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41. 发明申请

WO2018039255A1 INFRARED CHARACTERIZATION OF A SAMPLE USING OSCILLATING MODE 审中-公开
标题翻译：采用振荡模式进行样品的红外特征分析
公开(公告)号：WO2018039255A1
公开(公告)日：2018-03-01
申请号：PCT/US2017/048049
申请日：2017-08-22
申请人： BRUKER NANO, INC. , LEHIGH UNIVERSITY
发明人： SU, Chanmin , WAGNER, Martin , XU, Xiaoji
IPC分类号： G01N21/35 , G01N21/33 , G01Q60/24 , G01N29/12
摘要： An apparatus and method of performing sample characterization with an AFM and a pulsed IR laser directed at the tip of a probe of the AFM. The laser pulses are synchronized with the oscillatory drive of the AFM and may only interact with the tip/sample on selected cycles of the oscillation. Peak force tapping mode is preferred for AFM operation. Nano-mechanical and nano-spectroscopic measurements can be made with sub-50 nm, and even sub-20 nm, resolution.
摘要翻译：利用指向AFM探针尖端的AFM和脉冲IR激光器执行样品表征的装置和方法。激光脉冲与AFM的振荡驱动同步，并且可能仅在选定的振荡周期中与尖端/样品相互作用。 AFM操作首选峰力攻丝模式。纳米机械和纳米光谱测量可以在低于50纳米，甚至低于20纳米的分辨率下进行。

42. 发明申请

WO2014193955A1 BRACKISH WATER DESALINATION USING TUNABLE ANION EXCHANGE BED 审中-公开
标题翻译：使用TINNABLE ANION交换床的包装水脱盐
公开(公告)号：WO2014193955A1
公开(公告)日：2014-12-04
申请号：PCT/US2014/039794
申请日：2014-05-28
申请人： LEHIGH UNIVERSITY
发明人： SENGUPTA, Arup K. , SMITH, Ryan C.
IPC分类号： C02F1/42
CPC分类号： C02F1/42 , B01D1/26 , C02F1/06 , C02F1/441 , C02F2001/422 , C02F2101/10 , C02F2101/101 , C02F2101/105 , C02F2101/12 , C02F2303/16 , C02F2303/22 , Y02A20/128
摘要： A process for treating feed water for desalination, the process comprising: (a) removing one or more polyvalent anions from the feed water by feeding the feed water into a bed comprising one or more anion exchange resins under conditions sufficient to exchange the polyvalent ions in the feed water with one or more monovalent anions in the resin; and (b) regenerating the bed by feeding a brine stream into the bed under conditions sufficient to exchange one or more polyvalent anions in the resins with one or more monovalent anions in the brine stream.
摘要翻译：一种用于处理用于脱盐的给水的方法，所述方法包括：（a）通过在足以交换多价离子的条件下将进料水进料到包含一种或多种阴离子交换树脂的床中，从而将来自进料水的一种或多种多价阴离子在树脂中具有一种或多种一价阴离子的给水; 和（b）通过在足以在树脂中与盐水中的一种或多种单价阴离子交换一种或多种多价阴离子的条件下将盐水流进入床中来再生床。

43. 发明申请

WO2014165666A1 THIN FILM SMALL MOLECULE ORGANIC PHOTOVOLTAIC SOLAR CELL 审中-公开
标题翻译：薄膜小分子有机光伏太阳能电池
公开(公告)号：WO2014165666A1
公开(公告)日：2014-10-09
申请号：PCT/US2014/032809
申请日：2014-04-03
申请人： LEHIGH UNIVERSITY
发明人： BARTOLI, Filbert Joseph , ZENG, Beibei
IPC分类号： H01L31/00
CPC分类号： H01L51/447 , H01L31/054 , H01L51/0037 , H01L51/0053 , H01L51/0091 , H01L51/424 , H01L51/442 , H01L51/445 , H01L2251/301 , Y02E10/549
摘要： A thin film organic photovoltaic device or solar cell in one embodiment includes an organic active bilayer and an ultrathin two-dimensional metallic nanogrid as a transparent conducting electrode which receives incident light. The nanogrid excites surface plasmonic resonances at an interface between the nanogrid and active bilayer from the incident light to enhance photon absorption in the active bilayer below the nanogrid. In another embodiment, spatially separated nanograting electrodes may alternatively be formed by double one-dimensional nanogratings disposed on opposite sides of the organic active bilayer. The spatially separated nanogratings may be oriented perpendicular to each other.
摘要翻译：在一个实施方案中，薄膜有机光伏器件或太阳能电池包括有机活性双层和作为透明导电电极的超薄二维金属纳米网格，其接收入射光。纳米格栅从入射光在纳米网格和活性双层之间的界面处激发表面等离子体共振，以增强在纳米网格下方的活性双层中的光子吸收。在另一个实施方案中，空间分离的纳米晶化电极可以替代地通过设置在有机活性双层的相对侧上的双一维纳米晶格形成。空间分离的纳米玻璃可以彼此垂直取向。

44. 发明申请

WO2014144073A3 AUGMENTING MOIETIES FOR ANTI-INFLAMMATORY COMPOUNDS 审中-公开
公开(公告)号：WO2014144073A3
公开(公告)日：2014-09-18
申请号：PCT/US2014/028329
申请日：2014-03-14
申请人： RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY , LEHIGH UNIVERSITY
发明人： LASKIN, Jeffrey, D. , HECK, Diane, E. , LACEY, Carl, Jeffrey , HEINDEL, Ned, D. , YOUNG, Sherri, C.
IPC分类号： A61P29/00 , A61K31/27
摘要： Augmented or synergized anti-inflammatory constructs are disclosed including terpenes covalently conjugated with other anti-inflammatory molecules such as nonsteroidal anti-inflammatory drugs, vanilloids, amino acids and polyamines; and anti-inflammatory molecules covalently conjugated with specific amino acids. For the latter, further conjugation with a choline bioisostere further augments the anti-inflammatory activity.

45. 发明申请

WO2014089504A1 SYSTEM AND METHOD FOR PARALLEL IMAGING OPTICAL COHERENCE TOMOGRAPHY 审中-公开
标题翻译：用于平行成像光学相干坐标系统和方法
公开(公告)号：WO2014089504A1
公开(公告)日：2014-06-12
申请号：PCT/US2013/073704
申请日：2013-12-06
申请人： LEHIGH UNIVERSITY
发明人： ZHOU, Chao
IPC分类号： G01B9/02
CPC分类号： G01B9/02012 , G01B9/02027 , G01B9/02091 , G01N21/4795
摘要： A parallel imaging optical coherence tomography system. In one embodiment, the system includes a light source, a movable scan unit, and an interferometer comprising a reference arm and a sample arm. The scan unit includes a plurality of apertures illuminated by incident light from the light source. The scan unit produces a plurality of light beams transmitted to the interferometer. The light beams are each split producing a plurality of reference and sampling beams. The sampling beams are scanned onto a sample and return reflected sampling light signals through the sample arm which are combined with reflected, reference light signals from the reference arm An interference pattern is formed which Is detected by an image sensor and processed to generate a digital image of the sample. In some embodiments, the scan unit may include a microlens array, A related scanning method is also provided.
摘要翻译：平行成像光学相干断层扫描系统。在一个实施例中，系统包括光源，可移动扫描单元和包括参考臂和样本臂的干涉仪。扫描单元包括由来自光源的入射光照射的多个孔。扫描单元产生传输到干涉仪的多个光束。光束每个分割产生多个参考和采样光束。采样光束被扫描到样品上，并通过样品臂返回反射的采样光信号，该信号与来自参考臂的反射的参考光信号组合。形成由图像传感器检测并被处理以产生数字图像的干涉图案的样品。在一些实施例中，扫描单元可以包括微透镜阵列，还提供了相关的扫描方法。

46. 发明申请

WO2014059313A1 THERMALLY STABLE ENZYMES, COMPOSITIONS THEREOF AND METHODS OF USING SAME 审中-公开
标题翻译：热稳定酶，其组合物及其使用方法
公开(公告)号：WO2014059313A1
公开(公告)日：2014-04-17
申请号：PCT/US2013/064604
申请日：2013-10-11
申请人： LEHIGH UNIVERSITY
发明人： BERGER, Bryan, William
IPC分类号： C12R1/01
CPC分类号： C12N9/88 , A01N63/00 , A01N63/02 , A01N65/03 , A61K38/00 , A61K38/51 , C11D3/38636 , C12P7/04 , C12P7/06 , C12P7/16 , C12P7/649 , C12P19/02 , C12Y402/02 , C12Y402/02001 , C12Y402/02003 , C12Y402/02014 , Y02P20/52
摘要： Described herein are proteins having lyase activity and nucleic acid sequences which code therefore; along with methods of expressing, isolating, purifying, and using same. The present invention provides methods of preventing, treating or inhibiting a disease, disorder or condition selected from: a urinary tract infection, a catheter-originated infection, a middle-ear infection, dental plaque, gingivitis, an eye infection, endocarditis, cystic fibrosis, and nosocomial infections, comprising administering an effective amount of a composition.
摘要翻译：本文描述了具有裂解酶活性的蛋白质和因此编码的核酸序列; 以及表达，分离，纯化和使用相同的方法。本发明提供预防，治疗或抑制选自以下的疾病，病症或病症的方法：尿路感染，导管起源感染，中耳感染，牙菌斑，牙龈炎，眼睛感染，心内膜炎，囊性纤维化和医院感染，包括施用有效量的组合物。

47. 发明申请

WO2012145407A2 SUPERCAPACITIVE SWING ADSORPTION 审中-公开
标题翻译：超吸收式吸收
公开(公告)号：WO2012145407A2
公开(公告)日：2012-10-26
申请号：PCT/US2012/034096
申请日：2012-04-18
申请人： LEHIGH UNIVERSITY , LANDSKRON, Kai , MOORE, David, T. , FINAMORE, Nina , KOKOSZKA, Berenika , LIU, Cong , MOHANTY, Paritosh
发明人： LANDSKRON, Kai , MOORE, David, T. , FINAMORE, Nina , KOKOSZKA, Berenika , LIU, Cong , MOHANTY, Paritosh
IPC分类号： B01D53/32 , B01D53/02 , B01D53/047 , B01D53/86 , B01D53/62
CPC分类号： B01D53/326 , B01D53/04 , B01D53/323 , B01D2257/504 , Y02C10/08
摘要： Desirable gas separation technologies, including novel methods and systems, are provided herein. The inventive gas separation technologies presented herein utilize supercapacitive swing adsorption ("SSA") top selectively remove at least one chemical from a gas stream, such as the waste gas exhaust stream of a coal-fired electrical power generation plant. In some embodiments, the supercapacitive apparatus comprises a novel prepared mesoporous material comprising tungsten, preferably as WO3.
摘要翻译：本文提供了理想的气体分离技术，包括新颖的方法和系统。本文提出的本发明的气体分离技术利用超级容量变换吸附（“SSA”）顶部选择性地从燃气流中除去至少一种化学物质，例如燃煤发电厂的废气排放流。在一些实施例中，超电容装置包括新型制备的介孔材料，其包含钨，优选为WO 3。

48. 发明申请

WO2011116112A3 FABRICATION OF POROUS GLASS BIOSCAFFOLDS BY SOL-GEL AND POLYMER SPONGE METHODS 审中-公开
公开(公告)号：WO2011116112A3
公开(公告)日：2011-09-22
申请号：PCT/US2011/028695
申请日：2011-03-16
申请人： LEHIGH UNIVERSITY , JAIN, Himanshu , WANG, Shaojie
发明人： JAIN, Himanshu , WANG, Shaojie
IPC分类号： A61L27/56 , A61L27/10 , C03B19/00 , C01B33/16 , A61F2/02
摘要： Provided herein are biocompatible scaffolds and methods of preparing such bioscaffolds. The methods provide a superior high surface area, interconnected nanomacroporous bioactive glass scaffold, by combining a sol-gel process and polymer sponge replication methods. The formation of a uniformly nanoporous and interconnected macroporous bioscaffold is demonstrated using a starting material comprising a 70 mol% SiO2-30 mol% CaO glass composition as an example. The bioscaffold includes a series of open, interconnected macropores with size from 300 to 600 µm, as desired for tissue ingrowth and vascularization. At the same time, coexisting nanopores provide high-specific surface area (>150 m2/g), which is needed for enhancing the structure's degradation rate. These bioscaffolds hold promise for applications in hard tissue engineering.

49. 发明申请

WO2009082404A1 STAGGERED COMPOSITION QUANTUM WELL METHOD AND DEVICE 审中-公开
公开(公告)号：WO2009082404A1
公开(公告)日：2009-07-02
申请号：PCT/US2007/088778
申请日：2007-12-24
申请人： LEHIGH UNIVERSITY , TANSU, Nelson , ARIF, Ronald, A. , Ee, Yik, Khoon , ZHAO, Hongping
发明人： TANSU, Nelson , ARIF, Ronald, A. , Ee, Yik, Khoon , ZHAO, Hongping
IPC分类号： H01L33/00
CPC分类号： H01L33/06 , B82Y20/00 , H01L33/32 , H01S5/0014 , H01S5/342 , H01S5/3422 , H01S5/34333
摘要： A light emitting device comprising a staggered composition quantum well.
摘要翻译：一种包括交错组合量子阱的发光器件。

50. 发明申请

WO2008101011A1 NANO/MACROPOROUS BIOACTIVE GLASSES MADE BY MELT-QUENCH METHODS 审中-公开
标题翻译： NANO /通过熔融法制造的大面积生物玻璃
公开(公告)号：WO2008101011A1
公开(公告)日：2008-08-21
申请号：PCT/US2008/053851
申请日：2008-02-13
申请人： LEHIGH UNIVERSITY , JAIN, Himanshu , MOAWAD, Hassan, Mohamady, Mohamed
发明人： JAIN, Himanshu , MOAWAD, Hassan, Mohamady, Mohamed
IPC分类号： B82B3/00
CPC分类号： A61L27/10 , A61L27/56
摘要： The methods and materials described herein provide novel and simple procedures for the preparation of nano/macroporous glasses, in which the pore structure is characterized by interconnected pores of, e.g., both hundreds of micrometers and several to tens of nanometers in size. Such materials may be used for enhanced bone regeneration, bioscaffolds, drug delivery devices, and filtration media, among other uses. For example, silica-based bone tissue scaffolds are made with a controlled nano/macroporosity, which enhances bone regeneration performance. Also provided herein are new biocompatible CaO-Na 2 O-P 2 O 5 -S i O 2 glasses prepared by thermal melt-quench methods that result in spinodal phase separation and crystallization of phases at very different length scales. Selective chemical leaching of these phases causes formation of interconnected multi-modal porosity, with pore sizes ranging from several nanometers to tens of micrometers.
摘要翻译：本文所述的方法和材料提供了用于制备纳米/大孔玻璃的新颖且简单的方法，其中孔结构的特征在于尺寸为几百微米和数十纳米的互连孔。除了其它用途之外，这种材料可用于增强骨再生，生物支架，药物递送装置和过滤介质。例如，二氧化硅基骨组织支架用受控的纳米/大孔隙度制成，这增强了骨再生性能。本文还提供了新的生物相容性CaO-Na 2 O 2 O 2 O 2 -Si O 2 通过热熔融淬火方法制备的玻璃杯，其导致相分离并在非常不同的长度尺度下结晶相。这些相的选择性化学浸出导致互连的多模式孔隙的形成，其孔径范围从几纳米到几十微米。

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