请人： Erich R. Muller , Gunther Schmidt , Klaus Hofmeister
发明人： Erich R. Muller , Gunther Schmidt , Klaus Hofmeister
IPC分类号： F16D23/06 , B22F7/00 , B22F7/08 , F16D23/02 , F16D23/04 , F16D65/02 , F16D69/02 , F16D69/04
CPC分类号： F16D69/027 , B22F7/08 , F16D23/025 , F16D69/04 , F16D2065/024 , F16D2069/0458 , F16D2069/0483 , F16D2250/00 , Y10T29/49986
摘要： A method for manufacturing a frictional locking member, in particular a synchronizing ring. The surface of a metallic base member (2) is provided with a frictional body made of a sintering powder.In order to simplify the method, the base member (2) is combined with an insert member (20). The insert member has centering means (24) for retaining the base member (2) in a defined position and at a defined distance (23) from the counter surface (22) arranged at a defined distance (23) from the surface (14). The cavity (27) formed by the defined distance (23) between the surface (14) and the counter surface (22) is filled with a sintering powder, and the insert member (20) is sintered together with the base member (2) with the cavity (27) filled (FIG. 4).
摘要翻译：一种用于制造摩擦锁定构件的方法，特别是同步环。金属基材（2）的表面设置有由烧结粉末制成的摩擦体。为了简化方法，基部构件（2）与插入构件（20）组合。插入构件具有定心装置（24），用于将基座构件（2）保持在与表面（14）限定的距离（23）处布置的相对表面（22）的限定位置和限定距离（23）。由表面（14）和对置面（22）之间的限定距离（23）形成的空腔（27）填充有烧结粉末，插入构件（20）与基底构件（2）一起烧结，其中空腔（27）被填充（图4）。

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