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41. 发明授权

US4921948A Sialosyl glyceride and process for producing the same 失效
标题翻译：唾液酸甘油酯及其制备方法
公开(公告)号：US4921948A
公开(公告)日：1990-05-01
申请号：US319064
申请日：1989-03-06
申请人： Shoji Yoshimura , Yuzi Matsuzaki , Mamoru Sugimoto , Masayoshi Ito , Tomoya Ogawa
发明人： Shoji Yoshimura , Yuzi Matsuzaki , Mamoru Sugimoto , Masayoshi Ito , Tomoya Ogawa
IPC分类号： C07H15/04 , A61K31/70 , A61K31/7028 , A61P25/00 , C07H15/06
CPC分类号： C07H15/06
摘要： The present application discloses a new sialosyl glyceride having the following formula, which compound is useful as a remedy for nervous diseases, has an excellent compatability with the living bodies, and is easily producible. ##STR1## wherein R.sup.1 represents a hydrogen atom or XCH.sub.2 CO-- (X being a halogen atom), R.sup.2 represents an alkali metal, a hydrogen atom or a lower alkyl group, R.sup.3 represents a hydrogen atom or --CO(CH.sub.2)mCH.sub.3, R.sup.4 represents --CO(CH.sub.2)mCH.sub.3 amd m and n each represents a number of 0 to 30.

42. 发明授权

US4914195A Process for preparing N-acetylneuraminic acid derivatives 失效
标题翻译： N-乙酰神经氨酸衍生物的制备方法
公开(公告)号：US4914195A
公开(公告)日：1990-04-03
申请号：US664686
申请日：1984-11-26
申请人： Haruo Ogura , Kimio Furuhata , Yoshiyasu Shitori , Masayoshi Ito
发明人： Haruo Ogura , Kimio Furuhata , Yoshiyasu Shitori , Masayoshi Ito
IPC分类号： C07H13/06 , C07H13/04 , C07H13/08 , C07H19/06 , C07H19/16
CPC分类号： C07H13/04 , C07H19/06 , C07H19/16
摘要： A new process for preparing halides of N-acetylneuraminic acids useful as an intermediate in preparing new N-acetylneuraminic acid derivatives having an excellent immunological activity is provided, which process comprises simultaneously acetylating and halogenating an esterified N-acetylneuraminic acid with the aid of an acetyl halide, and according to the process, the halides may be obtained in high yield of about 90%.
摘要翻译：提供了用于制备具有优异免疫活性的新的N-乙酰神经氨酸衍生物的中间体的N-乙酰神经氨酸卤化物的新方法，该方法同时借助乙酰基乙酰化和卤化酯化的N-乙酰神经氨酸卤化物，根据该方法，可以以约90％的高产率获得卤化物。

43. 发明授权

US4797477A Process for preparing sialic acid derivatives 失效
标题翻译：唾液酸衍生物的制备方法
公开(公告)号：US4797477A
公开(公告)日：1989-01-10
申请号：US84018
申请日：1987-08-11
申请人： Shoji Yoshimura , Yoichiro Tani , Youzi Matsuzaki , Masayoshi Ito , Yoshiyasu Shitori , Tomoya Ogawa
发明人： Shoji Yoshimura , Yoichiro Tani , Youzi Matsuzaki , Masayoshi Ito , Yoshiyasu Shitori , Tomoya Ogawa
IPC分类号： C07H15/04 , C07H5/06
CPC分类号： C07H15/04
摘要： The present invention relates to a new process for preparing 3-O-(sodium(5-acetamide-3,5-dideoxy-alpha-D-glycero-D-galacto-2-noneuro pyranosyl)onate-1,2-di-O-tetradecyl-Sn-glycerol (3) consisting essentially of hydrolyzing a 3-O-(C.sub.1-5 alkyl(5-acetamide-4,7,8,9-tetra-O-acetyl-3,5-di-deoxy-alpha-D-glycero-D-galacto-2-noneuropyranosyl)onate)-1,2-di-O-tetradecyl-Sn-glycerol (1) in a single step, in an aqueous lower aliphatic alcohol solution of an alkali metal hydroxide.
摘要翻译：本发明涉及一种新的制备3-O-（5-乙酰胺-3,5-二脱氧-α-D-甘油基-D-半乳-2-氧基吡喃糖基）主要由水解3-O-（C 1-5烷基（5-乙酰胺-4,7,8,9-四-O-乙酰基-3,5-二脱氧）的O-十四烷基-S-甘油（3） -al-D-甘油-D-半乳-2-乙酰基吡喃糖基）甲酸酯）-1,2-二-O-十四烷基-Sn-甘油（1）在碱金属的低级脂族醇水溶液氢氧化物。

44. 发明授权

US4774327A N-glycolylneuraminic acid derivative 失效
标题翻译： N-羟乙酰神经氨酸衍生物
公开(公告)号：US4774327A
公开(公告)日：1988-09-27
申请号：US917559
申请日：1986-10-10
申请人： Haruo Ogura , Kimio Furuhata , Masayoshi Ito , Yoshiyasu Shitori
发明人： Haruo Ogura , Kimio Furuhata , Masayoshi Ito , Yoshiyasu Shitori
IPC分类号： C07H13/04 , C07H13/06 , C07H13/08 , C07H15/04 , C07B59/00
CPC分类号： C07H13/04 , C07H15/04
摘要： This invention provides a novel compound having the following formula: ##STR1## This compound is a useful intermediate for the preparation of N-glycolylneuraminic acid: ##STR2##
摘要翻译：本发明提供了具有下式的新化合物：该化合物是制备N-羟乙酰神经氨酸的有用中间体：

45. 发明授权

US4698332A Expectorant 失效
标题翻译：祛痰药
公开(公告)号：US4698332A
公开(公告)日：1987-10-06
申请号：US773036
申请日：1985-09-06
申请人： Sadanori Ogasawara , Takashi Hanafusa , Katsuhide Kariya , Masayoshi Ito , Yoshiyasu Shitori
发明人： Sadanori Ogasawara , Takashi Hanafusa , Katsuhide Kariya , Masayoshi Ito , Yoshiyasu Shitori
IPC分类号： C07H13/08 , A61K31/35 , A61K31/70 , A61K31/7024 , A61P11/10 , C07H11/00 , C07H13/02 , C07H13/04 , C07H13/06
CPC分类号： A61K31/70 , C07H13/04
摘要： An expectorant capable of acting on the rheological properties of sputum and capable of directly promoting the ciliary motion. The expectorant contains N-acetylneuraminic acid or a pharmaceutically active salt thereof.

46. 发明授权

US4675391A Glycoside derivatives 失效
标题翻译：糖苷衍生物
公开(公告)号：US4675391A
公开(公告)日：1987-06-23
申请号：US832374
申请日：1986-02-24
申请人： Shohei Shibayama , Yuzi Matsuzaki , Shoji Yoshimura , Masayoshi Ito , Yoshiyasu Shitori , Tomoya Ogawa
发明人： Shohei Shibayama , Yuzi Matsuzaki , Shoji Yoshimura , Masayoshi Ito , Yoshiyasu Shitori , Tomoya Ogawa
IPC分类号： C07H15/04 , A61K31/70 , A61K31/7028 , A61P37/00 , C07H3/06 , C07H9/06 , C07H15/26 , C07H15/00
CPC分类号： C07H15/26
摘要： This invention provides a novel compound having a formula such as ##STR1## This invention also provides a process for preparing such a compound. The novel compound has excellent immunological activity.
摘要翻译：本发明提供具有下式的新化合物，例如本发明还提供了制备这种化合物的方法。该新化合物具有优异的免疫活性。

47. 发明授权

US4663443A N-substituted neuraminic acid derivatives 失效
标题翻译： N-取代的神经氨酸衍生物
公开(公告)号：US4663443A
公开(公告)日：1987-05-05
申请号：US729360
申请日：1985-05-01
申请人： Shohei Shibayama , Shoji Yoshimura , Masayoshi Ito , Yoshiyasu Shitori , Tomoya Ogawa
发明人： Shohei Shibayama , Shoji Yoshimura , Masayoshi Ito , Yoshiyasu Shitori , Tomoya Ogawa
IPC分类号： A61K31/70 , A61K31/7028 , A61P37/00 , C07H11/00 , C07H15/04 , C07H5/06
CPC分类号： C07H15/04
摘要： This invention provides a novel compound having a formula such as ##STR1## This invention also provides a process for preparing such a compound. The novel compound has an excellent immunological activity.
摘要翻译：本发明提供具有下式的新化合物，例如本发明还提供了制备这种化合物的方法。该新型化合物具有优异的免疫活性。

48. 发明申请

US20070008210A1 Radar device 审中-公开
标题翻译：雷达设备
公开(公告)号：US20070008210A1
公开(公告)日：2007-01-11
申请号：US10567683
申请日：2003-09-11
申请人： Noriko Kibayashi , Masayoshi Ito
发明人： Noriko Kibayashi , Masayoshi Ito
IPC分类号： G01S13/42 , G01S7/28
CPC分类号： G01S13/931 , G01S13/34 , G01S13/42 , G01S13/44 , G01S13/584 , G01S13/723 , G01S13/726 , G01S2013/9346 , G01S2013/9375
摘要： A radar device tracks with a high accuracy positions and velocities of a plurality of external targets that are close to each other and whose observed direction values are likely to be low. The radar device includes: a target tracking filter for calculating relative distances and relative velocities of a plurality of external targets by signal-processing received signals from an antenna, for calculating the directions of the plurality of external targets by combining, among beam patterns radiated by the antenna, adjacent beam patterns that partially overlap, and for obtaining, from the directions and the relative distances and velocities, observed position values and observed velocity values of the plurality of external targets, to calculate, from the observed position values and the observed velocity values, smoothed values of the position and velocity for each of the external targets; and an intra-tracking-processing-cluster target tracking filter for forming a cluster from the plurality of external targets that are close to each other, for creating gates for the external targets in the cluster, different from those in the target tracking filter, and for performing a correlation process on the observed values of the external targets based on the gates.
摘要翻译：雷达装置跟踪具有彼此接近并且其观察到的方向值可能较低的多个外部目标的高精度位置和速度。雷达装置包括：目标跟踪滤波器，用于通过信号处理来自天线的接收信号来计算多个外部目标的相对距离和相对速度，用于通过将由多个外部目标辐射的波束图案天线，部分重叠的相邻光束图案，以及用于从方向和相对距离和速度获得观察到的多个外部目标的位置值和观测速度值，以从观察到的位置值和观测速度值，平滑的每个外部目标的位置和速度的值; 以及跟踪处理簇目标跟踪滤波器，用于形成来自彼此靠近的多个外部目标的簇，用于与所述目标跟踪滤波器中的不同的集群中的外部目标的门不同;以及用于对基于门的外部目标的观测值进行相关处理。

49. 发明授权

US5937959A Conveyance apparatus 失效
标题翻译：输送装置
公开(公告)号：US5937959A
公开(公告)日：1999-08-17
申请号：US714944
申请日：1996-09-17
申请人： Naoto Fujii , Masayoshi Ito , Tsutomu Hara , Kazuharu Seki
发明人： Naoto Fujii , Masayoshi Ito , Tsutomu Hara , Kazuharu Seki
IPC分类号： A61G5/00 , A61G5/04 , A61G7/10 , B62B3/14 , B62B5/00 , B60K1/00
CPC分类号： A61G7/1046 , A61G5/047 , A61G5/1051 , A61G5/128 , A61G7/10 , A61G7/1048 , A61G7/1051 , A61G7/1086 , A61G7/1096 , B62B3/1476 , B62B5/0026 , A61G2200/34 , A61G2200/52 , A61G2203/38 , B62B2301/08
摘要： A conveyance apparatus, and more particularly, an improvement of a transfer aid mechanism which allows a patient to be transferred from a bed to a wheelchair, for example, is disclosed. The transfer aid mechanism according to the invention includes casters disposed at four locations on a frame, and a drive mechanism which is elevatable with respect to the frame. When required, the drive mechanism is lowered to bring its drive wheel into contact with a floor, and when the drive wheel is driven for rotation under this condition, the transfer aid mechanism may be moved back and forth by utilizing the drive wheel alone. Accordingly, a travelling movement of the transfer aid mechanism is facilitated if there is a carpet laid over the floor or there is a step in the floor.
摘要翻译：更具体地，公开了一种输送装置，特别是例如允许患者从床上转移到轮椅的转移辅助机构的改进。根据本发明的转移辅助机构包括设置在框架上的四个位置处的脚轮和相对于框架可升高的驱动机构。当需要时，降低驱动机构使其驱动轮与地板接触，并且当在该状态下驱动轮驱动旋转时，转移辅助机构可以仅通过驱动轮来回移动。因此，如果地毯铺设在地板上或者地板上有台阶，则便于移动辅助机构的移动。

50. 发明授权

US5309362A Engine torque controlling device responsive to the acceleration of the vehicle and slippage of the wheels 失效
标题翻译：发动机扭矩控制装置，其响应于车辆的加速度和车轮的滑动
公开(公告)号：US5309362A
公开(公告)日：1994-05-03
申请号：US1909
申请日：1993-01-08
申请人： Masayoshi Ito , Masayuki Hashiguchi
发明人： Masayoshi Ito , Masayuki Hashiguchi
IPC分类号： B60K28/16 , B60T8/172 , B60T8/175 , B62D15/02 , F02D29/02 , F02D45/00
CPC分类号： B60K28/16 , B60T8/172 , B60T8/175 , B62D15/02 , B60T2201/16 , B60T2210/12 , B60W2710/0605
摘要： A driving torque controlling system by which a vehicle can drive with safety and certainty while maintaining an appropriate posture without dissatisfying the will of a driver very much. The driving torque controlling system comprises a control signal selecting section which selects, in response to a predetermined change-over condition, one of control signals from a turning control unit for setting an aimed driving torque in response to a magnitude of lateral acceleration applied to the vehicle during turning of the vehicle and a slip control unit for setting an aimed driving torque in response to an amount of slip of a driving wheel of the vehicle. A torque controlling unit receives a selected control signal from the control signal selecting means and reduces the driving torque of the vehicle in response to the received control signal independently of operation by a driver of the vehicle.
摘要翻译：一种行驶转矩控制系统，车辆可以安全可靠地驾驶，同时保持适当的姿势，而不会对司机的意图不感兴趣。驱动力矩控制系统包括控制信号选择部分，该控制信号选择部分响应于预定转换条件选择来自转向控制单元的控制信号中的一个，用于响应于施加到所述转向控制单元的横向加速度的大小来设定目标驱动转矩车辆转向时的车辆和用于根据车辆的驱动轮的滑动量设定目标驱动转矩的滑移控制单元。扭矩控制单元从控制信号选择装置接收所选择的控制信号，并且响应于接收到的控制信号而降低车辆的驱动转矩，而与车辆驾驶员的操作无关。

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