专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

31. 发明授权

EP1333848B1 PHYLLANTHUS-DERIVED COMPOUNDS FOR THE PREVENTION AND/OR TREATMENT OF DISEASES ASSOCIATED WITH A RETROVIRUS 有权
标题翻译：化合物余甘与逆转录病毒相关的预防和/或治疗疾病的
公开(公告)号：EP1333848B1
公开(公告)日：2006-04-05
申请号：EP01986262.2
申请日：2001-10-05
申请人： Phytrix AG
发明人： WAGNER, Ralf , NOTKA, Frank
IPC分类号： A61K36/47 , A61K127/00 , A61K31/70 , A61P31/14
CPC分类号： A61K36/47
摘要： The present invention relates to the use a Phyllanthus extract or a fraction thereof or a gallotannin or a combination of gallontannins for the preparation of a pharmaceutical composition for the prevention or treatment of retrovirus related diseases associated with a nucleosidic inhibitor-resistant retrovirus and/or a non-nucleosidic inhibitor-resistant retrovirus. Preferably, the retrovirus is a human immunodeficiency virus (HIV). In accordance with the present invention, it is further preferred that said gallotannin or combination of gallotannins is or comprises corilagin and/or geraniin and another ellagitannin. Further preferred is that said Phyllanthus is Phyllanthus amarus.

32. 发明专利

AT392901T 未知
公开(公告)号：AT392901T
公开(公告)日：2008-05-15
申请号：AT03809721
申请日：2003-10-02
申请人： PHYTRIX AG
发明人： VAN DER GIESSEN ROBERT H M , OLANOW WAREN , LEES ANDREW , WAGNER HILDEBERT
IPC分类号： A61K36/48 , A61P25/16 , A61P25/28
摘要： The present invention provides pharmaceutical compositions comprising Mucuna pruriens seeds or one or more Mucuna pruriens seed components, substances, fractions or mixtures or substances obtained therefrom. Furthermore, the invention relates to the use of Mucuna pruriens seed powder or one or more Mucuna pruriens components, substances, fractions or mixtures or substances obtained therefrom for the preparation of a pharmaceutical composition for preventing, alleviating or treating neurological diseases. Additionally, the invention relates to the use of Mucuna pruriens seeds for the preparation of a pharmaceutical composition for neuroprotection or neurostimulation and to methods of preparing extracts of Mucuna pruriens which can be used for the preparation of a pharmaceutical composition for treating neurological diseases. Finally, the invention relates to the use of Mucuna pruriens seeds for the preparation of a pharmaceutical composition for the treatment of Parkinson's Disease to obtain a broader therapeutic window in L-Dopa therapy, to delay a need for combination therapy, to obtain an earlier onset and longer duration of L-Dopa efficacy, and to prevent or alleviate acute and chronic L-Dopa toxicity.

33. 发明专利

ES2227298T3 PROCEDIMIENTO PARA LA PRODUCCION DE EXTRACTOS DE PHYLLANTHUS. 未知
公开(公告)号：ES2227298T3
公开(公告)日：2005-04-01
申请号：ES01982401
申请日：2001-10-05
申请人： PHYTRIX AG
发明人： KREUTER MATTHIAS-HEINRICH , WAGNER HILDEBERT K M , TITTEL GEROLF
IPC分类号： A23L1/30 , A61K9/20 , A61K9/28 , A61K9/48 , A61K36/47 , A61K47/30 , A61K47/36 , B01D11/02 , B01D61/14 , A61K35/78
摘要： Procedimiento para la producción de un extracto de Phyllanthus, en el que (a) se extraen componentes de Phyllanthus con una mezcla de etanol / agua del 5-85% m/m, a la que se ha añadido un agente quelante de metales pesados en una concentración del 0, 001-3% m/m; (b) al extracto primario obtenido en el paso (a) se le añaden (ba)goma karaya india en una concentración final del 0, 5- 5, 0% m/m, referido a la suma de las materias extractivas, o (bb)uno o varios polímeros, así como (una) sustancia(s) poco soluble(s) y/o soluble(s), y el extracto se concentra; y (c) el extracto concentrado obtenido en el paso (b) se seca.

34. 发明专利

DK1176971T3 未知
公开(公告)号：DK1176971T3
公开(公告)日：2005-02-28
申请号：DK00927102
申请日：2000-04-28
申请人： PHYTRIX AG
发明人： WAGNER HILDEBERT , VOLLMAR ANGELIKA , MANNS MICHAEL , GEBHARDT ROLF , BAHR MATTHIAS , BUNIATIAN GAYANE HRACHIA
IPC分类号： A61P1/16 , A61K35/78

35. 发明专利

PT1326624E 未知
公开(公告)号：PT1326624E
公开(公告)日：2005-01-31
申请号：PT01982401
申请日：2001-10-05
申请人： PHYTRIX AG
发明人： KREUTER MATTHIAS-HEINRICH , WAGNER HILDEBERT K M , GEROLF TITTEL
IPC分类号： A23L1/30 , A61K9/20 , A61K9/28 , A61K9/48 , A61K36/47 , A61K47/30 , A61K47/36 , B01D11/02 , B01D61/14 , A61K35/78

36. 发明专利

PT1176971E 未知
公开(公告)号：PT1176971E
公开(公告)日：2005-01-31
申请号：PT00927102
申请日：2000-04-28
申请人： PHYTRIX AG
发明人： HILDEBERT WAGNER , ANGELIKA VOLLMAR , MICHAEL MANNS , ROLF GEBHARDT , MATTHIAS BAHR , HRACHIA BUNIATIAN GAYANE
IPC分类号： A23L1/30 , A61K9/06 , A61K9/08 , A61K9/107 , A61K9/14 , A61K9/20 , A61K31/355 , A61K31/375 , A61K36/00 , A61K36/47 , A61K45/00 , A61P1/04 , A61P1/16 , A61P1/18 , A61P9/10 , A61P11/00 , A61P13/00 , A61P13/12 , A61P19/02 , A61P29/00 , A61P31/20 , A61P35/00 , A61P37/02 , A61P43/00 , C12N9/99 , A61K35/78
摘要： The present invention relates to the use of Phyllanthus for preventing or treating connective tissue proliferations, for maintaining the level of reduced glutathione, for inhibiting lipopolysaccharide (LPS)-induced nitric oxide synthase (NOS) and for inhibiting expression of the cyclooxygenase (COX-2) protein.

37. 发明专利

AT275411T 未知
公开(公告)号：AT275411T
公开(公告)日：2004-09-15
申请号：AT00927102
申请日：2000-04-28
申请人： PHYTRIX AG
发明人： WAGNER HILDEBERT , VOLLMAR ANGELIKA , MANNS MICHAEL , GEBHARDT ROLF , BAHR MATTHIAS , BUNIATIAN GAYANE HRACHIA
IPC分类号： A23L1/30 , A61K9/06 , A61K9/08 , A61K9/107 , A61K9/14 , A61K9/20 , A61K31/355 , A61K31/375 , A61K36/00 , A61K36/47 , A61K45/00 , A61P1/04 , A61P1/16 , A61P1/18 , A61P9/10 , A61P11/00 , A61P13/00 , A61P13/12 , A61P19/02 , A61P29/00 , A61P31/20 , A61P35/00 , A61P37/02 , A61P43/00 , C12N9/99 , A61K35/78
摘要： The present invention relates to the use of Phyllanthus for preventing or treating connective tissue proliferations, for maintaining the level of reduced glutathione, for inhibiting lipopolysaccharide (LPS)-induced nitric oxide synthase (NOS) and for inhibiting expression of the cyclooxygenase (COX-2) protein.

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式