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41. 发明授权

US07862574B2 Obesity treatment tools and methods 有权
标题翻译：肥胖治疗工具和方法
公开(公告)号：US07862574B2
公开(公告)日：2011-01-04
申请号：US11654783
申请日：2007-01-18
申请人： Mark E. Deem , Douglas S. Sutton , Hanson S. Gifford, III , Bernard H. Andreas , Ronald G. French
发明人： Mark E. Deem , Douglas S. Sutton , Hanson S. Gifford, III , Bernard H. Andreas , Ronald G. French
IPC分类号： A61B17/08
CPC分类号： A61B17/1114 , A61B17/00234 , A61B17/064 , A61B17/0644 , A61B17/122 , A61B2017/00557 , A61B2017/306 , A61B2090/395 , A61F5/0083 , A61F5/0086
摘要： Various obesity treatment tools and methods are described herein, as well as treatments for other gastric-related diseases, e.g., GERD. Treatment includes reducing the size of the stomach pouch to limit the caloric intake as well as to provide an earlier feeling of satiety. This may be done by creating a smaller gastric pouch within the stomach directly from the interior of the stomach itself. The smaller pouches may be made through the use of individual anchoring devices, rotating probes, or volume reduction devices. A pyloroplasty procedure may also be performed to render the pyloric sphincter incompetent. A gastric bypass procedure may additionally be performed using atraumatic magnetic anastomoses devices so that sugars and fats are passed directly to the bowel while bypassing the stomach. Many of these procedures may be done in a variety of combinations. Treatment may create enforced behavioral modifications by discouraging the ingestion of high-caloric foods.
摘要翻译：本文描述了各种肥胖治疗工具和方法，以及用于其它胃相关疾病例如GERD的治疗。治疗包括减小胃袋的尺寸以限制热量摄入以及提供较早的饱腹感。这可以通过在胃内部直接从胃内部产生较小的胃袋来完成。较小的袋可以通过使用单独的锚定装置，旋转探针或体积减小装置来制造。还可以进行幽门成形术以使幽门括约肌无能力。另外可以使用无创伤的磁性吻合装置进行胃旁路手术，使得糖和脂肪在绕过胃时直接通过肠。这些程序中的许多可以以各种组合进行。治疗可能会通过阻止摄入高热量食物而产生强制行为改变。

42. 发明申请

US20100125266A1 METHODS AND DEVICES TO TREAT COMPRESSIVE NEUROPATHY AND OTHER DISEASES 审中-公开
标题翻译：治疗压迫性神经病变和其他疾病的方法和设备
公开(公告)号：US20100125266A1
公开(公告)日：2010-05-20
申请号：US12620304
申请日：2009-11-17
申请人： Mark Deem , Vivek Shenoy , Michael Hendricksen , Hanson S. Gifford, III , Doug Sutton
发明人： Mark Deem , Vivek Shenoy , Michael Hendricksen , Hanson S. Gifford, III , Doug Sutton
IPC分类号： A61B18/02 , A61M29/00 , A61B17/32
CPC分类号： A61B18/02 , A61B17/320036 , A61B18/1492 , A61B2017/320048 , A61B2018/00214 , A61B2018/0022 , A61B2018/00982 , A61B2018/0212 , A61B2018/0225 , A61B2018/0262
摘要： Methods, systems and devices for treatment of musculoskeletal tissue may include one or more of stretching, scoring, cutting, and cryogenic cooling of the tissue. Exemplary usage includes the treatment of compressive neuropathy such as in carpal tunnel syndrome and plantar fasciitis. Other musculoskeletal tissues such as those in the hip, shoulder, and other regions of the body may also be treated.
摘要翻译：用于治疗肌肉骨骼组织的方法，系统和装置可以包括组织的拉伸，评分，切割和低温冷却中的一种或多种。示例性用途包括治疗压迫性神经病变，例如腕管综合征和足底筋膜炎。还可以处理其他肌肉骨骼组织，例如身体的臀部，肩部和其他区域中的那些。

43. 发明申请

US20100121355A1 METHODS AND DEVICES FOR SUTURE ANCHOR DELIVERY 审中-公开
标题翻译：用于固定锚固装置的方法和装置
公开(公告)号：US20100121355A1
公开(公告)日：2010-05-13
申请号：US12605065
申请日：2009-10-23
申请人： Darin C. Gittings , Mark Deem , Hanson S. Gifford, III , Doug Sutton , Vivek Shenoy
发明人： Darin C. Gittings , Mark Deem , Hanson S. Gifford, III , Doug Sutton , Vivek Shenoy
IPC分类号： A61B17/04
CPC分类号： A61B17/0642 , A61B17/0401 , A61B2017/00398 , A61B2017/00411 , A61B2017/00544 , A61B2017/00867 , A61B2017/00986 , A61B2017/0409 , A61B2017/0414 , A61B2017/0432 , A61B2017/0437
摘要： A method for impacting a suture anchor into bone comprises providing an implantable suture anchor and providing an impactor device for impacting the suture anchor into the bone. The suture anchor is coupled to a distal portion of the impactor device. Positioning the suture anchor engages the anchor with the bone at an implantation site, and powering the impactor device impacts the suture anchor thereby implanting the suture anchor into the bone. The frequency of impaction is less than 20 KHz. The impactor device is then decoupled from the suture anchor, and the impactor device may be removed from the implantation site.
摘要翻译：将缝合锚钉撞击到骨头中的方法包括提供可植入缝合锚固件并提供用于将缝合锚固件撞击到骨中的冲击器装置。缝合锚固件联接到冲击器装置的远端部分。定位缝合锚固件在植入部位处与骨头接合锚固件，并且冲击器装置的动力冲击缝合锚钉，从而将缝合锚固件植入骨骼。冲击频率小于20KHz。冲击器装置然后与缝合锚固件分离，并且冲击器装置可以从植入部位移除。

44. 发明授权

US07608091B2 Methods and apparatus for cardiac valve repair 有权
标题翻译：心脏瓣膜修复方法及装置
公开(公告)号：US07608091B2
公开(公告)日：2009-10-27
申请号：US10613443
申请日：2003-07-03
申请人： Eric A. Goldfarb , Mark E. Deem , Kent D. Dell , Martin S. Dieck , Sylvia Wen-Chin Fan , Hanson S. Gifford, III , Brain B. Martin , Ferolyn T. Powell , Frederick G. St. Goar
发明人： Eric A. Goldfarb , Mark E. Deem , Kent D. Dell , Martin S. Dieck , Sylvia Wen-Chin Fan , Hanson S. Gifford, III , Brain B. Martin , Ferolyn T. Powell , Frederick G. St. Goar
IPC分类号： A61B17/08
CPC分类号： A61B17/00234 , A61B8/10 , A61B17/04 , A61B17/0401 , A61B17/0469 , A61B17/0482 , A61B17/0487 , A61B17/0625 , A61B17/064 , A61B17/0643 , A61B17/0644 , A61B17/068 , A61B17/07207 , A61B17/08 , A61B17/122 , A61B17/1227 , A61B17/1285 , A61B17/29 , A61B18/1492 , A61B18/18 , A61B18/20 , A61B2017/00243 , A61B2017/00575 , A61B2017/00579 , A61B2017/00588 , A61B2017/00592 , A61B2017/00606 , A61B2017/00623 , A61B2017/00783 , A61B2017/00867 , A61B2017/0404 , A61B2017/0409 , A61B2017/0417 , A61B2017/0419 , A61B2017/0443 , A61B2017/045 , A61B2017/0464 , A61B2017/047 , A61B2017/0472 , A61B2017/0474 , A61B2017/0488 , A61B2017/0496 , A61B2017/06052 , A61B2017/06057 , A61B2017/06076 , A61B2017/061 , A61B2017/06171 , A61B2017/0641 , A61B2017/0649 , A61B2017/088 , A61B2017/2926 , A61B2018/00291 , A61F2/2445 , A61F2/2457
摘要： The methods, devices, and systems are provided for performing endovascular repair of atrioventricular and other cardiac valves in the heart. Regurgitation of an atrioventricular valve, particularly a mitral valve, can be repaired by modifying a tissue structure selected from the valve leaflets, the valve annulus, the valve chordae, and the papillary muscles. These structures may be modified by suturing, stapling, snaring, or shortening, using interventional tools which are introduced to a heart chamber. Preferably, the tissue structures will be temporarily modified prior to permanent modification. For example, opposed valve leaflets may be temporarily grasped and held into position prior to permanent attachment.
摘要翻译：提供的方法，装置和系统用于执行心脏中房室结和其他心脏瓣膜的血管内修复。房室瓣，特别是二尖瓣的反流可以通过修改选自瓣膜小叶，瓣膜环，瓣膜腱索和乳头肌的组织结构来修复。这些结构可以通过使用引入心脏室的介入工具通过缝合，缝合，痉挛或缩短来改变。优选地，组织结构将在永久性修饰之前临时修改。例如，相对的瓣叶可以在永久性附着之前被暂时抓住并保持就位。

45. 发明授权

US07588547B2 Methods and system for treating subcutaneous tissues 有权
标题翻译：皮下组织治疗方法及系统
公开(公告)号：US07588547B2
公开(公告)日：2009-09-15
申请号：US11334794
申请日：2006-01-17
申请人： Mark E. Deem , Hanson S. Gifford, III , Douglas Sutton
发明人： Mark E. Deem , Hanson S. Gifford, III , Douglas Sutton
IPC分类号： A61H1/00
CPC分类号： A61N7/00 , A61B2017/00747 , A61B2017/22008 , A61K9/0009 , A61K41/0028 , A61M37/0092 , A61M2037/003 , A61N1/0412 , A61N1/0492 , A61N1/327 , A61N2007/0008 , A61N2007/0039
摘要： An apparatus and method for treating subcutaneous tissues using acoustic waves in the range of low acoustic pressure ultrasound waves is disclosed. The method includes injections of enhancing agents, wherein disruption of subcutaneous tissues and subcutaneous cavitational bioeffects are produced by ultrasound waves having a power that will not produce tissue cavitation in the absence of the enhancing agents. The apparatus and method of use is useful for treatment of subcutaneous abnormalities including cellulite, lipomas, and tumors.
摘要翻译：公开了一种在低声压超声波范围内使用声波处理皮下组织的装置和方法。该方法包括注射增强剂，其中通过具有在不存在增强剂的情况下不产生组织空泡的能力的超声波产生皮下组织的破坏和皮下空泡生物效应。该装置和使用方法可用于治疗包括脂肪团，脂肪瘤和肿瘤在内的皮下异常。

46. 发明申请

US20090114226A1 METHODS AND DEVICES FOR USE IN PERFORMING PULMONARY PROCEDURES 有权
标题翻译：用于执行脉搏程序的方法和设备
公开(公告)号：US20090114226A1
公开(公告)日：2009-05-07
申请号：US12264849
申请日：2008-11-04
申请人： Mark E. Deem , Hanson S. Gifford, III , Ronald French , Douglas Sutton
发明人： Mark E. Deem , Hanson S. Gifford, III , Ronald French , Douglas Sutton
IPC分类号： A62B9/02 , A62B9/06 , A61B19/00
CPC分类号： F16K15/147 , A61B17/12022 , A61B17/12104 , A61B17/12131 , A61B17/12172 , A61B17/221 , A61B2017/1205 , A61B2017/2215 , A61B2090/061 , A61F2/04 , A61F2/24 , A61F2/2403 , A61F2/2412 , A61F2/2418 , A61F2/91 , A61F2002/043 , A61F2220/0008 , A61F2220/0016 , A61F2220/005 , Y10S128/912
摘要： Systems, methods and devices for performing pulmonary procedures, and in particular treating lung disease. A flow control element includes a valve that prevents airflow in the inhalation direction but permits airflow in the exhalation direction. The flow control element is guided to and positioned at the site by a bronchoscope that is introduced into the patient's trachea and used to view the lungs during delivery of the flow control element. The valve may include one, two or more valve elements, and it may be collapsible for easier delivery. A source of vacuum or suction may be used to increase the amount of fluid withdrawn from the lung tissue. A device for measuring hollow structures, such as bronchioles, and a device for removing a previously-placed flow control element are disclosed as well.
摘要翻译：用于执行肺部手术，特别是治疗肺部疾病的系统，方法和装置。流量控制元件包括防止气流沿吸入方向但允许呼气方向气流的阀。流量控制元件被引导到病人气管中并用于在流量控制元件的输送期间观察肺部的支气管镜引导到位置并定位在该位置处。阀可以包括一个，两个或更多个阀元件，并且其可以是可折叠的以用于更容易的输送。可以使用真空源或抽吸源来增加从肺组织排出的流体的量。还公开了一种用于测量诸如细支气管的中空结构的装置和用于去除预先安置的流量控制元件的装置。

47. 发明授权

US07306614B2 Overtube apparatus for insertion into a body 有权
标题翻译：用于插入身体的Overtube装置
公开(公告)号：US07306614B2
公开(公告)日：2007-12-11
申请号：US11364036
申请日：2006-02-28
申请人： Gary Weller , Craig Gerbi , James Gannoe , Mark E. Deem , Douglas S. Sutton , Hanson S. Gifford, III , Bernard H. Andreas , Ronald G. French
发明人： Gary Weller , Craig Gerbi , James Gannoe , Mark E. Deem , Douglas S. Sutton , Hanson S. Gifford, III , Bernard H. Andreas , Ronald G. French
IPC分类号： A61B17/08
CPC分类号： A61F5/0083 , A61B17/00234 , A61B17/0469 , A61B17/0482 , A61B17/064 , A61B17/0643 , A61B17/0644 , A61B17/068 , A61B17/072 , A61B17/07207 , A61B17/08 , A61B17/1114 , A61B17/1155 , A61B17/12013 , A61B17/122 , A61B17/29 , A61B2017/00557 , A61B2017/00818 , A61B2017/0648 , A61B2017/0649 , A61B2017/081 , A61B2017/1139 , A61B2017/12018 , A61B2017/2926 , A61B2017/306 , A61B2090/395
摘要： An overtube apparatus for insertion into a body is described herein. The assembly includes an overtube having a lumen defined throughout. The distal end of the overtube member has two or more windows in apposition configured to draw in tissue via a vacuum. A drive tube, which also defines a lumen, is inserted and is freely adjustable within the overtube. A spiral or helical fastener, which is temporarily attached to the drive tube distal end, is positioned within the overtube lumen. Endoscopic devices can be inserted within the drive tube lumen and advanced past the distal ends of both the drive tube and overtube. A pump provides the vacuum to draw apposed regions of tissue from within a hollow body organ into the windows of the overtube. Once the tissue has been invaginated, the drive tube is rotated to advance the fastener into the tissue to fasten them together.
摘要翻译：这里描述了用于插入体内的超管设备。组件包括具有整个限定的内腔的外套管。外套管构件的远端具有两个或更多个窗口，其配置构造成经由真空抽吸在组织中。还限定了管腔的驱动管被插入并且在外套管内可自由地调节。临时连接到驱动管远端的螺旋或螺旋紧固件位于外套管腔内。内窥镜装置可以插入驱动管腔内并且推进经过驱动管和外套管的远端。泵提供真空以将中空身体器官内的组织区域从外套管的窗口中抽出。一旦已经中断组织，驱动管被旋转以将紧固件推进到组织中以将它们紧固在一起。

48. 发明授权

US06932792B1 Antegrade cardioplegia catheter and method 有权
标题翻译：降血压心麻痹导管及方法
公开(公告)号：US06932792B1
公开(公告)日：2005-08-23
申请号：US09617459
申请日：2000-07-17
申请人： Frederick G. St. Goar , John H. Stevens , Hanson S. Gifford, III , Bartley P. Griffith
发明人： Frederick G. St. Goar , John H. Stevens , Hanson S. Gifford, III , Bartley P. Griffith
IPC分类号： A61F2/958 , A61M25/00 , A61M29/02 , A61M29/00
CPC分类号： A61M25/1011 , A61M25/0032 , A61M25/10 , A61M2025/0003 , A61M2025/0031 , A61M2025/0036 , A61M2025/1052 , A61M2025/1095 , A61M2025/1097 , A61M2210/125 , A61M2210/127
摘要： A cardioplegia catheter is configured to extend into the ascending aorta with a proximal portion of the shaft extending into a left chamber of the heart through a aortic valve and out of the heart through a penetration in a wall thereof. The cardioplegia catheter has an occlusion member configured to occlude the ascending aorta between the brachiocephalic artery and the coronary ostia. An arterial return cannula delivers oxygenated blood to the arterial system downstream of the occlusion member, while cardioplegic fluid is delivered through a lumen in the cardioplegia catheter upstream of the occlusion member to induce cardioplegic arrest.
摘要翻译：心麻痹导管构造成延伸到上升主动脉中，其中轴的近端部分通过主动脉瓣延伸到心脏的左室，并通过其壁中的穿透而离开心脏。心麻痹导管具有闭塞构件，其构造成阻塞头臂动脉和冠状动脉口之间的升主动脉。动脉回流套管将氧合血液输送到闭塞构件下游的动脉系统，而心脏停搏液通过闭塞构件上游的心麻痹导管内腔输送以引起心脏停搏。

49. 发明授权

US06899718B2 Devices and methods for performing avascular anastomosis 失效
标题翻译：用于进行无血管吻合的装置和方法
公开(公告)号：US06899718B2
公开(公告)日：2005-05-31
申请号：US10830897
申请日：2004-04-23
申请人： Hanson S. Gifford, III , Lee R. Bolduc , Jeffrey A. Stein , Paul C. DiCesare , Peter F. Costa , William A. Holmes
发明人： Hanson S. Gifford, III , Lee R. Bolduc , Jeffrey A. Stein , Paul C. DiCesare , Peter F. Costa , William A. Holmes
IPC分类号： A61B17/00 , A61B17/064 , A61B17/11 , A61B17/115 , A61B17/12 , A61F2/00
CPC分类号： A61B17/12109 , A61B17/064 , A61B17/0643 , A61B17/11 , A61B17/115 , A61B17/12036 , A61B17/12045 , A61B17/12136 , A61B2017/00243 , A61B2017/0641 , A61B2017/1135 , A61B2017/12127 , A61F2002/30092 , A61F2210/0014
摘要： A system for performing an end-to-side vascular anastomosis, including an anastomosis device, an application instrument and methods for performing a vascular anastomosis. The system is applicable for performing an anastomosis between a vascular graft and the ascending aorta in coronary artery bypass surgery, particularly in port-access CABG surgery. A first aspect of the invention includes a vascular anastomosis staple. A first configuration has two parts: an anchor member, forming the attachment with the target vessel wall and a coupling member, forming the attachment with the bypass graft vessel. The anastomosis is completed by inserting the coupling member, with the graft vessel attached, into the anchor member. A second configuration combines the functions of the anchor member and the coupling member into a one-piece anastomosis staple. A second aspect of the invention includes an anastomotic fitting, having an inner flange over which the graft vessel is everted and an outer flange which contacts the exterior surface of the target vessel. A tailored amount of compression applied by the inner and outer flanges grips the target vessel wall and creates a leak-proof seal between the graft vessel and the target vessel. A third aspect of the invention has a flange to which the graft vessel attaches, by everting the graft vessel over the flange, and a plurality of staple-like members which attach the flange and the everted end of the graft vessel to the wall of the target vessel to form the anastomosis
摘要翻译：一种用于执行端对侧血管吻合的系统，包括吻合装置，应用仪器和用于进行血管吻合的方法。该系统适用于在冠状动脉旁路手术中进行血管移植物和升主动脉之间的吻合，特别是在进入CABG手术中。本发明的第一方面包括血管吻合缝合物。第一构造具有两部分：锚定构件，与目标血管壁形成附件和联接构件，与旁路移植血管形成附件。通过将连接构件插入到锚定构件中来完成吻合。第二种结构将锚定构件和联接构件的功能结合成一体式吻合钉。本发明的第二方面包括一种吻合装置，其具有内部凸缘，移植物容器在其上延伸，外部凸缘接触目标血管的外表面。由内外法兰施加的定制的压缩量夹住目标血管壁，并在移植血管和靶血管之间产生防漏密封。本发明的第三方面具有凸缘，移植管通过使移植物容器穿过凸缘而附接到该凸缘上，以及多个钉状构件，其将该移植物容器的凸缘和脱出端附接到靶血管形成吻合

50. 发明授权

US06866650B2 System for cardiac procedures 失效
标题翻译：心脏手术系统
公开(公告)号：US06866650B2
公开(公告)日：2005-03-15
申请号：US09776336
申请日：2001-02-02
申请人： John H. Stevens , Wesley D. Sterman , Hanson S. Gifford, III , Timothy R. Machold
发明人： John H. Stevens , Wesley D. Sterman , Hanson S. Gifford, III , Timothy R. Machold
IPC分类号： A61B17/00 , A61F2/24 , A61F2/958 , A61M1/36 , A61M25/00 , A61M25/01 , A61M25/06 , A61M29/02 , A61M29/00
CPC分类号： A61M25/0147 , A61B2017/00243 , A61B2018/00232 , A61B2018/00261 , A61F2/2427 , A61M1/3653 , A61M1/3659 , A61M25/0032 , A61M25/0041 , A61M25/0125 , A61M25/0152 , A61M25/0662 , A61M25/10 , A61M25/1002 , A61M2025/0031 , A61M2025/0078 , A61M2025/015 , A61M2025/0161 , A61M2025/028 , A61M2025/1047 , A61M2025/1052 , A61M2025/1077 , A61M2025/1095 , A61M2202/047 , A61M2205/11 , A61M2205/366 , A61M2210/125 , A61M2210/127
摘要： A system for accessing a patient's cardiac anatomy which includes an endovascular aortic partitioning device that separates the coronary arteries and the heart from the rest of the patient's arterial system. The endovascular device for partitioning a patient's ascending aorta comprises a flexible shaft having a distal end, a proximal end, and a first inner lumen therebetween with an opening at the distal end. The shaft may have a preshaped distal portion with a curvature generally corresponding to the curvature of the patient's aortic arch. An expandable means, e.g. a balloon, is disposed near the distal end of the shaft proximal to the opening in the first inner lumen for occluding the ascending aorta so as to block substantially all blood flow therethrough for a plurality of cardiac cycles, while the patient is supported by cardiopulmonary bypass. The endovascular aortic partitioning device may be coupled to an arterial bypass cannula for delivering oxygenated blood to the patient's arterial system. The heart muscle or myocardium is paralyzed by the retrograde delivery of a cardioplegic fluid to the myocardium through patient's coronary sinus and coronary veins, or by antegrade delivery of cardioplegic fluid through a lumen in the endovascular aortic partitioning device to infuse cardioplegic fluid into the coronary arteries. The pulmonary trunk may be vented by withdrawing liquid from the trunk through an inner lumen of an elongated catheter. The cardiac accessing system is particularly suitable for removing the aortic valve and replacing the removed valve with a prosthetic valve.
摘要翻译：一种用于访问患者心脏解剖结构的系统，其包括将冠状动脉和心脏与患者动脉系统的其余部分分离的血管内主动脉分配装置。用于分隔患者升主动脉的血管内装置包括具有远端，近端和其间的第一内腔的柔性轴，在远端具有开口。轴可以具有预先形成的远端部分，其曲率通常对应于患者主动脉弓的曲率。可膨胀装置，例如靠近靠近第一内腔中的开口的轴的远端附近的气囊，用于闭塞升主动脉，以便阻止基本上所有的血液通过其进行多个心动周期，同时患者由体外循环。血管内主动脉分配装置可以联接到动脉旁路套管，用于将氧合血液输送到患者的动脉系统。通过患者的冠状窦和冠状静脉逆行递送心脏停搏液到心肌，或者通过血管内主动脉分配装置的内腔顺序递送心脏停跳液，将心肌或心肌瘫痪，将心脏停搏液注入冠状动脉。可以通过从细长的导管的内腔中抽出液体来排出肺动脉干。心脏存取系统特别适用于去除主动脉瓣并用假体瓣替换去除的瓣膜。

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