专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

31. 发明申请

WO2007125354A2 MASS SPECTROMETER 审中-公开
标题翻译：质谱仪
公开(公告)号：WO2007125354A2
公开(公告)日：2007-11-08
申请号：PCT/GB2007001589
申请日：2007-04-30
申请人： MICROMASS LTD , GREEN MARTIN , WILDGOOSE JASON LEE , PRINGLE STEVEN DEREK , KENNY DANIEL JAMES
发明人： GREEN MARTIN , WILDGOOSE JASON LEE , PRINGLE STEVEN DEREK , KENNY DANIEL JAMES
CPC分类号： H01J49/4235 , H01J49/065
摘要： An ion guide or mass analyser (2) is disclosed comprising a plurality of electrodes (2a) having apertures through which ions are transmitted in use. A pseudo-potential barrier is created at the exit of the ion guide or mass analyser (2). The amplitude or depth of the pseudo-potential barrier is inversely proportional to the mass to charge ratio of an ion. One or more transient DC voltages (4) are applied to the electrodes (2a) of the ion guide or mass analyser (2) in order to urge ions along the length of the ion guides or mass analyser (2). The amplitude of the transient DC voltage (4) applied to the electrode (2a) may be increased with time so that ions are caused to be emitted from the ion guide or mass analyser (2) in reverse order of their mass to charge ratio.
摘要翻译：公开了一种离子导向器或质量分析器（2），其包括具有孔的多个电极（2a），在使用中通过该孔具有离子。在离子导向器或质量分析器（2）的出口处产生伪势垒。伪势垒的幅度或深度与离子的质荷比成反比。一个或多个瞬态DC电压（4）被施加到离子导向器或质量分析器（2）的电极（2a），以促使沿着离子导向器或质量分析器（2）的长度的离子。施加到电极（2a）的瞬态直流电压（4）的振幅可以随时间增加，使得离子以其质荷比相反的顺序从离子导向器或质量分析器（2）发射。

32. 发明申请

WO2006090138A2 MASS SPECTROMETER 审中-公开
标题翻译：质谱仪
公开(公告)号：WO2006090138A2
公开(公告)日：2006-08-31
申请号：PCT/GB2006000613
申请日：2006-02-22
申请人： MICROMASS LTD , GREEN MARTIN , WILDGOOSE JASON LEE , GORENSTEIN MARC V
发明人： GREEN MARTIN , WILDGOOSE JASON LEE , GORENSTEIN MARC V
IPC分类号： H01J49/40
CPC分类号： H01J49/025 , H01J49/0036 , H01J49/40
摘要： A method of mass spectrometry is disclosed wherein distortions in a mass spectrum are corrected for by determining or estimating the number of ions Q i which arrived in an i th time bin, wherein: Formula (I) and wherein q i is the actual total number of ion arrival events recorded in the i th time bin and x is an integer corresponding to the number of time bins which correspond with an estimated deadtime period.
摘要翻译：公开了一种质谱法，其中通过确定或估计到达第i个时间仓的离子数Q i校正质谱中的失真，其中：式（I），其中q i i i是在第i个时间仓中记录的离子到达事件的实际总数，x是与时间数相对应的整数与预计的死时间相对应的箱子。

33. 发明申请

WO2012085594A2 IMPROVED SPACE FOCUS TIME OF FLIGHT MASS SPECTROMETER 审中-公开
标题翻译：改进飞行质谱仪空间聚焦时间
公开(公告)号：WO2012085594A2
公开(公告)日：2012-06-28
申请号：PCT/GB2011052576
申请日：2011-12-22
申请人： MICROMASS LTD , HOYES JOHN BRIAN , LANGRIDGE DAVID J , WILDGOOSE JASON LEE
发明人： HOYES JOHN BRIAN , LANGRIDGE DAVID J , WILDGOOSE JASON LEE
IPC分类号： H01J49/40
CPC分类号： H01J49/403 , H01J49/0027 , H01J49/401
摘要： A Time of Flight mass spectrometer is disclosed wherein a fifth order spatial focusing device is provided. The device which may comprise an additional stage in the source region of the Time of Flight mass analyser is arranged to introduce a non-zero fifth order spatial focusing term so that the combined effect of first, third and fifth order spatial focusing terms results in a reduction in the spread of ion arrival times ?T of ions arriving at the ion detector.
摘要翻译：公开了一种飞行时间质谱仪，其中提供了五阶空间聚焦装置。可以包括飞行时间质量分析器的源区域中的附加阶段的装置被布置为引入非零五阶空间聚焦项，使得第一，第三和第五阶空间聚焦项的组合效果导致a 减少离子到达离子检测器的离子到达时间ΔT的扩散。

34. 发明申请

WO2008090365A3 MASS SPECTROMETER 审中-公开
标题翻译：质谱仪
公开(公告)号：WO2008090365A3
公开(公告)日：2009-07-02
申请号：PCT/GB2008000275
申请日：2008-01-25
申请人： MICROMASS LTD , PRINGLE STEVEN DEREK , WILDGOOSE JASON LEE
发明人： PRINGLE STEVEN DEREK , WILDGOOSE JASON LEE
IPC分类号： H01J49/00
CPC分类号： H01J49/428
摘要： A mass spectrometer is disclosed comprising a quadrupole rod set ion guide or mass filter device. Broadband frequency-signals (13, 14, 15) having a plurality of frequency notches (16a; 16b; 16c) are applied sequentially to the rods of the quadrupole rod set. The notched broadband frequency signals (16a, 16b, 16c) cause undesired ions to be resonantly or parametrically ejected from the ion guide. The resulting ion signals are deconvoluted to provide a mass spectrum.
摘要翻译：公开了一种质谱仪，其包括四极杆组离子导向器或质量过滤装置。具有多个频率切口（16a; 16b; 16c）的宽带频率信号（13,14,15）依次施加到四极杆组的杆上。缺口宽带频率信号（16a，16b，16c）使离子引导不需要的离子共振或参数地喷出。所得到的离子信号被去卷积以提供质谱。

35. 发明申请

WO2008087389A2 MASS SPECTROMETER 审中-公开
标题翻译：质谱仪
公开(公告)号：WO2008087389A2
公开(公告)日：2008-07-24
申请号：PCT/GB2008000121
申请日：2008-01-15
申请人： MICROMASS LTD , KENNY DANIEL JAMES , WILDGOOSE JASON LEE
发明人： KENNY DANIEL JAMES , WILDGOOSE JASON LEE
CPC分类号： H01J49/401
摘要： A Time of Flight mass analyser is disclosed wherein the time period between successive orthogonal acceleration pulses is less than the time of flight of ions having the maximum mass to charge ratio of interest. As a result, some ions are subject to wrap-around and will appear in a subsequent mass spectrum. Mass spectra obtained at two different sampling rates may be compared and mass peaks relating to ions which have and have not been subject to wrap-around may be identified.
摘要翻译：公开了一种飞行时间质量分析器，其中连续正交加速脉冲之间的时间段小于具有最大质荷比的离子的飞行时间。结果，一些离子被卷绕并将出现在随后的质谱中。可以比较以两种不同采样速率获得的质谱，并且可以鉴定与已经和未被卷绕的离子有关的质谱峰。

36. 发明申请

WO2007052025A2 MASS SPECTROMETER 审中-公开
标题翻译：质谱仪
公开(公告)号：WO2007052025A2
公开(公告)日：2007-05-10
申请号：PCT/GB2006004078
申请日：2006-11-01
申请人： MICROMASS LTD , PRINGLE STEVEN DEREK , WILDGOOSE JASON LEE
发明人： PRINGLE STEVEN DEREK , WILDGOOSE JASON LEE
IPC分类号： H01J49/42
CPC分类号： H01J49/062 , H01J49/004 , H01J49/4235 , H01J49/427
摘要： A mass analyser (2) is provided comprising a plurality of electrodes having apertures through which ions are transmitted in use. A plurality of seudo-potential corrugations are created along the axis of the mass analyser (2). The amplitude or depth of the pseudo-potential corrugations is inversely proportional to the mass to charge ratio of an ion. One or more transient DC voltages are applied to the electrodes of the mass analyser (2) in order to urge ions along the length of the mass analyser (2). The amplitude of the transient DC voltages applied to the electrodes is increased with time and ions are caused to be emitted from the mass analyser (2) in reverse order of mass to charge ratio .
摘要翻译：提供质量分析器（2），其包括具有孔的多个电极，在使用中离子通过该孔传输。沿着质量分析器（2）的轴线产生多个潜在的波纹。伪电位波纹的幅度或深度与离子的质荷比成反比。一个或多个瞬态直流电压被施加到质量分析器（2）的电极，以促使离子沿着质量分析器（2）的长度。施加到电极的瞬态直流电压的幅度随着时间而增加，并且使质子分析器（2）以质荷比的相反顺序发射离子。

37. 发明申请

WO03050843A2 METHOD OF MASS SPECTROMETRY 审中-公开
标题翻译：质谱法
公开(公告)号：WO03050843A2
公开(公告)日：2003-06-19
申请号：PCT/GB0205628
申请日：2002-12-12
申请人： MICROMASS LTD , BATEMAN ROBERT HAROLD , HOYES JOHN BRIAN , WILDGOOSE JASON LEE , GILBERT ANTHONY JAMES
发明人： BATEMAN ROBERT HAROLD , HOYES JOHN BRIAN , WILDGOOSE JASON LEE , GILBERT ANTHONY JAMES
IPC分类号： H01J49/42 , H01J49/00
CPC分类号： H01J49/062
摘要： A method of mass spectrometry is disclosed wherein ions are trapped for a period of time T within an AC or RF ion guide maintained at a pressure P wherein the product P x T is at least 1 mbar-ms. The effect of trapping the ions according to a preferred embodiment is that singly charged ions which may, for example, comprise unwanted background ions are substantially lost from the trap whereas multiply charged analyte ions are maintained within the ion trap and can then be released for subsequent mass analysis.
摘要翻译：公开了一种质谱法，其中将离子俘获在维持在压力P的AC或RF离子导向器内的一段时间T内，其中产物P x T至少为1毫巴。捕获根据优选实施方案的离子的效果是，可以例如包含不想要的背景离子的单电荷离子从捕获阱基本上丢失，而多电荷分析物离子保持在离子阱内，然后可以释放以用于随后的质量分析。

38. 发明申请

WO2015189552A8 CONTROLLING GAS-PHASE ION INTERACTIONS 审中-公开
标题翻译：控制气相离子相互作用
公开(公告)号：WO2015189552A8
公开(公告)日：2017-03-02
申请号：PCT/GB2015000184
申请日：2015-06-15
申请人： MICROMASS LTD
发明人： GREEN MARTIN RAYMOND , WILDGOOSE JASON LEE
IPC分类号： G01N27/62
CPC分类号： G01N27/624 , H01J49/0031 , H01J49/0422 , H01J49/421
摘要： A mass spectrometer or ion mobility spectrometer is disclosed comprising: a first device for separating ions or molecules according to a physicochemical property (3); an ion mobility separation device (4) for receiving and separating at least some of said ions or ions derived from said molecules according to their ion mobility; a gas supply (6-10) connected to said ion mobility separation device (4) for supplying gas into said ion mobility separation device (4); and a control system (11) configured to adjust said gas supply (6-10) so as to change the composition of gas within the ion mobility separation device (4) as a function of time.
摘要翻译：公开了质谱仪或离子迁移谱仪，其包括：用于根据物理化学性质（3）分离离子或分子的第一装置; 离子迁移率分离装置（4），用于根据其离子迁移率接收和分离衍生自所述分子的至少一些所述离子或离子; 连接到所述离子迁移率分离装置（4）的用于将气体供应到所述离子迁移率分离装置（4）中的气体供应装置（6-10）; 以及控制系统（11），其被配置为调节所述气体供应（6-10），以便随着时间的推移改变离子迁移率分离装置（4）内的气体的组成。

39. 发明申请

WO2013171501A3 ORTHOGONAL ACCELERATION COAXIAL CYLINDER TIME OF FLIGHT MASS ANALYSER 审中-公开
标题翻译：飞行质量分析仪的正交加速同轴气缸时间
公开(公告)号：WO2013171501A3
公开(公告)日：2014-07-17
申请号：PCT/GB2013051271
申请日：2013-05-16
申请人： MICROMASS LTD
发明人： HOYES JOHN BRIAN , LANGRIDGE DAVID J , WILDGOOSE JASON LEE
IPC分类号： H01J49/40
CPC分类号： H01J49/401 , H01J49/0031 , H01J49/405 , H01J49/406 , H01J49/408
摘要： A Time of Flight mass analyser is disclosed comprising an annular ion guide having a longitudinal axis and comprising a first annular ion guide section and a second annular ion guide section. Ions are introduced into the first annular ion guide section so that the ions form substantially stable circular orbits within the first annular ion guide section about the longitudinal axis. The ions are then orthogonally accelerated ions from the first annular ion guide section into the second annular ion guide section. An ion detector is disposed within the annular ion guide and has an ion detecting surface arranged in a plane which is substantially perpendicular to the longitudinal axis.
摘要翻译：公开了一种飞行时间质量分析器，其包括具有纵向轴线的环形离子引导件，并且包括第一环形离子引导部分和第二环形离子引导部分。离子被引入到第一环形离子引导部分中，使得离子在第一环形离子引导部分内围绕纵向轴线形成基本上稳定的圆周轨道。然后离子是从第一环形离子引导部分到第二环形离子引导部分的正交加速离子。离子检测器设置在环形离子引导件内，并且具有布置在基本上垂直于纵向轴线的平面中的离子检测表面。

40. 发明申请

WO2013171459A3 METHOD OF IDENTIFYING PRECURSOR IONS 审中-公开
标题翻译：识别前体离子的方法
公开(公告)号：WO2013171459A3
公开(公告)日：2014-06-26
申请号：PCT/GB2013051199
申请日：2013-05-09
申请人： MICROMASS LTD
发明人： WILDGOOSE JASON LEE
IPC分类号： H01J49/00
CPC分类号： H01J49/0045 , H01J49/0031 , H01J49/0036 , H01J49/40
摘要： A method of mass spectrometry is disclosed comprising mass selectively transmitting precursor ions from a mass analyser into a fragmentation or reaction device, wherein the mass to charge ratios of the ions transmitted varies with time; fragmenting the precursor ions in the fragmentation or reaction device so as to produce fragment or product ions; mass analysing the fragment or product ions; determining the start and end times at which a first fragment or product ion is detected; using said start and end times to determine the start and end times at which a precursor ion of said first fragment or product ion is transmitted by said mass analyser; and using the start and end times at which the precursor ion is transmitted by said mass analyser to determine a mass to charge ratio of said precursor ion. The present invention enables precursor ion peaks to be resolved from the fragment data even when a low resolution mass analyser is used to analyse the precursor ions.
摘要翻译：公开了一种质谱方法，其包括质量选择性地将前体离子从质量分析器传输到碎裂或反应装置中，其中传输的离子的质荷比随时间变化; 将片段或反应装置中的前体离子破碎，以产生片段或产物离子; 大量分析片段或产物离子; 确定检测到第一片段或产物离子的开始和结束时间; 使用所述开始和结束时间来确定由所述质量分析器传输所述第一碎片或产物离子的前体离子的开始和结束时间; 并且使用由所述质量分析器传输所述前体离子的开始和结束时间以确定所述前体离子的质荷比。本发明即使当使用低分辨率质量分析器来分析前体离子时，也能够从片段数据中分离前体离子峰。

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式