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41. 发明授权

US10858312B1 Gossypol isocyanate ester compounds with antileukemic activities and a method of preparing the same 有权
公开(公告)号：US10858312B1
公开(公告)日：2020-12-08
申请号：US16939766
申请日：2020-07-27
申请人： Xiaolin Xie , Dezhu Zhang , Zhong Meng , Jianguo Meng , Yu Wang , Shunjun Ding , Chengyuan Liang , Liang Xin , Jingyi Li , Jiayun Zhang , Kangxiong Wu , Juan Xia , Han Li
发明人： Xiaolin Xie , Dezhu Zhang , Zhong Meng , Jianguo Meng , Yu Wang , Shunjun Ding , Chengyuan Liang , Liang Xin , Jingyi Li , Jiayun Zhang , Kangxiong Wu , Juan Xia , Han Li
IPC分类号： C07C271/02 , C07C269/06
摘要： A compound of Formula I: is disclosed. A method of preparing the compound of Formula I is also disclosed. R is alkyl, haloalkyl, aryl, or substituted aryl. Preferably, R is —CH3, —CH2CH3, —CH2CH2CH3, —CH(CH3)2, —CH2CH2CH2CH3, —CF3, —CHF2, —CH2CF3,

42. 发明授权

US09555139B2 Binding ligand linked drug delivery conjugates of tubulysins 有权
标题翻译：肾上腺素的结合配体连接的药物递送共轭物
公开(公告)号：US09555139B2
公开(公告)日：2017-01-31
申请号：US12530952
申请日：2008-03-13
申请人： Iontcho Radoslavov Vlahov , Christopher Paul Leamon , Yu Wang
发明人： Iontcho Radoslavov Vlahov , Christopher Paul Leamon , Yu Wang
IPC分类号： A61K47/48 , A61K38/00 , A61K51/04
CPC分类号： C07K7/06 , A61K47/55 , A61K47/551 , A61K47/64 , A61K47/65 , A61K47/6811 , A61K51/0497 , C07K5/021 , C07K5/06078
摘要： Described herein are compounds, pharmaceutical compositions and methods for treating pathogenic cell populations. The compounds described herein include conjugates of tubulysins and vitamin receptor binding ligands. The conjugates also include a releasable bivalent linker.
摘要翻译：本文描述了用于治疗致病细胞群体的化合物，药物组合物和方法。本文所述的化合物包括管状蛋白和维生素受体结合配体的缀合物。缀合物还包括可释放的二价连接体。

43. 发明授权

US09528820B2 System and method for using a linear polarizer to reduce optical crosstalk for optical proximity sensors 有权
标题翻译：使用线性偏振器以减少光学接近传感器的光学串扰的系统和方法
公开(公告)号：US09528820B2
公开(公告)日：2016-12-27
申请号：US14124235
申请日：2012-06-06
申请人： Yu Wang , Kerry Glover , David Mehrl , Greg Stoltz , Tom Dunn
发明人： Yu Wang , Kerry Glover , David Mehrl , Greg Stoltz , Tom Dunn
IPC分类号： G01B11/14 , H03K17/94
CPC分类号： G01B11/14 , H03K17/941 , H03K2217/94108
摘要： An optical proximity sensor often emits light, and detects the photons in the returned light signal. Because light can be reflected and scattered by cover glass and ink layer printed on the cover glass, optical crosstalk is a concern for the optical proximity sensors. In one embodiment, the present disclosure provides an optical proximity sensor including a linear polarizer to cover the photo detector, or a polarizer to cover the light emitting device, or two polarizers to cover both the photo detector and the light emitting device. The polarizer blocks the s-polarized light and only allows the p-polarized light to pass through. Because the scattered light is predominated by the s-polarization, the optical crosstalk may be reduced.
摘要翻译：光学接近传感器经常发光，并检测返回的光信号中的光子。由于光可以通过盖玻片上印刷的玻璃和油墨层进行反射和散射，因此光学串扰是光学接近传感器的关键。在一个实施例中，本公开提供了一种光学接近传感器，其包括用于覆盖光电检测器的线性偏振器或覆盖发光器件的偏振器，或者两个偏振器以覆盖光电检测器和发光器件。偏振器阻挡s偏振光，并且仅允许p偏振光通过。由于散射光被s极化所主导，所以可能会降低光学串扰。

44. 发明授权

US09445335B2 Handover prediction using historical data 有权
标题翻译：使用历史数据进行切换预测
公开(公告)号：US09445335B2
公开(公告)日：2016-09-13
申请号：US14406941
申请日：2012-06-13
申请人： Jing Fu , Åsa Bertze , Icaro L. J. Da Silva , Fredrik Kuivinen , Yu Wang
发明人： Jing Fu , Åsa Bertze , Icaro L. J. Da Silva , Fredrik Kuivinen , Yu Wang
IPC分类号： H04W4/00 , H04W36/24 , H04J3/06 , H04W36/02 , H04W36/08 , H04W36/30
CPC分类号： H04W36/245 , H04J3/0632 , H04W36/023 , H04W36/08 , H04W36/30
摘要： A method in an apparatus 301 for adapting play out of data packets during a handover of a user equipment (UE) 302 between a first radio network node (RNN) 304 and a second RNN 306. The packets relate to a real-time service application. The UE, first and second RNNs are comprised in a communications system 300. The method comprises generating at least one message to an adaptation control module. The at least one message is generated based on collected historical handover information and on current handover information. The method comprises further, by means of the adaptation control module, adapting the adapting the play out of the packets in dependence of the at least one message such that radio quality degradation in the real-time service application is controlled.
摘要翻译：用于在第一无线电网络节点（RNN）304和第二RNN 306之间的用户设备（UE）302的切换期间适配数据分组播放的装置301中的方法。分组涉及实时业务应用。 UE，第一和第二RNN包括在通信系统300中。该方法包括向自适应控制模块生成至少一个消息。基于收集的历史切换信息和当前切换信息来生成至少一个消息。该方法进一步包括借助于自适应控制模块，根据该至少一个消息来适配从分组中播放的播放，从而控制实时业务应用中的无线质量恶化。

45. 发明授权

US09276328B2 Small-caliber, high-performance broadband radiator 有权
标题翻译：小口径，高性能宽带散热器
公开(公告)号：US09276328B2
公开(公告)日：2016-03-01
申请号：US14147873
申请日：2014-01-06
申请人： Peng Chen , Xiao-Liu Du , Yu Wang , Yan-Kui Su
发明人： Peng Chen , Xiao-Liu Du , Yu Wang , Yan-Kui Su
IPC分类号： H01Q21/26 , H01Q1/24 , H01Q21/08
CPC分类号： H01Q21/26 , H01Q1/246 , H01Q21/08
摘要： A small-caliber, high-performance broadband radiator allows two unit arms of the first and second group of dipoles to be folded inwards, an included angle of 40°-50° is formed between two unit arms of the first/second groups of dipoles and the first/second unit racks, and the unit arms of the first and second groups of dipoles are arranged linearly at interval while flexural loading sections are provided and also connected by dielectric medium. Hence, the broadband radiator allows significant reduction of the aperture of the broadband radiator, and there is a larger adjustment space for the gap of the radiator array, so the interference of low and high bands is less. This allows for improved performance, thus reducing the configuration size and manufacturing cost of antennas, and creating better industrial benefits with improved applicability.
摘要翻译：小口径高性能宽带辐射器允许第一和第二组偶极子的两个单元臂向内折叠，在第一/第二组偶极子组的两个单元臂之间形成40°-50°的夹角并且第一/第二单元机架以及第一和第二组偶极子的单元臂在间隔时间线性布置，同时提供弯曲加载部分并且还通过电介质连接。因此，宽带辐射器允许显着降低宽带辐射器的孔径，并且对于散热器阵列的间隙存在较大的调节空间，因此低频带和高频带的干扰较小。这允许改进的性能，从而减少天线的配置尺寸和制造成本，并且通过改进的适用性创造更好的工业效益。

46. 发明申请

US20150141600A1 METHOD FOR SYNTHESIZING HOMOPOLYMER N-VINYL BUTYROLACTAM WITH SUPER-LOW MOLECULAR WEIGHT AND SUPER-LOW RESIDUAL MONOMER 有权
标题翻译：用于合成具有超低分子量和超低残留单体的均聚物N-乙烯基丁二酰胺的方法
公开(公告)号：US20150141600A1
公开(公告)日：2015-05-21
申请号：US14401743
申请日：2012-07-23
申请人： Yu Wang , Wei Liu , Zhan Chen
发明人： Yu Wang , Wei Liu , Zhan Chen
IPC分类号： C08F24/00
CPC分类号： C08F24/00 , C08F4/38 , C08F6/003 , C08F126/06 , C08L39/04
摘要： The present invention relates to a synthesis method of ultra low molecular weight homopolymerized N-vinyl butyrolactam with ultra low residual monomer content, which comprises: using N-vinyl butyrolactam monomers and water with the mass ratio of 3:17˜8:12, then based on the N-vinyl butyrolactam monomers, using 0.5%˜5.0% by weight of initiators, 0.1%˜5.0% by weight of a catalyst, and 0.1%˜10% by weight of a molecular weight regulator; in the presence of an inert gas, adding the above mentioned raw materials in batches, adjusting the pH of the reaction system to 7.0-8.0 with an activator, reacting at the polymerization temperature of 60-85° C.; finally adding a peroxide and keeping the temperature for 2 hours, to obtain an aqueous solution of ultra low molecular weight homopolymerized N-vinyl butyrolactam, drying the aqueous solution to obtain a powdery ultra low molecular weight homopolymerized N-vinyl butyrolactam with ultra low residual monomer content, whose K value is 12-17, whose molecular weight is 2000-15000, and whose residual monomer content is less than 10 ppm, so the present invention is designed skillfully and simple in preparation, the residual monomer content of the ultra low molecular weight homopolymerized N-vinyl butyrolactam with ultra low residual monomer content prepared is less than 10 ppm, and the K value is 12-17, therefore the present invention is suitable for large-scale popularization.
摘要翻译：本发明涉及具有超低残留单体含量的超低分子量均聚N-乙烯基丁内酰胺的合成方法，其包括：使用N-乙烯基丁内酰胺单体和质量比为3：17〜8：12的水，然后基于N-乙烯基丁内酰胺单体，使用0.5重量％〜5.0重量％的引发剂，0.1重量％〜5.0重量％的催化剂和0.1重量％〜10重量％的分子量调节剂; 在惰性气体的存在下，分批加入上述原料，用活化剂将反应体系的pH调节至7.0-8.0，在聚合温度为60-85℃下反应; 最后加入过氧化物并保持温度2小时，得到超低分子量均聚N-乙烯基丁内酰胺水溶液，干燥该水溶液，得到具有超低残留单体的粉状超低分子量均聚N-乙烯基丁内酰胺其K值为12-17，分子量为2000-15000，残留单体含量小于10ppm，本发明设计巧妙简单，超低分子量的残留单体含量制备的超低残留单体含量的均聚的N-乙烯基丁内酰胺重量小于10ppm，K值为12-17，因此本发明适用于大规模普及。

47. 发明授权

US08961537B2 Surgical robot with hybrid passive/active control 有权
标题翻译：具有混合被动/主动控制的手术机器人
公开(公告)号：US08961537B2
公开(公告)日：2015-02-24
申请号：US13216525
申请日：2011-08-24
申请人： Kwok-sui Leung , Shao-Long Kuang , Yu Wang , Chun-sing Chui , Wing-Hoi Cheung , Pak-Leung Tsang , Wai-kin Ng
发明人： Kwok-sui Leung , Shao-Long Kuang , Yu Wang , Chun-sing Chui , Wing-Hoi Cheung , Pak-Leung Tsang , Wai-kin Ng
IPC分类号： A61B19/00 , B25J9/16 , B25J17/00 , B25J18/00 , B25J9/06 , B25J19/00
CPC分类号： B25J9/1689 , A61B34/30 , A61B2034/305 , B25J9/06 , B25J18/005 , B25J19/0004 , G05B2219/39212 , G05B2219/39439 , G05B2219/40415 , Y10S901/23 , Y10S901/28 , Y10T74/20317
摘要： A surgical robot with seven degrees of freedom, including various types of joints, offers a hybrid active-passive control for operation both manually and by programmed navigation. One of the degrees of freedom allows the robot to be moved efficiently around the axis of a patient's body to provide ample workspace for surgical procedures in an operating room.
摘要翻译：具有七个自由度的手术机器人，包括各种类型的关节，提供了手动和通过编程导航操作的混合主动 - 被动控制。自由度之一允许机器人围绕患者身体的轴线有效地移动，以为手术室中的外科手术提供足够的工作空间。

48. 发明授权

US08907539B2 Retaining ring configuration system 有权
标题翻译：保持环配置系统
公开(公告)号：US08907539B2
公开(公告)日：2014-12-09
申请号：US13218841
申请日：2011-08-26
申请人： Yu Wang , Jordan Christopher Baker , John Matthew Sassatelli , John Thomas Sterle
发明人： Yu Wang , Jordan Christopher Baker , John Matthew Sassatelli , John Thomas Sterle
IPC分类号： H02K5/00 , H02K15/00 , H02K3/51
CPC分类号： H02K15/00 , H02K3/51
摘要： A retaining ring configuration system is disclosed. In one embodiment, the system includes a set of adjustment apparatuses configured to contact a portion of a generator rotor, each of the set of adjustment apparatuses including: a base member for contacting the portion of the generator rotor; an adjustment member for adjusting a position of the generator retaining ring relative to the generator rotor; and an actuation member coupled to the base member and operably attached to the adjustment member, the actuation member for actuating movement of the adjustment member to adjust the position of the generator retaining ring relative to the generator rotor.
摘要翻译：公开了一种保持环配置系统。在一个实施例中，系统包括一组调整装置，其被配置为接触发电机转子的一部分，该组调整装置中的每一个包括：用于接触发电机转子部分的基座部件; 用于调节发电机保持环相对于发电机转子的位置的调节构件; 以及致动构件，其联接到所述基座构件并且可操作地附接到所述调节构件，所述致动构件用于致动所述调节构件的运动，以调节所述发电机保持环相对于所述发电机转子的位置。

49. 发明申请

US20140241599A1 PROVIDING REAL-TIME MARKER DETECTION FOR A STENT IN MEDICAL IMAGING 有权
标题翻译：为医学成像提供实时标记检测
公开(公告)号：US20140241599A1
公开(公告)日：2014-08-28
申请号：US13778454
申请日：2013-02-27
申请人： Terrence Chen , Yu Wang , Peter Durlak , Dorin Comaniciu
发明人： Terrence Chen , Yu Wang , Peter Durlak , Dorin Comaniciu
IPC分类号： A61B5/00
CPC分类号： A61B5/0033 , A61B6/12 , A61B6/487 , A61B6/5217 , A61B2576/02 , G06K9/6278 , G06K9/6296 , G06K2209/057 , G06T7/0012 , G06T7/246 , G06T7/277 , G06T2207/30052 , G06T2207/30204
摘要： Real-time marker detection in medical imaging of a stent may be provided. A plurality of frames of image data may be obtained. A plurality of candidate markers for the stent may be determined in the plurality of frames of image data. One or more markers from the plurality of candidate markers may be detected. The detecting may be based on automatic initialization using a subset of frames of image data from the plurality of frames of image data. The detecting may be performed in real-time with the obtaining.
摘要翻译：可以提供支架的医学成像中的实时标记检测。可以获得多个图像数据帧。可以在图像数据的多个帧中确定用于支架的多个候选标记。可以检测来自多个候选标记的一个或多个标记。检测可以基于使用来自图像数据的多个帧的图像数据的帧的子集的自动初始化。可以通过获取来实时检测。

50. 发明申请

US20140231270A1 METHODS OF NONDESTRUCTIVELY DELAMINATING GRAPHENE FROM A METAL SUBSTRATE 有权
标题翻译：从金属基底层析非线性分析石墨的方法
公开(公告)号：US20140231270A1
公开(公告)日：2014-08-21
申请号：US14344040
申请日：2012-09-04
申请人： Kian Ping Loh , Yu Wang
发明人： Kian Ping Loh , Yu Wang
IPC分类号： C01B31/04
CPC分类号： C01B31/0453 , B82Y30/00 , B82Y40/00 , C01B32/186 , C01B32/19 , C01B32/194 , C25F5/00 , Y02E60/366
摘要： Methods of delaminating a graphene film (60) from a metal substrate (50) are disclosed that substantially preserve the metal substrate. The methods include forming a support layer (80) on the graphene film and then performing an electrochemical process in an electrochemical apparatus (10). The electrochemical process creates gas bubbles (36) at the metal-film interface (64), thereby causing the delamination. The graphene film and support layer form a structure (86) that is collected by a take-up roller (120). The support layer and graphene structure are then separated to obtain the graphene film.
摘要翻译：公开了从金属基板（50）分离石墨烯膜（60）的方法，其基本上保持金属基板。所述方法包括在石墨烯膜上形成支撑层（80），然后在电化学装置（10）中进行电化学处理。电化学过程在金属 - 膜界面（64）处产生气泡（36），从而引起分层。石墨烯膜和支撑层形成由卷取辊（120）收集的结构（86）。然后分离支撑层和石墨烯结构以获得石墨烯膜。

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