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    • 41. 发明授权
    • Synthesis of tagged polymers by post-polymerization (trans) amidation
reaction
    • 通过后聚合(反式)酰胺化反应合成标记的聚合物
    • US5260386A
    • 1993-11-09
    • US50592
    • 1993-04-22
    • Dodd W. FongJohn E. Hoots
    • Dodd W. FongJohn E. Hoots
    • C08F8/30C08F8/34C08F8/40
    • C08F8/30C08F8/34
    • A polymer having pendant fluorescent groups is prepared by (trans)amidation of a preformed polymer by reaction with an amine-containing organic fluorescent composition of the Formula III ##STR1## wherein one of R.sub.5 and R.sup.6 may be hydrogen, and wherein within at least one of R.sub.5 and R.sub.6, or within R.sub.5 and R.sub.6 taken together, is an organic fluorescent group wherein the organic fluorescent group includes a polynuclear aromatic ring system. A degree of (trans)amidation derivatization of the polymer is accomplished by heating the admixture of polymer and fluorescent agent for a sufficient period of time. A second amine-containing post-polymerization derivatization agent other than the organic fluorescent composition of Formula III is added to the admixture or to at least a portion of the reaction product of the (trans)amidation derivatization, and is heated therewith to accomplish a degree of sequential or simultaneous post-polymerization derivatization with the second amine-containing post-polymerization derivatization agent.
    • 具有侧视荧光基团的聚合物通过与式III式III的含胺有机荧光组合物(其中R 5和R 6中的一个可以是氢)反应制备预成型聚合物的(反式)酰胺化,其中在 R 5和R 6中的至少一个,或者R 5和R 6中的R 5一起是有机荧光基团,其中有机荧光基团包括多核芳族环系。 通过将聚合物和荧光剂的混合物加热足够的时间来实现聚合物的(反式)酰胺化衍生度。 将除了式III的有机荧光组合物之外的第二种含胺的后聚合衍生化试剂加到混合物中,或者加入到(反式)酰胺化衍生反应的反应产物的至少一部分中, 与第二含胺后聚合衍生化剂进行顺序或同时后聚合衍生化。