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31. 发明授权

US07595082B2 Wire guide 有权
标题翻译：导线导轨
公开(公告)号：US07595082B2
公开(公告)日：2009-09-29
申请号：US10813423
申请日：2004-03-30
申请人： John J. Connors, III , Kurt J. Tekulve , Thomas A. Osborne
发明人： John J. Connors, III , Kurt J. Tekulve , Thomas A. Osborne
IPC分类号： B05D3/12 , A61M25/09 , A61M31/00
CPC分类号： A61M25/09 , A61M25/01 , A61M2025/09133 , A61M2025/09175
摘要： A wire guide includes a mandrel that has a proximal portion and a distal portion. A first coating with a low coefficient of friction is disposed on the proximal portion of the mandrel. A second coating is disposed on the distal portion of the mandrel, where the second coating provides a sub-structure. A third coating is disposed on the second coating, where the third coating comprises a surface that allows for easy maneuverability of the wire guide. The first coating on the proximal portion provides enough lubricity to keep the wire guide from becoming bound or stuck in a catheter or medical device while still allowing a user to have a good grip of the wire guide. The second coating on the distal portion provides lubricity for the wire guide, which allows the user to easily maneuver the wire guide through a vascular anatomy.
摘要翻译：线引导件包括具有近端部分和远端部分的心轴。具有低摩擦系数的第一涂层设置在心轴的近端部分上。第二涂层设置在心轴的远端部分上，其中第二涂层提供子结构。第三涂层设置在第二涂层上，其中第三涂层包括允许导线器易于操作的表面。近端部分上的第一涂层提供足够的润滑性以保持线引导件不会被粘合或卡在导管或医疗装置中，同时仍然允许使用者具有良好的电线导向器的抓地力。远端部分上的第二涂层为线引导件提供润滑性，其允许使用者容易地通过血管解剖结构操纵线引导件。

32. 发明申请

US20090171441A1 ENDOVASCULAR GRAFT WITH SEPARATELY POSITIONABLE AND REMOVABLE FRAME UNITS 有权
标题翻译：具有独立定位和可移除的框架单元的内部叶片
公开(公告)号：US20090171441A1
公开(公告)日：2009-07-02
申请号：US12339596
申请日：2008-12-19
申请人： Thomas A. Osborne
发明人： Thomas A. Osborne
IPC分类号： A61F2/06
CPC分类号： A61F2/013 , A61F2/07 , A61F2/89 , A61F2002/016 , A61F2002/065 , A61F2002/9534 , A61F2220/0058 , A61F2230/005 , A61F2230/0054 , A61F2230/008 , A61F2230/0093
摘要： A device for repairing a vessel body including a plurality distinct and independently positionable, expandable frame units disposed within a tubular graft. The independent frame units are capable of being positioned, repositioned, or removed to conform the tubular graft to the anatomy of the vessel body.
摘要翻译：一种用于修理容器主体的装置，包括设置在管状移植物内的多个不同且可独立定位的可扩展框架单元。独立的框架单元能够定位，重新定位或移除以使管状移植物符合血管体的解剖结构。

33. 发明授权

US07550004B2 Endoluminal device with extracellular matrix material and methods 有权
标题翻译：腔内装置与细胞外基质材料及方法
公开(公告)号：US07550004B2
公开(公告)日：2009-06-23
申请号：US11094021
申请日：2005-03-30
申请人： Clinton D. Bahler , Michael P. DeBruyne , Neal E. Fearnot , Alan R. Leewood , Jason A. Mead , Thomas A. Osborne , Jichao Sun , Lal Ninan
发明人： Clinton D. Bahler , Michael P. DeBruyne , Neal E. Fearnot , Alan R. Leewood , Jason A. Mead , Thomas A. Osborne , Jichao Sun , Lal Ninan
IPC分类号： A61F2/06
CPC分类号： A61F2/07 , A61F2/0077 , A61F2/848 , A61F2/89 , A61F2/915 , A61F2002/061 , A61F2002/065 , A61F2002/075 , A61F2002/8483 , A61F2002/8486 , A61F2230/005 , A61F2230/0054 , A61F2230/0067 , A61F2250/0065
摘要： An endoluminal device comprises a stent and a tubular graft supported by the stent. The graft has a proximal and a distal opening and comprises a synthetic material and a bioremodelable material. The bioremodelable material is disposed on an exterior surface in at least one band adjacent at least one of the proximal and distal openings.
摘要翻译：腔内装置包括支架和由支架支撑的管状移植物。移植物具有近端和远端开口，并且包括合成材料和生物可重构材料。生物可重塑材料设置在邻近近端和远端开口中的至少一个的至少一个带中的外表面上。

34. 发明申请

US20090157014A1 Device for enabling repeated access to a vessel 有权
标题翻译：允许重复访问船只的装置
公开(公告)号：US20090157014A1
公开(公告)日：2009-06-18
申请号：US12316734
申请日：2008-12-16
申请人： Thomas A. Osborne , Michael H. Palne
发明人： Thomas A. Osborne , Michael H. Palne
IPC分类号： A61M25/00 , A61M31/00
CPC分类号： A61M39/0208 , A61M1/3661 , A61M39/04 , A61M2039/0238
摘要： An implantable prosthesis with at least one fenestration in a side wall of that prosthesis is disclosed. The fenestration provides an access port through which a medical device (such as a needle or a cannula) can be directed to enable access to the lumen of the blood vessel which the prosthesis is supporting.
摘要翻译：公开了一种在该假体的侧壁中具有至少一个开窗的可植入假体。开窗提供了一个入口，通过该入口可以引导医疗装置（例如针或套管），以使得能够进入假体正在支撑的血管的内腔。

35. 发明授权

US07445611B2 Hemostasis cannula 有权
标题翻译：止血套管
公开(公告)号：US07445611B2
公开(公告)日：2008-11-04
申请号：US10737313
申请日：2003-12-16
申请人： Thomas A. Osborne , Ram H. Paul
发明人： Thomas A. Osborne , Ram H. Paul
IPC分类号： A61M39/06 , A61M5/36
CPC分类号： A61M39/0606 , A61M2039/062 , A61M2039/0633 , A61M2039/064 , A61M2039/0653
摘要： A medical instrument includes a housing having a housing member with a passage through which a catheter is inserted. A valve body is mounted in the housing and abuts the housing member at an end of the passage, and, as the catheter penetrates through the valve body, the valve body conforms to the outer wall of the catheter to maintain a fluid tight seal between the valve body and the catheter. When the valve body is unstressed before being mounted in the passage, the valve body has a first planar dimension and a second planar dimension that is less than the first planar dimension.
摘要翻译：医疗器械包括具有壳体构件的壳体，该壳体具有插入导管的通道。阀体安装在壳体中并且在通道的端部处邻接壳体构件，并且当导管穿过阀体时，阀体与导管的外壁相一致，以保持流体密封阀体和导管。当阀体在安装在通道中之前不受应力时，阀体具有第一平面尺寸和小于第一平面尺寸的第二平面尺寸。

36. 发明授权

US07081132B2 Flexible barb for anchoring a prosthesis 有权
公开(公告)号：US07081132B2
公开(公告)日：2006-07-25
申请号：US10431809
申请日：2003-05-08
申请人： William A. Cook , Michael P. DeBruyne , Benjamin Nickless , Thomas A. Osborne
发明人： William A. Cook , Michael P. DeBruyne , Benjamin Nickless , Thomas A. Osborne
IPC分类号： A61F2/06
CPC分类号： A61F2/82 , A61F2002/8483
摘要： A barbed medical prosthesis is disclosed in which the barb includes a basal portion comprising a point of union with the substrate of origin (such as a strut), an anchoring portion adapted to embed into tissue, and a stress-dispersing portion located between the basal and anchoring portions. In one embodiment the stress-dispersing portion comprises a helical coil having a free winding that is unattached to the strut from which the barb extends. In another embodiment, the stress-dispersing portion comprises a series of bends or curves formed in the barb proximate to the point of union with the strut. The barb can be mechanically attached and/or soldered to the prosthesis, or integrally formed therefrom. A second barb portion and stress-dispersing portion, may also extend from the basal portion.

37. 发明授权

US06939337B2 Medical device including tube having a braid and an expanded coil 有权
标题翻译：医疗装置包括具有编织物和扩张线圈的管
公开(公告)号：US06939337B2
公开(公告)日：2005-09-06
申请号：US09905017
申请日：2001-07-13
申请人： Fred T. Parker , Thomas A. Osborne
发明人： Fred T. Parker , Thomas A. Osborne
IPC分类号： A61B1/00 , A61F2/958 , A61L29/00 , A61L29/02 , A61L29/04 , A61L29/12 , A61M25/00 , A61M25/16 , F16L11/08
CPC分类号： A61L29/126 , A61L29/02 , A61L29/04 , A61M25/0053 , A61M25/0054 , A61M2025/0079
摘要： A medical device (10) including a tube (11) having a highly uniform and repeatable inner and outer diameter, the tube (11) possessing good trackability, pushability and torquability, and the tube (11) being highly resistant to collapse, necking or kinking during use. The tube (11) first includes a metal coil (14) in a stressed, radially expanded condition, the metal coil (14) preferably being formed as a flat wire. The tube (11) also includes a metal braid (16) extending over at least part of the coil (14). The tube (11) further includes a polymeric bonding layer (18) positioned over and contacting at least the coil (14). The polymeric layer (18) is preferably heat-shrinkable shrinkable tubing made of one or more of nylon or polyurethane. The tube (11) optionally includes an inner liner (20) beneath and in contact with at least part of the coil (14), the liner (20) preferably being composed of PTFE. The polymeric layer (18) maintains the coil (14) in its stressed, radially expanded condition, for example, by adhesion to the coil (14) (such as by thermal bonding to it).
摘要翻译：一种医疗装置（10），其包括具有高度均匀且可重复的内径和外径的管（11），所述管（11）具有良好的跟踪性，推挤性和扭矩，并且管（11）具有高度抗崩溃，颈缩或使用中扭结。管（11）首先包括处于应力的径向膨胀状态的金属线圈（14），金属线圈（14）优选地形成为扁线。管（11）还包括在线圈（14）的至少一部分上延伸的金属编织物（16）。管（11）还包括位于至少线圈（14）上并与其接触的聚合物粘合层（18）。聚合物层（18）优选是由尼龙或聚氨酯中的一种或多种制成的热收缩性可收缩管。管（11）任选地包括在线圈（14）的至少一部分下方并与其接触的内衬（20），衬垫（20）优选地由PTFE构成。聚合物层（18）例如通过与线圈（14）的粘附（例如通过热粘合）将线圈14维持在其受应力的径向膨胀状态。

38. 发明授权

US06544269B2 Localizer needle 有权
公开(公告)号：US06544269B2
公开(公告)日：2003-04-08
申请号：US09897246
申请日：2001-07-02
申请人： Thomas A. Osborne , Kurt J. Tekulve
发明人： Thomas A. Osborne , Kurt J. Tekulve
IPC分类号： A61B1734
CPC分类号： A61B90/39 , A61B2017/00349 , A61B2090/3908
摘要： A medical device (10) includes at least a stylet (12) for establishing the location of tissue of interest, such as a nonpalpable lesion in breast tissue. The device may also include a needle assembly (14) and an aspiration syringe (16). The medical device (10) can most readily be understood as an improvement in Kopans-type or hookwire-type localizer stylet having a wire shaft (18) with a distal end (28), and a hook (36) depending in a proximal direction from the wire shaft (18). The improvements entail spacing the hook (36) proximally of the distal end (28) of the wire shaft (18), and providing the wire shaft with a twist between the hook (36) and the distal end (28) of the wire shaft (18). Wire shaft (18) has first and second wire segments (20 and 30), each including a respective distal twisted portion (24 or 34) adjacent its respective distal end (22 or 32). The first wire segment (20) further includes a generally straight portion (26) extending proximally of its distal twisted portion (24), while the second wire segment (30) further includes a hook (36) extending proximally of its distal twisted portion (34).

39. 发明授权

US06464720B2 Radially expandable stent 有权
标题翻译：径向扩张支架
公开(公告)号：US06464720B2
公开(公告)日：2002-10-15
申请号：US09822066
申请日：2001-03-30
申请人： Scott E. Boatman , Kimberly D. Brummett , Thomas A. Osborne
发明人： Scott E. Boatman , Kimberly D. Brummett , Thomas A. Osborne
IPC分类号： A61F206
CPC分类号： A61F2/915 , A61F2/88 , A61F2/91 , A61F2002/91508 , A61F2002/91516 , A61F2002/91525 , A61F2002/91533 , A61F2002/91558 , A61F2002/91566 , A61F2002/91575 , A61F2002/91583 , A61F2230/0054 , A61F2250/0036 , A61F2250/0098 , A61L31/022 , A61L31/18
摘要： A radially expandable stent (10) made from a cannula or sheet of biocompatible material that includes at least one longitudinal segment (14) comprised of a series of laterally interconnected closed cells (13). Each closed cell of a longitudinal segment is defined laterally by a pair of longitudinal struts (15, 16) that are interconnected at each end by a circumferentially adjustable member (19, 20). When the stent is expanded using a balloon (47), the opposing circumferentially adjustable members deform to allow circumferential expansion of the longitudinal segment, while the length of the segment, as defined by the longitudinal struts, is maintained. Self-expanding versions of the stent utilize a nickel-titanium alloy. Adjacent longitudinal segments are joined by flexible interconnection segments (21) that permit the stent to bend laterally. The flexible interconnection segment is comprised of curvilinear struts (22, 23) that form a series of serpentine bends (81) that distribute lateral bending forces. In a preferred embodiment, a short strut interconnects longitudinal segments and an adjacent interconnection segment. Each interconnection strut attaches to the longitudinal segment within a region (27) at the end (17) of a longitudinal strut (15) dividing two adjacent closed cells.
摘要翻译：一种由包括生物相容性材料的套管或片材制成的径向可扩张的支架（10），其包括由一系列横向互连的闭孔（13）构成的至少一个纵向段（14）。纵向段的每个闭合单元由一对纵向支柱（15,16）侧向地限定，所述纵向支柱在每个端部由周向可调节构件（19,20）互连。当使用球囊（47）扩张支架时，相对的周向可调部件变形以允许纵向段的周向膨胀，而由纵向支柱限定的段的长度保持。自扩张型支架采用镍钛合金。相邻的纵向段通过柔性互连段（21）连接，允许支架横向弯曲。柔性互连部分由曲线支柱（22,23）组成，其形成分布横向弯曲力的一系列蛇形弯曲部（81）。在优选实施例中，短支柱将纵向段和相邻互连段互连。每个互连支柱在分开两个相邻闭孔的纵向支柱（15）的端部（17）处的区域（27）内附接到纵向段。

40. 发明授权

US5251640A Composite wire guide shaft 失效
标题翻译：复合导丝轴
公开(公告)号：US5251640A
公开(公告)日：1993-10-12
申请号：US861428
申请日：1992-03-31
申请人： Thomas A. Osborne
发明人： Thomas A. Osborne
IPC分类号： A61M25/00 , A61B5/00
CPC分类号： A61L31/121 , A61M25/09 , A61M2025/0915 , A61M2025/09191
摘要： A composite wire guide shaft includes first and second sets of fibers which are arranged along a longitudinal axis and are embedded in an epoxy matrix. The first set of fibers are arranged substantially parallel to the longitudinal axis of the wire guide shaft and the remaining second set of fibers are helically wound in opposing directions about the longitudinal axis. The longitudinally parallel fibers provide pushability to the wire guide shaft while the helically wound fibers provide rotational stiffness for improved torqueability.
摘要翻译：复合线引导轴包括沿着纵向轴线布置并嵌入在环氧基体中的第一和第二组纤维。第一组纤维被布置成基本上平行于线引导轴的纵向轴线，并且剩余的第二组纤维围绕纵向轴线以相反方向螺旋缠绕。纵向平行的纤维提供对线引导轴的推力，而螺旋卷绕的纤维提供旋转刚度以提高扭矩。

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