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41. 发明专利

JP2012240977A Edible jelly-form composition, jelly-form preparation and method for producing jelly-form preparation 有权
标题翻译：可食用形状组合物，制备和制备果胶形式的制备方法
公开(公告)号：JP2012240977A
公开(公告)日：2012-12-10
申请号：JP2011114044
申请日：2011-05-20
申请人： Nitto Denko Corp , 日東電工株式会社
发明人： ASARI DAISUKE , SHISHIDO TAKUYA , HORI MITSUHIKO
IPC分类号： A61K47/42 , A61K9/00 , A61K9/06
摘要： PROBLEM TO BE SOLVED: To provide an edible jelly-form composition which is easy-to-swallow, intraorally soluble edible jelly although it is preferably free of water, a jelly-form preparation obtained by using the edible jelly-form composition, and a method for producing a jelly-form preparation.SOLUTION: The edible jelly-form composition includes: gelatin with a random coil structure obtained by changing the helix structure of slightly water-soluble gelatin; and a nonvolatile organic solvent, does not include water, and is gelled.
摘要翻译：要解决的问题：为了提供易于吞咽的可食用果胶状组合物，尽管其优选不含水，但可溶于水溶性的可食果冻，通过使用可食用果胶状组合物获得的果冻状制剂，以及果冻状制剂的制造方法。解决方案：可食用的果冻状组合物包括：通过改变微溶于水的明胶的螺旋结构获得的具有无规卷曲结构的明胶; 和非挥发性有机溶剂，不包括水，并且凝胶化。版权所有（C）2013，JPO＆INPIT

42. 发明专利

JP2012136496A Sheet-form preparation and method for producing the same 有权
标题翻译：表格制备及其制造方法
公开(公告)号：JP2012136496A
公开(公告)日：2012-07-19
申请号：JP2011091327
申请日：2011-04-15
申请人： Nitto Denko Corp , 日東電工株式会社
发明人： ASARI DAISUKE , SHISHIDO TAKUYA , HORI MITSUHIKO , OKAZAKI TOSHIHIKO , KONISHI TATSUYA
IPC分类号： A61K39/36 , A61K9/70 , A61K47/10 , A61K47/28 , A61K47/34 , A61K47/38 , A61K47/42 , A61P37/08
CPC分类号： A61K39/36 , A61K9/0056 , A61K9/7007 , A61K47/26 , A61K47/42 , A61K2039/54
摘要： PROBLEM TO BE SOLVED: To provide a sheet-form preparation that can be easily dissolved intraorally, allows the dissolution time thereof to be easily controlled, and can stably contain an allergenic protein from cedar pollen.SOLUTION: The sheet-form preparation contains water, gelatin, the allergenic protein from cedar pollen, and a stabilizing agent of the allergenic protein from cedar pollen.
摘要翻译：待解决的问题：为了提供易于口服溶解的片状制剂，可以容易地控制其溶解时间，并且可以稳定地含有来自雪松花粉的变应原性蛋白质。解决方案：片状制剂含有水，明胶，来自雪松花粉的变应原蛋白，以及来自雪松花粉的过敏性蛋白质的稳定剂。版权所有（C）2012，JPO＆INPIT

43. 发明专利

JP2011225532A Film-form preparation and method for producing the same 有权
标题翻译：膜形式制备及其制备方法
公开(公告)号：JP2011225532A
公开(公告)日：2011-11-10
申请号：JP2011049504
申请日：2011-03-07
申请人： Nitto Denko Corp , 日東電工株式会社
发明人： ASARI DAISUKE , HORI MITSUHIKO , SHISHIDO TAKUYA
IPC分类号： A61K47/32 , A61K9/70 , A61K47/38
CPC分类号： A61K9/7007 , A61K8/0241 , A61K9/0056
摘要： PROBLEM TO BE SOLVED: To provide a film-form preparation having a rapid dissolution profile in the mouth and sufficient film strength, and also having excellent appearance and feel.SOLUTION: The film-form preparation contains an edible polymer soluble to water and a polar organic solvent and drug particles insoluble to the polar organic solvent.
摘要翻译：要解决的问题：提供一种在口中具有快速溶出曲线并具有足够的膜强度并且还具有优异的外观和手感的膜形式制剂。解决方案：膜形式制备包含可溶于水和极性有机溶剂的食用聚合物和不溶于极性有机溶剂的药物颗粒。版权所有（C）2012，JPO＆INPIT

44. 发明专利

JP2011207847A Film-form preparation and method for producing the same 审中-公开
标题翻译：膜形式制备及其制备方法
公开(公告)号：JP2011207847A
公开(公告)日：2011-10-20
申请号：JP2010079429
申请日：2010-03-30
申请人： Nitto Denko Corp , 日東電工株式会社
发明人： ASARI DAISUKE , HORI MITSUHIKO , SHISHIDO TAKUYA
IPC分类号： A61K9/70 , A61K31/192 , A61K47/32 , A61K47/34 , A61K47/36 , A61K47/38
CPC分类号： A61K9/7007 , A61K9/0056 , A61K31/192 , A61K31/4045 , A61K31/405
摘要： PROBLEM TO BE SOLVED: To provide a film-form preparation having a rapid dissolution profile in the mouth and a sufficient film strength, and also having excellent appearance and feel.SOLUTION: The film-form preparation includes a water-soluble edible polymer, and water-insoluble drug particles, wherein the average particle size of the drug particles is 0.1-60 μm.
摘要翻译：要解决的问题：提供在口中具有快速溶出曲线并具有足够的膜强度并且还具有优异的外观和手感的膜形式制剂。溶液：膜形式制备包括水溶性可食用聚合物和水不溶性药物颗粒，其中药物颗粒的平均粒径为0.1-60μm。

45. 发明专利

JP2011190205A Selegiline-containing adhesive preparation 有权
标题翻译：含SEIGILINE的粘合剂制剂
公开(公告)号：JP2011190205A
公开(公告)日：2011-09-29
申请号：JP2010056674
申请日：2010-03-12
申请人： Fujimoto Corporation:Kk , Nitto Denko Corp , 日東電工株式会社 , 株式会社フジモト・コーポレーション
发明人： AMEYAMA SATOSHI , NISHIURA ERI , NAKAMURA KOJI , KAMIYAMA MASASHI , MARUO HIROKI , HOSAKA KYOKO , HORI MITSUHIKO
IPC分类号： A61K31/137 , A61K9/70 , A61K47/14 , A61K47/32 , A61P1/08 , A61P25/00 , A61P25/08 , A61P25/16 , A61P25/18 , A61P25/24 , A61P25/28 , A61P27/06 , A61P31/18 , A61P43/00
CPC分类号： A61K9/7061 , A61K31/137 , A61K47/12 , A61K47/14
摘要： PROBLEM TO BE SOLVED: To provide a selegiline-containing adhesive preparation which stably administers selegiline for a long term with a low adverse reaction. SOLUTION: The selegiline-containing adhesive preparation is obtained by forming a pressure-sensitive adhesive layer containing (-)-(R)-N,α-dimethyl-N-2-propynylphenethylamine and/or a pharmaceutically acceptable salt thereof, a pressure-sensitive adhesive, and a component being liquid at 25°C and having two or more ester bonds in one molecule, on at least one side of a support medium. COPYRIGHT: (C)2011,JPO&INPIT
摘要翻译：待解决的问题：提供一种长期具有低不良反应稳定地施用司来吉兰的含司马吉明的粘合剂制剂。解决方案：含司马丙胺的粘合剂制剂是通过形成含有（ - ） - （R）-N，α-二甲基-N-2-丙炔基苯乙胺和/或其药学上可接受的盐的压敏粘合剂层而获得的，压敏粘合剂和在25℃下为液体并且在一个分子中具有两个或更多个酯键的组分，在载体介质的至少一侧上。版权所有（C）2011，JPO＆INPIT

46. 发明专利

CA2801385C ORAL FILM-FORM BASE AND PREPARATION 未知
公开(公告)号：CA2801385C
公开(公告)日：2020-03-24
申请号：CA2801385
申请日：2013-01-09
申请人： NITTO DENKO CORP
发明人： ASARI DAISUKE , HORI MITSUHIKO , SHISHIDO TAKUYA
IPC分类号： C08L39/06 , A61K9/70 , C08J5/18 , C08J9/08 , C08L1/28
摘要： The present invention provides an oral film-form base which has a rapid dissolution profile in the mouth and sufficient film strength, and gives an improved taking property by foaming in the mouth. The oral film-form base includes an edible polymer soluble both in water and in an organic solvent having a solubility parameter of 9.7 or higher, a foaming agent, and an auxiliary foaming agent, wherein the foaming agent is foamable in the presence of water, and the foaming agent and the auxiliary foaming agent each are insoluble in the organic solvent, have an average particle size of 0.1 to 60 µm, and are included in particle states.

47. 发明专利

HK1218877A1 粘膜疫苗組合物未知
公开(公告)号：HK1218877A1
公开(公告)日：2017-03-17
申请号：HK16106939
申请日：2016-06-16
申请人： NITTO DENKO CORP
发明人： FUKASAKA MASAHIRO , HORI MITSUHIKO , OKUBO KATSUYUKI , ASARI DAISUKE , OKAZAKI ARIMICHI , KIYOTOH EIJI , MATSUSHITA KYOHEI
IPC分类号： A61K20060101 , A61P20060101

48. 发明专利

CA2979523A1 ALLERGY VACCINE COMPOSITION 未知
公开(公告)号：CA2979523A1
公开(公告)日：2016-11-10
申请号：CA2979523
申请日：2016-04-28
申请人： NITTO DENKO CORP
发明人： MATSUSHITA KYOHEI , FUKASAKA MASAHIRO , SHISHIDO TAKUYA , ASARI DAISUKE , OKUBO KATSUYUKI , HORI MITSUHIKO
IPC分类号： A61K39/02 , A61K39/35 , A61P1/04 , A61P11/02 , A61P11/06 , A61P17/04 , A61P27/14 , A61P37/02 , A61P37/08 , A61P43/00
摘要： Provided is an allergy vaccine composition that is useful as a preventative or therapeutic agent for allergic diseases, is safe, and can effectively induce immunological tolerance. This allergy vaccine composition is administered to humans or animals that have an allergic disease in order to prevent or treat the allergic disease. The allergy vaccine composition is characterized by containing at least one type of allergen and, as an immunomodulator, at least one type of lipopolysaccharide derived from a Gram-negative bacterium selected from the group consisting of Serratia, Leclercia, Rahnella, Acidicaldus, Acidiphilium, Acidisphaera, Acidocella, Acidomonas, Asaia, Belnapia, Craurococcus, Gluconacetobacter, Gluconobacter, Kozakia, Leahibacter, Muricoccus, Neoasaia, Oleomonas, Paracraurococcus, Rhodopila, Roseococcus, Rubritepida, Saccharibacter, Stella, Swaminathania, Teichococcus, Zavarzinia, Pseudomonas, Achromobacter, Bacillus, Methanoculleus, Methanosarcina, Clostridium, Micrococcus, Flavobacterium, Pantoea, Acetobacter, Zymomonas, Xanthomonas, and Enterobacter, or a salt of said lipopolysaccharide.

49. 发明专利

CA2960940A1 VACCINE PHARMACEUTICAL COMPOSITION FOR TRANSDERMAL ADMINISTRATION 未知
公开(公告)号：CA2960940A1
公开(公告)日：2016-04-07
申请号：CA2960940
申请日：2015-10-01
申请人： NITTO DENKO CORP
发明人： SHISHIDO TAKUYA , ASARI DAISUKE , MATSUSHITA KYOHEI , OKUBO KATSUYUKI , HORI MITSUHIKO
IPC分类号： A61K39/00 , A61K9/70 , A61K39/02 , A61K39/12 , A61K39/39 , A61P31/00 , A61P35/00 , A61P37/04
摘要： The purpose of the present invention is to provide a vaccine pharmaceutical composition for transdermal administration that is safe and useful as an agent for the prevention or treatment of cancer or infection, it being possible to safely and effectively induce a systemic immune response using this vaccine pharmaceutical composition. The present invention is a vaccine pharmaceutical composition for transdermal administration to be administered to the skin of a human or animal, wherein the vaccine pharmaceutical composition for transdermal administration includes: a lipopolysaccharide or salt thereof derived from at least one type of gram-negative bacterium selected from the group consisting of Serratia, Leclercia, Rahnella, Acidicaldus, Acidiphilium, Acidisphaera, Acidocella, Acidomonas, Asaia, Belnapia, Craurococcus, Gluconacetobacter, Gluconobacter, Kozakia, Leahibacter, Muricoccus, Neoasaia, Oleomonas, Paracraurococcus, Rhodopila, Roseococcus, Rubritepida, Saccharibacter, Stella, Swaminathania, Teichococcus, Zavarinia, Pseudomonas, Achromobacter, Baccillus, Methanoculleus, Methanosarcina, Clostridium, Micrococcus, Flavobacterium, Pantoea, Acetobacter, Zymomonas, Xanthomonas, and Enterobacter, as an immunopotentiator; and at least one type of antigen, the mass ratio of the immunopotentiator and the antigen (total mass of immunopotentiator/total mass of antigen) being 0.002-500.

50. 发明专利

AU2014330337A1 Mucosal vaccine composition 未知
公开(公告)号：AU2014330337A1
公开(公告)日：2016-03-17
申请号：AU2014330337
申请日：2014-10-02
申请人： NITTO DENKO CORP
发明人： FUKASAKA MASAHIRO , HORI MITSUHIKO , OKUBO KATSUYUKI , ASARI DAISUKE , OKAZAKI ARIMICHI , KIYOTOH EIJI , MATSUSHITA KYOHEI
IPC分类号： A61K39/39 , A61K9/06 , A61K9/08 , A61K9/12 , A61K9/20 , A61K39/145 , A61P31/04 , A61P31/12 , A61P31/16 , A61P37/04
摘要： The purpose of the present invention is to provide a mucosal vaccine composition that is effective and safe as a prophylactic or therapeutic drug for infections and cancer, which effectively induces a systemic immune response and mucosal immune response, and which can be administered to the oral mucosa, ocular mucosa, ear mucosa, genital mucosa, pharyngeal mucosa, respiratory mucosa, bronchial mucosa, pulmonary mucosa, gastric mucosa, intestinal mucosa, or rectal mucosa. The present invention is a mucosal vaccine composition administered to at least one mucous membrane of a person or animal, said mucous membrane being selected from the group consisting of oral mucosa, ocular mucosa, ear mucosa, genital mucosa, pharyngeal mucosa, respiratory mucosa, bronchial mucosa, pulmonary mucosa, gastric mucosa, intestinal mucosa, and rectal mucosa. The mucosal vaccine composition is characterized by including at least one type of antigen, and, as an immunostimulant, a lipopolysaccharide or a salt thereof derived from at least one gram-negative bacterium selected from the group consisting of Serratia, Leclercia, Rahnella, Acidicaldus, Acidiphilium, Acidisphaera, Acidocella, Acidomonas, Asaia, Belnapia, Craurococcus, Gluconacetobacter, Gluconobacter, Kozakia, Leahibacter, Muricoccus, Neoasaia, Oleomonas, Paracraurococcus, Rhodopila, Roseococcus, Rubritepida, Saccharibacter, Stella, Swaminathania, Teichococcus, Zavarzinia, Pseudomonas, Achromobacter, Bacillus, Methanoculleus, Methanosarcina, Clostridium, Micrococcus, Flavobacterium, Pantoea, Acetobacter, Zymomonas, Xanthomonas, and Enterobacter.

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