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    • 32. 再颁专利
    • Electrode with improved signal to noise ratio
    • 具有提高信噪比的电极
    • USRE38775E1
    • 2005-08-16
    • US10285659
    • 2002-10-30
    • Ronald T. KurnikJanet TamadaMichael J. Tierney
    • Ronald T. KurnikJanet TamadaMichael J. Tierney
    • A61B5/0408A61B5/00A61B5/145A61B5/1477C12Q1/54G01N27/30G01N27/327
    • A61B5/1486C12Q1/54
    • An electrode assembly for sensing an electrochemical signal diffused from a source to a working electrode which is comprised of a plurality of substantially separated working electrode surfaces is disclosed. The electrode of the invention is comprised of 1) a working electrode made up of a plurality of working electrode surfaces or components and 2) a electrically insulating gap defined by adjacent edges of 1) insulating the working electrode surfaces or components from each other. The working electrode components are configured to receive electrochemical signal from two or preferably three dimensions simultaneously. The working electrode components configured over the same surface as a single electrode provide (1) an improved signal to noise ratio as compared to a single electrode by reducing noise, and (2) provide an overall enhanced signal after sensing for a given period of time.
    • 公开了一种用于感测从源极扩散到工作电极的电化学信号的电极组件,其由多个基本上分离的工作电极表面组成。 本发明的电极包括1)由多个工作电极表面或部件组成的工作电极,以及2)由相邻边缘限定的电绝缘间隙,1)将工作电极表面或部件彼此绝缘。 工作电极部件被配置成从两个或优选三个维度同时接收电化学信号。 配置在与单个电极相同的表面上的工作电极组件提供(1)通过降低噪声与单个电极相比提高了信噪比,以及(2)在感测到给定时间段之后提供总体增强的信号 。
    • 33. 发明授权
    • Stereo imaging system and method for use in telerobotic systems
    • 立体成像系统和用于远程遥控系统的方法
    • US06720988B1
    • 2004-04-13
    • US09378173
    • 1999-08-20
    • David GereChristopher R. BurnsJohn D. SternMichael J. Tierney
    • David GereChristopher R. BurnsJohn D. SternMichael J. Tierney
    • H04N1300
    • G02B23/2415A61B1/00183A61B1/00193H04N13/10H04N13/239H04N13/246H04N13/296H04N13/327H04N2005/2255
    • This invention relates to a stereo imaging system for use in telerobotic systems. A method of imaging a target site in a stereo imaging system is provided. The method typically includes capturing a right and a left optical image of the target site and transforming the right and the left optical images preferably into digital information. The method further includes converting the digital information into opposed images of the target site displayed on a stereo display of the stereo imaging system, one of the opposed images being associated with the right optical image and the other of the opposed images being associated with the left optical image. The method further includes regulating the digital information to cause the positions of the target site displayed on the opposed images to change relative to each other. The invention further provides for a method of aligning the opposed images, to a method of adjusting the stereo working distance of an image capture device, such as an endoscope and to a stereo imaging system.
    • 本发明涉及一种用于远程遥控系统的立体成像系统。 提供了一种在立体成像系统中成像目标部位的方法。 该方法通常包括捕获目标站点的右光学图像和左光学图像,并将左右光学图像优选地变换为数字信息。 该方法还包括将数字信息转换为立体成像系统的立体显示器上显示的目标站点的相对图像,相对图像中的一个与右光学图像相关联,另一个相对的图像与左侧相关联 光学图像。 所述方法还包括调节所述数字信息以使所述相对图像上显示的所述目标站点的位置相对于彼此改变。 本发明还提供了一种将相对图像对准的方法,一种调整诸如内窥镜和立体成像系统的图像捕获装置的立体声工作距离的方法。
    • 35. 发明授权
    • Electrochemical sensor with dual purpose electrode
    • 具有双用途电极的电化学传感器
    • US5954685A
    • 1999-09-21
    • US653161
    • 1996-05-24
    • Michael J. Tierney
    • Michael J. Tierney
    • A61B5/00A61N1/30A61B1/30
    • A61B5/1486
    • The present invention provides an electrode assembly for use in a transdermal analyte sensor operating in an alternating polarity mode in which a single electrode element provides both the counter electrode and iontophoretic electrode functions. By combining both the functions of the iontophoretic and counter electrode, the surface area of the electrode with respect to each function may be made larger. In turn this increases the ability of the electrode to deliver the required electrical field over a larger area when operating in the iontophoretic mode as well as increasing the ability of the counter electrode to compensate for the larger sensing electrode facilitated by this new design.
    • 本发明提供一种用于以交替极性模式操作的透皮分析物传感器的电极组件,其中单个电极元件提供对电极和离子电渗电极功能。 通过组合离子电渗和对电极的功能,可以使电极相对于每个功能的表面积更大。 反过来,这增加了当以离子电渗方式操作时电极在较大面积上输送所需电场的能力以及增加对电极补偿由该新设计促进的较大传感电极的能力。
    • 37. 发明授权
    • Electrochemical sensor ink compositions, electrodes, and uses thereof
    • 电化学传感器油墨组合物,电极及其用途
    • US07731867B2
    • 2010-06-08
    • US11656675
    • 2007-01-23
    • Huawen LiMichael J. Tierney
    • Huawen LiMichael J. Tierney
    • H01B1/22G01N27/327
    • C09D11/52C09D11/101C09D11/30G01N27/3271
    • The invention is directed to conductive polymer compositions, catalytic ink compositions (e.g., for use in screen-printing), electrodes produced by deposition of an ink composition, as well as methods of making, and methods of using such compositions and electrodes. An exemplary ink material comprises a metal catalyst (e.g., platinum black and/or platinum-on-carbon), graphite as a conducting material, a polymer binding material, and an organic solvent. In one aspect, the polymer binding material comprises a polymer binder blend comprising first and second polymers, wherein the first polymer has a glass transition temperature higher than the second polymer. In a second aspect, the polymer binding material comprises a hydrophilic acrylic polymer, copolymer, or terpolymer. The conductive polymer compositions of the present invention may be used, for example, to make electrochemical sensors. Such sensors may be used, for example, in a variety of devices to monitor analyte amount or concentrations in subjects.
    • 本发明涉及导电聚合物组合物,催化油墨组合物(例如,用于丝网印刷),通过沉积油墨组合物制备的电极,以及制备方法,以及使用这种组合物和电极的方法。 示例性的油墨材料包括金属催化剂(例如,铂黑和/或铂 - 碳),作为导电材料的石墨,聚合物粘合材料和有机溶剂。 一方面,聚合物结合材料包括包含第一和第二聚合物的聚合物粘合剂共混物,其中第一聚合物的玻璃化转变温度高于第二聚合物。 在第二方面,聚合物粘合材料包括亲水丙烯酸聚合物,共聚物或三元共聚物。 本发明的导电聚合物组合物可用于例如制造电化学传感器。 这种传感器可以用于例如各种装置中以监测受试者中的分析物量或浓度。