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31. 发明申请

US20050251011A1 Clinical trial image and data processing system 审中-公开
标题翻译：临床试验图像和数据处理系统
公开(公告)号：US20050251011A1
公开(公告)日：2005-11-10
申请号：US10945700
申请日：2004-09-21
申请人： Gudrun Zahlmann , Siegfried Schneider , Markus Schmidt
发明人： Gudrun Zahlmann , Siegfried Schneider , Markus Schmidt
IPC分类号： G06F19/00 , A61B8/00
CPC分类号： G06F19/324 , G06F19/321 , G16H10/20
摘要： A communication system connects clinical trial participants, managers, sponsors and associated systems and provides imaging-specific functions that enhance imaging systems. A patient clinical image data processing system includes an acquisition interface for acquiring patient medical image representative data from one or more sources. A processor automatically removes patient specific information from patient medical image representative data to provide patient non-specific medical image representative data and stores the patient non-specific medical image representative data. A communication interface communicates, via a network, the patient non-specific medical image representative data to a remote location.
摘要翻译：通信系统连接临床试验参与者，经理，赞助商和相关系统，并提供增强成像系统的成像特定功能。患者临床图像数据处理系统包括用于从一个或多个源获取患者医学图像代表性数据的获取界面。处理器自动地从患者医学图像代表性数据中去除患者特定信息，以提供患者非特异性医学图像代表性数据并存储患者非特异性医学图像代表性数据。通信接口经由网络将患者的非特异性医学图像代表性数据传送到远程位置。

32. 发明申请

US20050182663A1 Method of examining a plurality of sites for a clinical trial 审中-公开
标题翻译：检查用于临床试验的多个部位的方法
公开(公告)号：US20050182663A1
公开(公告)日：2005-08-18
申请号：US10975009
申请日：2004-10-28
申请人： Klaus Abraham-Fuchs , Gudrun Zahlmann , Rainer Kuth , Eva Rumpel , Siegfried Schneider , Markus Schmidt , Horst Schreiner
发明人： Klaus Abraham-Fuchs , Gudrun Zahlmann , Rainer Kuth , Eva Rumpel , Siegfried Schneider , Markus Schmidt , Horst Schreiner
IPC分类号： G06F19/00 , G06Q10/00 , G06Q30/00 , G06Q50/00 , G06F17/60
CPC分类号： G06Q30/02 , G06F19/328 , G06Q10/10 , G06Q50/24 , G16H10/20
摘要： A method is proposed for examining a plurality of sites for a clinical trial. The method includes obtaining criteria for clinical trial and determining, using a computer device, how information regarding each of a plurality of clinical trial sites relates to the obtained criteria. Based upon the determinations, a plurality of the clinical trial sites are ranked. Thereafter, the ranked clinical trial sites may be reported to a sponsor of the clinical trial, and payment may be received.
摘要翻译：提出了一种用于检查用于临床试验的多个部位的方法。该方法包括获得临床试验的标准并使用计算机设备确定关于多个临床试验部位中的每一个的信息如何与获得的标准相关。基于确定，对多个临床试验点进行排名。此后，可以向临床试验的赞助者报告排名的临床试验地点，并可以收到付款。

33. 发明申请

US20050182658A1 Method of improving a clinical study 审中-公开
标题翻译：改善临床研究的方法
公开(公告)号：US20050182658A1
公开(公告)日：2005-08-18
申请号：US10975057
申请日：2004-10-28
申请人： Klaus Abraham-Fuchs , Gudrun Zahlmann , Eva Rumpel , Siegfried Schneider , Markus Schmidt , Horst Schreiner
发明人： Klaus Abraham-Fuchs , Gudrun Zahlmann , Eva Rumpel , Siegfried Schneider , Markus Schmidt , Horst Schreiner
IPC分类号： G06F19/00 , G06F17/60
CPC分类号： G06Q50/22 , G16H10/20 , G16H40/20
摘要： A method is proposed for improving a clinical study. The method includes obtaining criteria for the clinical study, and comparing clinical data to the obtained criteria using a computer device. Thereafter, using the computer device, performance measures are derived based upon the comparisons. These derived performance measures are then usable to improve the clinical study. For example, these performance measures may be used for ranking, and consequently improving, the clinical study.
摘要翻译：提出一种改善临床研究的方法。该方法包括获得临床研究的标准，并使用计算机设备将临床数据与获得的标准进行比较。此后，使用计算机设备，基于比较导出性能测量。这些导出的绩效指标可用于改善临床研究。例如，这些性能测量可用于对临床研究进行排名，从而改善临床研究。

34. 发明申请

US20050182657A1 Method and system for measuring quality of performance and/or compliance with protocol of a clinical study 有权
标题翻译：用于测量性能质量和/或符合临床研究方案的方法和系统
公开(公告)号：US20050182657A1
公开(公告)日：2005-08-18
申请号：US10975011
申请日：2004-10-28
申请人： Klaus Abraham-Fuchs , Gudrun Zahlmann , Rainer Kuth , Eva Rumpel , Siegfried Schneider , Markus Schmidt , Horst Schreiner
发明人： Klaus Abraham-Fuchs , Gudrun Zahlmann , Rainer Kuth , Eva Rumpel , Siegfried Schneider , Markus Schmidt , Horst Schreiner
IPC分类号： G06F17/60
CPC分类号： G06Q10/06393 , G06F19/00 , G06Q30/018 , G06Q50/22 , G16H10/20 , G16H10/40 , G16H40/20
摘要： A method is proposed for determining clinical study compliance. The method includes obtaining criteria for the clinical study and accessing stored clinical data relating to the clinical study. Thereafter, the criteria and clinical data are correlated to determine a measure of compliance with the criteria of the clinical study.
摘要翻译：提出了一种确定临床研究依从性的方法。该方法包括获得临床研究的标准和访问与临床研究相关的存储的临床数据。此后，标准和临床资料相关，以确定是否符合临床研究标准。

35. 发明授权

US5152288A Apparatus and method for measuring weak, location-dependent and time-dependent magnetic fields 失效
标题翻译：用于测量弱点，位置依赖性和时间依赖磁场的装置和方法
公开(公告)号：US5152288A
公开(公告)日：1992-10-06
申请号：US774635
申请日：1991-10-09
申请人： Eckhardt Hoenig , Helmut Reichenberger , Siegfried Schneider
发明人： Eckhardt Hoenig , Helmut Reichenberger , Siegfried Schneider
IPC分类号： A61B5/04 , A61B5/05 , G01R33/00 , G01R33/035
CPC分类号： G01R33/00 , A61B5/04005 , G01R33/0354 , A61B5/0046
摘要： An apparatus for measuring weak, location-dependent and time-dependent magnetic fields emitted from a source situated in an examination subject includes a sensor arrangement having at least ten gradiometers of the first order, each gradiometer being inductively coupled to a DC-SQUID. The sensor arrangement and the examination subject are disposed in a room which shields the examination subject and the sensor arrangement from magnetic fields. The room has a shielding factor of at least 10 for magnetic alternating fields having a frequency of 0.5 Hz, the shielding factor increasing with increasing frequency. A method for operating the apparatus is also disclosed.
摘要翻译：用于测量从位于检查对象中的源发出的弱的，取决于位置的和与时间相关的磁场的装置包括具有至少十个第一级的梯度计的传感器装置，每个梯度计感应耦合到DC-SQUID。传感器装置和检查对象被设置在屏蔽检查对象和传感器装置免受磁场影响的房间中。对于频率为0.5Hz的磁场交变场，该房间屏蔽系数至少为10，屏蔽因数随着频率的增加而增加。还公开了一种操作该装置的方法。

36. 发明授权

US4200622A Purification of ammonium fluoride solutions 失效
标题翻译：氟化铵溶液的纯化
公开(公告)号：US4200622A
公开(公告)日：1980-04-29
申请号：US960329
申请日：1978-11-13
申请人： Hans Kyri , Hans-Dietrich Lauss , Siegfried Schneider
发明人： Hans Kyri , Hans-Dietrich Lauss , Siegfried Schneider
IPC分类号： C01C1/16 , C01F7/54
CPC分类号： C01F7/54 , C01C1/162
摘要： In the purification of an ammonium fluoride solution containing silicic acid by adding iron (III) ions and precipitating the iron (III) ions at a pH above 8.5 and a concentration of free ammonia in the solution of more than about 1% by weight, the silicic acid being carried with the iron (III) ion precipitate, the improvement which comprises adding the iron (III) ions to the ammonium fluoride solution at a temperature below about 30.degree. C. and, before removal of the precipitate, to the solution a salt of at least one of the alkali metals, alkaline earth metals, zinc, aluminum and lead in such quantity that the solution becomes saturated with such salt.
摘要翻译：在通过添加铁（III）离子和在高于8.5的pH下沉淀出铁（III）离子并且溶液中的游离氨浓度大于约1重量％来纯化含有硅酸的氟化铵溶液时，硅酸与铁（III）离子沉淀携带，其改进包括在低于约30℃的温度下向氟化铵溶液中加入铁（III）离子，并且在除去沉淀物之前，向溶液a 至少一种碱金属，碱土金属，锌，铝和铅的盐的量使得溶液变得饱和。

37. 发明授权

US4148867A Production of synthetic fluorspar 失效
标题翻译：生产合成萤石
公开(公告)号：US4148867A
公开(公告)日：1979-04-10
申请号：US704252
申请日：1976-07-12
申请人： Siegfried Schneider , Hans Niederprum
发明人： Siegfried Schneider , Hans Niederprum
IPC分类号： C01F11/22 , C01B33/14
CPC分类号： C01F11/22
摘要： In the production of a synthetic fluorspar of low silicon dioxide content wherein hexafluosilicic acid is added in an amount ranging from slightly below up to about stoichiometric amount to an aqueous calcium carbonate suspension at a temperature from about 0.degree. to 40.degree. C., and the calcium fluoride formed is separated off from the dilute silica sol and optionally washed out, the improvement which comprises reacting the calcium carbonate with the hexafluosilicic acid in such a way that the pH-value of the fully reacted solution amounts to between about 3.6 and 4.6, and adding a fast-reacting proton acceptor to the reaction mixture immediately before separation of the calcium fluoride in amount sufficient to raise the pH to about 5.0 to 6.4, preferably about 5.8 to 6.2. Suitable proton acceptors include the alkali metal and ammonium hydroxides carbonates and hydrogen carbonates or alkaline earth metal hydroxide. Anionic or non-ionic dispersants may also be added and the calcium fluoride is separated by decanting or centrifugation within about 1 second to 10 minutes, preferably about 4 to 10 seconds, after raising the pH. The separated calcium fluoride may be washed to remove silica sol therefrom and then again be treated to raise its pH before separation.
摘要翻译：在制备低二氧化硅含量的合成荧光粉中，其中将六氟硅酸以约低于约化学计量的量加入到约0℃至40℃的温度下的碳酸钙水溶液悬浮液中，并且形成的氟化钙与稀二氧化硅溶胶分离并任选地洗出，其改进包括使碳酸钙与六氟硅酸反应，使得完全反应的溶液的pH值达到约3.6和4.6之间，然后在将氟化钙分离出足以使pH升高至约5.0至6.4，优选约5.8至6.2之间的情况下，立即向反应混合物中加入快速反应的质子受体。合适的质子受体包括碱金属和氢氧化铵，碳酸盐和碳酸氢盐或碱土金属氢氧化物。还可以加入阴离子或非离子分散剂，并且在升高pH后，在约1秒至10分钟，优选约4至10秒内通过倾析或离心分离氟化钙。可以将分离的氟化钙洗涤以从其中除去二氧化硅溶胶，然后在分离前再次进行处理以提高其pH。

38. 发明授权

US4055879A Roller 失效
标题翻译：滚筒
公开(公告)号：US4055879A
公开(公告)日：1977-11-01
申请号：US689856
申请日：1976-05-25
申请人： Siegfried Schneider , Kurt Thate , Erwin Geyken , Horst Kempe , Stephan Macher
发明人： Siegfried Schneider , Kurt Thate , Erwin Geyken , Horst Kempe , Stephan Macher
IPC分类号： B29D99/00 , F16C13/00 , G03D3/13 , B21B31/08
CPC分类号： B29D99/0035 , F16C13/00 , G03D3/13 , B29L2031/324
摘要： A roller to be used in apparatus for wet treatment of photographic material comprises a hollow metallic core and two inserts with coupling shafts provided therein. A coat of chemically resistant thermoplastic material is applied around and sealingly surrounds the core to protect it from the corrosive action of media used in the wet treatment process. The outer surface of the thus coated roller is thereupon machined to a high-quality finish.
摘要翻译：用于照相材料湿处理的设备中使用的辊子包括中空金属芯和其中设置有联接轴的两个插入件。一层耐化学腐蚀的热塑性材料被涂覆在芯上并密封地围绕芯部，以防止其在湿处理过程中使用的介质的腐蚀作用。这样涂覆的辊的外表面被加工成高质量的表面。

39. 发明授权

US09243000B2 Thia-triaza-indacenes 有权
公开(公告)号：US09243000B2
公开(公告)日：2016-01-26
申请号：US13265241
申请日：2010-04-22
申请人： Lars Van Der Veen , Darryl McConnell , Siegfried Schneider , Matthias Grauert , Andreas Schoop , Tobias Wunberg
发明人： Lars Van Der Veen , Darryl McConnell , Siegfried Schneider , Matthias Grauert , Andreas Schoop , Tobias Wunberg
IPC分类号： C07D513/04 , A61K31/381 , C07D513/14
CPC分类号： C07D513/04 , C07D513/14
摘要： The present invention encompasses compounds of general formula (1) wherein R1 to R3 and X are defined as in claim 1, which are suitable for the treatment of diseases characterized by excessive or abnormal cell proliferation, and the use thereof for preparing a medicament having the above-mentioned properties.
摘要翻译：本发明包括通式（1）的化合物，其中R 1至R 3和X如权利要求1中所定义，其适用于治疗以细胞增殖过度或异常为特征的疾病，以及其用于制备具有上述属性。

40. 发明授权

US09152939B2 Method and system for measuring quality of performance and/or compliance with protocol of a clinical study 有权
标题翻译：用于测量性能质量和/或符合临床研究方案的方法和系统
公开(公告)号：US09152939B2
公开(公告)日：2015-10-06
申请号：US13895566
申请日：2013-05-16
申请人： Klaus Abraham-Fuchs , Gudrun Zahlmann , Rainer Kuth , Eva Rumpel , Siegfried Schneider , Markus Schmidt , Horst Schreiner
发明人： Klaus Abraham-Fuchs , Gudrun Zahlmann , Rainer Kuth , Eva Rumpel , Siegfried Schneider , Markus Schmidt , Horst Schreiner
IPC分类号： G06Q10/00 , G06Q50/00 , G06Q30/00 , G06Q50/22 , G06F19/00 , G06Q10/06
CPC分类号： G06Q10/06393 , G06F19/00 , G06Q30/018 , G06Q50/22 , G16H10/20 , G16H10/40 , G16H40/20
摘要： A method is proposed for determining clinical study compliance. The method includes obtaining criteria for the clinical study and accessing stored clinical data relating to the clinical study. Thereafter, the criteria and clinical data are correlated to determine a measure of compliance with the criteria of the clinical study.
摘要翻译：提出了一种确定临床研究依从性的方法。该方法包括获得临床研究的标准和访问与临床研究相关的存储的临床数据。此后，标准和临床资料相关，以确定是否符合临床研究标准。

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