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41. 发明授权

US06721476B2 Optical demultiplexer based on three-dimensionally periodic photonic crystals 有权
标题翻译：基于三维周期光子晶体的光解复用器
公开(公告)号：US06721476B2
公开(公告)日：2004-04-13
申请号：US10006520
申请日：2001-12-03
申请人： Aravind Padmanabhan , Anvar Zakhidov , Teresa Marta , Guenadiy Lazarov , Dane Larson
发明人： Aravind Padmanabhan , Anvar Zakhidov , Teresa Marta , Guenadiy Lazarov , Dane Larson
IPC分类号： G02B6293
CPC分类号： G02B6/13 , B82Y20/00 , G02B6/1225
摘要： The invention provides photonic crystal optical demultiplexer devices produced from a three-dimensionally-periodic, porous, dielectric, photonic crystalline structure, which has surfaces or interfaces that are inverse replicas of the surfaces of a monodispersed sphere array. Such a photonic crystal optical demultiplexer comprises a three-dimensionally-periodic, porous, dielectric, photonic crystalline structure, which structure has surfaces or interfaces that are inverse replicas of the surfaces of a monodispersed sphere array, wherein necks exists between neighboring spheres in said sphere array and the average sphere diameter does not exceed about 1000 nm. A first optical waveguide is positioned to direct a broad wavelength band of incident light onto the crystalline structure. A second optical waveguide positioned to receive a narrow wavelength band of reflected light from the crystalline structure.
摘要翻译：本发明提供由三维周期性，多孔的电介质的光子晶体结构产生的光子晶体光解复用器，其具有与单分散球阵列的表面相反的副本的表面或界面。这种光子晶体光解复用器包括三维周期性，多孔的电介质的光子晶体结构，该结构具有表面或界面，其是单分散球体阵列的表面的反向复制，其中颈部存在于所述球体中的相邻球体之间阵列，平均球体直径不超过约1000nm。第一光波导被定位成将入射光的宽波长带引导到晶体结构上。定位成接收来自晶体结构的反射光的窄波长带的第二光波导。

42. 发明授权

US08329118B2 Method and apparatus for determining one or more operating parameters for a microfluidic circuit 有权
标题翻译：用于确定微流体电路的一个或多个操作参数的方法和装置
公开(公告)号：US08329118B2
公开(公告)日：2012-12-11
申请号：US10932662
申请日：2004-09-02
申请人： Aravind Padmanabhan , Peter Reutiman , Eugen I. Cabuz
发明人： Aravind Padmanabhan , Peter Reutiman , Eugen I. Cabuz
IPC分类号： G05D7/00
CPC分类号： G05D7/0694 , B01L3/5027 , B01L2200/0621 , B01L2300/021 , B01L2300/0816 , B01L2400/0487 , Y10T137/0318 , Y10T137/0391 , Y10T137/0396 , Y10T137/8593 , Y10T137/85978 , Y10T436/12
摘要： Methods for determining one or more operating parameters for a timing protocol of a microfluidic circuit are provided. In some embodiments, wet out times are measured for certain flow channels, and start times, flow rates and/or other parameters are calculated so that the various fluids in the microfluidic cartridge arrive at certain locations at a desired time and/or in a desired sequence. To help compensate for process variations, one or more fluidic process monitor components/structures may be fabricated along with the functional components/structures of a microfluidic cartridge. Test may be performed on the process monitor components/structures to help identify process variations in the particular microfluidic cartridge at hand. By using the process monitor data, the timing protocol for a particular microfluidic cartridge may be made more accurate.
摘要翻译：提供了用于确定微流体电路的定时协议的一个或多个操作参数的方法。在一些实施例中，对于某些流动通道测量湿时间，并计算开始时间，流速和/或其它参数，使得微流控筒中的各种流体在期望的时间和/或期望的时间内到达某些位置序列。为了帮助补偿过程变化，可以与微流控盒的功能组件/结构一起制造一个或多个流体过程监控组件/结构。可以在过程监视器组件/结构上执行测试，以帮助识别手头上特定微流控筒的过程变化。通过使用过程监控数据，可以使特定微流控盒的定时协议更准确。

43. 发明申请

US20120173204A1 BUILDING MAP GENERATION USING LOCATION AND TRACKING DATA 审中-公开
标题翻译：使用位置和跟踪数据构建地图生成
公开(公告)号：US20120173204A1
公开(公告)日：2012-07-05
申请号：US13092038
申请日：2011-04-21
申请人： Aravind Padmanabhan , Steve Huseth
发明人： Aravind Padmanabhan , Steve Huseth
IPC分类号： G06F17/50
CPC分类号： G01C15/00 , G01C21/206 , G01S13/89 , G01S15/89
摘要： A system and method are presented for producing a model of the interior of a building. The model is capable of receiving and dynamically incorporating input from various sources including, for example, existing static map data, data such as annotations and updates provided by persons on the scene but outside the building, and real-time data from sensors located on mobile persons or assets that are dynamically moving inside the building. In some cases, the moving persons or assets inside the building may carry a unit that emits sound or electromagnetic pulses, which reflect off the immediate surroundings in a particular room or portion of the building, and sense the reflected pulses. The reflections from relatively close features may arrive at the sensor more quickly than those from relatively distant features, so that temporal analysis of the reflected pulse may provide information about features in the building as a function of their distance away from the unit. Pulses may be emitted and received at multiple locations in a room or portion of the building. The reflected pulses may be analyzed, using specific time shifts that correspond to round-trip travel times in particular directions, so that the actual locations of features may be identified. By walking from room-to-room throughout the interior of a building and performing such analysis, much or all of the interior of a building may be mapped.
摘要翻译：提出了一种用于生产建筑物内部模型的系统和方法。该模型能够接收并动态地并入来自各种来源的输入，包括例如现有的静态地图数据，诸如注释和数据，例如场景中的人，但在建筑物之外提供的更新，以及位于移动设备上的传感器的实时数据在建筑物内动态移动的人员或资产。在某些情况下，建筑物内的移动人员或资产可能会携带发出声音或电磁脉冲的单元，这些单元反射出建筑物的特定房间或部分的周围环境，并感测到反射的脉冲。来自相对较近的特征的反射可以比来自相对远的特征的那些更快地到达传感器，使得反射脉冲的时间分析可以作为它们离开该单元的距离的函数来提供关于建筑物中的特征的信息。脉冲可以在建筑物的房间或部分的多个位置发射和接收。可以使用与特定方向上的往返旅行时间对应的特定时间偏移来分析反射脉冲，从而可以识别特征的实际位置。通过从建筑物内部的房间到室内的行走，进行这种分析，可以映射建筑物的大部分或全部内部空间。

44. 发明授权

US07975525B2 Self-calibrating sensor 有权
标题翻译：自校准传感器
公开(公告)号：US07975525B2
公开(公告)日：2011-07-12
申请号：US11803968
申请日：2007-05-16
申请人： Ulrich Bonne , Peter Tobias , Aravind Padmanabhan , Thomas M. Rezachek
发明人： Ulrich Bonne , Peter Tobias , Aravind Padmanabhan , Thomas M. Rezachek
IPC分类号： G01N21/00
CPC分类号： G01N33/0006
摘要： Embodiments of the present invention relate to a gas sensor comprising a flow channel, a concentration modulator positioned in the flow channel, a gas generator in contact with the flow channel, one or more gas detectors positioned downstream of the concentration modulator and gas generator and a pump.
摘要翻译：本发明的实施例涉及一种气体传感器，其包括流动通道，位于流动通道中的浓度调节器，与流动通道接触的气体发生器，位于浓缩调节器和气体发生器下游的一个或多个气体检测器和泵。

45. 发明申请

US20070190525A1 ASSAY IMPLEMENTATION IN A MICROFLUIDIC FORMAT 有权
标题翻译：微流控格式中的测定实现
公开(公告)号：US20070190525A1
公开(公告)日：2007-08-16
申请号：US11618502
申请日：2006-12-29
申请人： Yuandong Gu , Aravind Padmanabhan
发明人： Yuandong Gu , Aravind Padmanabhan
IPC分类号： C12Q1/70 , G01N33/569 , G01N33/554 , C12M3/00
CPC分类号： G01N15/1459 , B01L3/502715 , B01L3/502776 , B01L9/527 , B01L2200/0636 , B01L2200/0647 , B01L2200/0684 , B01L2200/10 , B01L2200/143 , B01L2200/146 , B01L2300/0816 , B01L2300/0867 , B01L2300/087 , B01L2300/0887 , B01L2400/0487 , G01N15/1484 , G01N33/5094 , G01N2015/0073 , G01N2015/008 , G01N2015/0084 , G01N2015/0088 , G01N2015/1486 , G01N2035/00158 , G01N2333/445 , G01N2333/70514 , G01N2333/70589 , G01N2800/26 , Y02A50/58 , Y10T436/2575
摘要： An assay implementation in a microfluidic format in a cartridge relating to a point-of-care instrument platform for monitoring and diagnosing infectious diseases (e.g., AIDS and malaria). The platform may also provide a complete blood count. The instrument platform may hold the cartridge and a portion of an optical system for fluorescent and scattered light related analyses of blood sample in a flow channel of the cartridge.
摘要翻译：在与用于监测和诊断感染性疾病（例如艾滋病和疟疾）的护理点仪器平台相关的盒中的微流体形式的测定实现。该平台还可以提供完整的血液计数。仪器平台可以将墨盒和一部分光学系统用于荧光和散射光相关分析的血液样品在墨盒的流动通道中。

46. 发明授权

US07215425B2 Optical alignment for flow cytometry 有权
标题翻译：流式细胞仪的光学校准
公开(公告)号：US07215425B2
公开(公告)日：2007-05-08
申请号：US10824859
申请日：2004-04-14
申请人： Tom Rezachek , Aravind Padmanabhan , Bernard Fritz
发明人： Tom Rezachek , Aravind Padmanabhan , Bernard Fritz
IPC分类号： G01B11/00
CPC分类号： G01B11/272 , G01N15/1434 , G01N15/1456 , G01N15/1459 , G01N35/085 , G01N2015/0069 , G01N2015/0073 , G01N2015/008 , G01N2015/0238 , G01N2015/1075 , G01N2015/1413
摘要： An optical alignment system for aligning a light beam with a core flow in a flow stream. The flow stream may have a sheath fluid and a core flow, where the core flow has a current position within the flow stream. A light source may be used to produce a light beam, and an optical element may be used to direct the light beam at the core flow. In some illustrative embodiments, an actuator is provided for moving the optical element, light source and/or flow stream such that the light directed by the optical element is aligned with the current position of the core flow.
摘要翻译：一种用于将光束与流动流中的核心流对准的光学对准系统。流动流可以具有护套流体和芯流，其中核心流具有流动流内的当前位置。可以使用光源来产生光束，并且可以使用光学元件来引导光束在核心流动。在一些说明性实施例中，提供致动器用于移动光学元件，光源和/或流动流，使得由光学元件引导的光与核心流的当前位置对准。

47. 发明申请

US20060263888A1 DIFFERENTIAL WHITE BLOOD COUNT ON A DISPOSABLE CARD 审中-公开
标题翻译：不可比拟的白血病计数器
公开(公告)号：US20060263888A1
公开(公告)日：2006-11-23
申请号：US11306508
申请日：2005-12-30
申请人： Bernard Fritz , Aravind Padmanabhan , Peter Reutiman
发明人： Bernard Fritz , Aravind Padmanabhan , Peter Reutiman
IPC分类号： G01N33/50
CPC分类号： B01L3/502715 , B01L3/502776 , B01L9/527 , B01L2200/027 , B01L2200/0636 , B01L2200/10 , B01L2200/143 , B01L2300/0672 , B01L2300/0816 , B01L2300/087 , B01L2400/0481 , B01L2400/0487 , B01L2400/0605 , G01N33/5002 , G01N2015/008 , G01N2015/1486
摘要： An apparatus and approach for performing multipart differentiation such as, for example, three, four and five part differentiation of white blood cells in a card or cartridge. The may be a combination of several kinds of lysing and/or staining/marking in a variety of sequential and parallel runs to achieve the differentiation of the cells. Various cell counts may also be performed.
摘要翻译：用于进行多部分微分的装置和方法，例如卡或盒中白细胞的三，四和五部分分化。可以是多种顺序和平行运行中的几种裂解和/或染色/标记的组合，以实现细胞的分化。也可以执行各种细胞计数。

48. 发明授权

US07109842B1 Robust fluid flow and property microsensor made of optimal material 失效
标题翻译：坚固的流体流动和性能微传感器由最佳材料制成
公开(公告)号：US07109842B1
公开(公告)日：2006-09-19
申请号：US09656694
申请日：2000-09-07
申请人： Aravind Padmanabhan , Ulrich Bonne , Michael James Haji-Sheikh
发明人： Aravind Padmanabhan , Ulrich Bonne , Michael James Haji-Sheikh
IPC分类号： H01C7/02
CPC分类号： G01F1/6842 , G01F1/6845 , G01F5/00 , G01N1/2247 , G01N25/18 , G01N25/488 , G01N33/0014 , G01N2001/2285
摘要： A robust sensor that incorporates the necessary physical structure and thermal characteristics is capable of measuring fluid flow and properties under harsh environmental conditions. The sensor die is made of a material with thermal conductivity tailored to provide the thermal transmission characteristics necessary to avoid saturation of the sensor, thus enabling the measurement of high mass flux airflow and liquid properties under high pressure and often harsh environments not previously available for silicon based sensors. The robust sensor further has internal vias for back-side electrical connection, thus avoiding electrical and mechanical interference with the measurements. All of these features come together to provide a microsensor which is capable of reliable, i.e. stable, wide dynamic range and rapid-response operation under harsh environments.
摘要翻译：结合必要的物理结构和热特性的坚固的传感器能够在恶劣的环境条件下测量流体流动和性能。传感器芯片由具有导热性的材料制成，以提供避免传感器饱和所必需的热传递特性，从而能够在高压和常常恶劣的环境下测量高质量通量气流和液体性能，以前不可用于硅基于传感器。坚固的传感器还具有用于背面电气连接的内部通孔，从而避免了电气和机械干扰测量。所有这些特征汇集在一起，以提供能够在恶劣环境下可靠，即稳定，宽动态范围和快速响应操作的微型传感器。

49. 发明申请

US20060046300A1 Method and apparatus for determining one or more operating parameters for a microfluidic circuit 有权
标题翻译：用于确定微流体电路的一个或多个操作参数的方法和装置
公开(公告)号：US20060046300A1
公开(公告)日：2006-03-02
申请号：US10932662
申请日：2004-09-02
申请人： Aravind Padmanabhan , Peter Reutiman , Eugen Cabuz
发明人： Aravind Padmanabhan , Peter Reutiman , Eugen Cabuz
IPC分类号： G05D7/00
CPC分类号： G05D7/0694 , B01L3/5027 , B01L2200/0621 , B01L2300/021 , B01L2300/0816 , B01L2400/0487 , Y10T137/0318 , Y10T137/0391 , Y10T137/0396 , Y10T137/8593 , Y10T137/85978 , Y10T436/12
摘要： Methods for determining one or more operating parameters for a timing protocol of a microfluidic circuit are provided. In some embodiments, wet out times are measured for certain flow channels, and start times, flow rates and/or other parameters are calculated so that the various fluids in the microfluidic cartridge arrive at certain locations at a desired time and/or in a desired sequence. To help compensate for process variations, one or more fluidic process monitor components/structures may be fabricated along with the functional components/structures of a microfluidic cartridge. Test may be performed on the process monitor components/structures to help identify process variations in the particular microfluidic cartridge at hand. By using the process monitor data, the timing protocol for a particular microfluidic cartridge may be made more accurate.
摘要翻译：提供了用于确定微流体电路的定时协议的一个或多个操作参数的方法。在一些实施例中，对于某些流动通道测量湿时间，并计算开始时间，流速和/或其它参数，使得微流控筒中的各种流体在期望的时间和/或期望的时间内到达某些位置序列。为了帮助补偿过程变化，可以与微流控盒的功能组件/结构一起制造一个或多个流体过程监控组件/结构。可以在过程监视器组件/结构上执行测试，以帮助识别手头上特定微流控筒的过程变化。通过使用过程监控数据，可以使特定微流控盒的定时协议更准确。

50. 发明授权

US06991847B2 Light emitting photonic crystals 有权
公开(公告)号：US06991847B2
公开(公告)日：2006-01-31
申请号：US10068273
申请日：2002-02-07
申请人： Aravind Padmanabhan , Ray H. Baughman , Anvar A. Zakhidov , Guenadiy Lazarov
发明人： Aravind Padmanabhan , Ray H. Baughman , Anvar A. Zakhidov , Guenadiy Lazarov
IPC分类号： B32B3/26 , C23F4/04
CPC分类号： B82Y20/00 , C30B5/00 , C30B29/60 , G02B6/1225 , Y10T428/249953 , Y10T428/249974 , Y10T428/249979 , Y10T428/249981 , Y10T428/24999 , Y10T428/8305
摘要： The invention relates to processes for the synthesis of 2-D and 3-D periodic porous silicon structures and composites with improved properties having the advantages of porous silicon and photonic bandgap materials. Photonic crystals comprise a two dimensionally periodic or three dimensionally periodic microporous structural matrix of interconnecting, crystallographically oriented, monodispersed members having voids between adjacent members, and said members additionally having randomly nanoporous surface porosity. The silicon nanofoam material shows enhanced and spectrally controlled/tunable photoluminescence and electroluminesce and finds use as transparent electrodes, high-lumonosity light emitting diodes (LEDs), wavelength division multiplexors, high-active-area catalyst supports, photonic bandgap lasers, silicon-based UV detectors, displays, gas sensors, and the like.

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