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    • 47. 发明申请
    • Process for the Production of Fatty Acid Alkyl Esters
    • 脂肪酸烷基酯的制备方法
    • US20100234458A1
    • 2010-09-16
    • US12304078
    • 2007-05-16
    • Eric DubreucqAlbrecht WeissBernhard GutscheBernd FabryGuy Moulin
    • Eric DubreucqAlbrecht WeissBernhard GutscheBernd FabryGuy Moulin
    • A61K8/37C12P7/64A61Q90/00A23L1/28A23D9/00
    • C12P7/649A23K10/10C10L1/026C11C3/003Y02E50/13Y02E50/17
    • Disclosed is an improved process for the production of fatty acid lower alkyl esters according to formula (I) R1CO—OR2   (I) in which R1CO represents a linear or branched acyl moiety having from about 6 to about_22 carbon atoms and 0 to 6 double bonds and wherein R2 is a linear or branched alkyl moiety having 1 to 6 carbon atoms, by transesterification of triglycerides or fatty acid esters using C1-C6 aliphatic alcohols, which includes the steps of (a) providing an aqueous mixture of aliphatic C1-C6 alcohol by fermenting in a first reactor a carbon_source comprising carbohydrates and/or glycerol produce a fermentation broth comprising said aliphatic C1-C6 alcohol, (b) providing in a second reactor a triglyceride and/or an ester of a fatty acid, together with a biocatalyst capable of effecting a transesterification reaction, (c) transferring said aqueous aliphatic C1-C6 alcohol mixture obtained from said first reactor into said_second reactor to provide_a two-phase system, and (d) effecting the transesterification reaction to produce said fatty acid lower alkyl ester and a glycerol- or alcohol-containing aqueous phase. The products thus obtained are particularly useful as components of the fuel known as biodiesel.
    • 公开了一种改进的根据式(I)R1CO-OR2(I)的脂肪酸低级烷基酯的制备方法,其中R 1 CO表示具有约6至约22个碳原子和0至6个双键的直链或支链酰基部分 并且其中R 2是具有1至6个碳原子的直链或支链烷基部分,通过使用C 1 -C 6脂族醇进行甘油三酯或脂肪酸酯的酯交换反应,其包括以下步骤:(a)提供脂族C1-C6醇的水性混合物 通过在第一反应器中发酵包含碳水化合物和/或甘油的碳源产生包含所述脂族C 1 -C 6醇的发酵液,(b)在第二反应器中提供甘油三酯和/或脂肪酸酯以及生物催化剂 能够进行酯交换反应,(c)将从所述第一反应器获得的脂族C1-C6醇混合物混合物转移到所述第二反应器中以提供两相体系,和(d) 进行酯交换反应以产生所述脂肪酸低级烷基酯和含甘油或醇的水相。 这样得到的产物特别适用于称为生物柴油的燃料的组分。