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41. 发明授权

US08876176B2 Latch assembly 有权
标题翻译：锁定装配
公开(公告)号：US08876176B2
公开(公告)日：2014-11-04
申请号：US11816445
申请日：2006-02-17
申请人： Nigel V. Spurr , Gurbinder Singh Kalsi , Chris Rhodes , Robert Frank Tolley , David Peatey , Robert James Clawley , Paul Moore , Jean-Vincent Olivier , Sylvain Remi Chonavel , Denis Cavallucci
发明人： Nigel V. Spurr , Gurbinder Singh Kalsi , Chris Rhodes , Robert Frank Tolley , David Peatey , Robert James Clawley , Paul Moore , Jean-Vincent Olivier , Sylvain Remi Chonavel , Denis Cavallucci
IPC分类号： E05C3/06 , E05B81/20 , E05B81/14 , E05C3/16 , E05B77/28 , E05B85/26
CPC分类号： E05C3/12 , E05B77/28 , E05B81/14 , E05B81/20 , E05B85/26 , E05C3/006 , Y10S292/23 , Y10T70/5903 , Y10T70/70 , Y10T292/1047 , Y10T292/1082
摘要： A latch assembly includes a chassis, a latch bolt moveably mounted on the chassis and having a closed position for retaining a striker and an open position for releasing the striker, a pawl having an engaged position at which the pawl is engaged with the latch bolt to hold the latch bolt in the closed position and a disengaged position at which the pawl is disengaged from the latch bolt, thereby allowing the latch bolt to move to the open position, an eccentric arrangement defining an eccentric axis and a pawl axis remote from the eccentric axis. The eccentric arrangement is rotatable about the eccentric axis, and the pawl is rotatable about the pawl axis. When the pawl moves from the engaged position to the disengaged position, the eccentric arrangement rotates in one of a clockwise and a counter-clockwise direction about the eccentric axis. With the pawl in the engaged position, a force applied to the pawl by the latch bolt creates a turning moment on the eccentric arrangement in the one of the clockwise and counter-clockwise direction, and the eccentric arrangement is prevented from rotating in said one of the clockwise and counter-clockwise direction by a moveable abutment.
摘要翻译：闩锁组件包括底盘，可移动地安装在底盘上并具有用于保持撞针的关闭位置和用于释放撞针的打开位置的闩锁;棘爪，其具有接合位置，棘爪与闩锁螺栓接合将闩锁螺栓保持在关闭位置和棘爪从闩锁螺栓脱离的分离位置，从而允许闩锁闩锁移动到打开位置，限定偏心轴线的偏心装置和远离偏心轮的爪轴线轴。偏心装置可围绕偏心轴线旋转，并且棘爪可围绕棘爪轴线转动。当棘爪从接合位置移动到脱离位置时，偏心装置围绕偏心轴线以顺时针和逆时针方向中的一个旋转。在棘爪处于接合位置时，通过闩锁螺栓施加到棘爪的力在顺时针和逆时针方向上的偏心装置上产生转动力矩，并且防止偏心装置在所述一个顺时针方向和逆时针方向可移动的支座。

42. 发明授权

US08524238B2 Cancer targets and uses thereof 有权
标题翻译：癌症目标及其用途
公开(公告)号：US08524238B2
公开(公告)日：2013-09-03
申请号：US13436411
申请日：2012-03-30
申请人： Dong Fang , Paul Moore , Steve Ruben , Sudeepta Aggarwal
发明人： Dong Fang , Paul Moore , Steve Ruben , Sudeepta Aggarwal
IPC分类号： A61K39/395 , A61K39/00
CPC分类号： C07K16/249 , A61K39/39533 , A61K2039/505 , C07K14/47 , C07K14/57 , C07K16/18 , C07K16/30 , C07K2317/21 , C07K2317/24 , C07K2317/54 , C07K2317/55 , C07K2317/622 , C07K2317/732 , C07K2317/734 , C12N15/113 , C12N2310/14 , C12Q1/6886 , C12Q2600/106 , C12Q2600/118 , C12Q2600/158 , G01N33/5011 , G01N33/574 , G01N33/57484 , G01N2500/10
摘要： Methods and compositions are provided for assessing, treating, and preventing diseases, especially cancer, using cancer-associated targets (“CAT”). Methods and compositions are also provided for determining or predicting the effectiveness of a treatment for these diseases or for selecting a treatment, using CAT. Methods and compositions are further provided for modulating cell function using CAT. Also provided are compositions that modulate CAT (e.g., antagonists or agonists), such as antibodies, proteins, small molecule compounds, and nucleic acid agents (e.g., RNAi and antisense agents), as well as pharmaceutical compositions thereof. Further provided are methods of screening for agents that modulate CAT, and agents identified by these screening methods.
摘要翻译：提供了使用癌症相关靶标（“CAT”）评估，治疗和预防疾病，特别是癌症的方法和组合物。还提供了用于确定或预测这些疾病的治疗或使用CAT选择治疗的有效性的方法和组合物。还提供了使用CAT调节细胞功能的方法和组合物。还提供了调节CAT（例如拮抗剂或激动剂）如抗体，蛋白质，小分子化合物和核酸试剂（例如RNAi和反义试剂）的组合物及其药物组合物。进一步提供了筛选调节CAT的试剂的方法，以及通过这些筛选方法鉴定的试剂。

43. 发明申请

US20120273446A1 DENTAL BUR STORAGE DEVICE 有权
标题翻译：牙科仓储设备
公开(公告)号：US20120273446A1
公开(公告)日：2012-11-01
申请号：US13504568
申请日：2010-10-29
申请人： Paul Moore
发明人： Paul Moore
IPC分类号： A61C3/04
CPC分类号： A61C3/04 , A47F7/0028 , A61G15/16
摘要： The present invention is directed towards a dental bur storage device having a plurality of dental bur receiving holes capable of retaining a plurality of different dental bur types having different shank diameters, wherein, each of the plurality of dental bur receiving holes is tapered to allow a retaining fit to be established with any one of the plurality of different dental bur types having different shank diameters. The advantage of using a receiving hole that has a tapered form is that different types of dental burs having different diameters of shanks may be retained by the receiving holes in the dental bur storage device. This allows a wide range of different brands and different types of dental burs to be accommodated on one single dental bur storage device which greatly simplifies the process of selecting a dental bur for a dentist, particularly during a dental treatment. As the receiving hole is tapered, bur shanks of varying dimensions will be received to different depths within the receiving hole to a point where the receiving hole tapers to a diameter substantially equal to the diameter of the shank of the dental bur being received. Moreover, using this type of receiving hole, positive retention of a dental bur may be achieved when the dental bur storage device is handled roughly or inverted.
摘要翻译：本发明涉及具有能够保持具有不同柄直径的多种不同牙钻类型的多个牙钻接收孔的牙科钻头储存装置，其中，多个牙钻接收孔中的每一个都是锥形的，以允许与具有不同柄直径的多种不同牙钻类型中的任何一种形成保持配合。使用具有锥形形状的接收孔的优点是具有不同直径的柄的不同类型的牙钻可以通过牙科钻头储存装置中的接收孔保持。这允许在一个单一的牙科保存装置上容纳各种不同品牌和不同类型的牙钻，这大大简化了牙科医生选择牙科钻头的过程，特别是在牙科治疗期间。当接收孔是锥形时，不同尺寸的螺栓柄将被容纳在接收孔内的不同深度处，以至于接收孔逐渐变细到基本上等于所接收的牙科钻头的直径的直径。此外，当使用这种类型的接收孔时，可以在牙科钻头存储装置被粗略地或倒置地处理时实现牙科钻头的正保持。

44. 发明申请

US20110086920A1 Gamma Glutamylcysteine Treatment or Prevention of Oxidative Injury 审中-公开
标题翻译： γ-谷氨酰半胱氨酸治疗或预防氧化损伤
公开(公告)号：US20110086920A1
公开(公告)日：2011-04-14
申请号：US12747786
申请日：2008-12-11
申请人： Marshall Summar , Gary Cunningham , Michael Aschner , Truc Le , Rick Barr , Paul Moore
发明人： Marshall Summar , Gary Cunningham , Michael Aschner , Truc Le , Rick Barr , Paul Moore
IPC分类号： A61K31/198 , C12N5/071 , C12N5/077 , A61P39/06
CPC分类号： A61K38/05
摘要： The present invention concerns the γ-glutamylcysteine treatment to reduce oxidative damage caused by ischemia/reperfusion events such as pulmonary hypertension, transplant, cardiac bypass and other surgeries, and trauma. In specific embodiments, preservation methods and apparatuses for preserving tissue for transplantation purposes is provided.
摘要翻译：本发明涉及γ-谷氨酰半胱氨酸治疗以减少由缺血/再灌注事件（例如肺动脉高压，移植，心脏旁路和其他手术）和创伤引起的氧化损伤。在具体实施方案中，提供了用于保持用于移植的组织的保存方法和装置。

45. 发明申请

US20070257496A1 Latch assembly 审中-公开
标题翻译：锁定装配
公开(公告)号：US20070257496A1
公开(公告)日：2007-11-08
申请号：US11707659
申请日：2007-02-16
申请人： Nigel Spurr , Denis Cavallucci , Gurbinder Kalsi , Chris Rhodes , Sylvain Chonavel , David Peatey , Paul Moore , Robert Tolley , Jean-Vincent Olivier , Robert Clawley
发明人： Nigel Spurr , Denis Cavallucci , Gurbinder Kalsi , Chris Rhodes , Sylvain Chonavel , David Peatey , Paul Moore , Robert Tolley , Jean-Vincent Olivier , Robert Clawley
IPC分类号： E05C5/02
CPC分类号： E05B17/0037 , E05B81/14 , E05B85/26 , Y10T292/0863
摘要： A latch assembly includes a chassis and a rotatable claw-type latch bolt moveably mounted on the chassis. The latch bolt has a closed position for retaining a striker and an open position for releasing the striker. The latch bolt is provided with a latch abutment remote from a center of rotation. The latch assembly further includes a pawl rotatable about a pawl axis and having an engaged position for holding the latch bolt in the closed position and a disengaged position that allows the latch bolt to move to the open position. The latch assembly includes an eccentric arrangement defining a first axis and the pawl axis remote from the first axis. The latch assembly also includes a reset lever rotatably fixed to the eccentric arrangement for mutual rotation with the eccentric arrangement about the first axis. The latch assembly includes a biasing lever configured to transmit a biasing force to the reset lever at a position remote from the first axis and to the latch bolt via the latch abutment. The latch assembly includes a biasing device arranged to apply the biasing force to the biasing lever. The latch assembly is configured such that when the pawl retains the latch bolt in the closed position, the biasing lever applies a force to the reset lever to promote disengagement of the pawl, and such that when the pawl is disengaged, the biasing lever promotes the rotation of the latch bolt into the open position.
摘要翻译：闩锁组件包括底盘和可移动地安装在底盘上的可旋转爪型闩锁螺栓。闩锁螺栓具有用于保持撞针的关闭位置和用于释放撞针的打开位置。闩锁螺栓设置有远离旋转中心的闩锁支座。闩锁组件还包括可围绕棘爪轴线旋转并且具有用于将闩锁闩锁保持在关闭位置的接合位置的棘爪和允许闩锁闩锁移动到打开位置的脱离位置。闩锁组件包括限定第一轴线的偏心装置和远离第一轴线的棘爪轴线。闩锁组件还包括可旋转地固定到偏心装置的复位杆，用于使偏心装置围绕第一轴线相互旋转。闩锁组件包括偏置杆，所述偏压杆构造成在远离第一轴线的位置处将偏置力传递到复位杆，并且经由闩锁邻接件传递到闩锁螺栓。闩锁组件包括偏置装置，其被布置成将偏置力施加到偏置杆。闩锁组件被构造成使得当棘爪将闩锁闩锁保持在关闭位置时，偏置杆向复位杆施加力以促使棘爪脱离，并且使得当棘爪脱离时，偏置杆促使闩锁螺栓旋转到打开位置。

46. 发明申请

US20060226661A1 Power closure latch assembly 审中-公开
标题翻译：电动闭合闩锁组件
公开(公告)号：US20060226661A1
公开(公告)日：2006-10-12
申请号：US11389520
申请日：2006-03-24
申请人： Paul Moore
发明人： Paul Moore
IPC分类号： E05C3/06
CPC分类号： E05B81/20 , E05B47/0012 , E05B81/46 , E05B81/90 , E05B2047/0017 , E05B2047/0026 , Y10T292/1047
摘要： A latch assembly includes a latch bolt for engaging an associated striker. The latch bolt has an open position, a safety position and a closed position, which positions correspond to an open condition, a safety condition and closed condition, respectively, in the latch assembly. The latch assembly further includes a pawl for releasably retaining the latch bolt in the safety position and the closed position. The latch assembly includes a power closure mechanism that applies a drive load to the latch bolt to drive the latch bolt from the safety position to the closed position and a pivotably mounted driving member with a first portion which in use abuts against the latch bolt in response to powered closure. The powered closure results from movement of the pivot of the driving member combined with abutment of a second portion of the driving member against a bearing surface.
摘要翻译：闩锁组件包括用于接合相关联的撞针的闩锁螺栓。闩锁螺栓具有分别对应于闩锁组件中的打开状态，安全状态和关闭状态的打开位置，安全位置和关闭位置。闩锁组件还包括用于将闩锁螺栓可释放地保持在安全位置和关闭位置的棘爪。闩锁组件包括动力闭合机构，其将驱动负载施加到闩锁螺栓以将闩锁螺栓从安全位置驱动到关闭位置，并且枢转地安装的驱动构件具有第一部分，第一部分在使用中抵靠闩锁螺栓响应动力关闭。动力闭合由驱动构件的枢轴的运动与驱动构件的第二部分抵靠支承表面相结合而组合。

47. 发明申请

US20060129570A1 Method and apparatus for maintaining multiple sets of identity data 有权
标题翻译：用于维护多组身份数据的方法和装置
公开(公告)号：US20060129570A1
公开(公告)日：2006-06-15
申请号：US11009921
申请日：2004-12-10
申请人： Paul Moore
发明人： Paul Moore
IPC分类号： G06F7/00
CPC分类号： H04L61/1523 , G06F21/31 , G06F2221/2117 , G06F2221/2149 , H04L63/104
摘要： A method of assigning the UNIX computers in a network to one of a plurality of groups called zones, of creating independent sets of UNIX identity information for each network entity (user or group) for separate zones, and of associating an entity's sets of UNIX entity information with a single global entity record for the entity in the network's identity resolver. A further method of allowing a UNIX computer to request entity information from the identity resolver, and of the identity resolver returning resolved entity information appropriate for the requesting computer's zone. A further method of managing sets of zone-specific UNIX identity information in the identity resolver to ensure that entity names and entity identification numbers are not duplicated within a zone and to all the same names and numbers to be duplicated across zones. Other embodiments are also described.
摘要翻译：将网络中的UNIX计算机分配给称为区域的多个组之一的方法，为用于单独区域的每个网络实体（用户或组）创建独立的UNIX身份信息集合，以及将实体的UNIX实体集合信息与网络身份解析器中的实体具有单个全局实体记录。允许UNIX计算机从身份解析器请求实体信息以及身份解析器返回适合于请求计算机区域的解析实体信息的另一种方法。在身份解析器中管理区域特定的UNIX身份信息集合的另一种方法，以确保实体名称和实体标识号不在区域内复制，并且跨区域复制所有相同的名称和数字。还描述了其它实施例。

48. 外观设计

USD430465S Garden rake head 失效
公开(公告)号：USD430465S
公开(公告)日：2000-09-05
申请号：US111537
申请日：1999-09-29
申请人： Paul Moore
设计人： Paul Moore

49. 发明授权

US5432559A Self-adjusting window circuit with timing control 失效
标题翻译：具有定时控制功能的自调整窗口电路
公开(公告)号：US5432559A
公开(公告)日：1995-07-11
申请号：US149258
申请日：1993-11-09
申请人： Bryan Bruins , Paul Moore
发明人： Bryan Bruins , Paul Moore
IPC分类号： H04N5/08 , H04N5/10
CPC分类号： H04N5/08
摘要： A self-adjusting window circuit suitable for fabrication as a monolithic integrated circuit. The self-adjusting window circuit comprises an input port, a positive edge detector coupled to the input port, a latch coupled to the output of the edge detector and a charging stage coupled to the latch. The input signal comprises a signal having a sequence of pulses appearing at a predetermined scan rate, for example, a composite video signal. The input port feeds the input signal to the edge detector which produces a pulse output signal in response to detecting a pulse in the input signal. The pulse output from the edge detector is latched and used to generate a charging control signal which controls the charging stage. In response to the charging control signal, the charging stage produces a window control signal for a predetermined period. The circuit includes a feedback network which injects the window control signal into the positive edge detector so that the positive edge detector is disabled while the window control signal is active.
摘要翻译：一种适合制造为单片集成电路的自调整窗口电路。自调整窗口电路包括输入端口，耦合到输入端口的上升沿检测器，耦合到边缘检测器的输出端的锁存器和耦合到锁存器的充电级。输入信号包括具有以预定扫描速率出现的脉冲序列的信号，例如复合视频信号。输入端口将输入信号馈送到边缘检测器，其响应于检测到输入信号中的脉冲而产生脉冲输出信号。来自边缘检测器的脉冲输出被锁存并用于产生控制充电阶段的充电控制信号。响应于充电控制信号，充电阶段产生预定时段的窗口控制信号。电路包括反馈网络，其将窗口控制信号注入到上升沿检测器中，使得边沿检测器在窗口控制信号有效时被禁止。

50. 发明申请

US20210276032A1 Irrigation Stand Assembly 有权
公开(公告)号：US20210276032A1
公开(公告)日：2021-09-09
申请号：US16808000
申请日：2020-03-03
申请人： Paul Moore
发明人： Paul Moore
IPC分类号： B05B15/625 , B05B15/628 , B05B15/63
摘要： An irrigation stand assembly for hands free irrigation includes a handle has a first portion slidably engaging a second portion such that the handle has a telescopically adjustable length. A spray nozzle is coupled to the handle and the spray nozzle has an input and an output. The input is fluidly attachable to a fluid source to receive a fluid and the output sprays the fluid for irrigation. A stand is vertically orientable on a support surface and the stand releasably engages the handle for retaining the handle in an upright position. In this way the spray nozzle can be positioned on the support surface to irrigate the support surface without requiring the user to bend over.

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