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    • 39. 发明申请
    • MICROBIOCIDAL HETEROCYCLES
    • 微生物杂交
    • WO2013000943A1
    • 2013-01-03
    • PCT/EP2012/062428
    • 2012-06-27
    • SYNGENTA PARTICIPATIONS AGSULZER-MOSSE, SarahLAMBERTH, ClemensCEDERBAUM, Fredrik Emil Malcolm
    • SULZER-MOSSE, SarahLAMBERTH, ClemensCEDERBAUM, Fredrik Emil Malcolm
    • C07D401/06C07D401/12C07D401/14C07D403/06C07D403/12C07D403/14A01N43/56A01N43/54
    • A01N43/60A01N43/56C07D401/06C07D401/12C07D401/14C07D403/06C07D403/12C07D403/14
    • The present invention relates to heterocyclic compounds of formula I which have microbiocidal activity, in particular fungicidal activity as well as methods of using the compounds of formula (I) to control microbes: wherein A is x-C(R 10 R 11 )-C(=O)-, x-C(R 12 R 13 )-C(=S)-, x-O-C(=O)-, x-O-C(=S)-, x-N(R 14 )-C(=O)-, x-N(R 15 )-C(=S)-, x-C(R 16 R 17 )-SO 2 - or x-N=C(R 30 )-,, in each case x indicates the bond that is connected to R 1 ; T is CR 18 or N; Y 1 , Y 2 , Y 3 , and Y 4 are independently CR 19 or N; Q is O or S; n is 1 or 2; p is 1 or 2, providing that when n is 2, p is 1. R 1 is (formula A) R 2 , R 3 , R 4 , R 5 , R 6 , R 7 , R 10 , R 11 , R 12 , R 13 , R 16 , R 17 , R 18 ,R 19 and R 30 each independently are hydrogen, halogen, cyano, C 1 -C 4 alkyl, or C 1 -C 4 haloalkyl; R 8 , R 14 and R 15 each independently are hydrogen or C 1 -C 4 alkyl; and R 9 is phenyl, benzyl or group (a), wherein the phenyl, benzyl and group (a) are each optionally substituted with 1 to 3 substituents independently selected from C 1 -C 4 alkyl, C 1 -C 4 haloalkyi, halogen, cyano, hydroxy and amino; or a salt or a N-oxide thereof.
    • 本发明涉及具有杀微生物活性,特别是杀真菌活性的式I的杂环化合物以及使用式(I)化合物来控制微生物的方法:其中A是xC(R10R11)-C(= O) - ,xC(R12R13)-C(= S) - ,xOC(= O) - ,xOC(= S) - ,xN(R14)-C(= O) - ,xN(R15)-C(= S) ,xC(R16R17)-SO2-或xN = C(R30) - ,在每种情况下x表示与R1连接的键; T为CR18或N; Y1,Y2,Y3和Y4独立地为CR19或N; Q是O或S; n为1或2; p为1或2,条件是当n为2时,p为1. R1为(式A)R2,R3,R4,R5,R6,R7,R10,R11,R12,R13,R16,R17,R18,R19 R 30各自独立地为氢,卤素,氰基,C 1 -C 4烷基或C 1 -C 4卤代烷基; R8,R14和R15各自独立地为氢或C1-C4烷基; 并且R 9为苯基,苄基或基团(a),其中苯基,苄基和基团(a)各自任选被1至3个独立地选自C 1 -C 4烷基,C 1 -C 4卤代烷基,卤素,氰基,羟基和 氨基; 或其盐或N-氧化物。