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    • 45. 发明授权
    • Two component dispenser system
    • 双组分分配器系统
    • US06527749B1
    • 2003-03-04
    • US09595961
    • 2000-06-19
    • Mark S. RobyErnie AranyiRichard YagamiH. Jonathan Tovey
    • Mark S. RobyErnie AranyiRichard YagamiH. Jonathan Tovey
    • A61M500
    • A61B17/00491A61B2017/00495A61B2017/2837
    • An applicator is provided for dispensing a first and a second protein solution to form a biological adhesive where the solutions can be deflected by a deflection assembly during dispensing for the adhesive to cover a broad or limited area. The applicator includes a housing having a housing head for enclosing therein a first reservoir containing a first component, and a second reservoir containing a second component. The first and second components are preferably fibrinogen and thrombin which intermix with water to form the first and second protein solutions, respectively. The housing further includes an elongated body portion defining a longitudinal axis for enclosing therein a conduit assembly having a first and a second conduit in communication with the first and second reservoir, respectively. The solutions intermix on an application site to form a fibrin sealant. In an alternate embodiment, the applicator includes two valves. A first valve opens and closes the proximal ends of two conduit assemblies for introducing water or other substance to the reservoirs. A second valve opens and closes the distal ends of the two conduit assemblies to permit and prevent the dispensing of the protein solutions.
    • 提供施用器用于分配第一和第二蛋白质溶液以形成生物粘合剂,其中在分配粘合剂以覆盖宽的或有限的区域期间,溶液可被偏转组件偏转。 施加器包括壳体,该壳体具有壳体头部,用于在其中封装包含第一部件的第一储存器和包含第二部件的第二储存器。 第一和第二组分优选分别与水混合以形成第一和第二蛋白质溶液的纤维蛋白原和凝血酶。 壳体还包括限定纵向轴线的细长主体部分,用于在其中封闭具有分别与第一和第二储存器连通的第一和第二导管的导管组件。 溶液在应用场所混合形成纤维蛋白密封胶。 在替代实施例中,施加器包括两个阀。 第一阀打开和关闭两个导管组件的近端,用于将水或其他物质引入储存器。 第二阀打开和关闭两个导管组件的远端以允许和防止蛋白质溶液的分配。