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31. 发明申请

US20080226694A1 Method for introducing superhydrophobic articles into the human body 审中-公开
标题翻译：将超疏水制品引入人体内的方法
公开(公告)号：US20080226694A1
公开(公告)日：2008-09-18
申请号：US11717071
申请日：2007-03-13
申请人： Daniel Gelbart , Samuel Victor Lichtenstein
发明人： Daniel Gelbart , Samuel Victor Lichtenstein
IPC分类号： A61L27/40
CPC分类号： A61L31/14 , A61L31/08
摘要： An article to be inserted into the human body has a superhydrophobic surface. The superhydrophobic surface is coated with a water soluble thin but durable protective coat. One positioned inside the body the coating is rapidly dissolved by the blood or other fluids and exposes the superhydrophobic surface. To coat article the water based coating is mixed with a liquid capable of wetting the superhydrophobic surface but is still dissolvable or at least miscible in the coating. As an example, a glucose or sucrose solution in water is mixed with alcohol and used to coat the surface. After water and alcohol evaporation, a durable protective coat of sugar remains. After the coated article is inserted into the body, the coating is rapidly dissolved and absorbed by the body.
摘要翻译：插入人体的物品具有超疏水性表面。超疏水表面涂有水溶性薄而耐用的防护涂层。一个位于体内的涂层被血液或其它流体迅速溶解并暴露出超疏水表面。为了涂覆物品，将水基涂层与能够润湿超疏水表面的液体混合，但是仍然可溶或至少可混溶于涂层中。例如，将水中的葡萄糖或蔗糖溶液与醇混合并用于涂覆该表面。水和酒精蒸发后，保留一层耐用的保护性糖。将涂层制品插入体内后，涂层迅速溶解并被身体吸收。

32. 发明申请

US20080133002A1 Inflatable artificial valve 审中-公开
标题翻译：充气人造阀
公开(公告)号：US20080133002A1
公开(公告)日：2008-06-05
申请号：US11633447
申请日：2006-12-05
申请人： Daniel Gelbart , Samuel Victor Lichtenstein
发明人： Daniel Gelbart , Samuel Victor Lichtenstein
IPC分类号： A61F2/24 , A61F2/02
CPC分类号： A61F2/2427 , A61F2/2412 , A61F2/2415 , A61F2250/0003 , A61L27/50 , A61L27/507
摘要： An artificial valve is delivered percutaneously in the form of a hollow inflatable shell, which is later filled in situ with a suitable elastomer, similar to inflating a balloon. Since the shell is a flexible and mostly hollow balloon, it can be compressed and transported via a relatively small catheter. In order to inflate to the correct shape the hollow shell requires some ties between its walls. These ties are formed from a low density open cell foam or a specialized manufacturing process. The valve can combine elements with different stiffness as well as different materials. A positioning balloon can also be used in the process of placing the valve. The invention is particularly suited for cardiac valves but can be used for other artificial valves.
摘要翻译：人造瓣膜以中空充气外壳的形式经皮输送，后者用合适的弹性体原位填充，类似于使气囊膨胀。由于外壳是柔性且大部分为空心球囊，因此可通过较小的导管将其压缩和运输。为了充气到正确的形状，中空的外壳需要其壁之间的一些连接。这些连接由低密度开孔泡沫或专门的制造工艺形成。阀门可以组合具有不同刚度和不同材料的元件。在放置阀门的过程中也可以使用定位气囊。本发明特别适用于心脏瓣膜，但可用于其他人造瓣膜。

33. 发明申请

US20080033541A1 Artificial mitral valve 审中-公开
标题翻译：人造二尖瓣
公开(公告)号：US20080033541A1
公开(公告)日：2008-02-07
申请号：US11497306
申请日：2006-08-02
申请人： Daniel Gelbart , Samuel Victor Lichtenstein
发明人： Daniel Gelbart , Samuel Victor Lichtenstein
IPC分类号： A61F2/24
CPC分类号： A61F2/2412 , A61F2/2418 , A61F2/2436 , A61F2/246
摘要： An artificial mitral valve is made of a short piece of elastomeric tubing having a one round end and one flattened end. The tubing can be rolled up to a small diameter and fits snuggly into the mitral valve opening when expanded. The tubing attaches to a few rings made of thin flexible wire. When the rings are expanded inside the left atrium, they form a support structure holding the artificial valve in the correct position. The rings can be flattened and delivered via a catheter together with the valve. The artificial valve contains no rigid component, therefore it does not deform or damage the area around the defective mitral valve and can be installed even in highly calcified or deteriorated valves.
摘要翻译：人造二尖瓣由具有一个圆形端部和一个扁平端部的短的弹性管制成。管道可以卷起到一个小直径，并扩张时适合紧贴二尖瓣开口。管道连接到由薄柔性线制成的几个环。当环在左心房内扩张时，它们形成将人造瓣保持在正确位置的支撑结构。环可以与阀一起通过导管扁平化并输送。人造瓣膜不含刚性部件，因此不会使二尖瓣不正周围的区域发生变形或损伤，即使在高度钙化或变质的阀门中也能安装。

34. 发明申请

US20070270688A1 Automatic atherectomy system 审中-公开
标题翻译：自动粥样斑块切除术
公开(公告)号：US20070270688A1
公开(公告)日：2007-11-22
申请号：US11436584
申请日：2006-05-19
申请人： Daniel Gelbart , Samuel Victor Lichtenstein
发明人： Daniel Gelbart , Samuel Victor Lichtenstein
IPC分类号： A61B5/05
CPC分类号： A61B5/053 , A61B5/0538 , A61B17/320758 , A61B2017/00022 , A61B2017/00026 , A61B2017/00084 , A61B2017/003 , A61B2017/00539 , A61B2017/320004
摘要： An automatic atherectomy system uses the rotary burr at the tip of a catheter as a sensing device, in order to measure both the electrical conductivity and permittivity of the surrounding tissue at multiple frequencies. From these parameters it is determined which tissue lies in the different directions around the tip. A servo system steers the catheter tip in the direction of the tissue to be removed. In non-atherectomy applications the rotary tip can be replaced with any desired tool and the system can be used to automatically steer the catheter to the desired position. The steering is done hydraulically, by pressurizing miniature bellows located near the catheter tip.
摘要翻译：自动斑块切除系统使用导管末端的旋转毛刺作为感测装置，以便测量多个频率下周围组织的电导率和介电常数。根据这些参数，确定哪个组织位于尖端周围的不同方向上。伺服系统沿着要移除的组织的方向引导导管尖端。在非粥样斑块切除术应用中，旋转尖端可以用任何所需的工具替代，并且系统可用于自动地将导管转向所需位置。通过对位于导管尖端附近的微型波纹管进行加压，液压转向。

35. 发明授权

US09744038B2 Medical device for constricting tissue or a bodily orifice, for example a mitral valve 有权
公开(公告)号：US09744038B2
公开(公告)日：2017-08-29
申请号：US12899407
申请日：2010-10-06
申请人： Jon Dahlgren , Doug Goertzen , Daniel Gelbart
发明人： Jon Dahlgren , Doug Goertzen , Daniel Gelbart
IPC分类号： A61M31/00 , A61F2/24 , A61B17/04 , A61B17/00 , A61B17/22
CPC分类号： A61F2/2445 , A61B17/0401 , A61B17/0469 , A61B17/0485 , A61B2017/00331 , A61B2017/0409 , A61B2017/0437 , A61B2017/0441 , A61B2017/0464 , A61B2017/0496 , A61B2017/22038 , A61F2/2454
摘要： A medical apparatus positionable in a cavity of a bodily organ (e.g., a heart) may constrict a bodily orifice (e.g., a mitral valve). The medical apparatus may include tissue anchors that are implanted in the annulus of the orifice. The tissue anchors may be guided into position by an intravascularly or percutaneously deployed anchor guiding frame. Constriction of the orifice may be accomplished by cinching a flexible cable attached to implanted tissue anchors. The medical device may be used to approximate the septal and lateral (clinically referred to as anterior and posterior) annulus of the mitral valve in order to move the posterior leaflet anteriorly and the anterior leaflet posteriorly and thereby improve leaflet coaptation and eliminate mitral regurgitation.

36. 发明授权

US08979776B2 Lithotripsy system with automatic 3D tracking 有权
公开(公告)号：US08979776B2
公开(公告)日：2015-03-17
申请号：US12289717
申请日：2008-11-03
申请人： Daniel Gelbart , Lindsay Machan
发明人： Daniel Gelbart , Lindsay Machan
IPC分类号： A61H1/00 , A61B17/225 , A61B17/22
CPC分类号： A61B17/225 , A61B17/2251 , A61B17/2256 , A61B2017/22028
摘要： A lithotripsy system capable of 3D tracking monitors the acoustic reflection from the stone in order to focus the shock wave on the stone regardless of shock wave displacement or stone movement. The tracking and focusing is based on a phased array concept, allowing the lithotripsy head to remain stationary and well coupled to the body. An alternate shock wave steering is based on refraction by a variable liquid wedge.

37. 发明授权

US08615856B1 Apparatus and method for forming self-retaining sutures 有权
标题翻译：用于形成自固定缝线的装置和方法
公开(公告)号：US08615856B1
公开(公告)日：2013-12-31
申请号：US12363582
申请日：2009-01-30
申请人： Daniel Gelbart
发明人： Daniel Gelbart
IPC分类号： B21F25/00 , A61B17/04
CPC分类号： B21F25/00 , A61B17/06166 , A61B2017/00526 , A61B2017/06176 , B21F45/008 , D02G3/448 , D02J3/00 , Y10T29/20
摘要： An apparatus and method for forming retainers on a continuous strand such as, for example, of suture material and a suture produced by the same. The apparatus may include a retainer forming member configured to rotate about a first axis. The retainer forming member may include a cutter, the cutting edge of which may directed substantially inward toward, or outward away from, the first axis to define a retainer forming zone when the retainer forming member rotates about the first axis. The apparatus may further include a support member arranged adjacent to the retainer forming member and configured to receive and support the continuous strand in the retainer forming zone. When the retainer forming member rotates about the first axis, the passing strand may be intermittently or continuously cut by the cutting edge of the cutter.
摘要翻译：一种用于在连续股线上形成保持器的装置和方法，例如缝合材料和由其制成的缝合线。该装置可以包括构造成围绕第一轴线旋转的保持器形成构件。保持器形成构件可以包括切割器，其切割边缘可以朝着第一轴线或向外远离第一轴线指向，以在保持器形成构件围绕第一轴线旋转时限定保持器成形区域。该装置还可以包括邻近保持器形成构件设置并构造成在保持器成形区域中接收和支撑连续线材的支撑构件。当保持器形成构件围绕第一轴线旋转时，通过的线可以由切割器的切割边缘间歇地或连续地切割。

38. 发明申请

US20130226148A1 Mixing syringe 有权
标题翻译：混合注射器
公开(公告)号：US20130226148A1
公开(公告)日：2013-08-29
申请号：US13385627
申请日：2012-02-28
申请人： Lindsay S. Machan , Daniel Gelbart
发明人： Lindsay S. Machan , Daniel Gelbart
IPC分类号： A61M5/31
CPC分类号： A61M5/31596 , A61M2005/31516 , A61M2005/31598 , A61M2205/7545
摘要： A movable mixing disc is inserted into a regular syringe. The mixing disc has a small hole covered by a fine screen, allowing only saline solution to get behind the disc. When the plunger of the syringe is pressed, the saline solution emerges from the mixing disc hole as a high velocity jet, stirring up the settled particles. As the ejection continues, the mixing disc is pushed forward by the plunger in order to eliminate any unused volume.
摘要翻译：将可动混合盘插入常规注射器中。混合盘具有被细筛网覆盖的小孔，只允许盐水溶液到达盘后。当注射器的柱塞被按压时，盐溶液作为高速喷射从混合盘孔中排出，搅拌沉降的颗粒。当喷射继续时，混合盘被柱塞向前推动，以消除任何未使用的体积。

39. 发明申请

US20120215095A1 X-Ray radiation reduction system 审中-公开
标题翻译： X射线辐射降低系统
公开(公告)号：US20120215095A1
公开(公告)日：2012-08-23
申请号：US13385402
申请日：2012-02-21
申请人： Amit Mordechai Av-Shalom , Meir Deutsch , Daniel Gelbart
发明人： Amit Mordechai Av-Shalom , Meir Deutsch , Daniel Gelbart
IPC分类号： A61B6/00 , A61B6/08
CPC分类号： A61B6/4441 , A61B6/06 , A61B6/405 , A61B6/469 , A61B6/487 , A61B6/542
摘要： By exposing the ROI at full exposure and full frame rate while exposing the area outside the ROI with low exposure and up to full frame rate an overall reduction in X-Ray radiation is achieved. The resultant image has slightly lower resolution outside the ROI but better resolution (as compared to standard fluoroscopy practices) in the ROI because of reduced scattering. Different exposures are supplied to different parts of the image by using a fast shutter in conjunction with the exposure control.
摘要翻译：通过在全曝光和全帧速率下曝光ROI，同时以低曝光和高达全帧速率曝光ROI外部的区域，实现了X射线辐射的全面减少。所得到的图像在ROI之外具有略低的分辨率，但是由于散射减少，ROI中的分辨率（与标准荧光透视实践相比）更好。通过使用快门与曝光控制相结合，将不同的曝光提供给图像的不同部分。

40. 发明授权

US07983391B2 System for reduction of exposure to X-ray radiation 有权
标题翻译：用于减少暴露于X射线辐射的系统
公开(公告)号：US07983391B2
公开(公告)日：2011-07-19
申请号：US12386895
申请日：2009-04-27
申请人： Lindsay S. Machan , Daniel Gelbart
发明人： Lindsay S. Machan , Daniel Gelbart
IPC分类号： H05G1/64 , G21K1/04
CPC分类号： G21K1/04 , A61B6/06 , A61B6/12 , A61B6/4441 , A61B6/504 , G21K1/043
摘要： To reduce X-ray exposure, an area of interest is selected in the image. The image of the selected area is updated frequently, comparable to rate of updates used today for the whole image. The rest of the image is updated at a significantly lower rate. Since the area of interest normally is a small part of the overall area, the total exposure is reduced significantly. A movable X-ray shield placed near the X-ray source blocks the radiation from areas outside the area of interest. The shield automatically retracts when the complete image is updated. The area of interest can be selected by the user or automatically selected based on activity in the image.
摘要翻译：为了减少X射线曝光，图像中选择感兴趣区域。所选区域的图像经常更新，与整个图像当前使用的更新速率相当。图像的其余部分以显着较低的速率更新。由于感兴趣的区域通常是整个区域的一小部分，因此总体暴露量显着降低。放置在X射线源附近的可移动的X射线屏蔽物阻挡来自感兴趣区域外的区域的辐射。完整的图像更新后，屏幕会自动缩回。感兴趣区域可以由用户选择或根据图像中的活动自动选择。

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