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    • 44. 发明公开
    • 금속 증착형 다공성 산화 알루미늄 바이오칩 및 그 제조방법
    • 金属多孔阳极铝生物材料及其制备方法
    • KR1020100007723A
    • 2010-01-22
    • KR1020090059184
    • 2009-06-30
    • 한국과학기술원
    • 이상엽박태정김도균
    • G01N33/53C12Q1/00G01N21/17G01N35/00
    • PURPOSE: A porous oxidation aluminum biochip for metal deposition is provided to ensure advantage of the biosensor and detect interaction of various biomolecules with high sensitivity. CONSTITUTION: A porous aluminum biochip for metal deposition comprises: a substrate; an aluminum thin film layer mounted on the substrate; porous oxidation aluminum thin film layer containing plural pores arranged in a specific interval; and metal thin film of LSPR(Localized Surface Plasmon Resonance) mounted on the porous oxidation aluminum thin film. The thickness of the substrate, aluminum thin film layer, and porous oxidation aluminum thin film layer is 0.1-20mm, 30nm-30μm, and 10nm~10μm, respectively. A method for producing the porous oxidation aluminum biochip for metal deposition comprises: a step of forming the aluminum thin film layer on the substrate; a step of treating aluminum thin film layer through anodizing; and a step of forming metal thin film layer on the upper portion of the porous oxidation aluminum thin layer.
    • 目的:提供用于金属沉积的多孔氧化铝生物芯片,以确保生物传感器的优势,并检测各种生物分子与高灵敏度的相互作用。 构成:用于金属沉积的多孔铝生物芯片包括:基底; 安装在基板上的铝薄膜层; 多孔氧化铝薄膜层,其具有以特定间隔排列的多个孔; 和金属薄膜的LSPR(局部表面等离子体共振)安装在多孔氧化铝薄膜上。 基板,铝薄膜层和多孔氧化铝薄膜层的厚度分别为0.1-20mm,30nm-30μm和10nm〜10μm。 用于金属沉积的多孔氧化铝生物芯片的制造方法包括:在所述基板上形成所述铝薄膜层的工序; 通过阳极氧化处理铝薄膜层的步骤; 以及在多孔氧化铝薄层的上部形成金属薄膜层的工序。
    • 45. 发明公开
    • 전도성 그라핀을 이용한 바이오센서 및 그 제조방법
    • 使用导电石墨的生物传感器及其制造方法
    • KR1020100001062A
    • 2010-01-06
    • KR1020080060813
    • 2008-06-26
    • 한국과학기술원
    • 이상엽박태정홍원희정희태박호석최봉길
    • C01B31/02C01B31/04G01N33/53G01N33/48
    • G01N33/5438B82Y30/00B82Y40/00C01B32/194C12Q1/004G01N27/308G01N27/3335
    • PURPOSE: A biosensor using conductive graphene and a manufacturing method thereof are provided to offer good conductivity, and to increase detection sensitivity of biological molecules with a small amount of sources. CONSTITUTION: A manufacturing method of conductive graphene includes a step for manufacturing the graphene having a carboxyl group and a step for manufacturing the graphene reformed to a thiol group by combining the carboxyl group with an amino group of chemical materials having an amino group and the thiol group at the same time. A method for manufacturing a conductive graphene film includes the following steps of: manufacturing a substrate in which the thiol group is exposed; attaching the conductive graphene on the substrate by combining the thiol group with the conductive graphene; laminating the conductive graphenes by combining the attached conductive graphenes to the conductive graphenes; and enhancing the density of the conductive graphenes.
    • 目的:提供使用导电石墨烯的生物传感器及其制造方法,以提供良好的导电性,并且增加具有少量源的生物分子的检测灵敏度。 构成:导电石墨烯的制造方法包括制造具有羧基的石墨烯的步骤和通过将羧基与具有氨基的化学物质的氨基和硫醇组合而制造重整为硫醇基的石墨烯的步骤 同时组。 制造导电石墨烯膜的方法包括以下步骤:制造其中暴露硫醇基团的基板; 通过组合硫醇基与导电石墨烯将导电石墨烯附着在基片上; 通过将附着的导电石墨烯与导电石墨烯组合来层压导电石墨烯; 并提高导电石墨烯的密度。
    • 47. 发明公开
    • 시료의 미세혼합장치 및 이를 포함하는 랩온어칩
    • 样品的微混合装置和包含上述装置的片上薄片
    • KR1020070122415A
    • 2007-12-31
    • KR1020070062941
    • 2007-06-26
    • 한국과학기술원
    • 홍원희이상엽김도현홍연기허윤석박태정양광석이은주
    • G01N33/50G01N33/48G01N33/483
    • A micro-mixing device of samples is provided to simplify the device and improve the mixing efficiency and rapidness, so that the device realizes various lab-on-a-chips in combination with various micro-analysis devices. A micro-mixing device of samples comprises: a sample-mixing chamber equipped with a magnetic disc which is operated by the magnetic field; and an inlet and an outlet which are connected to both ends of the sample-mixing chamber, respectively, wherein the device further comprises an analysis chamber for analysis of mixing efficiency of samples between the sample-mixing chamber and the outlet and the magnetic disc is impregnated into a polymer film of polydimethyl siloxane. A lab-on-a-chip contains the micro-mixing device of samples and a solid phase extraction device connected to the micro-mixing device, which is packed with polymer solid phase-extracting agents through in-situ polymerization.
    • 提供样品的微混合装置以简化装置并提高混合效率和快速性,使得该装置与各种微分析装置结合实现各种实验室上的芯片。 样品的微混合装置包括:装有由磁场操作的磁盘的样品混合室; 以及分别与样品混合室的两端连接的入口和出口,其中所述装置还包括分析室,用于分析样品混合室和出口之间的样品的混合效率,并且磁盘为 浸渍在聚二甲基硅氧烷的聚合物膜中。 芯片实验室包含样品的微混合装置和连接到微混合装置的固相萃取装置,其通过原位聚合装入聚合物固相萃取剂。