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31. 发明授权

US06397850B1 Dual-mode apparatus and method for detection of embolic device detachment 有权
标题翻译：用于检测栓塞装置脱离的双模式装置和方法
公开(公告)号：US06397850B1
公开(公告)日：2002-06-04
申请号：US09501340
申请日：2000-02-09
申请人： Ronald W. Scheldrup , Jason E. Kalgreen , Mehran Bashiri
发明人： Ronald W. Scheldrup , Jason E. Kalgreen , Mehran Bashiri
IPC分类号： A61M2900
CPC分类号： A61B17/12022 , A61B17/12113 , A61B17/12145 , A61B2017/00022 , A61B2017/00026 , A61B2017/12063
摘要： An apparatus and method are disclosed for accurately detecting the detachment of both electrically conductive and non-conductive implants which have been introduced to and are intended to remain at a desired therapeutic site. The detachment detection apparatus may include a conductive or an electrically-isolated implant, such as a vasoocclusive coil, connected to a wire by an electrolytically severable joint. The detachment assembly further includes a power supply having a direct current drive circuit for supplying a direct current to the joint, an alternating current drive circuit for independently supplying an alternating current to the joint, and an alternating current monitoring circuit for monitoring an alternating current level of the alternating current supplied to the joint. The detection assembly includes a central processing unit for selecting a first mode and a second mode for determining a detachment threshold level indicating detachment of the implant. Additionally, a direct current monitoring circuit is provided for measuring a direct current impedance level of the direct current supplied to the joint wherein a percentage increase in the direct current impedance level indicates detachment of the implant if the alternating current level is greater than the detachment threshold level.
摘要翻译：公开了一种用于精确地检测导入和预期保留在期望的治疗部位的导电植入物和非导电植入物的脱离的装置和方法。分离检测装置可以包括导电或电隔离的植入物，例如血管闭塞线圈，其通过电解可分离的关节连接到线。分离组件还包括具有用于向接头提供直流电流的直流驱动电路的电源，用于向接头独立提供交流电的交流驱动电路，以及用于监控交流电平的交流监视电路提供给接头的交流电。检测组件包括用于选择第一模式的中央处理单元和用于确定指示植入物脱离的脱离阈值水平的第二模式。此外，提供直流监测电路用于测量提供给接头的直流电流的直流阻抗水平，其中如果交流电流大于分离阈值，则直流阻抗水平的百分比增加指示植入物的分离水平。

32. 发明授权

US06344041B1 Aneurysm closure device assembly 有权
标题翻译：动脉瘤闭合装置组装
公开(公告)号：US06344041B1
公开(公告)日：2002-02-05
申请号：US09699267
申请日：2001-10-26
申请人： David Kupiecki , Clifford Teoh , Hong Doan , Son M. Gia , Erik T. Engelson , Uriel Hiram Chee , Mehran Bashiri , Joseph C. Eder
发明人： David Kupiecki , Clifford Teoh , Hong Doan , Son M. Gia , Erik T. Engelson , Uriel Hiram Chee , Mehran Bashiri , Joseph C. Eder
IPC分类号： A61B1804
CPC分类号： A61F2/88 , A61B17/12022 , A61B17/12118 , A61B17/12145 , A61B17/12154 , A61B2017/1205 , A61B2017/12063 , A61F2002/30092 , A61F2210/0014 , A61F2250/0039 , A61F2310/00023
摘要： This is an artificial occlusion kit for implanting and retaining an artificial occlusion device in a body space adjacent to and extending from a body lumen in a mammal. The includes at least one occlusion device and a retaining device for blocking the migration of the occlusion device out of the occlusion site. The retaining device is radially expandable at a retaining site adjacent the body space to be occluded to a diameter that is sufficient to engage the body lumen wall at the retaining site and form a barrier across the entrance zone of the body space to be occluded. The expanded retaining device also forms a lumen for flow through body lumen at the retaining site. At least one semi-penetrable space may also be provided in the retaining device, allowing introduction of occlusion devices into the body space to be occluded, but preventing subsequent migration of the occlusion devices out of the body space. This semi-penetrable space may also be distensible to allow for delivery of occlusion devices therethrough. An introducer wire or a tapered-tip delivery catheter may be used to distend the distensible space and deliver the occlusion devices. The retaining device structure may further include a radiopaque metal wire wound into a primary helix over an inner core member made of a superelastic alloy of nickel and titanium. An implantable medical device assembly is also provided, having the structure described for the retaining device of the novel artificial occlusion kit, and which is attached to an elongate pusher via a sacrificial link that is electrolytically dissolvable.
摘要翻译：这是一种用于将人工闭塞装置植入和保持在与哺乳动物的体腔相邻并从其延伸的身体空间中的人造闭塞套件。包括至少一个闭塞装置和用于阻挡闭塞装置移出闭塞部位的保持装置。保持装置可以在靠近身体空间的保持位置处径向展开，以被阻塞到直径足以与保持位置处的身体腔壁接合并形成穿过要被遮挡的身体空间的入口区域的屏障。扩张的保持装置还形成用于在保留位置处流过体腔的流明。还可以在保持装置中设置至少一个半透入空间，从而允许将遮挡装置引入身体空间以被阻塞，但是防止闭塞装置随后从身体空间中移出。这种半透入空间也可以是可扩张的，以允许通过其中的封闭装置的输送。导引线或锥形输送导管可用于扩张可扩张空间并输送遮挡装置。保持装置结构还可以包括在由镍和钛的超弹性合金制成的内芯构件上缠绕到主螺旋中的不透射线金属线。还提供了一种植入式医疗装置组件，其具有针对新型人造阻塞套件的保持装置所述的结构，并且经由电解可溶解的牺牲连接件连接到细长推动器。

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