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41. 发明申请

WO2009039093A2 A RADIO FREQUENCY ENERGY TRANSMISSION DEVICE FOR THE ABLATION OF BIOLOGICAL TISSUES 审中-公开
标题翻译：用于消除生物组织的无线电频率能量传输装置
公开(公告)号：WO2009039093A2
公开(公告)日：2009-03-26
申请号：PCT/US2008/076523
申请日：2008-09-16
申请人： MEDWAVES, INC. , ORMSBY, Theodore C. , LEUNG, George L. , LAW, Ming Fan
发明人： ORMSBY, Theodore C. , LEUNG, George L. , LAW, Ming Fan
IPC分类号： A61B18/18
CPC分类号： A61B18/14 , A61B18/18 , A61B18/1815 , A61B2017/00243 , A61B2018/00577 , H01Q11/08
摘要： A radio frequency energy transmission device comprises a hollow coaxial electrically conductive cable which conducts radio frequency (RF) energy, particularly microwave energy, for the ablation of biological tissue. Coaxial inner and outer conductors extend substantially the entire length of the cable from the proximal end to a distal end portion of the cable. The inner conductor comprises a tubular member having a hollow, axially extending lumen, and the outer conductor comprises a tubular member disposed in a substantially coaxial relationship over at least a portion of the inner conductor. Dielectricity to impede conduction between the inner and outer conductors is introduced with a vacuum or dielectric medium disposed between the inner and outer conductors. An ablating member, which delivers radio frequency energy to body tissue is disposed at a distal end portion of the cable. The ablating member can be a helical coil, a monopole or a microstrip circuit.
摘要翻译：无线电频率能量传输装置包括中空的同轴导电电缆，其传导射频（RF）能量，特别是微波能量，用于生物组织的消融。同轴的内部和外部导体基本上从电缆的近端延伸到电缆的远端部分的整个长度。内导体包括具有中空轴向延伸的内腔的管状构件，并且外导体包括在内导体的至少一部分上基本上共轴的关系设置的管状构件。导电内阻和外导体之间的导通电介质被设置在内导体和外导体之间的真空或电介质介质。将电波能量传递到身体组织的消融部件设置在电缆的远端部分。烧蚀构件可以是螺旋线圈，单极或微带电路。

42. 发明申请

WO2005016119A3 RADIO-FREQUENCY BASED CATHETER SYSTEM AND METHOD FOR ABLATING BIOLOGICAL TISSUES 审中-公开
标题翻译：基于无线电频率的导管系统及其生物组织研究方法
公开(公告)号：WO2005016119A3
公开(公告)日：2005-12-01
申请号：PCT/US2004024696
申请日：2004-07-30
申请人： MEDWAVES INC , ORMSBY THEODORE C , LAW MING-FAN , LEUNG GEORGE L
发明人： ORMSBY THEODORE C , LAW MING-FAN , LEUNG GEORGE L
IPC分类号： A61B20060101 , A61B18/04 , A61B18/14
CPC分类号： A61B18/1492 , A61B18/18 , A61B90/39 , A61B2017/003 , A61B2018/00214 , A61B2018/00839 , A61B2018/00875 , A61B2018/1407 , A61B2018/1437
摘要： An improved radio-frequency based catheter system and method for ablating biological tissues within the body vessel of a patient comprises a radio-frequency ("RF") generator for selectively generating high frequency energy in a deployable catheter having a RF co-axial transmission line with a hollow lumen, a RF antenna mounted on the distal portion of the catheter, and steering control lines in the lumen of the transmission line for steering catheter while being inserted into the body vessel and for deflecting the RF antenna to accommodate the contour of the body vessel where tissue ablation is needed.
摘要翻译：改进的基于射频的导管系统和用于消除患者体内血液中生物组织的方法包括：射频（“RF”）发生器，用于在具有RF同轴传输线的可展开导管中选择性地产生高频能量具有中空管腔，安装在导管的远端部分上的RF天线以及用于转向导管的传输线的内腔中的转向控制线，同时插入到身体容器中并用于偏转RF天线以适应需要组织消融的身体血管。

43. 发明申请

WO2004073766A3 PREFORMED CATHETER FOR LINEAR ATRIAL ABLATION 审中-公开
标题翻译：线性ATRIAL ABLATION的预制导管
公开(公告)号：WO2004073766A3
公开(公告)日：2005-01-20
申请号：PCT/US2004004693
申请日：2004-02-19
申请人： MEDWAVES INC , FELD GREGORY K , ORMSBY THEODORE C , LAW MING-FAN , LEUNG GEORGE L
发明人： FELD GREGORY K , ORMSBY THEODORE C , LAW MING-FAN , LEUNG GEORGE L
IPC分类号： A61B18/14 , A61B18/18
CPC分类号： A61B18/1492 , A61B2018/183
摘要： A preformed catheter set for production of linear ablation lines in the left and right atrium for treatment of atrial fibrillation includes at least a first catheter including a pre-shaped distal segment having a distal linear ablation antenna and a U-shaped curve portion proximal to the distal linear ablation antenna.
摘要翻译：用于在左心房和右心房中产生线性消融线的预成型导管套件用于治疗房颤包括至少第一导管，其包括具有远端线性消融天线的预形远端区段和靠近该房间的U形曲线部分远端线性消融天线。

44. 发明申请

WO2003047448A1 RADIO-FREQUENCY-BASED CATHETER SYSTEM WITH IMPROVED DEFLECTION AND STEERING MECHANISMS 审中-公开
标题翻译：具有改进的偏转和转向机构的无线电频率导管系统
公开(公告)号：WO2003047448A1
公开(公告)日：2003-06-12
申请号：PCT/US2002/037886
申请日：2002-11-27
申请人： MEDWAVES, INC.
发明人： ORMSBY, Theodore, C. , LAW, Ming-Fan , LEUNG, George, L.
IPC分类号： A61B18/18
CPC分类号： H01Q1/42 , A61B18/1492 , A61B2017/003 , A61B2017/00867 , A61B2018/00357 , A61B2018/00839 , C08L2201/12
摘要： A shapeable curvilinear radio-frequency antenna apparatus (110) for ablating biological tissue within the body vessel of a patient includes a flexible catheter body (120) having a distal portion (140) and an elongated lumen (150). Inner and outer coaxially aligned conductors (640, 660) extend within the catheter (120) and are coaxial with the lumen (150). A flexible shapeable curvilinear radio-frequency antenna (250) is carried by the distal portion of the flexible catheter body (120) and is in electrical communication with the inner and outer coaxially aligned conductors (640, 660). The flexible shapeable curvilinear radio-frequency antenna (250) is adaptable to receive and transmit radio-frequency energy for ablating biological tissue and is shapeable between a straight configuration (190) and a curvilinear configuration (180) for creating a curvilinear ablation pattern in biological tissue within the body vessel of a patient.
摘要翻译：一种用于消除患者体内容器内生物组织的可变形曲线射频天线装置，包括具有远侧部分（140）和细长腔（150）的柔性导管主体（120）。内部和外部同轴对准的导体（640,660）在导管（120）内延伸并且与内腔（150）同轴。灵活的可变形的曲线射频天线（250）由柔性导管主体（120）的远端部分承载，并且与内部和外部同轴对准的导体（640,660）电连通。柔性可变形曲线射频天线（250）适于接收和发送用于烧蚀生物组织的射频能量，并且可在直线构型（190）和曲线构型（180）之间成形，用于在生物体中形成曲线消融图案患者体内的组织。

45. 发明授权

EP2419040B1 RF ABLATION SYSTEM COMPRISING A DIELECTRIC TRANSFORMER 有权
标题翻译：用介电变压器的高频消融
公开(公告)号：EP2419040B1
公开(公告)日：2014-06-11
申请号：EP10765195.2
申请日：2010-04-15
申请人： Medwaves, Inc.
发明人： ORMSBY, Theodore , CHUNG, Russell , LEUNG, George , SHEN, Gwo Jenn
IPC分类号： A61B18/18 , A61B17/3205
CPC分类号： A61B18/18 , A61B18/1815 , A61B2018/1853 , A61B2018/1869

46. 发明公开

EP2419040A2 RADIO FREQUENCY BASED ABLATION SYSTEM AND METHOD WITH DIELECTRIC TRANSFORMER 有权
标题翻译：用介电变压器的高频消融
公开(公告)号：EP2419040A2
公开(公告)日：2012-02-22
申请号：EP10765195.2
申请日：2010-04-15
申请人： Medwaves, Inc.
发明人： ORMSBY, Theodore , CHUNG, Russell , LEUNG, George , SHEN, Gwo Jenn
IPC分类号： A61B18/18 , A61B17/3205
CPC分类号： A61B18/18 , A61B18/1815 , A61B2018/1853 , A61B2018/1869
摘要： An ablation device which transmits radio frequency (RF) energy for the ablation of biological tissues has elongate inner and outer coaxial conductors extending from a proximal portion to a distal portion. An RF antenna is disposed at the distal portion of the device and transmits RF energy for ablation of a tissue region to be treated. Reflection of energy from the tissue or the ablation point is reduced by providing multiple layers of dielectric media about the antenna, or by providing a gradual transition point from the conductors to the antenna tip, by means of a longitudinally stepped dielectric layer transformer.

47. 发明公开

EP1568331A1 Radio-frequency based catheter system and hollow co-axial cable for ablation of body tissues 有权
标题翻译： Hochfrequenzkatheter mit koaxialem Hohlkabel zur Ablation vonKörpergewebe
公开(公告)号：EP1568331A1
公开(公告)日：2005-08-31
申请号：EP05011329.9
申请日：1999-12-08
申请人： Medwaves, Inc.
发明人： Ormsby, Theodore C , Leung, George L , Law, Ming-Fan
IPC分类号： A61B18/14
CPC分类号： A61B18/18 , A61B18/1492 , A61B18/1815 , A61B90/39 , A61B2017/003 , A61B2018/00839 , A61B2018/1407 , A61B2018/1437 , A61B2018/1861
摘要： A method of ablating body tissue using a catheter which has an ablating element to deliver radio-frequency frequency energy to body tissue and an electrical hollow cable to conduct radio-frequency energy between a radio-frequency energy source and the ablating element. The electrical hollow cable used has first and second coaxial elongate electrically conductive tubular members coupled to the ablating element. A tubular dielectric member is disposed between the first and second tubular members without an air gap therebetween. There is an axial lumen through which the deployable guide is slidably received. In the method, the ablating member is deployed out of the catheter by eliding the electrical hollow cable over the deployable guide; and the body tissue is ablated with the ablating element.
摘要翻译：一种使用具有用于向人体组织输送射频频率能量的消融元件和电中空电缆以在射频能量源和消融元件之间传导射频能量的导管来消除身体组织的方法。所使用的电中空电缆具有联接到烧蚀元件的第一和第二同轴细长导电管状构件。管状电介质构件设置在第一和第二管状构件之间，其间没有气隙。有一个轴向内腔，可展开的引导件通过该轴向腔被可滑动地接收。在该方法中，通过在可展开引导件上方穿过电中空电缆将消融部件从导管部署出来; 并且用烧蚀元件烧蚀身体组织。

48. 发明授权

EP1054639B8 RADIO-FREQUENCY BASED CATHETER SYSTEM FOR ABLATION OF BODY TISSUES 有权
标题翻译：高频率对于身体组织的消融
公开(公告)号：EP1054639B8
公开(公告)日：2005-08-03
申请号：EP99965180.5
申请日：1999-12-08
申请人： Medwaves, Inc.
发明人： Ormsby, Theodore C. , Leung, George L. , Law, Ming-Fan
IPC分类号： A61B18/12 , H01B11/18
CPC分类号： A61B18/18 , A61B18/1492 , A61B18/1815 , A61B90/39 , A61B2017/003 , A61B2018/00839 , A61B2018/1407 , A61B2018/1437 , A61B2018/1861
摘要： An improved radio frequency catheter system for ablating biological tissues of body vessel in a patient including a catheter (3), a deployable antenna guide (36) disposed at the distal portion of the catheter, and a radio-frequency ('RF') antenna (54) mounted on the antenna guide. The RF antenna includes an axial passageway to accommodate the antenna guide, is adapted to receive, and transmit RF energy for tissue ablation. Upon deployment, the antenna guide acquires a loop configuration which establishes line contact with the body vessel conformable to its internal contour to prescribe the precise, and affixed tissue ablation pathway despite body vessel movements. The RF antenna is carried by the antenna guide to be deployed along the established tissue ablation pathway. Alignment of the loop with the desired tissue ablation pathway is facilitated with the use of radiopaque markers, and intra-cardiac electrodes mounted along the antenna guide. The catheter, as well as the antenna, can be provided with steering or deflection mechanism for navigation through the body vessel passageways. A hollow coaxial cable is provided for the delivery of RF energy.

49. 发明授权

EP2073738B1 ABLATION CATHETER APPARATUS WITH ONE OR MORE ELECTRODES 有权
标题翻译：与一个或多个电极ABLATIONSKATHETERVORRICHTUNG
公开(公告)号：EP2073738B1
公开(公告)日：2015-06-10
申请号：EP07853876.6
申请日：2007-10-09
申请人： Medwaves, Inc.
发明人： ORMSBY, Theodore C. , LEUNG, George L. , SHEN, Gwo Jenn , CHU, Peter
IPC分类号： A61B18/18
CPC分类号： A61B18/1492 , A61B2017/003 , A61B2018/00839 , A61B2018/00916 , A61B2018/00946 , A61B2018/183

50. 发明公开

EP2419040A4 RADIO FREQUENCY BASED ABLATION SYSTEM AND METHOD WITH DIELECTRIC TRANSFORMER 有权
标题翻译：消融射频BASE及对应的方法有电介质变压器
公开(公告)号：EP2419040A4
公开(公告)日：2013-01-23
申请号：EP10765195
申请日：2010-04-15
申请人： MEDWAVES INC
发明人： ORMSBY THEODORE , CHUNG RUSSELL , LEUNG GEORGE , SHEN GWO JENN
IPC分类号： A61B18/18 , A61B17/3205
CPC分类号： A61B18/18 , A61B18/1815 , A61B2018/1853 , A61B2018/1869

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