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41. 发明授权

US08099165B2 Expert system and method 有权
标题翻译：专家系统和方法
公开(公告)号：US08099165B2
公开(公告)日：2012-01-17
申请号：US13027681
申请日：2011-02-15
申请人： Par Lindh , James Kalgren , Jeffrey E. Stahmann , Rene H. Wentkowski
发明人： Par Lindh , James Kalgren , Jeffrey E. Stahmann , Rene H. Wentkowski
IPC分类号： A61N1/362
CPC分类号： A61N1/37247 , A61N1/3627 , A61N1/37235
摘要： A medical device programmer and a method of operation in which a first data value is received and used in the execution of one or more algorithms. One or more suggested pulse generator settings are calculated from the one or more algorithms based on the first data value, and the one or more suggested pulse generator settings are displayed on an interactive display screen of the medical device programmer. In one embodiment, the first data value is a duration interval of a QRS complex. From the duration interval, suggestions are made as to one or more ventricular chambers in which to provide pacing pulses. Additionally, pacing intervals for an AV delay are suggested based on measured P-R intervals, or pacing intervals for an LV offset are suggested based on a measured duration interval of a V-V-interval between a right ventricular event and a left ventricular event.
摘要翻译：一种医疗设备编程器和操作方法，其中在执行一个或多个算法时接收并使用第一数据值。基于第一数据值从一个或多个算法计算一个或多个建议的脉冲发生器设置，并且一个或多个建议的脉冲发生器设置显示在医疗设备编程器的交互式显示屏幕上。在一个实施例中，第一数据值是QRS复数的持续时间间隔。从持续时间间隔，建议一个或多个心室，其中提供起搏脉冲。另外，基于测量的P-R间隔建议AV延迟的起搏间隔，或者基于右心室事件和左心室事件之间的V-V间隔的测量持续时间间隔来建议LV偏移的起搏间隔。

42. 发明申请

US20110306850A1 Sleep quality data collection and evaluation 有权
标题翻译：睡眠质量数据收集和评估
公开(公告)号：US20110306850A1
公开(公告)日：2011-12-15
申请号：US13215592
申请日：2011-08-23
申请人： John D. Hatlestad , Quan Ni , Jeffrey E. Stahmann , Jesse Hartley , Qingsheng Zhu , Bruce H. KenKnight , Douglas R. Daum , Kent Lee
发明人： John D. Hatlestad , Quan Ni , Jeffrey E. Stahmann , Jesse Hartley , Qingsheng Zhu , Bruce H. KenKnight , Douglas R. Daum , Kent Lee
IPC分类号： A61B5/00
CPC分类号： A61B5/4815 , A61B5/0031 , A61B5/0205 , A61B5/0476 , A61B5/0488 , A61B5/0496 , A61B5/0809 , A61B5/11 , A61B5/4528 , A61B5/4818 , A61N1/3621 , G06F19/00
摘要： A sleep quality assessment approach involves collecting data based on detected physiological or non-physiological patient conditions. At least one of detecting patient conditions and collecting data is performed using an implantable device. Sleep quality may be evaluated using the collected data by an implantable or patient-external sleep quality processor. One approach to sleep quality evaluation involves computing one or more summary metrics based on occurrences of movement disorders or breathing disorders during sleep.
摘要翻译：睡眠质量评估方法包括基于检测到的生理或非生理性患者状况收集数据。使用可植入装置执行检测患者状况和收集数据中的至少一个。可以使用可植入或患者外部的睡眠质量处理器收集的数据来评估睡眠质量。睡眠质量评估的一种方法包括基于睡眠期间的运动障碍或呼吸障碍的发生来计算一个或多个总结度量。

43. 发明授权

US08064997B2 Method and apparatus for treating irregular ventricular contractions such as during atrial arrhythmia 有权
标题翻译：用于治疗不规则心室收缩的方法和装置，例如在心房心律失常期间
公开(公告)号：US08064997B2
公开(公告)日：2011-11-22
申请号：US11423516
申请日：2006-06-12
申请人： David B. Krig , Jesse W. Hartley , Wyatt Stahl , Jeffrey E. Stahmann
发明人： David B. Krig , Jesse W. Hartley , Wyatt Stahl , Jeffrey E. Stahmann
IPC分类号： A61N1/362
CPC分类号： A61N1/3956 , A61N1/3622 , A61N1/395
摘要： A cardiac rhythm management system is capable of treating irregular ventricular heart contractions, such as during atrial tachyarrhythmias such as atrial fibrillation. A first indicated pacing interval is computed based at least partially on a most recent V-V interval duration between ventricular beats and a previous value of the first indicated pacing interval. Pacing therapy is provided based on either the first indicated pacing interval or also based on a second indicated pacing interval, such as a sensor-indicated pacing interval. A weighted averager such as an infinite impulse response (IIR) filter adjusts the first indicated pacing interval for sensed beats and differently adjusts the first indicated pacing interval for paced beats. The system regularizes ventricular rhythms by pacing the ventricle, but inhibits pacing when the ventricular rhythms are stable.
摘要翻译：心律管理系统能够治疗不规则的心室心脏收缩，例如在房性快速性心律失常如心房颤动期间。至少部分地基于心室搏动之间的最新V-V间期持续时间和第一个起搏间隔的先前值来计算第一个起搏间隔。基于第一个起搏间隔或基于第二个起搏间隔（例如传感器指示的起搏间隔）来提供起搏疗法。诸如无限脉冲响应（IIR）滤波器的加权平均器调节感测节拍的第一个起搏间隔，并且针对起搏节奏不同地调节第一个起搏间隔。系统通过起搏心室使心室节律正常化，但是当心室节律稳定时，可抑制起搏。

44. 发明申请

US20110201955A1 Apparatus and Method for Detecting Lung Sounds Using an Implanted Device 有权
标题翻译：使用植入装置检测肺声的装置和方法
公开(公告)号：US20110201955A1
公开(公告)日：2011-08-18
申请号：US13094597
申请日：2011-04-26
申请人： John Hatlestad , Quingsheng Zhu , Jeffrey E. Stahmann
发明人： John Hatlestad , Quingsheng Zhu , Jeffrey E. Stahmann
IPC分类号： A61B5/08
CPC分类号： A61B7/003 , A61N1/36514 , A61N1/36535
摘要： Adventitious lung sounds indicative of lung congestion are detected using an implantable sensor. The sensor is adapted to be positioned adjacent to a pulmonary system and to output signals indicative of lung sounds in response to pulmonary system activity. A controller receives the signals and processes the signals to detect the presence of adventitious lung sounds. A respiratory cycle sensor operating in conjunction with the lung-sound sensor enables classification of an adventitious lung sound according to its time occurrence within the respiratory cycle. Posture sensing in conjunction with lung-sound sensing provides valuable additional information as to the severity of the lung congestion.
摘要翻译：使用植入式传感器检测到指示肺充血的不定肺声。传感器适于邻近肺部系统定位，并响应于肺部系统活动而输出指示肺部声音的信号。控制器接收信号并处理信号以检测不定肺声的存在。与肺声传感器一起操作的呼吸循环传感器可以根据呼吸周期内的时间发生分类不定肺声。结合肺部感觉的姿势感知提供了关于肺充血严重程度的有价值的附加信息。

45. 发明申请

US20110178566A1 PACING AND SENSING VECTORS 有权
标题翻译：遮光和感光矢量
公开(公告)号：US20110178566A1
公开(公告)日：2011-07-21
申请号：US13075244
申请日：2011-03-30
申请人： Jeffrey E. Stahmann , Bruce Tockman , Randy Westlund , Rene H. Wentkowski , Russell E. Anderson
发明人： Jeffrey E. Stahmann , Bruce Tockman , Randy Westlund , Rene H. Wentkowski , Russell E. Anderson
IPC分类号： A61N1/365
CPC分类号： A61N1/36514 , A61N1/3622 , A61N1/365 , A61N1/368 , A61N1/3712
摘要： A method for allowing cardiac signals to be sensed and pacing pulse vectors to be delivered between two or more electrodes. In one embodiment, cardiac signals are sensed and pacing pulse vectors are delivered between at least one of a first left ventricular electrode and a second left ventricular electrode. Alternatively, cardiac signals are sensed and pacing pulse vectors are delivered between different combinations of the first and second left ventricular electrodes and a first supraventricular electrode. In addition, cardiac signals are sensed and pacing pulse vectors are delivered between different combinations of the first and second left ventricular electrode, the first supraventricular electrode and a conductive housing. In an additional embodiment, a first right ventricular electrode is used to sense cardiac signals and provide pacing pulses with different combinations of the first and second left ventricular electrodes, the first supraventricular electrode and the housing.
摘要翻译：一种用于允许感测心脏信号的方法和用于在两个或更多个电极之间递送起搏脉冲矢量的方法。在一个实施例中，感测心脏信号，并且起搏脉冲矢量在第一左心室电极和第二左心室电极中的至少一个之间递送。或者，感测心脏信号，并且起搏脉冲矢量在第一和第二左心室电极和第一室上电极的不同组合之间递送。此外，感测心脏信号，并且起搏脉冲矢量在第一和第二左心室电极，第一室上电极和导电壳体的不同组合之间递送。在另外的实施例中，第一右心室电极用于感测心脏信号并且提供具有第一和第二左心室电极，第一室上电极和外壳的不同组合的起搏脉冲。

46. 发明申请

US20110163834A1 APPARATUS AND METHOD FOR REDUCING INDUCTOR SATURATION IN MAGNETIC FIELDS 有权
标题翻译：用于减小磁场中电感饱和度的装置和方法
公开(公告)号：US20110163834A1
公开(公告)日：2011-07-07
申请号：US12977172
申请日：2010-12-23
申请人： Jeffrey E. Stahmann , Scott R. Stubbs , Arthur Foster
发明人： Jeffrey E. Stahmann , Scott R. Stubbs , Arthur Foster
IPC分类号： H01F17/04
CPC分类号： H01F41/00 , H01F1/344 , H01F3/02 , H01F27/245 , H01F2003/106 , Y10T29/4902
摘要： This document discusses, among other things, an inductive component that can include a core having two portions: (1) a first portion composed of a first material having a first magnetic saturation level; and (2) a second portion composed of a second material selected to provide inductance for the inductive component when an external magnetic field is greater than the first magnetic saturation level. In an example, the first portion can be composed of a material having a relatively low magnetic saturation level (e.g., a ferrite), and the second portion can be composed of a material having a relatively high magnetic saturation level (e.g., a high permeability iron alloy).
摘要翻译：本文件尤其涉及可包括具有两部分的芯的电感元件：（1）由具有第一磁饱和电平的第一材料组成的第一部分; 和（2）由外部磁场大于第一磁饱和度的第二材料组成的第二部分，该第二材料被选择为提供电感元件的电感。在一个示例中，第一部分可以由具有相对低的磁饱和度的材料（例如，铁氧体）组成，并且第二部分可以由具有较高磁饱和度的材料（例如，高磁导率铁合金）。

47. 发明申请

US20110160816A1 APPARATUS TO SELECTIVELY INCREASE MEDICAL DEVICE LEAD INNER CONDUCTOR INDUCTANCE 有权
标题翻译：选择性增加医疗器械引导内导体电感的设备
公开(公告)号：US20110160816A1
公开(公告)日：2011-06-30
申请号：US12905336
申请日：2010-10-15
申请人： Scott R. Stubbs , Jeffrey E. Stahmann , Arthur J. Foster , Ronald W. Kunkel
发明人： Scott R. Stubbs , Jeffrey E. Stahmann , Arthur J. Foster , Ronald W. Kunkel
IPC分类号： A61N1/05 , H01F17/00 , B82Y25/00
CPC分类号： A61N1/056 , A61N1/086
摘要： A medical device lead includes an insulative lead body, outer and inner conductive coils, and a flexible core assembly. The outer conductive coil extends through the lead body and is coupled to a first electrode at a distal end of the outer conductive coil. The inner conductive coil extends coaxially with the outer conductive coil, is coupled to a second electrode at a distal end of the inner conductive coil, and includes a central lumen. The flexible core assembly is disposed in the central lumen and is comprised of a material that has a saturation magnetization of at least about 1.5 T and a relative permeability of greater than one. The flexible core assembly includes a positioning interface configured for manipulation of the flexible core assembly such that the flexible core assembly translates through the central lumen during insertion and extraction of the flexible core assembly.
摘要翻译：医疗器械引线包括绝缘引线体，外部和内部导电线圈以及柔性芯组件。外部导电线圈延伸穿过引线体并且在外部导电线圈的远端处耦合到第一电极。与外部导电线圈同轴地延伸的内部导电线圈耦合到内部导电线圈的远端处的第二电极，并且包括中心腔。柔性芯组件设置在中心腔中，并且由具有至少约1.5T的饱和磁化强度和大于1的相对磁导率的材料构成。柔性芯组件包括配置用于操纵柔性芯组件的定位接口，使得柔性芯组件在插入和拔出柔性芯组件期间通过中心腔平移。

48. 发明申请

US20110160808A1 IMPLANTABLE MEDICAL DEVICE INCLUDING ISOLATION TEST CIRCUIT 失效
标题翻译：包括隔离测试电路的可植入医疗设备
公开(公告)号：US20110160808A1
公开(公告)日：2011-06-30
申请号：US12977158
申请日：2010-12-23
申请人： Michael J. Lyden , Joseph M. Bocek , Jeffrey E. Stahmann
发明人： Michael J. Lyden , Joseph M. Bocek , Jeffrey E. Stahmann
IPC分类号： A61N1/36
CPC分类号： A61N1/37 , A61N1/086 , A61N1/3706 , A61N1/3718 , A61N1/37258 , A61N1/3752 , A61N2001/083
摘要： An implantable medical device can include a hermetically-sealed implantable housing, an exposed first conductor located on or near the housing, and at least one insulated second conductor located near the exposed first conductor. In an example, the implantable medical device can include an isolation test circuit to provide a test stimulus to the exposed first conductor and configured to measure a portion of the test stimulus coupled to the second conductor.
摘要翻译：可植入医疗装置可以包括密封的可植入壳体，位于壳体上或附近的暴露的第一导体，以及位于暴露的第一导体附近的至少一个绝缘的第二导体。在一个示例中，可植入医疗设备可以包括隔离测试电路，以向暴露的第一导体提供测试刺激，并且被配置为测量耦合到第二导体的测试刺激的一部分。

49. 发明申请

US20110144712A1 VENTRICULAR PACING TO AUGMENT ATRIAL NATRIURETIC HORMONE PRODUCTION 有权
标题翻译：静脉输送至胃肠道胃肠激素生产
公开(公告)号：US20110144712A1
公开(公告)日：2011-06-16
申请号：US12966249
申请日：2010-12-13
申请人： Jeffrey E. Stahmann , Ramesh Wariar , Stephen Ruble
发明人： Jeffrey E. Stahmann , Ramesh Wariar , Stephen Ruble
IPC分类号： A61N1/365 , A61N1/362
CPC分类号： A61N1/36585 , A61N1/36 , A61N1/362 , A61N1/3627 , A61N1/365
摘要： Intermittent delivery of ventricular pacing pulses synchronized to occur during an atrial diastole time period can be used to provide atrial stretch therapy and augment the production and release of atrial natriuretic hormone.
摘要翻译：间歇性输送心房舒张期同步发生的心室起搏脉冲可用于提供心房伸展疗法，并增加心房钠尿激素的产生和释放。

50. 发明申请

US20110112592A1 NEURAL STIMULATION SYSTEM TO PREVENT SIMULTANEOUS ENERGY DISCHARGES 有权
标题翻译：神经刺激系统，以防止同时进行的能量消耗
公开(公告)号：US20110112592A1
公开(公告)日：2011-05-12
申请号：US13007739
申请日：2011-01-17
申请人： Imad Libbus , Andrew P. Kramer , William J. Linder , Jeffrey E. Stahmann
发明人： Imad Libbus , Andrew P. Kramer , William J. Linder , Jeffrey E. Stahmann
IPC分类号： A61N1/36 , A61N1/362 , A61N1/39
CPC分类号： A61N1/36114 , A61N1/3962
摘要： Various aspects of the present subject matter relate to a system. Various embodiments of the system comprise at least one port to connect to at least one lead with at least one electrode, at least one stimulator circuit and at least one controller. The at least one stimulator circuit is connected to the at least one port and is adapted to deliver neural stimulation to a neural stimulation target using the at least one electrode. The at least one controller is adapted to determine when another energy discharge other than the neural stimulation to the neural stimulation target is occurring and to prevent delivery of the neural stimulation simultaneously with the other energy discharge. Other aspects and embodiments are provided herein.
摘要翻译：本主题的各个方面涉及系统。系统的各种实施例包括至少一个端口，以连接至少一个引线与至少一个电极，至少一个刺激器电路和至少一个控制器。所述至少一个刺激器电路连接到所述至少一个端口，并且适于使用所述至少一个电极将神经刺激递送到神经刺激靶。所述至少一个控制器适于确定何时发生除了对神经刺激靶的神经刺激以外的其他能量放电，并且防止神经刺激与另一能量放电同时传送。本文提供了其它方面和实施例。

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