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41. 发明申请

US20060059285A1 System and method for deadlock free bus protection of resources during search execution 有权
标题翻译：搜索执行过程中资源死锁自由总线保护的系统和方法
公开(公告)号：US20060059285A1
公开(公告)日：2006-03-16
申请号：US10942351
申请日：2004-09-15
申请人： Stephen Fischer , Douglas Moran , James Sutton
发明人： Stephen Fischer , Douglas Moran , James Sutton
IPC分类号： G06F13/372
CPC分类号： G06F13/26 , G06F21/74
摘要： A method and system of deadlock free bus protection of memory and I/O resources during secure execution. A bus cycle initiates entry of a bus agent into a secure execution mode. The chipset records an identifier of the secure mode processor. Thereafter, the chipset intercedes if another bus agent attempts a security sensitive bus cycle before the secure mode processor exits the secure mode.
摘要翻译：在安全执行期间，存储器和I / O资源的无死锁总线保护方法和系统。总线周期启动总线代理进入安全执行模式。芯片组记录安全模式处理器的标识符。此后，如果另一个总线代理在安全模式处理器退出安全模式之前尝试安全敏感的总线周期，则芯片组进行中介。

42. 发明申请

US20060020785A1 Secure distribution of a video card public key 审中-公开
标题翻译：安全分发视频卡公钥
公开(公告)号：US20060020785A1
公开(公告)日：2006-01-26
申请号：US10883264
申请日：2004-06-30
申请人： David Grawrock , Willard Wiseman , James Sutton , Clifford Hall , Ned Smith
发明人： David Grawrock , Willard Wiseman , James Sutton , Clifford Hall , Ned Smith
IPC分类号： H04L9/00
CPC分类号： G06F21/84 , G06F21/57
摘要： A system and method for secure distribution of a video card public key. The method provides for loading an authentication code module into a processor, authenticating the authentication code module, and executing the authentication code module. Executing the authentication module causes the authentication code module to assert a hardware indicator to access at least one address in a special protected page on a chipset. Receipt of the hardware indicator by the chipset causes a specific reference to be sent via a dedicated port to a circuit card to retrieve a public key from the circuit card.
摘要翻译：一种用于安全分发视频卡公钥的系统和方法。该方法提供将认证码模块加载到处理器中，认证认证码模块和执行认证码模块。执行认证模块使认证码模块断言硬件指示符访问芯片组中特殊保护页面中的至少一个地址。通过芯片组接收硬件指示符，将特定的参考信号通过专用端口发送到电路卡以从电路卡中取回公钥。

43. 发明申请

US20060015751A1 Method of storing unique constant values 失效
公开(公告)号：US20060015751A1
公开(公告)日：2006-01-19
申请号：US10891699
申请日：2004-07-14
申请人： Ernie Brickell , Alberto Martinez , David Grawrock , James Sutton , Clifford Hall
发明人： Ernie Brickell , Alberto Martinez , David Grawrock , James Sutton , Clifford Hall
IPC分类号： G06F12/14
CPC分类号： G06F21/73
摘要： Secure storage and retrieval of a unique value associated with a device to/from a memory of a processing system. In at least one embodiment, the device needs to be able to access the unique value across processing system resets, and the device does not have sufficient non-volatile storage to store the unique value itself. Instead, the unique value is stored in the processing system memory in such a way that the stored unique value does not create a unique identifier for the processing system or the device. A pseudo-randomly or randomly generated initialization vector may be used to vary an encrypted data structure used to store the unique value in the memory.

44. 发明申请

US20060013402A1 Method of delivering Direct Proof private keys to devices using an on-line service 失效
标题翻译：使用在线服务将Direct Proof私钥交付给设备的方法
公开(公告)号：US20060013402A1
公开(公告)日：2006-01-19
申请号：US10892256
申请日：2004-07-14
申请人： James Sutton , Ernie Brickell , Clifford Hall , David Grawrock
发明人： James Sutton , Ernie Brickell , Clifford Hall , David Grawrock
IPC分类号： H04L9/00
CPC分类号： H04L9/0844 , H04L2209/127
摘要： Delivering a Direct Proof private key to a device installed in a client computer system in the field may be accomplished in a secure manner without requiring significant non-volatile storage in the device. A unique pseudo-random value is generated and stored in the device at manufacturing time. The pseudo-random value is used to generate a symmetric key for encrypting a data structure holding a Direct Proof private key and a private key digest associated with the device. The resulting encrypted data structure is stored on a protected on-liner server accessible by the client computer system. When the device is initialized on the client computer system, the system checks if a localized encrypted data structure is present in the system. If not, the system obtains the associated encrypted data structure from the protected on-line server using a secure protocol. The device decrypts the encrypted data structure using a symmetric key regenerated from its stored pseudo-random value to obtain the Direct Proof private key. If the private key is valid, it may be used for subsequent authentication processing by the device in the client computer system.
摘要翻译：将直接证明私钥提供给安装在该领域中的客户端计算机系统中的设备可以以安全的方式来实现，而不需要设备中的显着的非易失性存储。在制造时产生并存储在设备中的唯一伪随机值。伪随机值用于生成用于加密持有Direct Proof私钥和与该设备相关联的私钥摘要的数据结构的对称密钥。所得到的加密数据结构存储在由客户端计算机系统可访问的受保护的在线服务器上。当在客户端计算机系统上初始化设备时，系统会检查系统中是否存在本地化的加密数据结构。如果没有，系统将使用安全协议从受保护的在线服务器获取相关联的加密数据结构。设备使用从其存储的伪随机值重新生成的对称密钥来解密加密数据结构，以获得直接证明私钥。如果私钥有效，则其可以用于客户端计算机系统中的设备的后续认证处理。

45. 发明申请

US20050228021A1 Adamantylglycine-based inhibitors of dipeptidyl peptidase IV and methods 审中-公开
标题翻译：基于金刚烷基甘氨酸的二肽基肽酶IV抑制剂及方法
公开(公告)号：US20050228021A1
公开(公告)日：2005-10-13
申请号：US11149414
申请日：2005-06-09
申请人： Lawrence Hamann , Ashish Khanna , Mark Kirby , David Magnin , Ligaya Simpkins , James Sutton , Jeffrey Robl
发明人： Lawrence Hamann , Ashish Khanna , Mark Kirby , David Magnin , Ligaya Simpkins , James Sutton , Jeffrey Robl
IPC分类号： C07C255/46 , C07C255/47 , C07D207/16 , C07D209/52 , C07D277/04 , C07D295/185 , A61K31/445 , A61K31/275 , A61K31/401 , A61K31/403 , A61K31/426
CPC分类号： C07C255/46 , C07C255/47 , C07C2601/08 , C07C2602/18 , C07C2603/74 , C07D207/16 , C07D209/52 , C07D277/04 , C07D295/185
摘要： Compounds are provided having the formula (I) wherein: n is 0, 1 or 2; m is 0, 1 or 2; the sum of n+m less then or equal to 2; the dashed bonds forming a cyclopropyl ring can only be present when Y is CH; X is H or CN; Y is CH, CH2, CHF, CF2, O, S, SO, or SO2; and A is adamantyl. Further provided are methods of using such compounds for the treatment of diabetes and related diseases, and to pharmaceutical compositions containing such compounds.
摘要翻译：提供具有式（I）的化合物，其中：n为0,1或2; m为0,1或2; n + m的和小于等于2; 当Y是CH时，形成环丙基环的虚线键只能存在; X是H或CN; Y是CH，CH 2 CH 2，CHF，CF 2 O，O，S，SO或SO 2。而A是金刚烷基。还提供了使用这些化合物治疗糖尿病和相关疾病的方法，以及含有这些化合物的药物组合物。

46. 发明申请

US20050197359A1 Bicyclic modulators of androgen receptor function 有权
标题翻译：雄激素受体功能的双环调节剂
公开(公告)号：US20050197359A1
公开(公告)日：2005-09-08
申请号：US11070808
申请日：2005-03-02
申请人： Alexandra Nirschl , James Sutton , Lawrence Hamann , Tammy Wang , Yan Zou , Chongqing Sun
发明人： Alexandra Nirschl , James Sutton , Lawrence Hamann , Tammy Wang , Yan Zou , Chongqing Sun
IPC分类号： A61K31/424 , A61K31/425 , A61K31/428 , A61K31/44 , A61K31/4745 , C07D263/60 , C07D471/02 , C07D491/02 , C07D498/02
CPC分类号： C07D487/04 , C07D498/04 , C07D513/04
摘要： The present invention relates to bicyclic compounds according to formula I, pharmaceutical compositions containing such compounds and methods of using such compounds in the treatment of androgen receptor-associated conditions, such as age-related diseases, for example sarcopenia, wherein R1, R2, R5, X, Y and n are defined herein.
摘要翻译：本发明涉及式I的双环化合物，含有这些化合物的药物组合物和使用这些化合物治疗雄激素受体相关病症例如年龄相关疾病，例如肌肉减少症的方法，其中R 1 R 2，R 5，X，Y和n在本文中定义。

47. 发明申请

US20050187267A1 Sulfonylpyrrolidine modulators of androgen receptor function and method 有权
公开(公告)号：US20050187267A1
公开(公告)日：2005-08-25
申请号：US11048439
申请日：2005-02-01
申请人： Lawrence Hamann , Yingzhi Bi , Mark Manfredi , Alexandra Nirschl , James Sutton
发明人： Lawrence Hamann , Yingzhi Bi , Mark Manfredi , Alexandra Nirschl , James Sutton
IPC分类号： A61K31/4015 , A61K31/433 , C07D207/48 , C07D285/06 , C07D285/14 , C07D498/04
CPC分类号： C07D285/14 , C07D207/48
摘要： Compounds are provided which are useful in the treatment of androgen receptor-associated conditions, such as age-related diseases, which compounds have the structure wherein R1 is hydrogen (H), alkyl or substituted alkyl, alkenyl or substituted alkenyl, arylalkyl or substituted arylalkyl, CO2R4a, CONR4aR4b, and CH2OR4a; R2 is hydrogen (H), OR3, SR3, halo, NHR3, NHCOR4c1, NHCO2R4c1, NHCONR4cR4d and NHSO2R4c; R3 in each functional group is hydrogen (H), alkyl or substituted alkyl, CHF2, CF3 and CON4e; R4, R4a, R4b, R4c, R4c1, R4d, R4e, R4f, R4g, or R4h in each functional group are the same or different and are hydrogen(H), alkyl or substituted alkyl, alkenyl or substituted alkenyl, alkynyl or substituted alkynyl, cycloalkyl or substituted cycloalkyl, arylalkyl or substituted arylalkyl, aryl or substituted aryl, or heteroaryl or substituted heteroaryl; R5 and R5′ are the same or different and are hydrogen(H), alkyl or substituted alkyl, alkenyl or substituted alkenyl, alkynyl or substituted alkynyl, cycloalkyl or substituted cycloalkyl, arylalkyl or substituted arylalkyl, aryl or substituted aryl, or heteroaryl or substituted heteroaryl, wherein at least one of R5 and R5′ is hydrogen, or R5 and R5′ taken together form a double bond with oxygen (O), sulfur (S), NR7 or CR7R7′; where R7 and R7′ are as defined herein; G is an aryl, heterocyclo or heteroaryl group, wherein said group is mono- or polycyclic, and which is optionally substituted; and n is an integer of 1 or 2, m is an integer of 1 or 2, Z is oxygen (—O—) or NR4h, a prodrug ester, all stereoisomers thereof and a pharmaceutically acceptable salt. A method for treating androgen receptor-associated conditions such as age-related diseases is also provided.

48. 发明申请

US20050081065A1 Method for securely delegating trusted platform module ownership 审中-公开
标题翻译：安全委托可信平台模块所有权的方法
公开(公告)号：US20050081065A1
公开(公告)日：2005-04-14
申请号：US10686343
申请日：2003-10-14
申请人： Ernie Brickell , David Grawrock , James Sutton
发明人： Ernie Brickell , David Grawrock , James Sutton
IPC分类号： G06F21/00 , H04L9/32
CPC分类号： G06F21/53 , G06F21/57
摘要： Managing authorization tokens within a computer system may be accomplished by creating a master owner token indicating full ownership of a resource within the computer system by a management environment, creating at least one delegate owner token for a environment, communicating the delegate owner token to the environment and to the resource, and allowing access to the resource by the environment when the environment presents a valid delegate owner token to the resource. In one embodiment, the resource comprises a trusted platform module (TPM).
摘要翻译：管理计算机系统中的授权令牌可以通过创建主管理器令牌来实现，该主人拥有者标记由管理环境指示计算机系统内的资源的完全所有权，为环境创建至少一个委托所有者令牌，将委托所有者令牌传达给环境和资源，并且当环境向资源呈现有效的代理所有者令牌时，允许环境访问资源。在一个实施例中，资源包括可信平台模块（TPM）。

49. 发明申请

US20100010217A1 METHODS FOR THE PREPARATION OF IMIDAZOLE-CONTAINING COMPOUNDS 审中-公开
标题翻译：制备含咪唑化合物的方法
公开(公告)号：US20100010217A1
公开(公告)日：2010-01-14
申请号：US12294225
申请日：2007-03-23
申请人： Nicholas M. Valiante , James Sutton , Jiong Lan
发明人： Nicholas M. Valiante , James Sutton , Jiong Lan
IPC分类号： C07D473/32 , C07D471/14 , C07D471/02 , C07D215/02 , C07D233/88
CPC分类号： C07D471/04
摘要： The present invention generally relates to methods for the preparation of compounds that contain imidazole moieties. In some embodiments, the methods include the reaction of a diamine with a dichloroimmonium compound to produce the imidazole moiety. In some embodiments, the methods are employed to prepare compounds having the Formulas II, II or III below: I II III wherein the constituent variables are as described herein.
摘要翻译：本发明一般涉及制备含有咪唑部分的化合物的方法。在一些实施方案中，所述方法包括二胺与二氯嘧啶化合物的反应以产生咪唑部分。在一些实施方案中，所述方法用于制备下面具有式II，II或III的化合物：I II III，其中组成变量如本文所述。

50. 发明申请

US20080108649A1 BICYCLIC MODULATORS OF ANDROGEN RECEPTOR FUNCTION 有权
标题翻译：雄激素受体功能的双相调制剂
公开(公告)号：US20080108649A1
公开(公告)日：2008-05-08
申请号：US11931282
申请日：2007-10-31
申请人： Chong-Qing Sun , Lawrence Hamann , David Augeri , Yingzhi Bi , Jeffrey Robl , Yan-Ting Huang , Tammy Wang , Alexandra Holubec , Ligaya Simpkins , James Sutton , James Li
发明人： Chong-Qing Sun , Lawrence Hamann , David Augeri , Yingzhi Bi , Jeffrey Robl , Yan-Ting Huang , Tammy Wang , Alexandra Holubec , Ligaya Simpkins , James Sutton , James Li
IPC分类号： A61K31/4545 , A61K31/4164 , A61K31/47 , A61P21/00 , C07D217/00 , C07D235/00 , C07D471/02
CPC分类号： C07D487/04 , C07D471/04
摘要： There are provided compounds according to formula I wherein the substitutents are as described herein. Further provided are methods of using such compounds for the treatment of nuclear hormone receptor-associated conditions, such as age related diseases, for example sarcopenia. Also provided are pharmaceutical compositions containing such compounds and processes for preparing some of the compounds of the invention. Other embodiments are also disclosed.
摘要翻译：提供根据式I的化合物，其中取代基如本文所述。进一步提供的是使用这些化合物来治疗核激素受体相关病症的方法，例如年龄相关疾病，例如肌肉减少症。还提供了含有这些化合物的药物组合物和制备本发明的一些化合物的方法。还公开了其他实施例。

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