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    • 42. 发明授权
    • Line pressure control system for automatic transmission
    • 自动变速器线路压力控制系统
    • US4982621A
    • 1991-01-08
    • US306606
    • 1989-02-06
    • Akihiko Sano
    • Akihiko Sano
    • F16H59/40F16H59/42F16H59/48F16H61/00F16H61/02F16H61/04F16H61/10
    • F16H61/0437F16H2061/0087F16H2061/0096F16H2061/0255Y10T477/69395Y10T477/693964Y10T477/693973
    • The magnitude of line pressure used for activating a friction device to be engaged during a shift is controlled based upon data stored in a RAM of a microcomputer based control unit. The data is updated based on the result of evaluation of a shift which has taken place and the magnitude of line pressure is controlled based on this updated data at a future or subsequent time of occurrence of a shift of the same kind. This learning control to update this data stored in the RAM is effected using an inertia phase time measured as criteria which the judgement of the quality of a shift is based on. The total length of time for a shift is measured and when the total length of time is greater than a predetermined value, the data in the RAM is modulated to cause a prompt substantial increase in the magnitude of line pressure, so that the line pressure will be increased at the subsequent future time of the occurrence of a shift of the same kind.
    • 基于存储在基于微机的控制单元的RAM中的数据来控制用于激活在换档期间接合的摩擦装置的线压力的大小。 基于已经发生的班次的评估结果更新数据,并且在相同类型的班次的发生的未来或随后的时间期间,根据该更新数据来控制线路压力的大小。 用于更新存储在RAM中的数据的该学习控制是使用作为基于质量的判断基于的标准测量的惯性相位时间来实现的。 测量移位的总时间长度,并且当总时间长度大于预定值时,RAM中的数据被调制以引起线路压力的大幅度的显着增加,从而线路压力将 在随后的同一时间发生变化的时候会增加。
    • 47. 发明授权
    • Sustained-release drug formulations for implantation
    • 用于植入的持续释放药物制剂
    • US07247312B1
    • 2007-07-24
    • US10089694
    • 2000-10-31
    • Akihiko SanoMasako KajiharaHiroo Maeda
    • Akihiko SanoMasako KajiharaHiroo Maeda
    • A61F13/00A61F2/00A61K9/14
    • A61K9/0024A61K47/02
    • The present invention relates to a formulation for implantation having a novel constitution, which accomplishes controlled releases of active ingredients. The formulation comprises one of combinations (a), (b) and (c), as well as a carrier comprising a hydrophobic polymer, wherein the particle combination is dispersed into the carrier: (a) particles comprising an active ingredient, particles comprising a carbonate, and particles comprising a substance which is reacted with the carbonate in an aqueous solution to generate carbon dioxide (substance such as an acid); (b) particles comprising an active ingredient and a carbonate, and particles comprising a substance such as an acid; and (c) particles comprising a carbonate, and particles comprising an active ingredient and a substance such as an acid.
    • 本发明涉及具有实现活性成分控制释放的新颖结构的植入制剂。 制剂包含组合(a),(b)和(c)中的一种,以及包含疏水性聚合物的载体,其中所述颗粒组合分散在载体中:(a)包含活性成分的颗粒, 碳酸盐和包含与碳酸盐在水溶液中反应产生二氧化碳(物质如酸)的物质的颗粒; (b)包含活性成分和碳酸酯的颗粒,以及包含物质如酸的颗粒; 和(c)包含碳酸盐的颗粒和包含活性成分和物质如酸的颗粒。
    • 48. 发明申请
    • SUSTAINED-RELEASE DRUG FORMULATIONS
    • 持续释放药物制剂
    • US20070166377A1
    • 2007-07-19
    • US11688082
    • 2007-03-19
    • Akihiko SanoMasako KajiharaHiroo Maeda
    • Akihiko SanoMasako KajiharaHiroo Maeda
    • A61K39/00A61K9/46
    • A61K9/0024A61K47/02
    • The present invention relates to a formulation for implantation having a novel constitution, which accomplishes controlled releases of active ingredients. The formulation comprises one of combinations (a), (b) and (c), as well as a carrier comprising a hydrophobic polymer, wherein the particle combination is dispersed into the carrier: (a) particles comprising an active ingredient, particles comprising a carbonate, and particles comprising a substance which is reacted with the carbonate in an aqueous solution to generate carbon dioxide (substance such as an acid); (b) particles comprising an active ingredient and a carbonate, and particles comprising a substance such as an acid; and (c) particles comprising a carbonate, and particles comprising an active ingredient and a substance such as an acid.
    • 本发明涉及具有实现活性成分控制释放的新颖结构的植入制剂。 制剂包含组合(a),(b)和(c)中的一种,以及包含疏水性聚合物的载体,其中所述颗粒组合分散在载体中:(a)包含活性成分的颗粒, 碳酸盐和包含与碳酸盐在水溶液中反应产生二氧化碳(物质如酸)的物质的颗粒; (b)包含活性成分和碳酸酯的颗粒,以及包含物质如酸的颗粒; 和(c)包含碳酸盐的颗粒和包含活性成分和物质如酸的颗粒。
    • 49. 发明授权
    • Controlled release preparations having multi-layer structure
    • 具有多层结构的控制释放制剂
    • US07101567B1
    • 2006-09-05
    • US09701303
    • 1999-05-19
    • Akihiko SanoMasako KajiharaToshihiko Sugie
    • Akihiko SanoMasako KajiharaToshihiko Sugie
    • A61F2/00
    • A61K9/209A61K9/0024
    • Preparations whereby two or more drugs can be released separately at appropriate speeds depending on the disease or the release behaviors of one or more drugs can be precisely controlled, which consist of an outer layer wherein a water-soluble drug is dispersed in a carrier made of a biologically non-degradable and hydrophobic polymer material, and one or more inner layers wherein a water-soluble drug, differing in kind or concentration from the one contained in the outer layer, is dispersed in a carrier made of a biologically non-degradable and hydrophobic polymer material, and in which the outer and inner layers are concentrically located in diametral direction of rod-like preparations and both or one of the ends in the axial direction are opened so as to directly come into contact with the environment.
    • 可以精确地控制两种或更多种药物以适当的速度单独释放的制剂,这取决于一种或多种药物的疾病或释放行为,其由外层组成,其中水溶性药物分散在由 生物不可降解和疏水的聚合物材料,以及一种或多种内层,其中与外层中所含的不同种类或浓度的水溶性药物分散在由生物不可降解的载体制成的载体中, 疏水性聚合物材料,并且其中外层和内层同心地位于棒状制剂的直径方向上,并且两个或一个端部沿轴向方向打开以直接与环境接触。
    • 50. 发明申请
    • Supporting structure for cooling jacket of motor/generator
    • 电机/发电机冷却套支撑结构
    • US20060119196A1
    • 2006-06-08
    • US11265160
    • 2005-11-03
    • Masaru KonishiAkihiko SanoYoshitaka Miura
    • Masaru KonishiAkihiko SanoYoshitaka Miura
    • H02K3/24H02K5/18H02K9/00H02K5/20
    • H02K9/19H02K3/24
    • A motor/generator (1) comprises a cylindrical stator core (5) facing the outer periphery of a rotor (3) on the inner side of a case (2). Base plates (8) constituted by an electrical insulation material are laminated on both ends of the stator core (5). A plurality of coils (7) are wound on the laminated body comprising the stator core (5) and the base plates (8). A cooling jacket (6) is attached to each of the base plate (8) using engagement members (6F, 6G, 8D, 8E, 10, 15) in order to envelope the projection of the coil (7). The end planks (2B, 2C) of the case (2) hold and press the cooling jacket (6) toward the stator core (5). Consequently, without forming a flange in order to fix the cooling jacket (6), the cooling jackets (6) are secured at a predetermined position within the case (2).
    • 电动机/发电机(1)包括在壳体(2)内侧面对转子(3)的外周的圆柱形定子铁芯(5)。 由电绝缘材料构成的基板(8)层压在定子铁心(5)的两端。 多个线圈(7)卷绕在包括定子铁芯(5)和基板(8)的层叠体上。 为了包围线圈(7)的突起,使用接合构件(6F,6G,8D,8E,10,15)将冷却套(6)附接到每个基板(8)。 壳体(2)的端板(2B,2C)保持并将冷却套(6)压向定子芯(5)。 因此,为了固定冷却套(6)而不形成凸缘,冷却套(6)固定在壳体(2)内的预定位置。