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    • 45. 发明授权
    • Method and apparatus for compensating for noise generated by fluctuation
of a medium around an object to be measured
    • 用于补偿由被测物体周围的介质的波动产生的噪声的方法和装置
    • US5777745A
    • 1998-07-07
    • US770461
    • 1996-12-20
    • Lijiang ZengHirokazu MatsumotoKeiji Kawachi
    • Lijiang ZengHirokazu MatsumotoKeiji Kawachi
    • G01B9/02G01B11/00G01B11/14
    • G01B11/00
    • Compensation is performed to eliminate noise generated by fluctuation of a medium that surrounds an object to be measured. First and second laser beams having different wavelengths are generated by a He--Ne laser and a YAG laser, respectively, and are superposed by a first dichroic mirror such that they propagate along a common path. The first laser beam is caused to reflect off the object to be measured, while the second laser beam is reflected by a second dichroic mirror before reaching the object. The first and second reflected laser beams are separated from each other by a third dichroic mirror. The reflected first laser beam is detected by a first position sensor, while the reflected second laser beam is detected by a second position sensor. This makes it possible to compensate for noise generated by fluctuation of the medium around the object to be measured, so that the object can be measured accurately and reliably.
    • 执行补偿以消除由围绕被测量物体的介质的波动产生的噪声。 具有不同波长的第一和第二激光束分别由He-Ne激光器和YAG激光器产生,并且通过第一分色镜叠加,使得它们沿着公共路径传播。 使第一激光束反射离开待测物体,而第二激光束在到达物体之前被第二分色镜反射。 第一和第二反射激光束通过第三分色镜彼此分离。 反射的第一激光束由第一位置传感器检测,而反射的第二激光束由第二位置传感器检测。 这使得可以对由被测量物体周围的介质的波动产生的噪声进行补偿,从而能够精确可靠地测量物体。
    • 48. 发明授权
    • ZAQ ligand-1 antibodies and uses thereof
    • ZAQ配体-1抗体及其用途
    • US07662380B2
    • 2010-02-16
    • US10542664
    • 2004-01-21
    • Hirokazu MatsumotoYasuko HorikoshiYasushi MasudaTetsuya Ohtaki
    • Hirokazu MatsumotoYasuko HorikoshiYasushi MasudaTetsuya Ohtaki
    • A61K39/395C12N5/12
    • C07K16/18A61K2039/505
    • The antibody of the present invention has an extremely high binding ability to human ZAQL-1, can neutralize the activity of human ZAQL-1, and inhibits the action of human ZAQL-1. Therefore, the antibody is useful as a preventive or therapeutic agent or a diagnostic agent for, e.g., digestive diseases, diseases associated with angiogenesis, diseases relating to pregnancy, eating disorders, sleeping disorders, seasonal depression, reproductive dysfunction, endocrine diseases, senile dementia, Alzheimer's disease, various disorders caused by aging, cerebral circulatory disorders, head trauma, spinal injury, epilepsy, anxiety, depression, manic depression, schizophrenia, alcoholism, Parkinson's disease, hypertension, arteriosclerosis, arrhythmia, premenstral syndrome, glaucoma, cancer, AIDS, diabetes, etc.
    • 本发明的抗体对人ZAQL-1具有极高的结合能力,可以中和人ZAQL-1的活性,并抑制人ZAQL-1的作用。 因此,抗体可用作预防或治疗剂或诊断剂,例如消化系统疾病,与血管发生相关的疾病,与怀孕有关的疾病,进食障碍,睡眠障碍,季节性抑郁症,生殖功能障碍,内分泌疾病,老年性痴呆 阿尔茨海默氏病,衰老引起的各种疾病,脑循环障碍,头部创伤,脊髓损伤,癫痫,焦虑,抑郁,躁狂抑郁,精神分裂症,酒精中毒,帕金森病,高血压,动脉硬化,心律失常,前期综合征,青光眼,癌症,AIDS ,糖尿病等
    • 50. 发明申请
    • Antibody and use thereof
    • 抗体及其用途
    • US20060217536A1
    • 2006-09-28
    • US10542664
    • 2004-01-21
    • Hirokazu MatsumotoYasuko Horikoshi
    • Hirokazu MatsumotoYasuko Horikoshi
    • G01N33/574C07K16/30
    • C07K16/18A61K2039/505
    • The antibody of the present invention has an extremely high binding ability to human ZAQL-1, can neutralize the activity of human ZAQL-1, and inhibits the action of human ZAQL-1. Therefore, the antibody is useful as a preventive or therapeutic agent or a diagnostic agent for, e.g., digestive diseases, diseases associated with angiogenesis, diseases relating to pregnancy, eating disorders, sleeping disorders, seasonal depression, reproductive dysfunction, endocrine diseases, senile dementia, Alzheimer's disease, various disorders caused by aging, cerebral circulatory disorders, head trauma, spinal injury, epilepsy, anxiety, depression, manic depression, schizophrenia, alcoholism, Parkinson's disease, hypertension, arteriosclerosis, arrhythmia, premenstral syndrome, glaucoma, cancer, AIDS, diabetes, etc.
    • 本发明的抗体对人ZAQL-1具有极高的结合能力,可以中和人ZAQL-1的活性,并抑制人ZAQL-1的作用。 因此,抗体可用作预防或治疗剂或诊断剂,例如消化系统疾病,与血管发生相关的疾病,与怀孕有关的疾病,进食障碍,睡眠障碍,季节性抑郁症,生殖功能障碍,内分泌疾病,老年性痴呆 阿尔茨海默氏病,衰老引起的各种疾病,脑循环障碍,头部创伤,脊髓损伤,癫痫,焦虑,抑郁,躁狂抑郁,精神分裂症,酒精中毒,帕金森病,高血压,动脉硬化,心律失常,前期综合征,青光眼,癌症,艾滋病 ,糖尿病等