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41. 发明申请

WO2009089372A3 SYSTEMS AND METHODS FOR ANALYSIS AND TREATMENT OF A BODY LUMEN 审中-公开
标题翻译：体温分析与处理系统与方法
公开(公告)号：WO2009089372A3
公开(公告)日：2009-10-08
申请号：PCT/US2009030467
申请日：2009-01-08
申请人： CORNOVA INC , TANG JING , RYAN S ERIC
发明人： TANG JING , RYAN S ERIC
IPC分类号： A61F2/958 , A61M31/00
CPC分类号： A61B5/6852 , A61B5/0066 , A61B5/0071 , A61B5/0075 , A61B5/0084 , A61B5/0086 , A61B5/02007 , A61B5/14539 , A61B5/6853 , A61B6/12 , A61B2017/22001 , A61B2018/00345 , A61B2018/00386 , A61B2018/00404 , A61B2018/00577 , A61B2018/00982 , A61B2562/0242 , A61F2/958 , A61M25/1011 , A61M25/1027 , A61M25/104 , A61M29/02 , A61M2025/1079 , A61M2025/1088
摘要： A catheter is provided for placement within a body lumen, the catheter including a flexible conduit that is elongated along a longitudinal axis, the flexible conduit having a proximal end and a distal end. The catheter further includes at least one delivery waveguide and at least one collection waveguide positioned along the flexible conduit, the at least one delivery waveguide and the at least one collection waveguide constructed and arranged to transmit radiation at a wavelength in a range of about 250 to 2500 nanometers. The catheter further includes a flexible, expandable first surface encircling surrounding a segment of the conduit, a transmission output of the at least one delivery waveguide and a transmission input of the at least one collection waveguide located within the flexible, expandable first surface, and the distal end of at least one of the at least one delivery waveguide and the at least one collection waveguide tethered to the flexible, expandable first surface radially translatable with respect to the flexible, expandable first surface, the at least one transmission input located between a portion of the flexible, expandable first surface and a portion of the second surface.
摘要翻译：提供用于放置在体腔内的导管，所述导管包括沿着纵向轴线细长的柔性导管，所述柔性导管具有近端和远端。所述导管还包括至少一个输送波导和至少一个沿着柔性导管定位的收集波导，所述至少一个输送波导和所述至少一个收集波导被构造和布置成将波长在约250〜 2500纳米。所述导管还包括围绕所述导管段的柔性可扩张第一表面，所述至少一个输送波导的透射输出和位于所述柔性可扩张第一表面内的所述至少一个收集波导的透射输入，所述至少一个输送波导中的至少一个的至少一个远端和所述至少一个收集波导束缚于所述柔性可扩张第一表面，所述第一表面可相对于所述柔性可扩张第一表面径向平移，所述至少一个传输输入位于所述至少一个的柔性可扩张的第一表面和第二表面的一部分。

42. 发明申请

WO2009089372A9 SYSTEMS AND METHODS FOR ANALYSIS AND TREATMENT OF A BODY LUMEN 审中-公开
公开(公告)号：WO2009089372A9
公开(公告)日：2009-07-16
申请号：PCT/US2009/030467
申请日：2009-01-08
申请人： CORNOVA, INC. , TANG, Jing , RYAN, S. Eric
发明人： TANG, Jing , RYAN, S. Eric
IPC分类号： A61M25/10 , A61M31/00
摘要： A catheter is provided for placement within a body lumen, the catheter including a flexible conduit that is elongated along a longitudinal axis, the flexible conduit having a proximal end and a distal end. The catheter further includes at least one delivery waveguide and at least one collection waveguide positioned along the flexible conduit, the at least one delivery waveguide and the at least one collection waveguide constructed and arranged to transmit radiation at a wavelength in a range of about 250 to 2500 nanometers. The catheter further includes a flexible, expandable first surface encircling surrounding a segment of the conduit, a transmission output of the at least one delivery waveguide and a transmission input of the at least one collection waveguide located within the flexible, expandable first surface, and the distal end of at least one of the at least one delivery waveguide and the at least one collection waveguide tethered to the flexible, expandable first surface radially translatable with respect to the flexible, expandable first surface, the at least one transmission input located between a portion of the flexible, expandable first surface and a portion of the second surface.

43. 发明申请

WO2009089364A2 SHAPED FIBER ENDS AND METHODS OF MAKING SAME 审中-公开
标题翻译：形状纤维端及其制造方法
公开(公告)号：WO2009089364A2
公开(公告)日：2009-07-16
申请号：PCT/US2009/030457
申请日：2009-01-08
申请人： CORNOVA, INC. , TANG, Jing
发明人： TANG, Jing
IPC分类号： A61M25/10 , A61L33/00
CPC分类号： A61M25/104 , A61B5/0066 , A61B5/0075 , A61B5/0084 , A61B5/0086 , A61B5/02007 , A61B5/6852 , A61B6/12 , A61B2017/22001 , A61B2018/00345 , A61B2018/00386 , A61B2018/00404 , A61B2018/00577 , A61B2018/00982 , A61B2018/2272 , A61F2/958 , A61M25/1011 , A61M25/1027 , A61M29/02 , A61M2025/1079 , A61M2025/1088 , C03C25/68 , G02B6/0281 , G02B6/262
摘要： An optical fiber tip comprises a core and a recess formed in said core at a distal end of the optical fiber tip, said recess having a vertex within said core.
摘要翻译：光纤尖端包括芯部和在光纤末端的远端处形成在所述芯部中的凹部，所述凹部在所述芯部内具有顶点。

44. 发明申请

WO2008051197A2 SMALL-MOLECULE BOTULINUM TOXIN INHIBITORS 审中-公开
标题翻译：小分子氧化铁抑制剂
公开(公告)号：WO2008051197A2
公开(公告)日：2008-05-02
申请号：PCT/US2006/036710
申请日：2006-09-20
申请人： MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH , GOVERNMENT OF THE UNITED STATES, AS REPRESENTED BY THE SECRETARY OF THE ARMY, ON BEHALF OF THE U.S. , PANG, Yuan-ping , MILLARD, Charles B. , PARK, Jewn Giew , TANG, Jing , SCHMIDT, James J.
发明人： PANG, Yuan-ping , MILLARD, Charles B. , PARK, Jewn Giew , TANG, Jing , SCHMIDT, James J.
IPC分类号： G21C13/02
CPC分类号： A61K31/675
摘要： Small-molecule inhibitors of Botulinum toxin, including BoNTA, BoNTD and BoNTE are provided, as well as methods of using the inhibitors.
摘要翻译：提供了肉毒杆菌毒素的小分子抑制剂，包括BoNTA，BoNTD和BoNTE，以及使用抑制剂的方法。

45. 发明申请

WO2007041542A3 SYSTEMS AND METHODS FOR ANALYSIS AND TREATMENT OF A BODY LUMEN 审中-公开
标题翻译：用于分析和治疗体液的系统和方法
公开(公告)号：WO2007041542A3
公开(公告)日：2007-11-15
申请号：PCT/US2006038547
申请日：2006-09-29
申请人： CORNOVA INC , RYAN ERIC S , TANG JING
发明人： RYAN ERIC S , TANG JING
IPC分类号： A61B5/00 , A61F2/06 , A61M25/10
CPC分类号： A61B5/6852 , A61B5/0066 , A61B5/0071 , A61B5/0075 , A61B5/0084 , A61B5/0086 , A61B5/01 , A61B5/015 , A61B5/02007 , A61B5/6853 , A61B2017/22001 , A61N5/0601
摘要： In a system and method for analyzing and treating a body lumen, a lumen-expanding balloon catheter with integrated one or more delivery waveguides and one or more collection waveguides is used to perform optical analysis of the tissues surrounding the lumen during expansion. The catheter can comprise an angioplasty catheter with integrated delivery waveguides and collection waveguides to perform spectroscopy of a stenotic plaque during angioplasty.
摘要翻译：在用于分析和处理体腔的系统和方法中，具有集成的一个或多个传送波导和一个或多个收集波导的内腔扩张球囊导管用于在扩张期间对内腔周围的组织进行光学分析。导管可以包括血管成形术导管，其具有集成的递送波导和收集波导以在血管成形术期间执行狭窄斑块的光谱学。

46. 发明申请

WO2003062826A2 MATERIALS AND METHODS FOR TREATING CANCER 审中-公开
标题翻译：用于治疗癌症的材料和方法
公开(公告)号：WO2003062826A2
公开(公告)日：2003-07-31
申请号：PCT/GB2003/000329
申请日：2003-01-23
申请人： BIOTECH RESEARCH VENTURES PTE LIMITED , CRIPPS, Joanna, E. , NG, Aylwin , TANG, Jing, P. , HUI, Kam, M. , GOH, Christopher, H., K.
发明人： NG, Aylwin , TANG, Jing, P. , HUI, Kam, M. , GOH, Christopher, H., K.
IPC分类号： G01N33/574
CPC分类号： G01N33/6872 , C12Q1/6827 , C12Q1/6886 , C12Q2600/112 , C12Q2600/136 , C12Q2600/154 , G01N33/57407 , G01N33/57496 , G01N33/6863 , G01N2500/10 , C12Q2523/125
摘要： The invention is concerned with the detection and treatment of nasopharyngeal carcinoma (NPC) based on differential gene expression in these cells. Specifically, the invention provides details of differentially expressed genes in NPC which serve to detect the presence or risk of the disease and its clinical type. The invention also provides methods of treating NPC in association with chemo or radiotherapy.
摘要翻译：本发明涉及基于这些细胞中差异基因表达的鼻咽癌（NPC）的检测和治疗。具体而言，本发明提供了NPC中差异表达基因的细节，其用于检测疾病的存在或风险及其临床类型。本发明还提供了与化疗或放疗相关的治疗NPC的方法。

47. 发明申请

WO2002096484A2 APPARATUS AND METHOD FOR THE OPTICAL IMAGING OF TISSUE SAMPLES 审中-公开
标题翻译：用于组织样品的光学成像的装置和方法
公开(公告)号：WO2002096484A2
公开(公告)日：2002-12-05
申请号：PCT/US2002/017202
申请日：2002-05-30
申请人： INFRAREDX, INC. , TANG, Jing , RYAN, S. Eric , BOUMA, Brett, E. , TEARNEY, Guillermo, J. , FURNISH, Simon , ZULUAGA, Andres
发明人： TANG, Jing , RYAN, S. Eric , BOUMA, Brett, E. , TEARNEY, Guillermo, J. , FURNISH, Simon , ZULUAGA, Andres
IPC分类号： A61M
CPC分类号： A61B5/0084
摘要： A catheter based optical system for generating data as to the condition of a tissue sample of a mammalian vessel. The system includes an elongated catheter shaft having a tissue engaging distal end and a coupled proximal end and an elongated optical delivery fiber arrangement disposed through a lumen of said catheter, said optical delivery fiber arrangement having a distal end and a proximal end. The distal end of the delivery fiber arrangement has a re-director light emitter thereon for directing light against mammalian tissues. An elongated optical collection fiber arrangement is disposed through a lumen of the catheter, the optical collection fiber arrangement having distal end and a proximal most end. The distal end of the collection fiber arrangement has a re-director light receiver thereon for receiving light reflected from the mammalian tissue by the light emitter. The light emitter and the light receiver are longitudinally space apart from one another in the distal end of the catheter. The catheter apparatus includes a light source in communication with the delivery fiber and a signal detector in communication with the receiving fiber for receiving and presenting data collected.
摘要翻译：一种用于产生关于哺乳动物血管（W）的组织样本的状况的数据的基于导管的光学系统（10）。该系统包括具有组织接合远端（18）和耦合的近端（20）的细长导管轴（16）和通过所述导管（16）的内腔设置的细长的光学输送纤维布置（24），所述光学具有远端（28）和近端（32）的输送纤维布置（24）。输送纤维布置（28）的远端在其上具有引导光发射器（30），用于将光引导到哺乳动物组织（W）上。细长的光学收集纤维布置（26）穿过导管（16）的内腔设置，光学收集纤维布置（26）具有远端（34）和最近端（36）。收集纤维布置（34）的远端在其上具有重新引导光接收器（30），用于接收由光发射器（30）从哺乳动物组织（W）反射的光。光发射器（42）和光接收器（40）在导管（18）的远端中彼此分开的纵向空间（d）。导管装置包括与输送光纤（24）通信的光源（12）和与接收光纤（26）通信的用于接收和呈现收集的数据的信号（50）。

48. 发明申请

WO2002096479A3 BALLOON CATHETER 审中-公开
公开(公告)号：WO2002096479A3
公开(公告)日：2002-12-05
申请号：PCT/US2002/015118
申请日：2002-05-14
申请人： INFRAREDX, INC. , RYAN, S., Eric , BOUMA, Brett, E. , TEARNEY, Guillermo, J. , FURNISH, Simon , TANG, Jing , ZULUAGA, Andres
发明人： RYAN, S., Eric , BOUMA, Brett, E. , TEARNEY, Guillermo, J. , FURNISH, Simon , TANG, Jing , ZULUAGA, Andres
IPC分类号： A61M29/00
摘要： An apparatus includes a feedback loop for controlling an extent of a gap (40) between a wall of a balloon (18) mounted on a catheter (12) and a wall (38) of a lumen (36) into which the catheter (12) is inserted. The apparatus includes a radiation detector (28) mounted within the balloon (18) for generating a feedback signal having information indicative of whether the extent of the gap (40) is greater than or less than a desired value. The feedback loop receives the feedback signal and controls a size of the balloon (18) to cause the extent of the gap (40) to approach the desired value.

49. 发明申请

WO2014194199A1 METHODS FOR MANGANESE NITRIDE INTEGRATION 审中-公开
标题翻译：万方数据集成方法
公开(公告)号：WO2014194199A1
公开(公告)日：2014-12-04
申请号：PCT/US2014/040239
申请日：2014-05-30
申请人： APPLIED MATERIALS, INC. , MA, Paul, F. , TSENG, Jennifer, Meng , CHANG, Mei , LAKSHMANAN, Annamalai , TANG, Jing
发明人： MA, Paul, F. , TSENG, Jennifer, Meng , CHANG, Mei , LAKSHMANAN, Annamalai , TANG, Jing
IPC分类号： H01L21/318 , H01L21/205 , H01L21/203
CPC分类号： H01L21/321 , H01L21/28562 , H01L21/76831 , H01L21/76846 , H01L21/76856 , H01L23/53238 , H01L2924/0002 , H01L2924/00
摘要： Described are methods of forming a semiconductor device. Certain methods comprises depositing a film comprising manganese nitride over a dielectric; depositing a copper seed layer over the film; and depositing a copper fill layer over the copper seed layer. Also described are semiconductor devices. Certain semiconductor devices comprise a low-k dielectric layer; a manganese nitride layer overlying the low-k dielectric layer; a seed layer selected from a copper seed layer or electrochemical deposition seed layer overlying the manganese nitride layer; a copper layer overlying the copper seed layer.
摘要翻译：描述了形成半导体器件的方法。某些方法包括在电介质上沉积包含氮化锰的膜; 在该膜上沉积铜种子层; 以及在铜种子层上沉积铜填充层。还描述了半导体器件。某些半导体器件包括低k电介质层; 覆盖低k电介质层的氮化锰层; 选自铜籽晶层或覆盖氮化锰层的电化学沉积种子层的晶种层; 覆铜层的铜层。

50. 发明申请

WO2013049173A3 IMPROVED INTRENCH PROFILE 审中-公开
标题翻译：改进的英语资料
公开(公告)号：WO2013049173A3
公开(公告)日：2013-06-13
申请号：PCT/US2012057294
申请日：2012-09-26
申请人： APPLIED MATERIALS INC , SAPRE KEDAR , INGLE NITIN K , TANG JING
发明人： SAPRE KEDAR , INGLE NITIN K , TANG JING
IPC分类号： H01L21/762 , H01L21/205 , H01L21/31
CPC分类号： H01L21/3065 , H01L21/3081 , H01L21/76224
摘要： A method of etching a recess in a semiconductor substrate is described. The method may include forming a dielectric liner layer in a trench of the substrate where the liner layer has a first density. The method may also include depositing a second dielectric layer at least partially in the trench on the liner layer. The second dielectric layer may initially be flowable following the deposition, and have a second density that is less than the first density of the liner. The method may further include exposing the substrate to a dry etchant, where the etchant removes a portion of the first liner layer and the second dielectric layer to form a recess, where the dry etchant includes a fluorine-containing compound and molecular hydrogen, and where the etch rate ratio for removing the first dielectric liner layer to removing the second dielectric layer is about 1:1.2 to about 1:1.
摘要翻译：描述了蚀刻半导体衬底中的凹陷的方法。该方法可以包括在衬底的具有第一密度的衬底的沟槽中形成电介质衬里层。该方法还可以包括至少部分地在衬垫层上的沟槽中沉积第二介电层。第二介电层在沉积之后最初可以是可流动的，并且具有小于衬里的第一密度的第二密度。该方法可进一步包括将衬底暴露于干蚀刻剂，其中蚀刻剂去除第一衬层和第二介电层的一部分以形成凹槽，其中干蚀刻剂包括含氟化合物和分子氢，并且其中用于去除第一电介质衬垫层以去除第二电介质层的蚀刻速率比为约1：1.2至约1：1。

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