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31. 发明申请

US20060253037A1 Locator and closure device and method of use 有权
公开(公告)号：US20060253037A1
公开(公告)日：2006-11-09
申请号：US11244944
申请日：2005-10-05
申请人： Richard Ginn , Thomas Palermo
发明人： Richard Ginn , Thomas Palermo
IPC分类号： A61B5/02
CPC分类号： A61B17/0057 , A61B2017/00654 , A61B2017/00672 , A61B2017/2923 , A61B2090/0807
摘要： The present invention is directed to a device which is capable of both locating a punctured blood vessel wall and sealing the puncture in the vessel and to the method of using the device as well. In one embodiment, the device includes an elongate deployment member having a sealing element releasably disposed within a distal end thereof, said deployment member being coupled to a first actuator configured to retract said deployment member relative to said sealing element, and an elongated indicator member having a proximal end and a distal end, said indicator member extending through a lumen in said deployment member such that the distal end of said indicator member extends distally of the distal end of the deployment member, and said indicator member being coupled to a second actuator configured to retract said indicator member relative to said deployment member.

32. 发明申请

US20060212071A1 Systems and Methods for Closing Internal Tissue Defects 审中-公开
标题翻译：关闭内部组织缺陷的系统和方法
公开(公告)号：US20060212071A1
公开(公告)日：2006-09-21
申请号：US11422869
申请日：2006-06-07
申请人： Richard Ginn , Joseph Karratt
发明人： Richard Ginn , Joseph Karratt
IPC分类号： A61B17/08
CPC分类号： A61B17/0057 , A61B17/0644 , A61B17/068 , A61B17/08 , A61B17/1227 , A61B90/39 , A61B2017/00575 , A61B2017/00592 , A61B2017/00606 , A61B2017/00623 , A61B2017/00867 , A61B2017/061 , A61B2017/0649
摘要： A delivery system having a steerable delivery device and an elastic clip for treating an internal tissue defect, such as septal defects and the like, is provided. The clip can be deformable between a relaxed state and a stressed state and biased towards the relaxed state. The delivery device can include a flexible tubular needle with a lumen for housing the clip while in the stressed state. When used to treat a septal defect, the needle is advancable through overlapping tissue flaps and a pusher member is advancable within the needle lumen to push the clip distally such that one end of the clip is deployed and engages a tissue flap. The needle can then be retracted allowing the clip to deploy over both flaps of tissue, where the biasing force returns the clip to the relaxed state drawing the tissue flaps together and closing the septal defect.
摘要翻译：提供了一种具有可转向递送装置和用于治疗内部组织缺陷（例如间隔缺损等）的弹性夹具的递送系统。夹子可以在松弛状态和应力状态之间变形，并且朝向松弛状态偏置。递送装置可以包括具有内腔的柔性管状针，以在处于应力状态时容纳夹子。当用于治疗间隔缺损时，针可以通过重叠的组织瓣来推动，并且推动器构件可在针内腔内推进以向远侧推动夹子，使得夹子的一端展开并接合组织瓣。然后针可以缩回，使得夹子能够在组织的两个翼片上展开，其中偏置力将夹子返回到松弛状态，将组织瓣片拉在一起并闭合间隔缺损。

33. 发明申请

US20060144479A1 Methods for manufacturing a clip and clip 有权
标题翻译：制造夹子和夹子的方法
公开(公告)号：US20060144479A1
公开(公告)日：2006-07-06
申请号：US10541083
申请日：2003-12-17
申请人： Michael Carley , Richard Ginn
发明人： Michael Carley , Richard Ginn
IPC分类号： C22F1/00
CPC分类号： A61B17/068 , A61B17/0057 , A61B17/064 , A61B17/0644 , A61B17/083 , A61B90/39 , A61B2017/00004 , A61B2017/00867 , C22C19/007 , C22F1/00 , C22F1/10 , C22F1/16
摘要： The present invention relates to a method of making clips which can be used to engage body tissue for the purpose of closing wounds. Such clips are generally annular in shape and have radially inwardly extending tines. The present invention first forms a precursor which, in one embodiment, has the tines extending radially outwardly from the annular body and then forms the clip by inverting the precursor such that the tines extend radially inwardly. In an alternate embodiment, the precursor is formed with an over-sized lateral dimension and then compressed inwardly to bring the tines closer A together and to reduce the lateral dimension of the precursor. It is preferred to manufacture such clips from a superelastic alloy such as nickel-titanium, in which case the inverted or compressed precursor must be heated and quenched to heat set the clip in its final shape.
摘要翻译：本发明涉及一种制造夹子的方法，该夹具可用于接合身体组织以便关闭伤口。这种夹子通常是环形的并且具有径向向内延伸的尖齿。本发明首先形成前体，在一个实施方案中，前体具有从环形体径向向外延伸的齿，然后通过倒转前体形成夹子，使得尖齿径向向内延伸。在替代实施例中，前体形成为具有过大尺寸的侧向尺寸，然后被向内压缩以使尖齿更靠近在一起并减小前体的横向尺寸。优选从诸如镍钛的超弹性合金制造这种夹子，在这种情况下，必须加热和淬火反转或压缩的前体以将夹子热定型成其最终形状。

34. 发明申请

US20050273137A1 Apparatus and methods for sealing vascular punctures 有权
标题翻译：用于密封血管穿刺的装置和方法
公开(公告)号：US20050273137A1
公开(公告)日：2005-12-08
申请号：US11200459
申请日：2005-08-08
申请人： Richard Ginn
发明人： Richard Ginn
IPC分类号： A61B17/08 , A61B10/00 , A61B17/00 , A61B17/12
CPC分类号： A61B17/0057 , A61B2010/0003 , A61B2017/00004 , A61B2017/00637 , A61B2017/00654 , A61B2017/00898
摘要： An apparatus for sealing a passage through tissue communicating with a blood vessel includes a bioabsorbable plug member coupled to the distal end of a carrier member. The plug member includes a lumen extending therethrough that communicates with a lumen extending through the carrier member. A sealing member is disposed in the plug member lumen for sealing the lumen. A guide member is slidable into the lumen such that edges of a groove extending between proximal and distal portions of the guide member engage a wall of the lumen to define a bleed back lumen. The guide member is inserted into the passage until the distal portion enters the vessel. The plug member is advanced over the guide member until the plug member enters the vessel, whereupon blood enters the bleed back lumen to identify the location of the vessel relative to the plug member.
摘要翻译：用于密封通过与血管连通的组织的通道的装置包括联接到载体构件的远端的生物可吸收塞构件。插塞构件包括延伸穿过其中的内腔，其与延伸穿过承载构件的内腔连通。密封构件设置在塞构件内腔中，用于密封管腔。引导构件可滑动到内腔中，使得在引导构件的近端部分和远端部分之间延伸的凹槽的边缘接合腔的壁以限定出血腔。引导构件插入通道中，直到远端部分进入血管。插塞构件在引导构件上前进直到插塞构件进入容器，于是血液进入排泄腔，以识别容器相对于插塞构件的位置。

35. 发明申请

US20050267528A1 Vascular plug having composite construction 有权
标题翻译：具有复合结构的血管塞
公开(公告)号：US20050267528A1
公开(公告)日：2005-12-01
申请号：US11038995
申请日：2005-01-19
申请人： Richard Ginn , Thomas Palermo , Phil Olsen , Tellis Hartridge , Adam Shively
发明人： Richard Ginn , Thomas Palermo , Phil Olsen , Tellis Hartridge , Adam Shively
IPC分类号： A61B17/00 , A61B17/08
CPC分类号： A61B17/0057 , A61B17/12022 , A61B17/12109 , A61B17/12159 , A61B17/12163 , A61B17/12172 , A61B17/1219 , A61B2017/00004 , A61B2017/00654 , A61B2017/00778 , A61B2017/00898
摘要： This invention relates to apparatus and methods for use in sealing a vascular puncture site, particularly sites of punctures that are the result of catheterization or other interventional procedures. In several of the preferred embodiments, the sealing device includes a sealing member and a tether. The sealing member generally performs the function of occupying a space in an incision, puncture, or other wound and sealing the space in the incision, puncture, or wound that it occupies, to prevent further blood flow. The tether is typically attached in some manner to the sealing member, and provides the user with the ability to withdraw the sealing member if necessary. In a particularly preferred form, the sealing device further includes a restraining member associated with the sealing member. The restraining member provides the ability to more securely restrain the sealing member to prevent it from migrating from the deployment location within a tissue tract. The restraining member may also provide an additional capability of manipulating the sealing member after deployment.
摘要翻译：本发明涉及用于密封血管穿刺部位的装置和方法，特别是作为导管插入术或其他介入手术的结果的穿刺部位。在几个优选实施例中，密封装置包括密封构件和系绳。密封构件通常执行占据切口，穿刺或其他伤口中的空间并密封其占据的切口，穿刺或伤口中的空间的功能，以防止进一步的血液流动。系绳通常以某种方式附接到密封构件上，并且如果需要，使用者能够抽出密封构件。在特别优选的形式中，密封装置还包括与密封构件相关联的限制构件。限制构件提供了更可靠地限制密封构件以防止其从组织道内的展开位置迁移的能力。限制构件还可以在部署之后提供操纵密封构件的附加能力。

36. 发明申请

US20050203617A1 Prosthetic heart valves, scaffolding structures, and systems and methods for implantation of same 失效
公开(公告)号：US20050203617A1
公开(公告)日：2005-09-15
申请号：US11066126
申请日：2005-02-25
申请人： David Forster , Scott Heneveld , Brandon Walsh , Richard Ginn
发明人： David Forster , Scott Heneveld , Brandon Walsh , Richard Ginn
IPC分类号： A61F2/04 , A61F2/06 , A61F2/24
CPC分类号： A61F2/2427 , A61F2/2418 , A61F2/243 , A61F2/2433 , A61F2/2436 , A61F2/2439 , A61F2220/0008 , A61F2220/0016 , A61F2220/0033 , A61F2220/005 , A61F2220/0091 , A61F2230/0013 , A61F2230/005 , A61F2230/0091 , A61F2250/001 , A61F2250/006 , A61F2250/0063
摘要： Prosthetic valves and their component parts are described, as are prosthetic valve delivery devices and methods for their use. The prosthetic valves are particularly adapted for use in percutaneous aortic valve replacement procedures. The delivery devices are particularly adapted for use in minimally invasive surgical procedures.

37. 发明申请

US20050125076A1 Lung assist apparatus and methods for use 失效
公开(公告)号：US20050125076A1
公开(公告)日：2005-06-09
申请号：US11016409
申请日：2004-12-17
申请人： Richard Ginn
发明人： Richard Ginn
IPC分类号： A61F2/00 , A61F2/04 , A61F2/06 , A61F2/24 , A61F2/82
CPC分类号： A61F2/04 , A61F2/00 , A61F2/07 , A61F2/24 , A61F2/852 , A61F2002/043 , A61F2002/065 , A61F2002/821 , A61F2250/0063 , A61M16/0406
摘要： A lung-assist apparatus includes a tubular housing, a tubular nozzle therein, and a first valve disposed between the housing and nozzle. The housing is implanted across a bifurcation such that the nozzle extends from a first branch communicating with a healthy region of a lung towards a main passage, and terminates proximate a lateral opening in the housing that is disposed within a second branch communicating with a damaged region of the lung. During inhalation, the first valve opens to allow air flow into the first branch, and closes during exhalation to force air through the nozzle, thereby inducing a vacuum for drawing air from the damaged region. A second valve in the second branch opens during exhalation to draw air from the diseased region, and closes during inhalation to prevent air from being drawn into the damaged region.

38. 发明授权

US5458584A Intravascular catheter having an enclosed proximal end and a reduced profile distal region 失效
标题翻译：血管内导管具有封闭的近端和缩小的轮廓远侧区域
公开(公告)号：US5458584A
公开(公告)日：1995-10-17
申请号：US183458
申请日：1994-01-18
申请人： Richard Ginn , Yue-Teh Jang
发明人： Richard Ginn , Yue-Teh Jang
IPC分类号： A61B17/00 , A61B8/06 , A61B8/14 , A61B17/22 , A61B18/24 , A61B19/00 , A61M25/00 , A61M5/178
CPC分类号： A61B8/06 , A61B17/22 , A61B8/12 , A61B8/445 , A61M25/09041 , A61B17/3207 , A61B18/245 , A61B2017/22009 , A61B2017/22038 , A61B2017/22072 , A61B2017/22082 , A61B2090/378 , A61M2025/0183
摘要： The present invention provides improvement usable with an intravascular catheter having a single common distal lumen with a reduced profile connected to two or more proximal lumens. The catheter will be loadable over a guidewire into a region of interest within a patient's vascular system. According to one aspect of the present invention, means are provided to ensure that the guidewire enters into a desired one of the proximal lumens. In a preferred embodiment, a special tool is provided to achieve this. According to a second aspect of the present invention, the catheter is provided with a proximal housing and an axially expandable member to shield the rotating parts at the proximal end of the catheter and to allow for convenient movement of a work element within the catheter body.
摘要翻译：本发明提供可用于具有连接到两个或更多个近端内腔的减小轮廓的单个共同远侧内腔的血管内导管的改进。导管将可以通过导丝加载到患者血管系统内的感兴趣区域中。根据本发明的一个方面，提供了用于确保导丝进入近端内腔中所需的一个的装置。在优选实施例中，提供了一种特殊工具来实现这一点。根据本发明的第二方面，导管设置有近端壳体和可轴向扩张的构件，以在导管的近端处屏蔽旋转部分并且允许工件在导管主体内方便地移动。

39. 发明授权

US08430925B2 Prosthetic heart valves, scaffolding structures, and systems and methods for implantation of same 失效
公开(公告)号：US08430925B2
公开(公告)日：2013-04-30
申请号：US11066126
申请日：2005-02-25
申请人： David C. Forster , Scott Heneveld , Brandon Walsh , Richard Ginn
发明人： David C. Forster , Scott Heneveld , Brandon Walsh , Richard Ginn
IPC分类号： A61F2/24
CPC分类号： A61F2/2427 , A61F2/2418 , A61F2/243 , A61F2/2433 , A61F2/2436 , A61F2/2439 , A61F2220/0008 , A61F2220/0016 , A61F2220/0033 , A61F2220/005 , A61F2220/0091 , A61F2230/0013 , A61F2230/005 , A61F2230/0091 , A61F2250/001 , A61F2250/006 , A61F2250/0063
摘要： Prosthetic valves and their component parts are described, as are prosthetic valve delivery devices and methods for their use. The prosthetic valves are particularly adapted for use in percutaneous aortic valve replacement procedures. The delivery devices are particularly adapted for use in minimally invasive surgical procedures.

40. 发明授权

US08419772B2 Systems, methods and devices for correcting spinal deformities 失效
标题翻译：用于矫正脊柱畸形的系统，方法和装置
公开(公告)号：US08419772B2
公开(公告)日：2013-04-16
申请号：US12795975
申请日：2010-06-08
申请人： Matthew Thompson , Hiram Chee , Richard Ginn , Darin Gittings , Ivan Sepetka , David White
发明人： Matthew Thompson , Hiram Chee , Richard Ginn , Darin Gittings , Ivan Sepetka , David White
IPC分类号： A61B17/70
CPC分类号： A61B17/70 , A61B17/7004 , A61B17/701 , A61B17/7019 , A61B17/7025 , A61B17/7028 , A61B17/7031 , A61B17/7049 , A61B17/7068 , A61B17/707 , A61B17/809 , A61B2017/00867
摘要： Provided herein are systems, devices and methods for the correction of spinal deformities with the use one or more implantable rods configured to apply a corrective force to the spine. Methods of minimally invasive implantation of a corrective system are provided, such as where the corrective system is attached only to the spinous process of one or more vertebral bodies. Various corrective systems as well as components thereof are also provided, such as those that allow limited movement with respect to the spinal column.
摘要翻译：本文提供了用于使用一个或多个被配置为向脊柱施加矫正力的可植入杆来校正脊柱畸形的系统，装置和方法。提供了一种矫正系统的微创植入方法，例如矫正系统仅与一个或多个椎体的棘突相连的部位。还提供了各种校正系统及其部件，例如允许相对于脊柱有限运动的那些。

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