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    • 47. 发明申请
    • VALVE PROSTHESIS SYSTEMS AND METHODS
    • 阀门预测系统和方法
    • WO2008103497A3
    • 2009-12-30
    • PCT/US2008050096
    • 2008-01-03
    • ENDOVALVE INCUNIV PENNSYLVANIALAMPHERE DAVID GNGUYEN TUAN ANHHERRMANN HOWARD C
    • LAMPHERE DAVID GNGUYEN TUAN ANHHERRMANN HOWARD C
    • A61F2/24
    • A61F2/2412A61F2/243A61F2/2436A61F2/2439
    • Valve prostheses are disclosed that are adapted for secure and aligned placement relative to a heart annulus. The valve prosthesis may include a resilient ring, a plurality of leaflet membranes mounted with respect to the resilient ring, and a plurality of positioning elements movably mounted with respect to the flexible ring, each of the positioning elements defining a first tissue engaging region and a second tissue engaging region spaced from the first tissue engaging region. The positioning elements are adapted to substantially completely invert by rotating relative to the resilient ring between a first position in which each of the first and second tissue engaging regions is inwardly directed for facilitating positioning of the valve prosthesis within a delivery catheter, and a second position In which each of the first and second tissue engaging regions is outwardly directed for engaging tissue.
    • 公开了适于相对于心脏环的安全和对准放置的阀门假体。 瓣膜假体可以包括弹性环,相对于弹性环安装的多个小叶膜和相对于柔性环可移动地安装的多个定位元件,每个定位元件限定第一组织接合区域和 第二组织接合区域与第一组织接合区域间隔开。 定位元件适于在第一位置和第二位置之间通过相对于弹性环的旋转基本上完全反转,在第一位置中,第一和第二组织接合区域中的每一个向内指向,以便于将瓣膜假体定位在输送导管内, 其中第一和第二组织接合区域中的每一个向外指向用于接合组织。
    • 49. 发明申请
    • VALVE PROSTHESIS SYSTEMS AND METHODS
    • 阀门预测系统和方法
    • WO2008103497A2
    • 2008-08-28
    • PCT/US2008/050096
    • 2008-01-03
    • ENDOVALVE, INC.THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIALAMPHERE, David, G.NGUYEN, Tuan, AnhHERRMANN, Howard, C.
    • LAMPHERE, David, G.NGUYEN, Tuan, AnhHERRMANN, Howard, C.
    • A61F2/24
    • A61F2/2412A61F2/243A61F2/2436A61F2/2439
    • Valve prostheses are disclosed that are adapted for secure and aligned placement relative to a heart annulus. The valve prostheses may be placed in a non-invasive manner, e.g., via trans-catheter techniques, and may be positioned/repositioned until proper alignment and positioning is achieved. The valve prosthesis may include a resilient ring, a plurality of leaflet membranes mounted with respect to the resilient ring, and a plurality of positioning elements movably mounted with respect to the flexible ring, each of the positioning elements defining a first tissue engaging region and a second tissue engaging region spaced from the first tissue engaging region. The positioning elements are adapted to substantially completely invert by rotating relative to the resilient ring between a first position in which each of the first and second tissue engaging regions is inwardly directed for facilitating positioning of the valve prosthesis within a delivery catheter, and a second position in which each of the first and second tissue engaging regions is outwardly directed for engaging tissue. The valve prosthesis may also include a valve skirt mounted with respect to the resilient ring.
    • 公开了适于相对于心脏环的安全和对准放置的阀门假体。 瓣膜假体可以以非侵入性方式放置,例如经由导管技术,并且可以定位/重新定位,直到实现适当的对准和定位。 瓣膜假体可以包括弹性环,相对于弹性环安装的多个小叶膜和相对于柔性环可移动地安装的多个定位元件,每个定位元件限定第一组织接合区域和 第二组织接合区域与第一组织接合区域间隔开。 定位元件适于在第一位置和第二位置之间通过相对于弹性环的旋转基本上完全反转,在第一位置中,第一和第二组织接合区域中的每一个向内指向,以便于将瓣膜假体定位在输送导管内, 其中第一和第二组织接合区域中的每一个向外指向用于接合组织。 瓣膜假体还可以包括相对于弹性环安装的阀裙。