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31. 发明申请

US20090191146A1 METHODS FOR THE MODULATION OF NEOVASCULARIZATION AND/OR THE GROWTH OF COLLATERAL ARTERIES AND/OR OTHER ARTERIES FROM PREEXISTING ARTERIOLAR CONNECTIONS 审中-公开
标题翻译：调查近期和/或殖民地和/或其他风险的增长的方法来自预防性干扰素连接
公开(公告)号：US20090191146A1
公开(公告)日：2009-07-30
申请号：US12332937
申请日：2008-12-11
申请人： IVO R. BUSCHMANN , Wolfgang Schaper
发明人： IVO R. BUSCHMANN , Wolfgang Schaper
IPC分类号： A61K38/00 , A61P9/00
CPC分类号： A61K38/193 , A61K48/00
摘要： Described is the modulation of the neovascularization and/or growth of collateral arteries and/or other arteries from preexisting arteriolar connections. Methods are provided for enhancing neovascularization and/or the growth of collateral arteries and/or other arteries from preexisting arteriolar connections comprising contacting organs, tissue or cells with a colony stimulating factor (CSF) or a nucleic acid molecule encoding said CSF. Furthermore, the use of a CSF or a nucleic acid molecule encoding said CSF for the preparation of pharmaceutical compositions for enhancing neovascularization and/or collateral growth of collateral arteries and/or other arteries from preexisting arteriolar connections is described. Also provided are methods for the treatment of tumors comprising contacting an organ, tissue or cells with an agent which suppresses neovascularization and/or the growth of collateral arteries and/or other arteries from preexisting arteriolar connections through the inhibition of the biological activity of CSFs. Described is further the use of an agent which suppresses neovascularization and/or the growth of collateral arteries and/or other arteries from preexisting arteriolar connections through inhibition of the biological activity of CSFs for the preparation of pharmaceutical compositions for the treatment of tumors.
摘要翻译：描述了来自预先存在的小动脉连接的侧支动脉和/或其他动脉的新生血管形成和/或生长的调节。提供了用于增强来自预先存在的小动脉连接的侧支动脉和/或其它动脉的新生血管形成和/或生长的方法，包括使器官，组织或细胞与集落刺激因子（CSF）或编码所述CSF的核酸分子接触。此外，描述了编码所述CSF用于制备用于增强来自预先存在的小动脉连接的侧支动脉和/或其他动脉的新生血管形成和/或侧支生长的药物组合物的CSF或核酸分子的用途。还提供了用于治疗肿瘤的方法，包括通过抑制CSF的生物学活性使器官，组织或细胞与抑制新生血管形成和/或副前动脉和/或其它动脉从预先存在的小动脉连接生长的药剂接触。还描述了通过抑制用于制备用于治疗肿瘤的药物组合物的CSF的生物活性来抑制来自预先存在的小动脉连接的侧支动脉和/或其它动脉的新生血管形成和/或生长的药剂的用途。

32. 发明申请

US20050256000A1 Quinoxalin-2-one derivatives, compositions which protect useful plants and comprise these derivatives, and processes for their preparation and their use 审中-公开
标题翻译：喹喔啉-2-酮衍生物，保护有用植物并包含这些衍生物的组合物，及其制备方法及其用途
公开(公告)号：US20050256000A1
公开(公告)日：2005-11-17
申请号：US11127016
申请日：2005-05-11
申请人： Wolfgang Schaper , Lothar Willms , Christopher Rosinger , Erwin Hacker , Eckhard Rose , Dirk Schmutzler
发明人： Wolfgang Schaper , Lothar Willms , Christopher Rosinger , Erwin Hacker , Eckhard Rose , Dirk Schmutzler
IPC分类号： A01N25/32 , A01N43/60 , A01N43/78 , A01N43/80 , A01N43/82 , C07D241/50 , C07D241/52 , C07D401/04 , C07D401/06 , C07D403/06 , C07D405/04 , C07D405/06 , C07D405/12 , C07D409/04 , C07D409/06 , C07D409/14 , C07D413/06 , C07D417/04 , C07D417/06 , C07D417/14 , C07D241/36
CPC分类号： C07D401/04 , A01N25/32 , A01N43/60 , A01N43/78 , A01N43/80 , A01N43/82 , C07D241/52 , C07D401/06 , C07D403/06 , C07D405/04 , C07D405/06 , C07D405/12 , C07D409/04 , C07D409/06 , C07D409/14 , C07D413/06 , C07D417/04 , C07D417/06 , C07D417/14 , A01N61/00 , A01N43/56 , A01N2300/00
摘要： Compounds of the formula (I) and salts thereof in which X is O or S; (Y)n=n substituents Y, n is 0, 1, 2, 3 or 4, R1 is H, OH, NH2, (C1-C4)-alkylamino, di-[(C1-C4)-alkyl]amino or optionally substituted (C1-C10)-alkyl, (C3-C10)-alkenyl, (C3-C10)-alkynyl or (C1-C10)-alkoxy, (C3-C10)-cycloalkyl, (C4-C10)-cycloalkenyl, aryl or heterocyclyl, R2 is H or optionally substituted (C1-C10)-alkyl, (C3-C10)-alkenyl, (C3-C10)-alkynyl, (C3-C10)-cycloalkyl, (C4-C10)-cycloalkenyl, aryl or heterocyclyl, where the radicals Y are as defined in claim 1 are suitable for use as safeners for crop plants or useful plants against the phytotoxic actions of agrochemicals such as pesticides in these plants.
摘要翻译：式（I）化合物及其盐，其中X为O或S; （Y）n n = n取代基Y，n为0,1,2,3或4，R 1为H，OH，NH 2 ，（C 1 -C 4 -C 4 - ） - 烷基氨基，二 - [（C 1 -C 4 - - 烷基]氨基或任选取代的（C 1 -C 10 - ） - 烷基，（C 3 -C 10 - ）） - 烯基，（C 3 -C 10） - 炔基或（C 1 -C 10 - ） - 炔基或（C 1 -C 10） - 烷氧基，（C 3 -C 10） - 环烷基，（C 4 -C 10 - ） - 环烯基，芳基或杂环基，R 2是H或任选取代的（C 1 -C 10 - ） - 烷基，（C 3 < （C 3 -C 10） - 炔基，（C 3 -C 10） - 烯基，（C 3 -C 10 - ） - 炔基，（C 3 -C 10） C 1 -C 10 - 环烷基，（C 1-4 -C 10 - ）环烯基，芳基或杂环基，其中基团Y如所定义权利要求1中适用于农作物植物或有用植物的安全剂，以防止这些植物中农药如农药的植物毒性作用。

33. 发明授权

US06265398B1 Substituted pyridines/pyrimidines, their preparation and their use as pesticides 失效
标题翻译：取代的吡啶/嘧啶，其制备及其作为农药的用途
公开(公告)号：US06265398B1
公开(公告)日：2001-07-24
申请号：US09177395
申请日：1998-10-23
申请人： Ralf Braun , Wolfgang Schaper , Herbert Stark , Rainer Preuss , Werner Knauf , Ulrich Sanft , Manfred Kern , Werner Bonin
发明人： Ralf Braun , Wolfgang Schaper , Herbert Stark , Rainer Preuss , Werner Knauf , Ulrich Sanft , Manfred Kern , Werner Bonin
IPC分类号： A61K31506
CPC分类号： C07D239/34 , A01N43/54 , C07D239/42 , C07D239/47 , C07D239/52 , C07D239/88 , C07D239/94 , C07D405/12
摘要： The present invention relates to novel substituted pyridines/pyrimidines of the formula I where A is CH or N; X is NH, O or S(O)q where q is 0, 1 or 2; Y1, Y2 and Y3 independently of one another are a group of the formula —O—, —CO—, —CNR6—, —S(O)r— or —N(O)lR6— where l is 0 or 1 and where r is 0, 1 or 2, or a group of the formula CR7R8, or Y1 or Y3 replace a direct bond; Z is a direct bond, NR9, O, S(O)s where s is 0, 1 or 2, OSO2, SO2O, NR10SO2, SO2NR11, SiR12R13 or where U is a direct bond, NR14 or O; W is oxygen or sulfur; V is a direct bond, NR15 or oxygen; m and n and 0, 1, 2, 3 or 4; where the radicals R1 to R15 have the meaning given in the description, to processes for their preparation, to their use as pesticides, fungicides and ovicides and to their use as veterinary medicaments.
摘要翻译：本发明涉及式I的新的取代吡啶/嘧啶，其中A是CH或N; X是NH，O或S（O）q，其中q是0,1或2; Y 1，Y 2和Y 3彼此独立地是基团-O - ， - CO - ， - NR 6 - ， - S（O）r - 或-N（O）lR 6 - ，其中l为0或1，并且其中r为0,1或2，式CR7R8，或Y1或Y3代替直接键; Z是直接键，NR 9，O，S（O）s，其中s是0,1或2，OSO 2，SO 2 O，NR 10 SO 2，SO 2 NR 11，SiR 12 R 13或其中U是直接键合，NR14或O; W是氧或硫; V是直接键，NR15或氧; m和n和0,1,2,3或4; 其中基团R1至R15具有说明书中给出的含义，其制备方法，用作杀虫剂，杀真菌剂和杀卵剂以及用作兽药。

34. 发明授权

US5859009A Substituted spiroalkylamino and alkoxy heterocycles, processes for their preparation, and their use as pesticides and fungicides 失效
标题翻译：取代的螺烷基氨基和烷氧基杂环，其制备方法及其作为农药和杀真菌剂的用途
公开(公告)号：US5859009A
公开(公告)日：1999-01-12
申请号：US540987
申请日：1995-10-11
申请人： Wolfgang Schaper , Rainer Preuss , Peter Braun , Manfred Kern , Werner Knauf , Burkhard Sachse , Ulrich Sanft , Anna Waltersdorfer , Werner Bonin , Adolf Linkies , Dieter Bernd Reuschling
发明人： Wolfgang Schaper , Rainer Preuss , Peter Braun , Manfred Kern , Werner Knauf , Burkhard Sachse , Ulrich Sanft , Anna Waltersdorfer , Werner Bonin , Adolf Linkies , Dieter Bernd Reuschling
IPC分类号： C07D239/34 , A01N43/40 , A01N43/54 , A61K31/44 , A61K31/4418 , A61K31/4427 , A61K31/443 , A61K31/4433 , A61K31/47 , A61K31/505 , A61P31/04 , C07D213/61 , C07D213/68 , C07D213/74 , C07D215/20 , C07D215/38 , C07D239/38 , C07D239/42 , C07D401/12 , C07D405/12 , C07D409/12 , C09D5/14 , C09K3/10 , C10M133/40
CPC分类号： C07D405/12 , A01N43/40 , A01N43/54 , C09D5/14 , C09K3/10 , C09K2200/0476
摘要： Substituted spiroalkylamino and -alkoxy heterocycles, processes for their preparation, and their use as pesticides and fungicidesThe invention relates to compounds of the formula ##STR1## in which Het is optionally substituted 4-pyridyl or 4-pyrimidinyl; X is NH, O or S(O).sub.0-2 ; E is a bond or alkanediyl; Y and Z are CH.sub.2, O and/or S(O).sub.0-2 ; W is (CH.sub.2).sub.0-4 ; R.sup.4 and R.sup.5 are halogen, (halo)alkyl, (halo)alkoxy or alkylthio; r and s are 0-2; U is a bond, O, S(O).sub.0-2 or optionally substituted imino; and V is a bond CO, SO.sub.2, --CQ--T-- or --CT'.dbd.N--; or U+V together are a double bond; and R.sup.6 is as defined in the description. The invention furthermore relates to processes for their preparation and to their use as pesticides and fungicides.
摘要翻译：取代的螺烷基氨基和 - 烷氧基杂环，其制备方法及其作为农药和杀真菌剂的用途本发明涉及式（I）的化合物，其中Het是任选取代的4-吡啶基或4-嘧啶基; X是NH，O或S（O）0-2; E是键或烷二基; Y和Z是CH 2，O和/或S（O）0-2; W是（CH 2）0-4; R4和R5是卤素，（卤代）烷基，（卤代）烷氧基或烷硫基; r和s为0-2; U是键，O，S（O）0-2或任选取代的亚氨基; 和V是键，CO，SO2，-CQ-T或-CT'= N-; 或U + V一起是双键; R6如说明书中所定义。本发明还涉及其制备方法及其作为农药和杀真菌剂的用途。

35. 发明申请

US20090304781A1 MASTER GENE OF ARTERIOGENESIS 审中-公开
标题翻译：主要成分的基因
公开(公告)号：US20090304781A1
公开(公告)日：2009-12-10
申请号：US12281467
申请日：2007-03-01
申请人： Wolfgang Schaper , Inka Eitenmüller , Kerstin Troidl , Christian Troidl , Matthias Heil , Thomas Schmitz-Rixen , Anton J.G. Horrevoets
发明人： Wolfgang Schaper , Inka Eitenmüller , Kerstin Troidl , Christian Troidl , Matthias Heil , Thomas Schmitz-Rixen , Anton J.G. Horrevoets
IPC分类号： A61K9/127 , A61K38/16 , A61K48/00 , A61K9/00 , C12N5/06 , C12Q1/68 , C07K16/00 , A61P9/10
CPC分类号： C07K14/475 , A61K38/00 , A61K38/1709 , A61K38/195 , G01N33/6893 , G01N2500/00 , G01N2800/32 , A61K2300/00
摘要： The present invention relates to a pharmaceutical composition comprising (a) a polynucleotide comprising or consisting of a nucleotide sequence encoding a polypeptide with the amino acid sequence as set forth in SEQ ID NO: 2; (b) a polynucleotide comprising or consisting of a nucleotide sequence which is a fragment of a nucleotide sequence encoding the polypeptide with the amino acid sequence as set forth in SEQ ID NO: 2, wherein the polypeptide encoded by said polynucleotide has arteriogenic activity; (c) a polynucleotide comprising or consisting of a nucleotide sequence encoding a polypeptide, wherein said polypeptide exhibits at least 70% sequence identity with the sequence of the polypeptide encoded by the polynucleotide of (a) or (b) over the entire length, and wherein said polypeptide has arteriogenic activity; and/or (d) a polypeptide encoded by the polynucleotide of any one of (a) to (c).
摘要翻译：本发明涉及药物组合物，其包含（a）包含编码具有SEQ ID NO：2所示的氨基酸序列的多肽的核苷酸序列或由其组成的多核苷酸; （b）包含编码具有SEQ ID NO：2所示的氨基酸序列的多肽的核苷酸序列的核苷酸序列的核苷酸序列的多核苷酸，其中由所述多核苷酸编码的多肽具有动脉生成活性; （c）包含编码多肽的核苷酸序列或由编码多肽的核苷酸序列组成的多核苷酸，其中所述多肽在整个长度上与由（a）或（b）的多核苷酸编码的多肽的序列具有至少70％的序列同一性，其中所述多肽具有动脉生成活性; 和/或（d）由（a） - （c）中任一个的多核苷酸编码的多肽。

36. 发明授权

US07507705B2 Methods for the modulation of neovascularization and/or the growth of collateral arteries and/or other arteries from preexisting arteriolar connections 失效
标题翻译：调节新生血管形成和/或来自预先存在的小动脉连接的侧支动脉和/或其他动脉生长的方法
公开(公告)号：US07507705B2
公开(公告)日：2009-03-24
申请号：US09509764
申请日：1998-10-01
申请人： Ivo R. Buschmann , Wolfgang Schaper
发明人： Ivo R. Buschmann , Wolfgang Schaper
IPC分类号： A61K38/00 , A01N37/18 , A61K31/70 , A01N43/04
CPC分类号： A61K38/193 , A61K48/00
摘要： Described is the modulation of the neovascularization and/or growth of collateral arteries and/or other arteries from preexisting arteriolar connections. Methods are provided for enhancing neovascularization and/or the growth of collateral arteries and/or other arteries from preexisting arteriolar connections comprising contacting organs, tissue or cells with a colony stimulating factor (CSF) or a nucleic acid molecule encoding a CSF. Furthermore, the use of a CSF or a nucleic acid molecule encoding a CSF for the preparation of pharmaceutical compositions for enhancing neovascularization and/or collateral growth of collateral arteries and/or other arteries from preexisting arteriolar connections is described. Also provided are methods for the treatment of tumors comprising contacting an organ, tissue or cells with an agent which suppresses neovascularization and/or the growth of collateral arteries and/or other arteries from preexisting arteriolar connections through the inhibition of the biological activity of CSFs. Described is further the use of an agent which suppresses neovascularization and/or the growth of collateral arteries and/or other arteries from preexisting arteriolar connections through inhibition of the biological activity of CSFs for the preparation of pharmaceutical compositions for the treatment of tumors.
摘要翻译：描述了来自预先存在的小动脉连接的侧支动脉和/或其他动脉的新生血管形成和/或生长的调节。提供了用于增强来自预先存在的小动脉连接的侧支动脉和/或其他动脉的新生血管形成和/或生长的方法，其包括使器官，组织或细胞与集落刺激因子（CSF）或编码CSF的核酸分子接触。此外，描述了使用CSF或编码CSF的核酸分子来制备用于增强来自预先存在的小动脉连接的侧支动脉和/或其他动脉的新生血管形成和/或侧支生长的药物组合物。还提供了用于治疗肿瘤的方法，包括通过抑制CSF的生物学活性使器官，组织或细胞与抑制新生血管形成和/或副前动脉和/或其它动脉从预先存在的小动脉连接生长的药剂接触。还描述了通过抑制用于制备用于治疗肿瘤的药物组合物的CSF的生物活性来抑制来自预先存在的小动脉连接的侧支动脉和/或其它动脉的新生血管形成和/或生长的药剂的用途。

37. 发明申请

US20060173022A1 Heterocyclic amides, method for the production thereof, substances containing said heterocyclic amides, and use thereof as pesticides 审中-公开
公开(公告)号：US20060173022A1
公开(公告)日：2006-08-03
申请号：US10547004
申请日：2004-02-19
申请人： Wolfgang Schaper
发明人： Wolfgang Schaper
IPC分类号： A61K31/506 , A61K31/455 , C07D239/42 , C07D213/46
CPC分类号： C07D213/82 , A01N43/40 , A01N43/50 , A01N43/52 , A01N43/54 , A01N43/653 , A01N43/713 , A01N43/76 , A01N43/78 , A01N43/82 , A01N43/84 , A01N47/12 , A01N47/14 , A01N47/24 , A01N47/28 , A01N47/34 , A01N47/38 , C07D401/12 , C07D405/12 , C07D409/12 , C07D413/12 , C07D417/12
摘要： Amides of the formula (I) and salts thereof wherein: A is CH or N; Y is O or S; n is 0 or 1; R1 is (C1-C4)-haloalkyl; R2 and R3 are identical or different and are hydrogen, (C1-C4)-alkyl, (C1-C4)-haloalkyl or halogen; R4 is hydrogen, (C1-C10)-alkyl, (C3-C10)-cycloalkyl, (C3-C10)-alkenyl or (C3-C10)-alkynyl, where in the alkyl, cycloalkyl, alkenyl or alkynyl groups mentioned up to three hydrogen atoms may be replaced by halogen, preferably fluorine or chlorine, in the case of fluorine also up to the maximum number; R5 is G1SR6, G1S(O)R7, G1S(O)2R8, G1OR9, G1NR10R11, G2CR12═NOR13, G1ON═CR14R15, G2CR12═N—NR16R17, G1NR13N═CR14R15, G1NR18NR19R20, G1ONR21R22, G1NR23OR24, G2CR10═N(+)(O(−))R12, R25 or G1R26; G1 is a straight-chain or branched (C2-C6)-alkylene moiety, the distance between the amide nitrogen and the radical R5 being at least C2; G2 is a straight-chain or branched (C1-C6)-alkylene moiety and R6 to R26 are as defined in the description; are suitable for controlling pests.

38. 发明授权

US06592862B1 Methods for the modulation of the growth of collateral arteries and/or other arteries from preexisting arteriolar connections 失效
标题翻译：用于调节来自预先存在的小动脉连接的侧支动脉和/或其他动脉生长的方法
公开(公告)号：US06592862B1
公开(公告)日：2003-07-15
申请号：US09402358
申请日：1999-12-10
申请人： Wolfgang Schaper , Wulf D. Ito
发明人： Wolfgang Schaper , Wulf D. Ito
IPC分类号： A61K3819
CPC分类号： A61K38/1793 , A61K38/195 , A61K48/00
摘要： Described is the modulation of the growth of collateral arteries and/or other arteries from preexisting arterlolar connections. Methods are provided for enhancing the growth of collateral arteries and/or other arteries from preexisting arteriolar connections comprising contacting tissue or cells with a monocyte chemotactic protein (MCP) or a nudeic acid molecule encoding said MCP. Furthermore, the use of a MCP or a nucleic acid molecule encoding said MCP for the preparation of pharmaceutical compositions for enhancing collateral growth of collateral arteries and/or other arteries from preexisting arteriolar connections is described, Also provided are methods for the treatment of tumors comprising contacting tissue or cells with an agent which suppresses the growth of collateral arteries and/or other arteries from preexisting arteriolar connections through the attraction of monocytes. Described is further the use of an agent which suppresses the growth of collateral arteries and/or other arteries from preexisting arteriolar connections through attraction of monocytes for the preparation of pharmaceutical compositions for the treatment of tumors.
摘要翻译：描述了来自预先存在的动脉关节连接的侧支动脉和/或其他动脉的生长的调节。提供了用于增强来自预先存在的小动脉连接的侧支动脉和/或其他动脉的生长的方法，其包括使组织或细胞与编码所述MCP的单核细胞趋化蛋白（MCP）或裸露酸分子接触。此外，还描述了使用MCP或编码所述MCP的核酸分子来制备用于增强来自预先存在的小动脉连接的侧支动脉和/或其他动脉的侧支生长的药物组合物，还提供了治疗肿瘤的方法，包括使组织或细胞与通过单核细胞的吸引抑制来自预先存在的小动脉连接的侧支动脉和/或其它动脉的生长的药剂接触。还描述了通过吸引单核细胞来制备用于治疗肿瘤的药物组合物来抑制来自预先存在的小动脉连接的侧支动脉和/或其它动脉生长的药剂的用途。

39. 发明授权

US06207668B1 Substituted pyridines/pyrimidines, their preparation, and their use as pesticides 失效
标题翻译：取代的吡啶/嘧啶，它们的制备及其作为农药的用途
公开(公告)号：US06207668B1
公开(公告)日：2001-03-27
申请号：US08829841
申请日：1997-04-01
申请人： Ralf Braun , Wolfgang Schaper , Werner Knauf , Ulrich Sanft , Manfred Kern , Werner Bonin
发明人： Ralf Braun , Wolfgang Schaper , Werner Knauf , Ulrich Sanft , Manfred Kern , Werner Bonin
IPC分类号： A01N4354
CPC分类号： C07D403/12 , A01N43/54 , A01N47/38 , C07D405/12
摘要： The present invention relates to novel substituted pyridines/pyrimidines of the formula I where A is CH or N; X is NH, oxygen or S(O)q where q is 0, 1 or 2; Y is a direct bond or CH2; Z is oxygen, NR7 or S(O)m is 0, 1 or 2, and the radicals R1, R2, R3, R4, R5, R6 and R7 are as defined in the description, to processes for their preparation, and to their use as pesticides, fungicides, ovicides or as veterinary medicaments.
摘要翻译：本发明涉及式I的新的取代的吡啶/嘧啶，其中A是CH或N; X是NH，氧或S（O）q，其中q是0,1或2; Y是直接键或CH2; Z是氧，NR 7或S（O）m是0,1或2，基团R 1，R 2，R 3，R 4，R 5，R 6和R 7如说明书中所定义，其制备方法及其制备方法用作杀虫剂，杀真菌剂，杀卵剂或兽药。

40. 发明授权

US4465669A Angiotropins of leukocytes and inflamed tissue, process for their biotechnical preparation, and pharmaceutical compositions thereof 失效
标题翻译：白细胞和发炎组织的促肾上腺皮质，其生物技术制备方法及其药物组合物
公开(公告)号：US4465669A
公开(公告)日：1984-08-14
申请号：US357814
申请日：1982-03-15
申请人： Josef H. Wissler , Wolfgang Schaper
发明人： Josef H. Wissler , Wolfgang Schaper
IPC分类号： A61K39/395 , A61K35/14 , A61K35/34 , A61K38/00 , A61K38/16 , A61K38/22 , C07K14/435 , C07K14/515 , C07K16/22 , C12N5/02 , A61K37/00
CPC分类号： C07K14/515 , C07K16/22 , A61K38/00
摘要： The invention relates to new angiotropins of leukocytes and inflamed tissuehich have the biological and physicochemical properties stated in the patent claims. The compounds selectively stimulate the directional growth of blood vessels and lead to a neovascularization of tissue. The invention also relates to a biotechnical process for preparing and isolating the angiotropins and to pharmaceutical compositions containing them.
摘要翻译：本发明涉及具有在专利权利要求中所述的生物学和物理化学性质的白细胞和发炎组织的新型促黄体素。这些化合物选择性地刺激血管的定向生长并导致组织的新生血管形成。本发明还涉及用于制备和分离促弹药的生物技术方法和含有它们的药物组合物。

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