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    • 42. 发明授权
    • On-line DOI rebinning for LSO PET/SPECT spatial resolution
    • 在线DOI重组LSO PET / SPECT空间分辨率
    • US06852980B2
    • 2005-02-08
    • US09982344
    • 2001-10-18
    • William F. JonesBernard BendriemMichael E. Casey
    • William F. JonesBernard BendriemMichael E. Casey
    • G01T1/164G01T1/20G01T1/29
    • G01T1/2985A61B6/037A61B6/5205
    • A method and apparatus for on-line DOI rebinning for LSO PET/SPECT to improve spatial resolution, for use in a hybrid Positron Emission Tomography (PET)/Single Photon Emission Computed Tomography (SPECT) system running in PET-mode. Data acquisition hardware is used to feed a detector pair coincidence event stream to an on-line rebinner. Gamma centroid location measurements are made by rastering assumed transaxial and radial head positions and the corresponding rebinning maps for optimal back-projected image resolution. Optimal positions are found by collecting a 64-bit list mode file, assuming a crystal position as the centroid for each of the heads, defining a sequence for varying the assumed positions, making the rebinning look-up tables, rebinning the list mode data, histogramming and reconstructing the image, assessing the image resolution, recording the best resolution number and the associated trial position variables, repeating these on the next trial variable set.
    • 用于LSO PET / SPECT的在线DOI重组以提高空间分辨率的方法和装置,用于以PET模式运行的混合正电子发射断层扫描(PET)/单光子发射计算机断层扫描(SPECT)系统。 数据采集​​硬件用于将检测器对重合事件流馈送到在线重组器。 伽马重心位置测量是通过对假设的横轴和径向头部位置以及相应的重新组合图进行掠夺来实现最佳背投影图像分辨率。 通过收集64位列表模式文件,假设晶体位置为每个头的质心,定义用于改变假定位置的序列,使重新排列查找表,重新列出列表模式数据,找到最佳位置, 直方图和重建图像,评估图像分辨率,记录最佳分辨率数字和相关联的试验位置变量,在下一个试验变量集中重复这些变量。
    • 44. 发明授权
    • Drycleaning residue aftercooker
    • 干洗后残渣
    • US4898601A
    • 1990-02-06
    • US361742
    • 1989-06-01
    • Michael E. Casey
    • Michael E. Casey
    • D06F43/08
    • D06F43/081
    • An aftercooker device for reducing the solvent content of drycleaning solid residues is disclosed as is its application in dry cleaning processes. The aftercooker is adapted for use with fouled disposable filters as well as with the solids which result from the flashing of soil-containing filter backwash. The aftercooker and its use are characterized by the use of ambient to moderately elevated temperatures and low velocity flows of air to remove solvent from residues and to the use of a vent scrubber to recover the solvent so removed.
    • 公开了一种用于减少干洗固体残余物的溶剂含量的余热器装置,其在干洗过程中的应用。 废咖啡机适用于污垢一次性过滤器以及由含有污垢的过滤器反洗液闪烁产生的固体。 余食者及其用途的特征在于使用环境至适度升高的温度和低速空气流以从残余物中除去溶剂,并使用排气洗涤器回收如此去除的溶剂。
    • 45. 发明授权
    • Adaptive framing for dynamic cardiac PET studies
    • 动态心脏PET研究的自适应框架
    • US08538112B2
    • 2013-09-17
    • US13023602
    • 2011-02-09
    • Judson P. JonesMichael E. Casey
    • Judson P. JonesMichael E. Casey
    • G06K9/46G06K9/00A61B5/05
    • G06T11/005A61B6/037A61B6/486A61B6/503A61B6/504A61B6/5205G06F19/00G06T2211/412
    • Methods and computer-readable mediums are provided. In one embodiment, the method acquires patient data. The peak value in the patient data is determined. The patient data is divided into two data segments (i.e., one data segment representing the data before the peak value occurs and a second data segment representing the patient data after the peak occurs). The slopes of the first and second data segments are calculated. Thereafter the slopes are used to determine an appropriate adaptive framing protocol. A number of frames and duration of each frame in the adaptive framing protocol can be calculated or the adaptive framing protocol can be selected from a plurality of framing protocols. Embodiments of the invention also include computer-readable mediums that contain features similar to the features in the above described method.
    • 提供了方法和计算机可读介质。 在一个实施例中,该方法获取患者数据。 确定患者数据中的峰值。 将患者数据划分为两个数据段(即,表示在出现峰值之前的数据的一个数据段,表示出现峰值之后的患者数据的第二数据段)。 计算第一和第二数据段的斜率。 此后,斜率被用于确定适当的自适应框架协议。 可以计算自适应成帧协议中的每一帧的帧数和持续时间,或者可以从多个成帧协议中选择自适应成帧协议。 本发明的实施例还包括包含与上述方法中的特征相似的特征的计算机可读介质。
    • 46. 发明授权
    • Data processing system for multi-modality imaging
    • 多模态成像数据处理系统
    • US08369928B2
    • 2013-02-05
    • US12564635
    • 2009-09-22
    • Roger E. ArseneauJames Frank CarubaMichael E. CaseyMark MusrockNan Zhang
    • Roger E. ArseneauJames Frank CarubaMichael E. CaseyMark MusrockNan Zhang
    • A61B5/05
    • G01T1/1603A61B6/037A61B6/5247
    • A data processing process and embodiment for optimizing the signal path for multi-modality imaging is described. The embodiment and process optimizes the signal to noise ratio in a positron emission tomography (PET) signal path utilizing scintillation crystals, avalanche photo diodes, and charge sensitive preamplifiers in a dual modality MRI/PET scanner. The dual use of both and analog pole zero circuit and a digital filter enables higher signal levels or a fixed ADC input range and thus a higher possible signal to noise ratio in the presence of significant pileup caused by high positron activity. The higher signal to noise ratio is needed in the PET signal architecture, because of the presence of non-modal time varying electromagnetic fields from the MR, which are a significant source of noise for the wideband PET signal modality.
    • 描述了用于优化用于多模态成像的信号路径的数据处理过程和实施例。 实施例和过程利用双重模式MRI / PET扫描器中的闪烁晶体,雪崩光电二极管和电荷敏感前置放大器在正电子发射断层摄影(PET)信号路径中优化信噪比。 双重使用模拟极零电路和数字滤波器可实现更高的信号电平或固定的ADC输入范围,从而在存在由高正电子活动引起的重大堆积的情况下,可能的信噪比更高。 在PET信号架构中需要更高的信噪比,因为存在来自MR的非模态时变电磁场,这是对于宽带PET信号模态的噪声的重要来源。
    • 47. 发明授权
    • Method for improving clinical data quality in positron emission tomography
    • 正电子发射断层扫描技术提高临床资料质量的方法
    • US08058620B2
    • 2011-11-15
    • US12917701
    • 2010-11-02
    • Bernard BendriemMichael E. CaseyCharles C. Watson
    • Bernard BendriemMichael E. CaseyCharles C. Watson
    • G01T1/164
    • G01T1/2985G01T7/005
    • A method for improving clinical data quality in Positron Emission Tomography (PET). The method provides for the processing of PET data to accurately and efficiently determine a data signal-to-noise (SNR) corresponding to each individual clinical patient scan, as a function of a singles rate in a PET scanner. The method relates an injected dose to the singles rate to determine SNR(Dinj), and provides an accurate estimate of quantity proportional to SNR, similar in function to SNR(Dinj). Knowledge of SNR(Dinj) permits determination of peak SNR, optimal dose, SNR deficit, dose deficit, and differential dose benefit. The patient dose is fractionated, with a small calibration dose given initially. After a short uptake, the patient is pre-scanned to determine T, S, and R. An optimal dose is then determined and the remainder is injected.
    • 一种改善正电子发射断层扫描(PET)临床数据质量的方法。 该方法提供PET数据的处理,以便根据PET扫描仪中的单打率来准确有效地确定与每个单独的临床患者扫描相对应的数据信噪比(SNR)。 该方法将注射剂量与单打率相关联以确定SNR(Dinj),并提供与SNR成比例的量的准确估计,其功能类似于SNR(Dinj)。 SNR(Dinj)的知识允许确定峰值SNR,最佳剂量,SNR赤字,剂量缺陷和差异剂量效益。 对患者剂量进行分级,最初给予较小的校准剂量。 经过短暂摄取后,患者被预先扫描以确定T,S和R.然后确定最佳剂量,并注射剩余部分。