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    • 43. 发明授权
    • 1-heteroaryl-4-aryl-pyrazole microbicides
    • 1-杂芳基-4-芳基 - 吡唑杀微生物剂
    • US4772608A
    • 1988-09-20
    • US886284
    • 1986-07-15
    • Klaus SasseGerd HansslerHans-Georg SchmittWilfried Paulus
    • Klaus SasseGerd HansslerHans-Georg SchmittWilfried Paulus
    • A01N43/40A01N43/56A01N47/06A01N47/16A01N47/22C07D401/04C07D403/04C07D405/14A61K31/505
    • C07D401/04A01N43/56A01N47/06A01N47/16A01N47/22C07D403/04C07D405/14
    • Novel microbicidally active 1-heteroaryl-4-aryl-pyrazole derivatives of the formulae (I) and/or (1A) ##STR1## in which R represents hydrogen or alkyl,R.sup.1 represents halogen, hydroxyl, optionally substituted alkyl, optionally substituted alkoxy, a radical--S(O).sub.p -alkyl which is optionally substituted in the alkyl part, nitro or optionally substituted amino, or represents a fused-on carbocyclic or heterocyclic radicalp represents the integer 0, 1 or 2,n represents an integer from 0 to 5,X represents .dbd.CH--, or represents a nitrogen atom,Y represents CO or SO.sub.2 andR.sup.2 represents hydrogen, in each case optionally substituted alkyl, cycloalkyl or aryl or a heterocyclic radical, or represents OR.sup.3, or also represents SR.sup.3, if Y is CO,whereinR.sup.3 represents optionally substituted alkyl or aryl, orR.sup.2 represents a radical ##STR2## wherein R.sup.4 represents hydrogen or saturated or unsaturated optionally substituted alkyl andR.sup.5 represents hydrogen, saturated or unsaturated, optionally substituted alkyl, optionally substituted cycloalkyl, optionally substituted aryl or an optionally substituted heterocyclic radical, orR.sup.4 and R.sup.5, together with the nitrogen atom on which they are located, form a heterocyclic ring which optionally contains further hetero atoms and can optionally be mono- or polysubstituted by identical or different substituents.
    • 式(I)和/或(1A)的新型杀微生物活性1-杂芳基-4-芳基 - 吡唑衍生物其中R表示氢或烷基,R1表示卤素,羟基 ,任选取代的烷基,任选取代的烷氧基,在烷基部分任选取代的基团-S(O)对 - 烷基,硝基或任选取代的氨基,或表示稠合的碳环或杂环基p表示整数0, 1或2,n表示0〜5的整数,X表示= CH-,或表示氮原子,Y表示CO或SO2,R2表示氢,在各情况下为任意取代的烷基,环烷基或芳基或杂环基, 或表示OR 3,或者也表示SR 3,如果Y是CO,其中R 3表示任选取代的烷基或芳基,或R 2表示基团,其中R 4表示氢或饱和或不饱和的任选取代的烷基,R 5表示氢,饱和或不饱和的 ,可选地 取代的烷基,任选取代的环烷基,任选取代的芳基或任选取代的杂环基,或R 4和R 5与它们所位于的氮原子一起形成任选含有其它杂原子的杂环,并且可以任选地是单或 被相同或不同取代基多取代。
    • 48. 发明授权
    • Wash-resistant, antimicrobially-active fibres and threads and their
manufacture
    • 耐洗涤,抗微生物活性纤维和线及其制造
    • US4663365A
    • 1987-05-05
    • US762652
    • 1985-08-05
    • Ulrich ReinehrKlaus SasseGerhard JagerWalter Radt
    • Ulrich ReinehrKlaus SasseGerhard JagerWalter Radt
    • C08L33/00A01N43/50A01N43/54C08K5/00C08K5/34C08K5/3442C08K5/3445C08K5/3462C08L33/02C08L33/18C08L33/20D01F1/10D01F6/54D06M23/00D06M101/00D06M101/16D06M101/30
    • C08K5/3445A01N43/50A01N43/54C08K5/3462D01F1/103
    • Threads and fibres of synthetic polymers containing from 0.1 to 5% by weight, based on the polymer, of one or more than one compound corresponding to the formula (I) ##STR1## wherein R represents hydrogen or alkyl,R.sup.1 represents halogen, hydroxyl, optionally substituted alkyl, optionally substituted alkoxy, optionally substituted phenoxy, a group --S(O).sub.p -alkyl which is optionally substituted in the alkyl portion, nitro, optionally substituted amino or a condensed carbocyclic or heterocyclic group,p stands for the numerical value 0, 1 or 2,R.sup.2 represents halogen, alkyl which is optionally substituted, alkoxy, alkylmercapto, nitro, cyano, carboxylic acid amide or a condensed carbocyclic group,m represents an integer from 0 to 5,n represents an integer from 0 to 4, the substituents being either identical or different when m and/or n has a value greater than 1, and X, Y and Z are identical or different and represent a nitrogen atom, the group .dbd.CH-- or ##STR2## where R.sup.2 has the meaning indicated above, with the proviso that at least one of the substituents, X, Y and Z is a nitrogen atom,manifest antimicrobial activity which persists even after dyeing and washing processes.
    • 含有0.1至5重量%的合成聚合物的线和纤维,基于聚合物,对应于式(I)的一种或多种化合物其中R表示氢或烷基,R 1表示卤素 ,羟基,任选取代的烷基,任选取代的烷氧基,任选取代的苯氧基,在烷基部分任选取代的-S(O)对 - 烷基,硝基,任选取代的氨基或稠合的碳环或杂环基,p代表 数值0,1或2,R2表示卤素,任选取代的烷基,烷氧基,烷基巯基,硝基,氰基,羧酸酰胺或稠合碳环基团,m表示0至5的整数,n表示 0至4时,当m和/或n具有大于1的值时,取代基相同或不同,X,Y和Z相同或不同,表示氮原子,基团= CH-或其中 R2有意义我 附带说明的是,X,Y和Z中的至少一个取代基是氮原子,表现出即使在染色和洗涤过程之后仍然存在的抗微生物活性。
    • 50. 发明授权
    • N-substituted .beta.-aminocrotonic acid esters
    • US4027037A
    • 1977-05-31
    • US557698
    • 1975-03-12
    • Peter SiegleKlaus SassePeter Rossler
    • Peter SiegleKlaus SassePeter Rossler
    • A01N37/44A01N43/46C07C67/00C07C227/08C07C229/30C07C313/00C07C323/17C07C323/25C07C323/30C07D223/04C07D295/145C07C101/28A01N9/20
    • C07D295/145A01N37/44
    • N-substituted .beta.-aminocrotonic acid esters of the formula ##STR1## in which R.sup.1 is hydrogen, or alkyl or alkenyl with up to 4 carbon atoms;R.sup.2 is straight-chain or branched alkyl or alkenyl with up to 9 carbon atoms, optionally interrupted by O or S, and optionally substituted by halogen, phenoxy, dimethylamino, cyclic alkyl or alkenyl with up to 8 carbon atoms which are optionally substituted by halogen, dimethylamino, or alkyl, alkoxy or alkylthio with up to 4 carbon atoms, phenyl which is optionally substituted by halogen, dimethylamino, phenoxy, or alkyl, alkenyl, acyl, alkoxy, alkenoxy or alkynoxy containing up to 4 carbon atoms, or a 5- or 6-membered heterocyclic ring containing at least one O, S or N hetero-atom and optionally substituted by halogen, alkyl or alkoxy containing up to 4 carbon atoms or R.sub.2 is further more cyclic alkyl or alkenyl with up to 8 carbon atoms optionally substituted by halogen, dimethylamino, or alkyl, alkoxy or alkylthio with up to 4 carbon atoms; phenyl optionally substituted by halogen, dimethylamino, phenoxy, or alkyl, alkenyl, acyl, alkoxy, alkenoxy or alkynoxy containing up to 4 carbon atoms; or a 5- or 6-membered heterocyclic ring containing at least one O, S or N heteroatom and optionally substituted by halogen, or alkyl or alkoxy containing up to 4 carbon atoms; orR.sup.1 and R.sup.2 together with the adjoining nitrogen atom form a heterocyclic structure optionally substituted by lower alkyl with 1-4 carbon atoms and optionally containing further heteroatoms in addition to nitrogen, andR.sup.3 is straight-chain or branched alkyl, alkenyl or alkynyl each with up to 10 carbon atoms, or cyclic alkyl or alkenyl with up to 8 carbon atoms, optionally substituted by halogen, alkoxy or alkyl-thio containing up to 4 carbon atoms, phenyl, 3,4-methylenedioxyphenyl, cyclic alkyl or alkenyl with up to 8 carbon atoms; phenyl optionally substituted by dioxymethylene or alkyl, alkenyl, alkynyl, alkoxy, alkenoxy, alkynoxy or acyl containing up to 4 carbon atoms; or a heterocyclic ring containing up to 6 atoms of which at least one is O, N or S, which ring is optionally bonded via alkyl containing up to 4 carbon atoms,Which inhibit the metamorphosis of arthropods.