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41. 发明申请

US20100012172A1 Photovoltaic Modules Manufactured Using Monolithic Module Assembly Techniques 审中-公开
标题翻译：使用整体模块装配技术制造的光伏组件
公开(公告)号：US20100012172A1
公开(公告)日：2010-01-21
申请号：US12432706
申请日：2009-04-29
申请人： David H. Meakin , James M. Gee , Sysavanh Southimath , Brian Murphy , John Telle , Andrew Mark Mitchell
发明人： David H. Meakin , James M. Gee , Sysavanh Southimath , Brian Murphy , John Telle , Andrew Mark Mitchell
IPC分类号： H01L31/048 , H01L31/042
CPC分类号： H01L31/0201 , H01L31/02013 , H01L31/048 , H01L31/049 , H01L31/0516 , H02S40/34 , Y02E10/50
摘要： Photovoltaic modules comprising back-contact solar cells manufactured using monolithic module assembly techniques comprising a flexible circuit comprising a back sheet and a patterned metallization. The module may comprise busses in electrical contact with the patterned metallization to extract the current. The module may alternatively comprise multilevel metallizations. Interlayer dielectric comprising islands or dots relieves stresses due to thermal mismatch. The use of multiple cord plates enables flexible circuit layouts, thus optimizing the module. The modules preferably comprise a thermoplastic encapsulant and/or hybrid adhesive/solder materials. An ultrathin moisture barrier enables roll-to-roll processing.
摘要翻译：包括使用整体模块组装技术制造的背接触式太阳能电池的光伏模块，该技术包括包含背板和图案化金属化的柔性电路。模块可以包括与图案化的金属化物电接触以提取电流的母线。该模块可以替代地包括多层金属化。包含岛或点的层间电介质减轻了由于热失配引起的应力。使用多个电缆板可实现灵活的电路布局，从而优化模块。模块优选地包括热塑性密封剂和/或混合粘合剂/焊料材料。超薄防潮屏障可实现卷对卷加工。

42. 发明授权

US07567963B2 Thread synchronization with lock inflation methods and apparatus for managed run-time environments 失效
标题翻译：用于管理运行时环境的锁定充电方法和设备的线程同步
公开(公告)号：US07567963B2
公开(公告)日：2009-07-28
申请号：US10878210
申请日：2004-06-28
申请人： Tatiana Shpeisman , Ali-Reza Adl-Tabatabai , Brian Murphy
发明人： Tatiana Shpeisman , Ali-Reza Adl-Tabatabai , Brian Murphy
IPC分类号： G06F7/00
CPC分类号： G06F9/528 , G06F9/3004 , G06F9/30087 , G06F9/52 , Y10S707/99938
摘要： Thread synchronization with lock inflation methods and apparatus for managed run-time environments are disclosed. An example method disclosed herein comprises determining a locking operation to perform on a lock corresponding to the object, performing an optimistically balanced synchronization of the lock if the locking operation is not unbalanced, and modifying a lock shape of the lock if the locking operation is unbalanced.
摘要翻译：公开了具有用于管理的运行时环境的锁定充气方法和装置的线程同步。本文公开的示例性方法包括确定对与对象相对应的锁执行的锁定操作，如果锁定操作不是不平衡则执行锁的乐观平衡的同步，以及如果锁定操作不平衡则修改锁的形状。

43. 发明申请

US20090105639A1 CATHETER DRIVER SYSTEM 审中-公开
标题翻译：导管系统
公开(公告)号：US20090105639A1
公开(公告)日：2009-04-23
申请号：US12344149
申请日：2008-12-24
申请人： Barry Weitzner , Brian Murphy
发明人： Barry Weitzner , Brian Murphy
IPC分类号： A61M25/092 , A61B18/18
CPC分类号： A61M25/1002 , A61B17/12045 , A61B17/12136 , A61B34/70 , A61B2017/12127 , A61B2017/22075 , A61B2017/3409 , A61B2034/301 , A61B2090/0811 , A61M25/0113 , A61M25/1011 , A61M25/10184 , A61M2025/0004 , A61M2025/0008 , A61M2025/0175 , A61M2025/1015 , A61M2025/1052 , A61M2025/1059 , A61M2025/1072
摘要： An apparatus for performing medical procedures on an anatomical body includes an extension with an element near its distal end to be extended into the body, and a driver that moves the extension axially into the body, and that causes flexure of the distal end of the extension. The movement and flexure of the extension is driven by the driver from the proximal end of the extension, and an electronic controller directs the operation of the driver.
摘要翻译：用于在解剖体上执行医疗程序的装置包括具有靠近其远端延伸进入体内的元件的延伸部，以及使延伸部沿轴向移动到体内并使延伸部的远端弯曲的驱动器。延伸部的移动和弯曲由驱动器从延伸部的近端驱动，并且电子控制器引导驾驶员的操作。

44. 发明授权

US07504109B2 Influenza hemagglutinin and neuraminidase variants 有权
标题翻译：流感血凝素和神经氨酸酶变体
公开(公告)号：US07504109B2
公开(公告)日：2009-03-17
申请号：US11133346
申请日：2005-05-20
申请人： Chin-Fen Yang , George Kemble , Kanta Subbarao , Brian Murphy
发明人： Chin-Fen Yang , George Kemble , Kanta Subbarao , Brian Murphy
IPC分类号： A61K39/145 , C12N7/01 , C12N7/02
CPC分类号： C12N7/00 , A61K39/12 , A61K2039/5254 , A61K2039/543 , A61K2039/58 , C07K14/005 , C12N2501/70 , C12N2760/16121 , C12N2760/16122 , C12N2760/16134 , C12N2760/16161 , C12N2760/16162 , C12N2760/16171 , C12Q1/701
摘要： Polypeptides, polynucleotides, methods, compositions, and vaccines comprising (avian pandemic) influenza hemagglutinin and neuraminidase variants are provided.
摘要翻译：提供了包含（禽流感）流感血凝素和神经氨酸酶变体的多肽，多核苷酸，方法，组合物和疫苗。

45. 发明授权

US07491966B2 Semiconductor substrate and process for producing it 有权
标题翻译：半导体衬底及其制造方法
公开(公告)号：US07491966B2
公开(公告)日：2009-02-17
申请号：US11157260
申请日：2005-06-21
申请人： Dirk Dantz , Andreas Huber , Reinhold Wahlich , Brian Murphy
发明人： Dirk Dantz , Andreas Huber , Reinhold Wahlich , Brian Murphy
IPC分类号： H01L29/06
CPC分类号： H01L21/187 , H01L21/3065 , H01L21/324 , H01L21/76251
摘要： A process for producing a semiconductor substrate comprising a carrier wafer and a layer of single-crystalline semiconductor material: a) producing a layer containing recesses at the surface of a donor wafer of single-crystalline semiconductor material, b) joining the surface of the donor wafer containing recesses to the carrier wafer, c) heat treating to close the recesses at the interface between the carrier wafer and the donor wafer to form a layer of cavities within the donor wafer, and d) splitting the donor wafer along the layer of cavities, resulting in a layer of semiconductor material on the carrier wafer. Semiconductor substrates prepared thusly may have a single-crystalline semiconductor layer having a thickness of 100 nm or less, a layer thickness uniformity of 5% or less, and an HF defect density of 0.02/cm2 or less.
摘要翻译：一种制造半导体衬底的方法，包括载体晶片和单晶半导体材料层：a）在单晶半导体材料的施主晶片的表面上产生包含凹陷的层，b）将所述供体的表面晶片容纳凹槽到载体晶片，c）热处理以封闭载体晶片和施主晶片之间的界面处的凹槽，以在施主晶片内形成一层空腔，以及d）沿着该空腔层分裂施主晶片，从而在载体晶片上产生一层半导体材料。因此制备的半导体衬底可以具有厚度为100nm以下，层厚均匀度为5％以下，HF缺陷密度为0.02 / cm 2以下的单晶半导体层。

46. 发明申请

US20080096264A1 Attenuated parainfluenza virus (PIV) vaccines 有权
标题翻译：减毒副流感病毒（PIV）疫苗
公开(公告)号：US20080096264A1
公开(公告)日：2008-04-24
申请号：US11785364
申请日：2007-04-17
申请人： Brian Murphy , Peter Collins , Anna Durbin , Mario Skiadopoulos , Tao Tao , Alexander Schmidt , Jane Bailly
发明人： Brian Murphy , Peter Collins , Anna Durbin , Mario Skiadopoulos , Tao Tao , Alexander Schmidt , Jane Bailly
IPC分类号： C12N7/00 , C07H21/04
CPC分类号： C12N7/00 , A61K39/12 , A61K39/155 , A61K2039/5254 , A61K2039/543 , A61K2039/70 , C07K2319/00 , C12N2760/18434 , C12N2760/18451 , C12N2760/18461 , C12N2760/18634 , C12N2760/18651 , C12N2760/18661 , C12N2760/18671 , C12N2760/18734 , C12N2760/18751 , C12N2760/18761 , C12N2810/60
摘要： The invention provides isolated nucleic acids encoding recombinant genomes or antigenomes of Human Parainfluenza Viruses that are useful as vaccines. The recombinant genomes or antigenomes can be incorporated into expression vectors for production of recombinant viruses in vitro. The invention also provides recombinant Human Parainfluenza viruses having one or more mutations that attenuate replication of the virus in a host.
摘要翻译：本发明提供编码人类副流感病毒的重组基因组或抗原单体的分离的核酸，其可用作疫苗。重组基因组或抗原单体可以并入用于体外重组病毒生产的表达载体中。本发明还提供具有一种或多种突变的重组人副流感病毒，所述突变减弱病毒在宿主中的复制。

47. 发明申请

US20070154454A1 Compositions and methods for treating poxvirus infection 审中-公开
标题翻译：用于治疗痘病毒感染的组合物和方法
公开(公告)号：US20070154454A1
公开(公告)日：2007-07-05
申请号：US10551368
申请日：2004-03-11
申请人： Brian Murphy , Lawrence Blatt
发明人： Brian Murphy , Lawrence Blatt
IPC分类号： A61K38/21 , A61K39/275
CPC分类号： A61K39/285 , A61K38/212 , A61K38/217 , A61K39/12 , A61K39/39 , A61K2039/545 , A61K2039/55522 , A61K2300/00
摘要： The present invention provides methods of treating a poxvirus infection, e.g., a vaccinia virus or a variola virus infection; and methods of reducing viral load, or reducing the time to viral clearance, or reducing morbidity or mortality in the clinical outcomes, in patients suffering from a poxviral infection. The present invention further provides methods of reducing the risk that an individual will develop a pathological poxvirus infection, such as a vaccinia virus infection or a variola virus infection, that has clinical sequelae. The methods generally involve administering a therapeutically effective amount of a Type I or Type III interferon receptor agonist and/or a Type II interferon receptor agonist for the treatment of a pox viral infection.
摘要翻译：本发明提供了治疗痘病毒感染的方法，例如痘苗病毒或天花病毒感染; 以及在患有痘病毒感染的患者中减少病毒载量或减少病毒清除时间或减少临床结果的发病率或死亡率的方法。本发明进一步提供减少患有临床后遗症的病毒性痘病毒感染（例如痘苗病毒感染或天花病毒感染）的风险的方法。所述方法通常包括给予治疗有效量的I型或III型干扰素受体激动剂和/或II型干扰素受体激动剂用于治疗痘病毒感染。

48. 发明申请

US20060159703A1 Production of attenuated respiratory syncytial virus vaccines from cloned nucleotide sequences 有权
标题翻译：从克隆的核苷酸序列产生减毒呼吸道合胞病毒疫苗
公开(公告)号：US20060159703A1
公开(公告)日：2006-07-20
申请号：US10934003
申请日：2004-09-02
申请人： Brian Murphy , Peter Collins , Stephen Whitehead , Alexander Bukreyev , Katalin Juhasz , Michael Teng
发明人： Brian Murphy , Peter Collins , Stephen Whitehead , Alexander Bukreyev , Katalin Juhasz , Michael Teng
IPC分类号： A61K39/155 , C12N7/00 , C07K14/115
CPC分类号： C07K14/005 , A61K39/00 , C12N7/00 , C12N2760/18522 , C12N2760/18561
摘要： Attenuated respiratory syncytial virus (RSV) and vaccine compositions thereof are produced by introducing specific mutations associated with attenuating phenotypes into wild-type or RSV which is incompletely attenuated by cold-passage or introduction of mutations which produce virus having a temperature sensitive (ts) or cold adapted (ca) phenotype. Alternatively, recombinant RSV and vaccine compositions thereof incorporate attenuating and other mutations specifying desired structural and or phenotypic characteristics in an infectious RSV. Recombinant RSV incorporate desired mutations specified by insertion, deletion, substitution or rearrangement of a selected nucleotide sequence, gene, or gene segment in an infectious RSV clone. The immune system of an individual is stimulated to induce protection against natural RSV infection, or multivalently against infection by RSV and another pathogen, such as PIV, by administration of attenuated, biologically derived or recombinant RSV.
摘要翻译：减毒的呼吸道合胞病毒（RSV）及其疫苗组合物通过将与将减毒表型相关的特异性突变引入野生型或RSV，通过冷通道或引入产生具有温度敏感性（ts）或冷适应（ca）表型。或者，重组RSV及其疫苗组合物结合了在感染性RSV中指定所需结构和/或表型特征的减毒和其它突变。重组RSV包含通过在感染性RSV克隆中选择的核苷酸序列，基因或基因片段的插入，缺失，取代或重排而指定的所需突变。通过施用减毒的，生物衍生的或重组的RSV，刺激个体的免疫系统以诱导针对天然RSV感染的保护，或多重抗RSV和另一种病原体如PIV的感染。

49. 发明授权

US07052948B2 Film or layer made of semi-conductive material and method for producing said film or layer 有权
标题翻译：由半导体材料制成的薄膜或层及其制造方法
公开(公告)号：US07052948B2
公开(公告)日：2006-05-30
申请号：US10481537
申请日：2002-06-27
申请人： Brian Murphy , Reinhold Wahlich , Rüdiger Schmolke , Wilfried Von Ammon , James Moreland
发明人： Brian Murphy , Reinhold Wahlich , Rüdiger Schmolke , Wilfried Von Ammon , James Moreland
IPC分类号： H01L21/8238
CPC分类号： H01L21/3223 , H01L21/76251
摘要： The invention relates to a film or a layer made of semi-conducting material with low defect density in the thin layer, and a SOI-disk with a thin silicon layer exhibiting low surface roughness, defect density and thickness variations. The invention also relates to a method for producing a film or a layer made of semi-conductive material. Said method comprises the following steps: a) producing structures from a semi-conductive material with periodically repeated recesses which have a given geometrical structure, b) thermally treating the surface structured material until a layer with periodically repeated hollow spaces is formed under a closed layer on the surface of the material, c) separating the closed layer on the surface along the layer of hollow spaces from the remainder of the semi-conductive material.
摘要翻译：本发明涉及在薄层中具有低缺陷密度的半导体材料制成的膜或层，以及具有低表面粗糙度，缺陷密度和厚度变化的薄硅层的SOI-盘。本发明还涉及一种制造薄膜或由半导体材料制成的层的方法。所述方法包括以下步骤：a）从具有给定几何结构的周期性重复凹槽的半导体材料制造结构，b）热处理表面结构材料，直到形成具有周期性重复的中空空间的层，在所述材料的表面上，c）沿着所述中空空间层与所述半导体材料的其余部分分离所述表面上的所述封闭层。

50. 发明申请

US20060106416A1 Expandable ports and methods for minimally invasive surgery 有权
公开(公告)号：US20060106416A1
公开(公告)日：2006-05-18
申请号：US11255784
申请日：2005-10-21
申请人： Douglas Raymond , Shinikequa White , Richard Pellegrino , Anthony Carlone , William Frasier , Connie Marchek , Brian Murphy , Stephen Connolly , Nicholas Pavento , Sara Dziedzic
发明人： Douglas Raymond , Shinikequa White , Richard Pellegrino , Anthony Carlone , William Frasier , Connie Marchek , Brian Murphy , Stephen Connolly , Nicholas Pavento , Sara Dziedzic
IPC分类号： A61M29/00
CPC分类号： A61B17/3439 , A61B17/02
摘要： An expandable port for minimally invasive surgery includes a first section, a second section, and at least one intermediate section. The port is expandable from a closed configuration in which the first section is proximate the second section along at least a portion of a length of the first section to an expanded configuration in which the first section is spaced apart from the second section. The intermediate portion spans a gap between the first section and the second section when the port is in the expanded configuration.

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