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31. 发明申请

WO2011065677A3 PHARMACEUTICAL COMPOSITION FOR TREATING CANCER 审中-公开
标题翻译：治疗癌症的药物组合物
公开(公告)号：WO2011065677A3
公开(公告)日：2011-11-03
申请号：PCT/KR2010007600
申请日：2010-11-01
申请人： KOREA RES INST OF BIOSCIENCE , WON MISUN , CHUNG KYUNG-SOOK , KIM YOUNG JOO , HONG HYE KYUNG , YEOM YOUNG IL , YUN CHAE OK , OH YU KYUNG , SONG KYUNG BIN , LEE HEE GU , SONG EUN YOUNG , KIM YOUNG HO , KIM MOON HEE , JUNG KYEONG-EUN
发明人： WON MISUN , CHUNG KYUNG-SOOK , KIM YOUNG JOO , HONG HYE KYUNG , YEOM YOUNG IL , YUN CHAE OK , OH YU KYUNG , SONG KYUNG BIN , LEE HEE GU , SONG EUN YOUNG , KIM YOUNG HO , KIM MOON HEE , JUNG KYEONG-EUN
IPC分类号： A61K31/7105 , A61K31/711 , A61P35/00
CPC分类号： C12N15/113 , A61K31/7105 , A61K31/711 , A61K31/713 , C12N2310/531
摘要： The present invention provides a pharmaceutical composition for treating cancer, comprising at least one selected from deoxyribonucleic acids (DNA) for encoding small interfering RNA (siRNA) which complementarily binds to the base sequence of the transcript (mRNA transcript) of the FLJ25416 gene, represented by sequence number 3, sequence number 5, and sequence number 7 to inhibit the intracellular expression of the FLJ25416 gene, antisense RNA which inhibits expression of the FLJ25416 gene, and short hairpin RNA (shRNA) which inhibits expression of the FLJ25416 gene. As the siRNA, which is complementary to the base sequence of the transcript (mRNA transcript) of the FLJ25416 gene, the antisense RNA, and the shRNA, according to the present invention, inhibit expression of the FLJ25416 gene which is known to be expressed in cancer cells, and thus kill cancer cells, the composition of the present invention can be used as a novel anti-cancer agent.
摘要翻译：本发明提供用于治疗癌症的药物组合物，其包含选自用于编码与FLJ25416基因的转录物（mRNA转录物）的碱基序列互补结合的小干扰RNA（siRNA）的脱氧核糖核酸（DNA）中的至少一种，序列号3，序列号5和序列号7以抑制FLJ25416基因的细胞内表达，抑制FLJ25416基因表达的反义RNA和抑制FLJ25416基因表达的短发夹RNA（shRNA）。由于本发明的与FLJ25416基因，反义RNA和shRNA的转录物（mRNA转录物）的碱基序列互补的siRNA抑制已知表达癌细胞，从而杀死癌细胞，本发明的组合物可以用作新型的抗癌剂。

32. 发明申请

WO2010110616A3 DUAL MASS FLYWHEEL 审中-公开
标题翻译：双质量飞轮
公开(公告)号：WO2010110616A3
公开(公告)日：2010-12-23
申请号：PCT/KR2010001854
申请日：2010-03-26
申请人： SEOJIN CLUTCH CO LTD , KIM YOUNG HO
发明人： KIM YOUNG HO
IPC分类号： F16F15/30 , F16F15/31
CPC分类号： F16F15/13438
摘要： The present invention relates to a dual mass flywheel for power transmission, and more particularly, to a dual mass flywheel which suppresses noise and vibrations during the operation thereof. The present invention provides a dual mass flywheel comprising: a primary mass to which driving force is transmitted from a driving unit; a cover plate coupled to the primary mass; a driving plate which rotates by means of the cover plate; a secondary mass coupled to the driving plate to transmit rotating force to a slave unit; a buffering member interposed between the cover plate and the driving plate; and a fixing unit for suppressing the movement of the buffering member.
摘要翻译：双质量飞轮技术领域本发明涉及一种用于动力传输的双质量飞轮，并且更具体地涉及一种抑制在其操作期间的噪声和振动的双质量飞轮。本发明提供一种双质量飞轮，其包括：从驱动单元向其传输驱动力的主质量块; 联接到主质量块的盖板; 借助于盖板旋转的驱动板; 辅助质量，其耦合到所述驱动板以将旋转力传输到从属单元; 插入盖板和驱动板之间的缓冲构件; 以及用于抑制缓冲构件的移动的固定单元。

33. 发明申请

WO2009072831A3 NOVEL USE OF FLJ25416 GENE 审中-公开
标题翻译： FLJ25416基因的新用途
公开(公告)号：WO2009072831A3
公开(公告)日：2009-08-20
申请号：PCT/KR2008007196
申请日：2008-12-05
申请人： KOREA RES INST OF BIOSCIENCE , SAMCHULLY PHARM CO LTD , WON MISUN , CHUNG KYUNG-SOOK , KIM YOUNG-JOO , CHOI SHIN-JUNG , YEOM YOUNG IL , KIM SEON-YOUNG , SONG KYUNG BIN , LEE HEE GU , SONG EUN YOUNG , KIM YOUNG HO , CHUN HO KYUNG , YUN CHAE-OK , KIM MOON HEE , JUNG KYEONG-EUN , CHO SUN-JUNG
发明人： WON MISUN , CHUNG KYUNG-SOOK , KIM YOUNG-JOO , CHOI SHIN-JUNG , YEOM YOUNG IL , KIM SEON-YOUNG , SONG KYUNG BIN , LEE HEE GU , SONG EUN YOUNG , KIM YOUNG HO , CHUN HO KYUNG , YUN CHAE-OK , KIM MOON HEE , JUNG KYEONG-EUN , CHO SUN-JUNG
IPC分类号： A61K38/17 , A61P35/00
CPC分类号： G01N33/57484 , A61K31/7088 , A61K38/1709 , C12N15/1135 , C12N15/86 , C12N2310/111 , C12N2310/14 , C12N2710/10343 , C12Q1/6886 , C12Q2600/136 , C12Q2600/158 , G01N2500/00 , G01N2500/04
摘要： Provided are a composition for diagnosing cancer or screening an anticancer drug comprising an FLJ25416 gene or an antibody directed to a protein expressed from the FLJ25416 gene, a composition for treating cancer comprising an inhibitor of the gene or an inhibitor of the protein expressed from the gene and a pharmaceutically acceptable carrier, and a kit for diagnosing cancer comprising at least one of the FLJ25416 gene and the protein expressed from the FLJ25416 gene. The FLJ25416 gene is expressed at high level in specific cancer cells, and induces an increase in proliferation rate of normal cells. The expression of the gene is suppressed, which results in an inhibitory effect on cancer cell growth. Thus, the FLJ25416 gene can be used as a target gene for diagnosis or treatment of cancer.
摘要翻译：本发明提供了用于诊断癌症或筛选包含FLJ25416基因或针对由FLJ25416基因表达的蛋白质的抗体的抗癌药物的组合物，用于治疗癌症的组合物，所述组合物包含所述基因的抑制剂或由所述基因表达的蛋白质的抑制剂和药学上可接受的载体以及用于诊断癌症的试剂盒，其包含FLJ25416基因和由FLJ25416基因表达的蛋白质中的至少一种。 FLJ25416基因在特定癌细胞中高水平表达，并诱导正常细胞增殖速率增加。该基因的表达被抑制，这导致对癌细胞生长的抑制作用。因此，FLJ25416基因可以用作诊断或治疗癌症的靶基因。

34. 发明申请

WO2013055131A2 NOSE MASK 审中-公开
公开(公告)号：WO2013055131A2
公开(公告)日：2013-04-18
申请号：PCT/KR2012008277
申请日：2012-10-11
申请人： KIM YOUNG HO , KIM HYUN JEONG
发明人： KIM YOUNG HO , KIM HYUN JEONG
IPC分类号： A62B23/06 , A62B7/10 , A62B18/02
CPC分类号： A41D13/1115 , A62B23/025 , A62B23/06
摘要： The present invention relates to a nose mask which can also be used as a face mask, wherein it is possible to freely speak since the mask does not cover the mouth, a filtering area can be enlarged by forming a pocket-type structure by a main body and an inner filter, and it is possible to effectively fill up the gap under the nose and the gap under the eyes by closely adhering the inner filter. Further, the mask is folded flat before being worn, and automatically displays a force extending a high and wide space and a force maintaining a firm shape by a wrinkle complex formed horizontally and vertically at the main body and the inner filter when being worn, thereby enabling easy breathing.

35. 发明申请

WO2012138203A3 ACTIVE ROBOTIC GAIT-TRAINING SYSTEM AND METHOD 审中-公开
标题翻译：主动机器人训练系统及方法
公开(公告)号：WO2012138203A3
公开(公告)日：2013-01-17
申请号：PCT/KR2012002678
申请日：2012-04-09
申请人： UNIV YONSEI IACF , KIM YOUNG HO , HWANG SUNG JAE , SON JONG SANG , KIM JUNG YOON , PARK SUN WOO , RYU JE SEONG , LEE MIN HYEON
发明人： KIM YOUNG HO , HWANG SUNG JAE , SON JONG SANG , KIM JUNG YOON , PARK SUN WOO , RYU JE SEONG , LEE MIN HYEON
IPC分类号： A61H1/02 , A61H3/00 , A61N1/36 , B25J13/08
CPC分类号： A61H1/0255 , A61H1/0262 , A61H2201/10 , A61H2201/163 , A61H2201/1642 , A61H2201/5069 , A61N1/36003 , A61N1/36014 , A63B21/00178 , A63B21/00181 , A63B21/4009 , A63B21/4011 , A63B22/0235 , A63B69/0064 , A63B71/0009 , A63B2022/0094 , A63B2213/004 , A63B2220/16
摘要： The present invention relates to an active robotic gait-training system and method, which involve measuring the tilt of a lower leg to estimate a gait cycle and enable a hip joint and a knee joint to operate by means of an actuator in accordance with the gait cycle, and which enable an ankle joint to operate by functional electrical stimulation (FES), thus enabling more active gait training for a person with dysbasia in accordance with the remaining walking ability of the person with dysbasia. According to the present invention, a robot-assisted gait-training system, including a thigh support unit, a hip joint support unit and a lower leg support unit, comprises: a toe-fixing ring which is arranged at the lower end of the lower leg support unit and to which a string, which is connected to a foot strap for covering a foot (tiptoe) part, is fixed; a tilt sensor attached to the lower end of the lower leg support unit or to one side of the foot strap; a control unit which generates an FES control signal, a hip joint angle control signal, and a knee joint angle control signal from the tilt signal received from the tilt sensor; a first linear actuator which receives the hip joint angle control signal from the control unit, and rotates the thigh support unit at a hip joint unit, which is a coupling unit between the thigh support unit and the hip joint support unit, in accordance with the hip joint angle control signal; and a second linear actuator which receives the knee joint angle control signal from the control unit, and rotates the lower leg support unit at a knee joint unit, which is a coupling unit between the lower leg support unit and the thigh support unit, in accordance with the knee joint angle control signal.
摘要翻译：本发明涉及一种主动机器人步态训练系统和方法，其涉及测量小腿的倾斜以估计步态循环，并且使得髋关节和膝关节能够根据步态通过致动器进行操作循环，并且其使踝关节能够通过功能性电刺激（FES）进行操作，从而根据失聪者的剩余行走能力，使得对于具有失语症的人进行更积极的步态训练。根据本发明，一种机器人辅助步态训练系统，包括大腿支撑单元，髋关节支撑单元和小腿支撑单元，包括：脚趾固定环，其布置在下部的下端腿部支撑单元，并且连接到用于覆盖脚（脚尖）部分的脚带的绳索被固定; 倾斜传感器，其附接到小腿支撑单元的下端或者脚带的一侧; 控制单元，其根据从倾斜传感器接收的倾斜信号生成FES控制信号，髋关节角度控制信号和膝关节角度控制信号; 第一线性致动器，其接收来自控制单元的髋关节角度控制信号，并且在大腿支撑单元和髋关节支撑单元之间的联接单元的髋关节单元处，按照髋关节角度控制信号; 以及第二线性致动器，其从所述控制单元接收所述膝关节角度控制信号，并且在所述小腿支撑单元和所述大腿支撑单元之间的联接单元的膝关节单元处，将所述小腿支撑单元旋转，与膝关节角度控制信号。

36. 发明申请

WO2012070907A3 STRUCTURE FOR COUPLING TOGETHER A FRAME AND A SIDEPIECE OF EYEGLASSES 审中-公开
标题翻译：用于连接框架和眼罩的SIDEEPIECE的结构
公开(公告)号：WO2012070907A3
公开(公告)日：2012-09-27
申请号：PCT/KR2011009062
申请日：2011-11-25
申请人： KIM YOUNG HO
发明人： KIM YOUNG HO
IPC分类号： G02C5/22 , G02C1/06 , G02C5/14
CPC分类号： G02C5/2254 , G02C1/08 , G02C5/2209 , G02C2200/06 , G02C2200/12 , G02C2200/22 , Y10T16/526
摘要： The present invention relates to a structure for coupling together a frame and a sidepiece of eyeglasses, and more particularly, to a structure for coupling together a frame and a sidepiece of eyeglasses, in which the frame and the sidepiece can be easily coupled or uncoupled to/from each other, which enables a lens to be easily coupled to the frame, and which provides elasticity when the sidepiece is folded or unfolded. The coupling structure of the present invention comprises: a hinge piece (2) tightly inserted between end pieces (E) split at a distal end of the frame such that the hinge piece (2) protrudes, wherein the hinge piece (2) has a stopper groove (1); an elastic member (4) having a slot (3) for the insertion of the hinge piece (2); and a sidepiece (T) having a rotation pin (8) and an operating slot (5) such that a front end of the sidepiece (T) can be fitted into the stopper groove (1) while elastically pressing the elastic member (4). Alternatively, the coupling structure of the present invention comprises: a hinge piece (2) protruding from the inside of an end piece (E) integrally formed with an end of the frame by synthetic-resin injection-molding, wherein the hinge piece (2) has a stopper groove (1); an elastic member (4) having an upper plate and a lower plate, wherein an intermediate portion of the upper plate is elastically bent, the upper plate and the lower plate have respective slots (3) to be doubly fitted onto the hinge piece (2), and the intermediate portion of the upper plate is bent at a predetermined angle to form a protrusion (6) in the horizontal direction; and a sidepiece (T), the front end of which has a rotation pin (8) such that the front end of the sidepiece (T) can be fitted into the stopper groove (1) of the hinge piece (2) while elastically pressing the upper plate of the elastic member (4), wherein the sidepiece (T) has a relatively vertically elongate operating slot (5) at the front end thereof such that the sidepiece (T) is rotatable about the rotation pin (8).
摘要翻译：本发明涉及一种用于将眼镜的镜架和镜架连接在一起的结构，更具体地说，涉及一种用于将眼镜的镜架和镜架连接在一起的结构，其中框架和镜架可以容易地连接或脱开 /彼此接合，这使得镜片能够容易地联接到框架，并且在侧边件折叠或展开时提供弹性。本发明的连接结构包括：紧固地插入在框架的远端处分开的端部件（E）之间的铰接件（2），使得铰接件（2）突出，其中铰接件（2）具有止动槽（1）; 一个具有用于插入铰链件（2）的槽（3）的弹性件（4）; 和具有旋转销（8）和操作槽（5）的侧边件（T），使得在弹性地按压弹性构件（4）的同时，侧边件（T）的前端能够配合到止动槽（1）。或者，本发明的连接结构包括：通过合成树脂注塑成型从与框架的端部一体形成的端部件（E）的内部突出的铰链件（2），其中铰链件（2 ）具有止动槽（1）; 具有上板和下板的弹性构件（4），其中上板的中间部分被弹性弯曲，上板和下板具有各自的槽（3）以双重地装配到铰链件（2 ），并且上板的中间部分以预定角度弯曲以在水平方向上形成突起（6）（T），其前端具有旋转销（8），使得侧边件（T）的前端能够在弹性加压的同时装配到铰链件（2）的止动槽（1）中（4）的上板，其中，所述侧部件（T）在其前端处具有相对垂直伸长的操作槽（5），使得所述侧部件（T）能够围绕所述旋转销（8）旋转。

37. 发明申请

WO2011132936A3 STRUCTURE FOR CONNECTING TEMPLE TO EYEGLASS FRAME 审中-公开
标题翻译：将样品连接到眼镜框架的结构
公开(公告)号：WO2011132936A3
公开(公告)日：2012-03-08
申请号：PCT/KR2011002834
申请日：2011-04-20
申请人： KIM YOUNG HO
发明人： KIM YOUNG HO
IPC分类号： G02C5/22 , G02C5/14 , G02C13/00
CPC分类号： G02C1/06 , G02C5/2209 , G02C5/2254 , G02C2200/04 , G02C2200/06 , G02C2200/12 , G02C2200/22
摘要： The present invention relates to a structure for connecting a temple to an eyeglass frame and, more specifically, to a temple connecting structure for eyeglass frames which allows the temple to be folded with a hinge, for temples and eyeglass frames made of titanium, especially beta-titanium, which is light weight and has high hardness and traction force. An object of the present invention is to provide a temple connecting structure for eyeglass frames, which comprises a plate made of a beta-titanium material having high traction force for folding the temple instead of using a feldspar that is usually welded and fixed to the temple and the frame, which prevents the temple or the frame from being prone to wear even after repetitive folding and unfolding motions of the temple, and which enables the temple to be folded or unfolded at a preset angle to facilitate the folding motion of the temple. To realize this object, the present invention is comprised of a frame (1) made of a beta-titanium-based plate, the frame being connected to lenses (L); a temple (2) made of a beta-titanium-based plate; and a rotational means disposed between the temple (2) and the frame (1) to enable the temple (2) to elastically rotate and be foldable.
摘要翻译：本发明涉及一种用于将镜腿连接到眼镜框架的结构，更具体地，涉及一种用于眼镜架的镜腿连接结构，其允许镜腿用铰链折叠，用于由钛制造的镜腿和眼镜框，特别是β 钛，重量轻，硬度高，牵引力强。本发明的目的是提供一种用于眼镜架的镜腿连接结构，其包括由具有高牵引力的β钛材料制成的板，用于折叠镜腿，而不是使用通常焊接并固定到镜腿的长石以及框架，即使在镜腿的重复折叠和展开运动之后也能够使镜腿或框架容易磨损，并且能够以预设的角度折叠或展开镜腿，以促进镜腿的折叠运动。为了实现该目的，本发明包括由β钛基板制成的框架（1），该框架连接到透镜（L）; 由β钛基板制成的寺庙（2）; 以及设置在镜腿（2）和镜架（1）之间的旋转装置，以使镜腿（2）能够弹性旋转并且可折叠。

38. 发明申请

WO2010120077A3 WINDOW BLIND APPARATUS IN WHICH A DOUBLE BLIND SHEET IS CAPABLE OF BEING OPENED/SHUT DURING UPWARD/DOWNWARD MOVEMENT 审中-公开
标题翻译：双面玻璃装置可以在上/下移动期间打开/关闭双面布板
公开(公告)号：WO2010120077A3
公开(公告)日：2011-03-24
申请号：PCT/KR2010002243
申请日：2010-04-12
申请人： JUWONCHANGHO CO LTD , KIM YOUNG HO
发明人： KIM YOUNG HO
IPC分类号： E06B9/42 , E06B9/56
CPC分类号： E06B9/34 , E06B2009/2435
摘要： The present invention provides a window blind apparatus comprising: a double blind sheet; a winding rod for winding the double blind sheet thereon; a guide rod for guiding the double blind sheet; a driving control unit for driving the winding rod and the guide rod; a housing; and a sheet-opening unit arranged in the housing to open the double blind sheet. The window blind apparatus moves the guide rod to adjust the opening/shutting of the blind sheet during the upward/downward movement of the blind sheet.
摘要翻译：本发明提供一种窗帘设备，包括：双盲片; 用于将双盲片卷绕在其上的卷绕杆; 用于引导双盲片的导杆; 用于驱动所述卷绕杆和所述导杆的驱动控制单元; 房屋; 以及布置在所述壳体中以打开所述双盲片的片材打开单元。窗帘设备移动导杆，以在遮板的向上/向下运动期间调节遮板的打开/关闭。

39. 发明申请

WO2010067969A3 NOVEL USE OF THE LOC284422 GENE 审中-公开
标题翻译： LOC284422基因的新用途
公开(公告)号：WO2010067969A3
公开(公告)日：2010-09-23
申请号：PCT/KR2009006832
申请日：2009-11-19
申请人： KOREA RES INST OF BIOSCIENCE , WON MISUN , CHUNG KYUNG-SOOK , CHO SUN-JUNG , CHOI SHIN-JUNG , YEOM YOUNG IL , KIM SEON-YOUNG , SONG KYUNG BIN , LEE HEE GU , SONG EUN YOUNG , KIM YOUNG HO , CHUN HO KYUNG , KIM MOON HEE , JUNG KYEONG-EUN , OH YU-KYOUNG
发明人： WON MISUN , CHUNG KYUNG-SOOK , CHO SUN-JUNG , CHOI SHIN-JUNG , YEOM YOUNG IL , KIM SEON-YOUNG , SONG KYUNG BIN , LEE HEE GU , SONG EUN YOUNG , KIM YOUNG HO , CHUN HO KYUNG , KIM MOON HEE , JUNG KYEONG-EUN , OH YU-KYOUNG
IPC分类号： C12N15/12 , C12N15/10 , C12Q1/68 , G01N33/574
CPC分类号： C07K14/4748 , C12N15/113 , C12N2310/14 , C12Q1/6886 , C12Q2600/136 , G01N33/57484 , G01N2500/00
摘要： The present invention provides a composition for cancer diagnosis or anti-cancer drug screening containing the LOC284422 gene or an antibody against the proteins expressed by LOC284422 gene, to a cancer treatment composition containing an inhibitor for said gene, an inhibitor for the proteins expressed by said gene, and a pharmaceutically acceptable carrier, and to a kit for cancer diagnosis containing the LOC284422 gene or one or more of the proteins expressed by the LOC284422 gene. The LOC284422 gene of the present invention is largely expressed in cancer cells, and increases the growth speed of normal cells. Therefore, the inhibition of the expression of this gene leads to the inhibition of the growth of cancer cells. Accordingly, the LOC284422 gene can be used as a target gene for the diagnosis of therapeutic agents for different types of cancer.
摘要翻译：本发明提供了含有LOC284422基因或针对由LOC284422基因表达的蛋白质的抗体的癌症诊断或抗癌药物筛选的组合物，其含有所述基因的抑制剂的癌症治疗组合物，所述蛋白质表达的蛋白质抑制剂基因和药学上可接受的载体，以及含有LOC284422基因或LOC284422基因表达的一种或多种蛋白质的癌症诊断试剂盒。本发明的LOC284422基因在癌细胞中大量表达，并且增加正常细胞的生长速度。因此，抑制该基因的表达导致癌细胞生长的抑制。因此，LOC284422基因可用作诊断不同类型癌症治疗剂的靶基因。

40. 发明申请

WO2009131366A3 CDCA5 AS A DIAGNOSIS MARKER AND THERAPEUTIC AGENT FOR GASTRIC CANCER OR COLORECTAL CANCER 审中-公开
标题翻译： CDCA5作为胃癌或色素沉着病的诊断标记和治疗药物
公开(公告)号：WO2009131366A3
公开(公告)日：2010-01-21
申请号：PCT/KR2009002085
申请日：2009-04-21
申请人： KOREA RES INST OF BIOSCIENCE , YEOM YOUNG IL , LEE HEE GU , YOON HYO RAN , KIM JAE WHA , SONG EUN YOUNG , KIM JONG TAE , KIM YOUNG HO , CHUN HO KYUNG , CHUNG KYUNG-SOOK , WON MISUN
发明人： YEOM YOUNG IL , LEE HEE GU , YOON HYO RAN , KIM JAE WHA , SONG EUN YOUNG , KIM JONG TAE , KIM YOUNG HO , CHUN HO KYUNG , CHUNG KYUNG-SOOK , WON MISUN
IPC分类号： C12Q1/68
CPC分类号： C12Q1/6886 , C12Q2600/106 , C12Q2600/136 , C12Q2600/158 , C12Q2600/178
摘要： The present invention relates to bio marker CDCA5 (cell division cycle associated 5) which is specific to gastric cancer or colorectal cancer. More specifically, this invention concerns a composition for diagnosing gastric cancer or colorectal cancer which contains an agent measuring the expression level of CDCA 5, a kit containing the composition, a method for detecting the marker, and a method for screening a therapeutic agent of gastric cancer or colorectal cancer using the marker. In addition, this invention relates to a pharmaceutical composition for preventing and treating cancer, which contains a material inhibiting the expression or activation of CDCA5.
摘要翻译：本发明涉及对胃癌或结肠直肠癌特异性的生物标志物CDCA5（细胞分裂周期相关的5）。更具体地，本发明涉及用于诊断胃癌或结肠直肠癌的组合物，其包含测量CDCA 5的表达水平的试剂，含有该组合物的试剂盒，用于检测标记物的方法，以及筛选胃癌治疗剂的方法使用标记的癌症或结肠直肠癌。此外，本发明涉及用于预防和治疗癌症的药物组合物，其含有抑制CDCA5表达或活化的材料。

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