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41. 发明授权

US08043622B2 Method of treating inflammatory lung disease with suppressors of CpG oligonucleotides 有权
标题翻译：用CpG寡核苷酸抑制剂治疗炎症性肺病的方法
公开(公告)号：US08043622B2
公开(公告)日：2011-10-25
申请号：US10682130
申请日：2003-10-07
申请人： Dennis M. Klinman , Hiroshi Yamada
发明人： Dennis M. Klinman , Hiroshi Yamada
IPC分类号： A61K39/38 , C07H19/00 , C07H21/00
CPC分类号： C12N15/117 , C12N2310/151
摘要： The present disclosure relates to oligodeoxynucleotides that suppress an immune response. Methods are disclosed for inhibiting or treating inflammatory lung disease by administering a therapeutically effective amount of a suppressive oligodeoxynucleotide.
摘要翻译：本公开涉及抑制免疫应答的寡脱氧核苷酸。公开了通过施用治疗有效量的抑制性寡脱氧核苷酸来抑制或治疗炎症性肺病的方法。

42. 发明申请

US20110228491A1 SLIDING ELECTRONIC APPARATUS 有权
标题翻译：滑动电子设备
公开(公告)号：US20110228491A1
公开(公告)日：2011-09-22
申请号：US13130394
申请日：2009-11-24
申请人： Takahiro Sakai , Toshiki Yamanaka , Hiroshi Yamada
发明人： Takahiro Sakai , Toshiki Yamanaka , Hiroshi Yamada
IPC分类号： H05K5/03 , H01R12/79
CPC分类号： H04M1/0237 , H02G11/00 , H04M1/026 , H04M1/0277
摘要： A sliding electronic apparatus that prevents foreign matter from entering a housing is provided. In the apparatus, upper housing 1 and lower housing 2 are slidably coupled, and it is switched by sliding one of upper housing 1 and lower housing 2 with respect to the other, a closed state in which operation section 2b provided on lower housing 2 is covered by upper housing 1 and an open state in which operation section 2b is exposed. The apparatus includes opening 1c formed in a lower surface of upper housing 1, opening 2c formed in an upper surface of lower housing 2, and FPC 3 for electrically connecting wiring board 9 and wiring board 10. FPC 3 includes cover portion 3a mounted on the lower surface of upper housing 1 so as to cover opening 1c and cover portion 3b mounted on the upper surface of lower housing 2 so as to cover opening 2c. Cover portion 3a is electrically connected to wiring board 9 in upper housing 1, and cover portion 3b is electrically connected to wiring board 10 in lower housing 2.
摘要翻译：提供防止异物进入壳体的滑动电子设备。在装置中，上壳体1和下壳体2可滑动地联接，并且通过将上壳体1和下壳体2中的一个相对于另一个滑动而切换，其中设置在下壳体2上的操作部2b为闭合状态被上壳体1覆盖，并且操作部分2b暴露的打开状态。该装置包括形成在上壳体1的下表面中的开口1c，形成在下壳体2的上表面中的开口2c，以及FPC 3，用于电连接布线板9和布线板10. FPC 3包括安装在上壳体1的下表面以覆盖开口1c和安装在下壳体2的上表面上的盖部分3b以覆盖开口2c。盖部分3a电连接到上壳体1中的布线板9，并且盖部分3b电连接到下壳体2中的布线板10。

43. 发明申请

US20110054874A1 DISTRIBUTED PROCESSING-TYPE SIMULATOR 有权
标题翻译：分布式处理型模拟器
公开(公告)号：US20110054874A1
公开(公告)日：2011-03-03
申请号：US12869934
申请日：2010-08-27
申请人： Takuro IKEDA , Eiji Kitagawa , Hiroshi Yamada
发明人： Takuro IKEDA , Eiji Kitagawa , Hiroshi Yamada
IPC分类号： G06G7/62 , G06F12/00 , G06F12/02
CPC分类号： G06N3/006 , G06F17/5009 , G06F17/5095
摘要： A simulator simulates the behavior of a plurality of agents existing in the virtual space. Each of a plurality of calculators, communicable with one another, includes a space allocation storage that stores space allocation information, a space allocation control part that updates the space allocation information, an allocation change candidate space extracting part that extracts a divided space to be a candidate for the allocation change, a communication amount estimating part that calculates an amount of communication or an amount of change in communication generated between calculators based on the number of agents, a space allocation change judging part that determines whether or not to allocate a divided space to another calculator based on the amount of communication or the amount of change in communication, and a space allocation change executing part that requests the space allocation control part and other calculators to change the space allocation.
摘要翻译：模拟器模拟存在于虚拟空间中的多个代理的行为。可彼此通信的多个计算器中的每一个包括存储空间分配信息的空间分配存储器，更新空间分配信息的空间分配控制部分，提取分割空间的分配改变候选空间提取部分用于分配改变的候选者，通信量估计部分，其基于代理数量来计算在计算器之间生成的通信量或变化量的通信量估计部，确定是否分配分割空间的空间分配变化判断部基于通信量或通信量变化的另一个计算器，以及请求空间分配控制部分和其他计算器改变空间分配的空间分配改变执行部分。

44. 发明授权

US07851441B2 Water-soluble elastin, process for producing same, and food and medicine containing same 有权
标题翻译：水溶性弹性蛋白，其制造方法以及含有它们的食品和药物
公开(公告)号：US07851441B2
公开(公告)日：2010-12-14
申请号：US11666443
申请日：2005-10-27
申请人： Kouji Okamoto , Hiroshi Yamada , Iori Maeda
发明人： Kouji Okamoto , Hiroshi Yamada , Iori Maeda
IPC分类号： A61K38/39 , C07K14/78 , C07K1/14
CPC分类号： C07K14/78 , A61K38/00
摘要： A low-molecular-weight water-soluble elastin having a molecular weight of about 10,000 to 30,000 and a high-molecular-weight water-soluble elastin having a molecular weight of about 30,000 to 300,000 are provided, 79% to 84% of the constituent amino acids of the elastin comprising proline, glycine, alanine, and valine, 2% to 3% comprising aspartic acid and glutamic acid, 0.7% to 1.3% comprising lysine, histidine, and arginine, and 0.2% to 0.4% comprising desmosine and isodesmosine. The low-molecular-weight water-soluble elastin that is obtained may be used in a functional food or a medicine. Such a high-purity water-soluble elastin may be produced by obtaining pure insoluble elastin by subjecting animal body tissue to a collagen removal treatment and then fragmenting the insoluble elastin by means of a solubilizing liquid. It may be produced simply, merely by adjusting the concentration of an alkaline solution and the reaction time without recovering insoluble elastin from the animal body tissue.
摘要翻译：提供分子量约为10,000至30,000的低分子量水溶性弹性蛋白和分子量为约30,000至300,000的高分子量水溶性弹性蛋白，79％至84％的成分包含脯氨酸，甘氨酸，丙氨酸和缬氨酸的弹性蛋白的氨基酸，包含天冬氨酸和谷氨酸的2％至3％，包含赖氨酸，组氨酸和精氨酸的0.7％至1.3％的氨基酸，以及包含去肌氨酸和异丝氨酸的0.2％至0.4％。获得的低分子量水溶性弹性蛋白可以用于功能性食品或药物中。这样的高纯度水溶性弹性蛋白可以通过使动物体组织进行胶原去除处理，然后利用增溶液使不溶性弹性蛋白破碎而获得纯不溶性弹性蛋白来制造。仅通过调节碱性溶液的浓度和反应时间就可以简单地制备，而不从动物体组织中回收不溶性弹性蛋白。

45. 发明授权

US07832594B2 Liquid storage container with bottom filter 有权
标题翻译：带底部过滤器的液体储存容器
公开(公告)号：US07832594B2
公开(公告)日：2010-11-16
申请号：US10584656
申请日：2004-12-24
申请人： Hiroshi Yamada , Naohito Miyoshi
发明人： Hiroshi Yamada , Naohito Miyoshi
IPC分类号： B67D7/76 , B65D47/18
CPC分类号： A61F9/0008 , B65D1/095 , B65D2205/00
摘要： A liquid storage container (eyedrops container) comprises a container body having a liquid storage portion for containing medical liquid therein, and an instilling portion for allowing the medical liquid to flow out in an opened stage. An aerating device having a filter element and a check valve for allowing ambient air to flow in from outside and preventing the liquid from flowing out to the outside is installed at the bottom of the container body. Further, a cap having an opening member and a valve member is mountable on the container body.
摘要翻译：液体储存容器（滴眼剂容器）包括具有用于容纳医用液体的液体储存部分的容器体和用于允许医用液体在打开阶段中流出的灌注部分。具有过滤元件的充气装置和用于允许环境空气从外部流入并防止液体流出到外部的止回阀安装在容器主体的底部。此外，具有开口构件和阀构件的盖可安装在容器主体上。

46. 发明申请

US20100285994A1 GOLD NANOPARTICLE COMPOSITION, DNA CHIP, NEAR INFRARED ABSORBENT, DRUG CARRIER FOR DRUG DELIVERY SYSTEM (DDS), COLORING AGENT, BIOSENSOR, COSMETIC, COMPOSITION FOR IN VIVO DIAGNOSIS AND COMPOSITION FOR THERAPEUTIC USE 审中-公开
标题翻译：金纳米颗粒组合物，DNA芯片，近红外吸收剂，药物递送系统（DDS）药物载体，染色剂，生物传感器，化妆品，用于体内诊断的组合物和用于治疗用途的组合物
公开(公告)号：US20100285994A1
公开(公告)日：2010-11-11
申请号：US12810764
申请日：2008-12-26
申请人： Chisaka Hosomi , Ikuo Tooyama , Toshiro Inubushi , Shigehiro Morikawa , Hiroshi Yamada
发明人： Chisaka Hosomi , Ikuo Tooyama , Toshiro Inubushi , Shigehiro Morikawa , Hiroshi Yamada
IPC分类号： C40B40/06 , C07F1/12
CPC分类号： A61K49/0017 , A61K8/025 , A61K8/19 , A61K8/70 , A61K9/5115 , A61K41/0052 , A61K47/02 , A61K49/0065 , A61K2800/413 , A61K2800/58 , A61K2800/612 , A61Q19/00 , B22F1/0059 , B22F9/24 , B82Y5/00
摘要： A gold nanoparticle composition is provided that includes a spherical gold nanoparticle and an organic ligand molecule. The organic ligand molecule bonds to the gold nanoparticle. Thus, the gold nanoparticle composition has at least one absorption peak wavelength (plasmon absorption wavelength) within the region of 600-1000 nm. Consequently, the gold nanoparticle composition self-heats when irradiated with electromagnetic waves having a wavelength of 600-1000 nm.
摘要翻译：提供了一种金纳米颗粒组合物，其包括球形金纳米颗粒和有机配体分子。有机配体分子与金纳米颗粒结合。因此，金纳米颗粒组合物在600-1000nm范围内具有至少一个吸收峰波长（等离子体激元吸收波长）。因此，当用具有600-1000nm波长的电磁波照射时，金纳米颗粒组合物自加热。

47. 发明授权

US07820228B2 Medical device and manufacturing method of colored medical device 有权
标题翻译：彩色医疗器械的医疗器械及制造方法
公开(公告)号：US07820228B2
公开(公告)日：2010-10-26
申请号：US11545777
申请日：2006-10-11
申请人： Hiroshi Yamada , Yosuke Taniguchi , Kenji Hioki , Chisaka Aoyama
发明人： Hiroshi Yamada , Yosuke Taniguchi , Kenji Hioki , Chisaka Aoyama
IPC分类号： B05D3/06 , B29C71/02 , G21H5/00
CPC分类号： A61M25/09 , A61M25/0045 , A61M2025/09108
摘要： A method for the manufacture of a medical wire includes manufacturing a fluororesin-coated wire and irradiating with infrared radiation. The fluororesin-coated wire is manufactured with a fluororesin-containing liquid, or fluororesin powder body being applied to the outer circumference of a superelastic alloy wire or of a resin-coated superelastic alloy wire. The fluororesin-coated wire is irradiated with a defined wavelength of infrared radiation for a defined period of time.
摘要翻译：医疗用线的制造方法包括制造含氟树脂被覆线并照射红外线。氟树脂涂布线由含氟树脂的液体制成，或者氟树脂粉末体涂覆在超弹性合金丝或树脂涂层的超弹性合金丝的外周。用限定波长的红外辐射照射含氟树脂涂层的电线一段规定的时间。

48. 发明授权

US07633407B2 Vehicle communication device and memory product 有权
标题翻译：车载通讯设备及内存产品
公开(公告)号：US07633407B2
公开(公告)日：2009-12-15
申请号：US11902844
申请日：2007-09-26
申请人： Katsutoshi Yano , Jun Kawai , Hiroshi Yamada
发明人： Katsutoshi Yano , Jun Kawai , Hiroshi Yamada
IPC分类号： G08G1/16
CPC分类号： G08G1/161 , G08G1/096716 , G08G1/096741 , G08G1/096791
摘要： There is provided a vehicle communication device and a computer program that can avoid a dangerous situation generated when a driver performs an operation such as selection of a vehicle to which notification information is to be sent when communication is made between vehicles and improve safety. A plurality of imaging devices are arranged around a vehicle. The vehicle communication device detects the circumstance of its own vehicle, and refers to a predetermined table based on the detected circumstance, to determine the notification information to be sent and the direction to confirm the existence of other vehicles, and transmits the notification information to the other vehicles detected by the imaging device for detecting the vehicle in the detected direction.
摘要翻译：提供了一种车辆通信装置和计算机程序，其能够避免当驾驶员在车辆之间进行通信时进行诸如选择要发送通知信息的车辆等操作并且提高安全性时产生的危险情况。多个成像装置布置在车辆周围。车辆通信装置检测自身车辆的情况，并且基于检测到的情况参考预定的表，确定要发送的通知信息和确认其他车辆的存在的方向，并将通知信息发送到由成像装置检测到的检测方向上的车辆的其他车辆。

49. 发明申请

US20090246065A1 ALLOY, SHAFT MADE THEREFROM, AND MOTOR WITH SHAFT 审中-公开
标题翻译：合金，轴和其他电机
公开(公告)号：US20090246065A1
公开(公告)日：2009-10-01
申请号：US12255890
申请日：2008-10-22
申请人： Hiroshi Yamada
发明人： Hiroshi Yamada
IPC分类号： C22C38/60
CPC分类号： C22C38/60 , C22C38/001 , C22C38/02 , C22C38/20 , C22C38/38
摘要： A nonmagnetic austenitic stainless steel consists of, all by weight %, 1.5 to 3.5% of Cu, 8.5 to 9.5% of Mn, 0.18 to 0.22% of C, 0.5 to 1.0% of Si, 16.5 to 17.5% of Cr, 0.15 to 0.2% of N, 0.13 to 0.3% of S, and the balance of Fe and inevitable impurities.
摘要翻译：非磁性奥氏体不锈钢全部由Cu，1.5〜3.5％，Mn：8.5〜9.5％，C：0.18〜0.22％，Si：0.5〜1.0％，Cr：16.5〜17.5％，Cr：0.15〜 N的0.2％，S的0.13〜0.3％，Fe和不可避免的杂质的余量。

50. 发明申请

US20090241495A1 PARTICULATE FILTER 有权
标题翻译：颗粒过滤器
公开(公告)号：US20090241495A1
公开(公告)日：2009-10-01
申请号：US12396117
申请日：2009-03-02
申请人： Hiroshi Yamada , Koichiro Harada , Kenji Suzuki , Kenji Okamoto , Akihide Takami
发明人： Hiroshi Yamada , Koichiro Harada , Kenji Suzuki , Kenji Okamoto , Akihide Takami
IPC分类号： B01D39/14 , B01D39/20
CPC分类号： B01D46/247 , B01D46/2451 , B01D46/2455 , B01D46/2459 , B01D2046/2481 , B01D2046/2485 , B01D2046/2496 , B01D2279/30 , F01N3/0222 , Y02T10/20 , Y10S55/30 , Y10T428/24149
摘要： Disclosed is a particulate filter 10, which comprises a filter body 8 including a plurality of filter segments F1, F2 joined to each other by a joining material 7, wherein each of the filter segments includes a plurality of inflow cells each having a closed end on a downstream side in an exhaust-gas flow direction, and a plurality of outflow cells each having a closed end on an upstream side in the exhaust-gas flow direction. The filter segments include a first filter segment located in a central region of the particulate filter and designed to form each of the inflow cells to have an opening area approximately equal to that of each of the outflow cells, and a second filer segment located in at least a part of an outer peripheral region of the particulate filter and designed to form each of the inflow cells to have an opening area greater than that of each of the outflow cells. The present invention can keep the central region of the particulate filter from becoming overheated during a particulate-filter regeneration process, while suppressing a pressure loss.
摘要翻译：公开了一种微粒过滤器10，其包括过滤体8，其包括通过接合材料7彼此连接的多个过滤器段F1，F2，其中每个过滤段包括多个流入单元，每个流入单元各自具有封闭端排气流动方向的下游侧，以及在排气流动方向的上游侧具有封闭端的多个流出电池。过滤器段包括位于颗粒过滤器的中心区域中的第一过滤器段，并被设计成形成每个流入单元以具有与每个流出单元的开口面积大致相等的开口面积，以及位于所述颗粒过滤器的外周区域的至少一部分被设计成形成每个所述流入单元以具有大于每个所述流出单元的开口面积。本发明可以在颗粒过滤器再生过程中保持颗粒过滤器的中心区域变得过热，同时抑制压力损失。

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