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31. 发明申请

US20080281350A1 Aneurysm Occlusion Devices 审中-公开
标题翻译：动脉瘤闭塞装置
公开(公告)号：US20080281350A1
公开(公告)日：2008-11-13
申请号：US11956323
申请日：2007-12-13
申请人： Ivan Sepetka , Greg Mirigian , Arindam Datta , Steven Hochberg , Ricardo Aboytes , Trang Ngo
发明人： Ivan Sepetka , Greg Mirigian , Arindam Datta , Steven Hochberg , Ricardo Aboytes , Trang Ngo
IPC分类号： A61M29/02
CPC分类号： A61B17/12022 , A61B17/0057 , A61B17/12113 , A61B17/12145 , A61B17/12172 , A61B17/12181 , A61B2017/00575 , A61B2017/00592 , A61B2017/00606 , A61B2017/00615 , A61B2017/00619 , A61B2017/12054 , A61B2017/12095 , A61M2025/0042
摘要： An implantable occlusion device for bridging the neck of an aneurysm comprises a biocompatible matrix. The device is movable between a compressed position prior to implantation and a generally concave or cup-shaped position following implantation. The device may comprise a frame having a plurality of elements. The frame elements have a first pre-deployment position generally parallel to a major axis of the delivery lumen, and a second post-deployment position spread radially from the major axis of the delivery lumen. The biocompatible matrix and/or the frame elements may also form or be manipulated to form a generally concave or cupped shape. The matrix can be porous or semiporous, such as a foam or a reticulated matrix. The occlusion device can be folded, twisted and/or stretched to adopt a narrow profile for loading into a coaxial delivery device and expand in place as it adopts its original shape on release. The device may be released or manipulated to a desired shape to occlude an aneurysm. Methods of using the implantable device are also provided.
摘要翻译：用于桥接动脉瘤颈部的可植入闭塞装置包括生物相容性基质。该装置可在植入之前的压缩位置和植入后的大致凹形或杯状位置之间移动。该装置可以包括具有多个元件的框架。框架元件具有大致平行于输送腔的长轴的第一预部署位置和从输送腔的长轴径向扩展的第二后部署位置。生物相容性基质和/或框架元件也可以形成或被操作以形成大体上凹形或杯状的形状。基质可以是多孔的或半孔的，例如泡沫或网状基质。闭塞装置可以被折叠，扭曲和/或拉伸以采用狭窄的轮廓以装载到同轴输送装置中，并且在释放时采用其原始形状而扩展就位。该装置可以被释放或操纵到期望的形状以阻塞动脉瘤。还提供了使用可植入装置的方法。

32. 发明申请

US20080234706A1 Systems, methods and devices for removing obstructions from a blood vessel 审中-公开
公开(公告)号：US20080234706A1
公开(公告)日：2008-09-25
申请号：US12008108
申请日：2008-01-07
申请人： Ivan Sepetka , Martin Dieck , Son Gia , John Miller , Ryan Pierce , Maria Aboytes , Tiffany Tran Ngo
发明人： Ivan Sepetka , Martin Dieck , Son Gia , John Miller , Ryan Pierce , Maria Aboytes , Tiffany Tran Ngo
IPC分类号： A61B17/22
CPC分类号： A61B17/221 , A61B17/22031 , A61B18/1492 , A61B2017/22034 , A61B2017/2212 , A61B2017/2215 , A61B2017/2217 , A61B2018/00214 , A61B2018/00898 , A61F2/013 , A61F2002/016 , A61F2002/018 , A61F2230/0091 , A61M25/0068 , A61M25/0074 , A61M25/008 , A61M25/0082
摘要： Devices and methods for removing an obstruction from a blood vessel are described. The devices are deployed in a collapsed condition and are then expanded within the body. The devices are then manipulated to engage and remove the obstruction.

33. 发明申请

US20060116712A1 Aneurysm treatment devices and methods 失效
标题翻译：动脉瘤治疗装置及方法
公开(公告)号：US20060116712A1
公开(公告)日：2006-06-01
申请号：US11111487
申请日：2005-04-21
申请人： Ivan Sepetka , Maria Aboytes , Maybelle Jordan , Craig Friedman , Arindam Datta
发明人： Ivan Sepetka , Maria Aboytes , Maybelle Jordan , Craig Friedman , Arindam Datta
IPC分类号： A61M29/00
CPC分类号： A61B17/12022 , A61B17/12113 , A61B17/12145 , A61B17/1215 , A61B17/12163 , A61B17/12172 , A61B17/12181 , A61B90/39 , A61B2017/00862 , A61B2017/00867 , A61B2017/1205 , A61B2017/12054 , A61B2017/12095
摘要： An aneurysm treatment device for in situ treatment of aneurysms comprises a collapsible member having a first shape wherein the first shape is an expanded geometric configuration, and a second shape, wherein the second shape is a collapsed configuration that is loadable into a catheter. The aneurysm treatment device is capable or returning to the first shape in the sac of an aneurysm upon deployment, where it occludes the aneurysm. In another embodiment an occlusion device comprises a flexible, longitudinally extending elastomeric matrix member that assumes a non-linear shape to conformally fill a targeted vascular site.
摘要翻译：用于动态瘤的原位治疗的动脉瘤治疗装置包括具有第一形状的可折叠构件，其中第一形状是扩张几何形状，以及第二形状，其中第二形状是可装载到导管中的收缩构型。动脉瘤治疗装置在部署时能够或返回到动脉瘤囊中的第一形状，其中阻塞动脉瘤。在另一个实施例中，闭塞装置包括柔性的纵向延伸的弹性体基体构件，其构成保形填充目标血管部位的非线性形状。

34. 发明申请

US20050059995A1 Systems, methods and devices for removing obstructions from a blood vessel 有权
公开(公告)号：US20050059995A1
公开(公告)日：2005-03-17
申请号：US10973888
申请日：2004-10-25
申请人： Ivan Sepetka , Son Gia , John Miller , Ryan Pierce , Maria Aboytes , Tiffany Ngo
发明人： Ivan Sepetka , Son Gia , John Miller , Ryan Pierce , Maria Aboytes , Tiffany Ngo
IPC分类号： A61B17/22 , A61B17/24 , A61M1/00 , A61M29/00
CPC分类号： A61B17/3207 , A61B17/22031 , A61B17/221 , A61B17/320725 , A61B18/1492 , A61B2017/22034 , A61B2017/2217 , A61B2017/320716 , A61B2018/00214 , A61B2018/00898
摘要： Devices and methods for removing an obstruction from a blood vessel are described. The devices are deployed in a collapsed condition and are then expanded within the body. The devices are then manipulated to engage and remove the obstruction.

35. 发明授权

US06663650B2 Systems, methods and devices for removing obstructions from a blood vessel 有权
公开(公告)号：US06663650B2
公开(公告)日：2003-12-16
申请号：US09756476
申请日：2001-01-08
申请人： Ivan Sepetka , Martin Dieck , Son Gia
发明人： Ivan Sepetka , Martin Dieck , Son Gia
IPC分类号： A61M2900
CPC分类号： A61B17/22031 , A61B17/221 , A61B18/1492 , A61B2017/22034 , A61B2017/2212 , A61B2017/2215 , A61B2017/2217 , A61B2018/00214 , A61B2018/00898 , A61F2/013 , A61F2002/016 , A61F2002/018 , A61F2230/0067 , A61F2230/0091 , A61M25/0068 , A61M25/0074 , A61M25/008 , A61M25/0082
摘要： A system for removing an obstruction from a blood vessel includes an obstruction engaging element and an expandable capture element. The capture element preferably has a flexible cover and an expandable support structure. The engaging element engages the obstruction and moves the obstruction into the capture element. The capture element protects the obstruction when the obstruction is moved into the catheter.

36. 发明授权

US06494884B2 Methods and devices for delivering occlusion elements 有权
公开(公告)号：US06494884B2
公开(公告)日：2002-12-17
申请号：US09780587
申请日：2001-02-09
申请人： Hanson S. Gifford, III , Ivan Sepetka , Son Gia , Maria Aboytes
发明人： Hanson S. Gifford, III , Ivan Sepetka , Son Gia , Maria Aboytes
IPC分类号： A61B1700
CPC分类号： A61B17/1214 , A61B17/12022 , A61B17/12145 , A61B17/1215 , A61B2017/00477 , A61B2017/12059 , A61M25/007
摘要： A device for delivering an occlusion element, or other medical device, which includes a fluid dissolvable bond. The occlusion element is coupled to the delivery element with the fluid dissolvable bond. The bond may be dissolved by delivering a fluid through the delivery element either through the delivery element itself or through a tube positioned in the delivery element.

37. 发明授权

US6123714A System for detaching an occlusive device within a body using a solderless, electrolytically severable joint 失效
公开(公告)号：US6123714A
公开(公告)日：2000-09-26
申请号：US743494
申请日：1996-11-04
申请人： Son Gia , Hong Doan , Pete Phong Pham , Ivan Sepetka , U. Hiram Chee , Michael Mariant , David Kupiecki
发明人： Son Gia , Hong Doan , Pete Phong Pham , Ivan Sepetka , U. Hiram Chee , Michael Mariant , David Kupiecki
IPC分类号： A61F2/82 , A61B17/00 , A61B17/12 , A61F2/06 , A61F2/84 , A61B17/08
CPC分类号： A61B17/12022 , A61B17/12113 , A61B17/12145 , A61F2/95 , A61B2017/00017 , A61B2017/00292 , A61B2017/12063 , A61B2018/1495
摘要： A solderless sacrificial link between a detachable member which is placed at and is intended to remain at a desired site within the mammalian body and the core wire used to introduce the detachable member. The detachable member device may be one used to create emboli in the vascular system or may be of any other type deliverable into the human body and detached into an ionic aqueous environment, either for later removal or permanent placement.

38. 发明授权

US6019771A Devices and methods for minimally invasive harvesting of a vessel especially the saphenous vein for coronary bypass grafting 失效
标题翻译：用于微创收集血管的装置和方法，特别是用于冠状动脉搭桥术的隐静脉
公开(公告)号：US6019771A
公开(公告)日：2000-02-01
申请号：US759102
申请日：1996-12-02
申请人： Brian J. Bennett , Dwight P. Morejohn , Ivan Sepetka
发明人： Brian J. Bennett , Dwight P. Morejohn , Ivan Sepetka
IPC分类号： A61B17/00 , A61B17/128 , A61B17/32
CPC分类号： A61B17/00008 , A61B17/32002 , A61B17/1285 , A61B17/3201
摘要： Devices and methods for minimally invasive harvesting of a vessel, especially the saphenous vein for coronary artery bypass grafting, are disclosed which facilitate a minimally invasive vessel harvesting procedure. Generally, an instrument is provided which facilitates introduction of vessel harvesting tools through a minimally invasive incision, and provides the capability to separate the vessel from surrounding tissue while minimizing trauma to the patient and preserving the patency of the vessel. The instrument includes a mechanism for separating the vessel from surrounding tissue and may also include mechanisms for severing side branches from the vessel during the harvesting procedure. In one embodiment, an integrated vessel harvesting assembly is provided which may rotate around a vessel and provides a unitary mechanism for separating the vessel from surrounding tissue and for severing the side branches.
摘要翻译：公开了用于微创收集血管，尤其是用于冠状动脉旁路移植术的隐静脉的装置和方法，其有助于微创血管收获程序。通常，提供了便于通过微创切口引入血管收集工具的仪器，并且提供了将血管与周围组织分开同时最小化对患者的创伤并保持血管通畅性的能力。该仪器包括用于将容器与周围组织分开的机构，并且还可包括用于在收获过程期间切断侧分支的装置。在一个实施例中，提供集成的血管收集组件，其可围绕血管旋转并且提供用于将血管与周围组织分离并用于切断侧枝的整体机构。

39. 发明授权

US6001111A Low profile vessel occluder with and without detachable applicator 失效
标题翻译：具有和不具有可拆卸涂抹器的低轮廓血管封堵器
公开(公告)号：US6001111A
公开(公告)日：1999-12-14
申请号：US8113
申请日：1998-01-16
申请人： Ivan Sepetka , Robert G. Matheny , James A. Magovern , Dwight P. Morejohn , Robert C. Glines
发明人： Ivan Sepetka , Robert G. Matheny , James A. Magovern , Dwight P. Morejohn , Robert C. Glines
IPC分类号： A61B17/04 , A61B17/06 , A61B17/064 , A61B17/122 , A61B17/128 , A61B17/00
CPC分类号： A61B17/122 , A61B17/0487 , A61B17/06 , A61B17/0643 , A61B17/128 , A61B2017/0461 , A61B2017/0464
摘要： A low profile unobtrusive occluder device is disclosed which is particularly applicable for occluding blood vessels in minimally invasive beating heart CABG surgical procedures, wherein relatively small surgical openings are provided. At least one flexible member is provided on the occluder, which is placed against the vessel. A suture thread is passed under the vessel to encompass the vessel between the occluder and suture thread. The suture thread is selectively attached to the occluder such that the flexible member, when deformed, applies continuous selected tension on the suture thread to apply a corresponding compression on the vessel which occludes the flow of blood. An applicator is attached to the occluder to enable installation thereof, but is detachable after installation such that only the low profile occluder remains on the heart surface during surgery. The applicator is re-attached to the occluder to facilitate removal of the latter. In an alternative embodiment, the occluder is formed as an adjustable part of a heart contacting member of a thoracotomy stabilizer apparatus.
摘要翻译：公开了一种低调的不引人注意的闭塞器装置，其特别适用于在微创搏动心脏CABG外科手术中闭塞血管，其中提供了相对较小的手术开口。至少一个柔性构件设置在封闭器上，其抵靠容器放置。缝合线在血管下方通过封闭器和缝合线之间的容器。缝合线选择性地附接到闭塞器，使得当变形时，柔性构件在缝合线上施加连续的选定张力，以在封闭血流的血管上施加相应的压缩。敷贴器附接到封堵器以使其能够安装，但是在安装之后可拆卸，使得在外科手术期间只有低轮廓的封堵器保留在心脏表面上。将施用器重新连接到封堵器以便于去除封堵器。在替代实施例中，封堵器形成为开胸稳定器装置的心脏接触构件的可调部分。

40. 发明授权

US5766160A Variable stiffness coils 失效
标题翻译：可变刚度线圈
公开(公告)号：US5766160A
公开(公告)日：1998-06-16
申请号：US480042
申请日：1995-06-06
申请人： Gene Samson , Ivan Sepetka , U. Hiram Chee , Christopher G. M. Ken , Nga T. Van
发明人： Gene Samson , Ivan Sepetka , U. Hiram Chee , Christopher G. M. Ken , Nga T. Van
IPC分类号： A61M31/00 , A61B17/12 , A61B17/00
CPC分类号： A61B17/1215 , A61B17/12022 , A61B17/12109 , A61B17/12145
摘要： This invention is an implantable vaso-occlusive device. It is a helically wound coil having a central section along its longitudinal axis which is somewhat stiffer than at least one of its end regions.
摘要翻译：本发明是可植入血管闭塞装置。它是螺旋缠绕的线圈，其沿其纵向轴线具有中心部分，该中心部分比其端部区域中的至少一个稍微更硬。

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