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41. 发明申请

US20120172967A1 EMBOLIC PROTECTION SYSTEMS FOR BIFURCATED CONDUITS 有权
标题翻译：用于混凝土浇注的嵌入式保护系统
公开(公告)号：US20120172967A1
公开(公告)日：2012-07-05
申请号：US13413996
申请日：2012-03-07
申请人： Lixiao Wang , Martin Chambers
发明人： Lixiao Wang , Martin Chambers
IPC分类号： A61F2/84
CPC分类号： A61M25/104 , A61B17/1204 , A61F2/958 , A61F2/966
摘要： An apparatus for removing emboli from a vessel during an interventional procedure comprising a catheter. The catheter includes: an elongate member having a lumen extending from the proximal end to the distal end; a dilation element disposed on a distal portion of the elongate member, the dilation element having a contracted state and an expanded state; an occlusion element disposed on a distal portion of the elongate member, the occlusion element being disposed proximal of the dilation element, and the occlusion element having a contracted state and an expanded state; and one or more aspiration ports disposed on a distal portion of the elongate member, the one or more aspiration ports being in fluid communication with the lumen, and one or more of the aspiration ports being disposed proximal of the dilation element and distal of the occlusion element.
摘要翻译：一种用于在包括导管的介入手术过程中从血管中去除栓塞的装置。导管包括：细长构件，其具有从近端延伸到远端的内腔; 设置在细长构件的远端部分上的扩张元件，膨胀元件具有收缩状态和膨胀状态; 设置在所述细长构件的远侧部分上的遮挡元件，所述遮挡元件设置在所述扩张元件的近侧，所述遮挡元件具有收缩状态和膨胀状态; 以及设置在所述细长构件的远侧部分上的一个或多个抽吸口，所述一个或多个抽吸口与所述内腔流体连通，并且一个或多个吸入口设置在所述扩张元件的近侧和所述闭塞的远侧元件。

42. 发明授权

US07854743B2 Catheter for the delivery of therapeutic agents to tissues 有权
标题翻译：用于将治疗剂递送至组织的导管
公开(公告)号：US07854743B2
公开(公告)日：2010-12-21
申请号：US11185801
申请日：2005-07-21
申请人： Maria Palasis , James J. Barry , Louis Ellis , Gary L. Hendrickson , Kent D. Harrison , Lixiao Wang
发明人： Maria Palasis , James J. Barry , Louis Ellis , Gary L. Hendrickson , Kent D. Harrison , Lixiao Wang
IPC分类号： A61B17/32
CPC分类号： A61B17/3468 , A61B17/3478 , A61B90/39 , A61B2017/00247 , A61B2017/320084 , A61B2018/00392 , A61B2018/1425 , A61F2/2493 , A61L29/16 , A61L2300/258 , A61L2300/414 , A61L2300/64 , A61M25/0084 , A61M37/0069 , A61M2025/0004 , A61M2025/0089
摘要： A catheter for placement of an in situ implant is provided. This catheter may include a first elongate shaft having a proximal end and a distal end, a second elongate shaft having a proximal end and a distal end, a first sharpened distal tip disposed at the distal end of the first shaft and a second sharpened distal tip disposed at the distal end of the second shaft. The first shaft and the second shaft may also be secured to one another at the distal end of the first shaft according to the invention. Still further, according to other teachings, the first sharpened distal tip may extend beyond the second sharpened distal tip in a catheter that practices the invention.
摘要翻译：提供了用于放置原位植入物的导管。该导管可以包括具有近端和远端的第一细长轴，具有近端和远端的第二细长轴，设置在第一轴的远端处的第一尖锐的远侧末端和第二尖锐远端设置在第二轴的远端。根据本发明，第一轴和第二轴也可以在第一轴的远端处彼此固定。此外，根据其他教导，第一锐化的远侧末端可以在实践本发明的导管中延伸超过第二锋利的远侧末端。

43. 发明授权

US07632302B2 Stent and stent delivery system for ostial locations in a conduit 有权
标题翻译：支架和支架输送系统用于导管中的位置
公开(公告)号：US07632302B2
公开(公告)日：2009-12-15
申请号：US11559455
申请日：2006-11-14
申请人： Daniel J. Vreeman , Joshua Evans Berman , Richard Kusleika , Steve Gene Zaver , Lixiao Wang
发明人： Daniel J. Vreeman , Joshua Evans Berman , Richard Kusleika , Steve Gene Zaver , Lixiao Wang
IPC分类号： A61F2/06
CPC分类号： A61F2/958 , A61F2/915 , A61F2/962 , A61F2002/821 , A61F2002/91508 , A61F2002/91525 , A61F2002/91541 , A61F2002/91558 , A61F2220/005 , A61F2220/0058 , A61F2230/0013 , A61F2250/0048
摘要： A renal stent includes a balloon expandable segment intended for deployment in the renal vessel and a self expanding segment intended for deployment in the aortic segment. One or both of the balloon expandable and self expanding segments can be deployed in the ostial region of the renal vessel, typically the renal artery. The balloon expandable segment provides superior radial strength for maintaining dilated diameter of the renal vessel. The self expanding segment expands to conform to the flared ostial and aortic regions of the vessel. The self expanding segment can be balloon dilated to enhance conformance of the self expanding stented segment to the ostial and aortic regions.
摘要翻译：肾支架包括用于部署在肾容器中的球囊可扩张部分和用于部署在主动脉部分中的自扩张部分。球囊扩张和自扩张部分中的一个或两个可以部署在肾血管的口部区域，通常是肾动脉。球囊可扩张部分提供优越的径向强度以保持肾血管的扩张直径。自扩张部分扩张以符合血管的扩张的口腔和主动脉瓣区域。自膨胀部分可以球囊扩张，以增强自扩张支架段与口腔和主动脉区域的一致性。

44. 发明授权

US07541077B2 Medical device components 有权
标题翻译：医疗器械部件
公开(公告)号：US07541077B2
公开(公告)日：2009-06-02
申请号：US11929208
申请日：2007-10-30
申请人： Victor Schoenle , Daniel James Horn , Yiqun Wang , Lixiao Wang
发明人： Victor Schoenle , Daniel James Horn , Yiqun Wang , Lixiao Wang
IPC分类号： B32B1/08 , F16L11/04 , F16L11/20 , A61M29/02 , A61M39/00
CPC分类号： A61M25/1036 , A61M25/0045 , A61M25/10 , A61M25/1006 , A61M2025/018 , Y10T29/49826 , Y10T29/49863 , Y10T29/49865 , Y10T428/13 , Y10T428/1334 , Y10T428/1345 , Y10T428/1352 , Y10T428/139 , Y10T428/1393
摘要： Medical device components, such as tube-shaped catheter components, are disclosed. In some embodiments, a medical device component includes a region that includes a polyamide having a post buckle fracture tensile strength of at least about 6500 psi.
摘要翻译：公开了医疗装置部件，例如管状导管部件。在一些实施例中，医疗装置部件包括包括具有至少约6500psi的后扣环断裂拉伸强度的聚酰胺的区域。

45. 发明申请

US20080175887A1 Treatment of Asthma and Chronic Obstructive Pulmonary Disease With Anti-proliferate and Anti-inflammatory Drugs 审中-公开
标题翻译：用抗增生和抗炎药物治疗哮喘和慢性阻塞性肺疾病
公开(公告)号：US20080175887A1
公开(公告)日：2008-07-24
申请号：US11942459
申请日：2007-11-19
申请人： Lixiao Wang
发明人： Lixiao Wang
IPC分类号： A61K9/12 , A61K31/436 , A61P11/00 , A61M15/00 , A61F2/82 , A61M25/10 , A61M11/00 , A61K31/337
CPC分类号： A61L29/16 , A61K31/337 , A61K31/436 , A61K45/06 , A61L29/08 , A61L29/085 , A61L29/18 , A61L31/16 , A61L31/18 , A61L2300/216 , A61L2300/416 , A61L2300/428 , A61L2300/608 , A61L2300/802 , A61L2420/06 , A61L2420/08 , A61M25/10 , A61M2025/105 , A61M2210/1025 , A61K2300/00
摘要： Embodiments of the present invention provide a method for treatment of respiratory disorders such as asthma, chronic obstructive pulmonary disease, and chronic sinusitis, including cystic fibrosis, interstitial fibrosis, chronic bronchitis, emphysema, bronchopulmonary dysplasia and neoplasia. The method involves administration, preferably oral, nasal or pulmonary administration, of anti-inflammatory and anti-proliferative drugs (rapamycin or paclitaxel and their analogues).
摘要翻译：本发明的实施方案提供了一种治疗呼吸系统疾病如哮喘，慢性阻塞性肺病和慢性鼻窦炎的方法，包括囊性纤维化，间质性纤维化，慢性支气管炎，肺气肿，支气管肺发育不良和瘤形成。该方法包括施用抗炎和抗增殖药物（雷帕霉素或紫杉醇及其类似物），优选口服，鼻或肺给药。

46. 发明授权

US07279002B2 Cutting stent and balloon 失效
标题翻译：切割支架和气球
公开(公告)号：US07279002B2
公开(公告)日：2007-10-09
申请号：US10423598
申请日：2003-04-25
申请人： William J. Shaw , Eric B. Stenzel , Lixiao Wang
发明人： William J. Shaw , Eric B. Stenzel , Lixiao Wang
IPC分类号： A61F2/06 , A61M29/00
CPC分类号： A61B17/320725 , A61B17/22 , A61B2017/00831 , A61B2017/22051 , A61F2/958 , A61F2250/0028 , A61L29/126 , A61M25/10
摘要： A stent or sheath having one or more cutting blades may be constructed for implantation in the body. A balloon having one or more cutting blades may be used with a stent or a sheath.
摘要翻译：具有一个或多个切割刀片的支架或护套可被构造用于植入体内。具有一个或多个切割刀片的气囊可以与支架或护套一起使用。

47. 发明申请

US20060259120A1 Implant delivery system with interlocked RX port orientation 有权
公开(公告)号：US20060259120A1
公开(公告)日：2006-11-16
申请号：US11433328
申请日：2006-05-12
申请人： Khamla Vongphakdy , Huisun Wang , Adel Hashw , Lixiao Wang
发明人： Khamla Vongphakdy , Huisun Wang , Adel Hashw , Lixiao Wang
IPC分类号： A61F2/06
CPC分类号： A61M25/09 , A61F2/95 , A61F2/966 , A61F2002/9505 , A61F2002/9583 , A61F2002/9665 , Y10T29/49938
摘要： A medical implant delivery system maintains an orientation between a guidewire lumen of an inner member of the system and a rapid-exchange port in an outer member. The medical device is disposed intermediate the inner and outer members and in friction or pressure-fit contact with the outer member. Once the guidewire lumen of the inner member and the rapid exchange port of the outer member are oriented, the friction or pressure-fit operates to maintain the orientation until deployment of the medical implant. Orientation is further maintained by a telescoping coupling of the guide wire lumen with the rapid exchange port.

48. 发明授权

US07101597B2 Medical devices made from polymer blends containing low melting temperature liquid crystal polymers 有权
公开(公告)号：US07101597B2
公开(公告)日：2006-09-05
申请号：US10012872
申请日：2001-12-12
申请人： Lixiao Wang , Jianhua Chen
发明人： Lixiao Wang , Jianhua Chen
IPC分类号： B29D22/02 , B29D23/00
CPC分类号： A61M25/0009 , A61F2/958 , A61L29/049 , A61L29/14 , A61M25/1029 , A61M2025/1084 , Y10T428/1334 , Y10T428/1341 , Y10T428/1352 , Y10T428/1372 , Y10T428/139
摘要： A medical device, at least a portion of which is composed of a polymeric material in which the polymeric material is a melt blend product of at least two different thermoplastic polymers, one of the thermoplastic polymers being a thermoplastic liquid crystal polymer (LCP) having a melting point of less than 250° C. The portion of the device made from the melt blend may be a catheter body segment or a balloon for a catheter. The LCP blends suitably also include a non-LCP base polymer having a melting point in the range of about 140° C. to about 265° C.

49. 发明申请

US20060161240A1 Catheter for controlled stent delivery 审中-公开
公开(公告)号：US20060161240A1
公开(公告)日：2006-07-20
申请号：US11356368
申请日：2006-02-16
申请人： Lixiao Wang
发明人： Lixiao Wang
IPC分类号： A61F2/06
CPC分类号： A61F2/958 , A61F2002/9583 , A61F2250/0039 , A61M25/1002 , A61M29/02 , A61M2025/1059
摘要： A catheter having a catheter shaft and a medical balloon mounted thereon. The medical balloon having a non-inflated state and being inflatable to an inflated state. The medical balloon having a stent mounting region, with a stent being disposed about at least a portion of the stent mounting region. The stent mounting region having a middle portion, a first end portion adjacent to the middle portion and a second end portion adjacent to the middle portion. The middle portion having a middle portion diameter, the first end portion having a first end portion diameter, the second end portion having a second end portion diameter. In the non-inflated state the middle portion diameter being different from the first end portion diameter and the second end portion diameter, in the inflated state the middle portion diameter being substantially the same as the fist end portion diameter and the second end portion diameter.

50. 发明申请

US20060151921A1 Medical device balloons with improved strength properties and processes for producing the same 审中-公开
标题翻译：具有改善的强度特性的医疗装置气球及其制造方法
公开(公告)号：US20060151921A1
公开(公告)日：2006-07-13
申请号：US11356522
申请日：2006-02-17
申请人： Lixiao Wang , John Chen , Jeffrey Lindquist , Nao Lee , Douglas Devens
发明人： Lixiao Wang , John Chen , Jeffrey Lindquist , Nao Lee , Douglas Devens
IPC分类号： H05B6/00
CPC分类号： A61L31/06 , A61L31/125 , A61M25/1029 , B29C48/022 , B29C48/09 , B29C48/832 , B29C48/86 , B29C48/865 , B29C48/919 , B29L2031/7542 , Y10T428/1086
摘要： A tubular parison for forming a medical device balloon. The parison is formed of a polymeric material, for instance a thermoplastic elastomer. The parison has an elongation at break which is not more than 80% of the elongation of the bulk polymeric material. The elongation of the parison is controlled by altering extrusion conditions. Balloons prepared from the parisons provide higher wall strength and/or higher inflation durability than balloons prepared from conventional parisons of the same material.
摘要翻译：一种用于形成医疗装置气囊的管形型坯。型坯由聚合物材料形成，例如热塑性弹性体。型坯的断裂伸长率不大于本体聚合材料的伸长率的80％。通过改变挤出条件来控制型坯的伸长率。从型坯制备的气球比从相同材料的常规型坯制备的气球提供更高的壁强度和/或更高的充气耐久性。

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