专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

31. 发明授权

US08285377B2 Pacing, sensing and other parameter maps based on localization system data 有权
标题翻译：基于定位系统数据的起搏，感应和其他参数图
公开(公告)号：US08285377B2
公开(公告)日：2012-10-09
申请号：US12553413
申请日：2009-09-03
申请人： Stuart Rosenberg , Kyungmoo Ryu , Allen Keel , Wenbo Hou , Thao Thu Nguyen , Steve Koh , Kjell Noren , Michael Yang
发明人： Stuart Rosenberg , Kyungmoo Ryu , Allen Keel , Wenbo Hou , Thao Thu Nguyen , Steve Koh , Kjell Noren , Michael Yang
IPC分类号： A61N1/362
CPC分类号： A61N1/3627 , A61N1/36521 , A61N1/36585 , A61N1/368 , A61N1/3684
摘要： An exemplary method generates a map of a pacing parameter, a sensing parameter or one or more other parameters based in part on location information acquired using a localization system configured to locate electrodes in vivo (i.e., within a patient's body). Various examples map capture thresholds, qualification criteria for algorithms, undesirable conditions and sensing capabilities. Various other methods, devices, systems, etc., are also disclosed.
摘要翻译：一种示例性方法基于部分地基于使用配置成在体内（即，在患者体内）定位电极的定位系统获取的位置信息来生成起搏参数，感测参数或一个或多个其它参数的图。各种示例映射捕获阈值，算法的资格标准，不良条件和感测能力。还公开了各种其它方法，装置，系统等。

32. 发明申请

US20110118803A1 Cardiac Resynchronization Therapy Optimization Using Vector Measurements Obtained From Realtime Electrode Position Tracking 有权
标题翻译：使用从实时电极位置跟踪获得的矢量测量的心脏再同步治疗优化
公开(公告)号：US20110118803A1
公开(公告)日：2011-05-19
申请号：US12621397
申请日：2009-11-18
申请人： Wenbo Hou , Stuart Rosenberg , Kyungmoo Ryu , Allen Keel , Steve Koh , Thao Thu Nguyen , Kjell Norén , Michael Yang
发明人： Wenbo Hou , Stuart Rosenberg , Kyungmoo Ryu , Allen Keel , Steve Koh , Thao Thu Nguyen , Kjell Norén , Michael Yang
IPC分类号： A61N1/365
CPC分类号： A61N1/3627 , A61B5/0205 , A61B5/04011 , A61B5/0424 , A61B5/053 , A61B5/0538 , A61B5/063 , A61N1/3684 , A61N1/3686
摘要： An exemplary method includes selecting a first pair of electrodes to define a first vector and selecting a second pair of electrodes to define a second vector; acquiring position information during one or more cardiac cycles for the first and second pairs of electrodes wherein the acquiring comprises using each of the electrodes for measuring one or more electrical potentials in an electrical localization field established in the patient; and determining a dyssynchrony index by applying a cross-covariance technique to the position information for the first and the second vectors. Another method includes determining a phase shift based on the acquired position information for the first and the second vectors; and determining an interventricular delay based at least in part on the phase shift.
摘要翻译：一种示例性方法包括选择第一对电极以限定第一矢量并选择第二对电极以限定第二矢量; 在所述第一和第二对电极的一个或多个心动周期期间获取位置信息，其中所述获取包括使用每个所述电极来测量在所述患者中建立的电定位区域中的一个或多个电位; 以及通过将交叉协方差技术应用于所述第一和第二向量的位置信息来确定不同步索引。另一种方法包括基于所获取的第一和第二矢量的位置信息来确定相移; 以及至少部分地基于所述相移来确定心室间延迟。

33. 发明申请

US20090306732A1 CARDIAC RESYNCHRONIZATION THERAPY OPTIMIZATION USING ELECTROMECHANICAL DELAY FROM REALTIME ELECTRODE MOTION TRACKING 有权
标题翻译：使用电动延迟从实际电极运动跟踪的心脏再生治疗优化
公开(公告)号：US20090306732A1
公开(公告)日：2009-12-10
申请号：US12416771
申请日：2009-04-01
申请人： Stuart Rosenberg , Allen Keel , Kyungmoo Ryu , Wenbo Hou , Kjell Noren , Thao Thu Nguyen , Michael Yang
发明人： Stuart Rosenberg , Allen Keel , Kyungmoo Ryu , Wenbo Hou , Kjell Noren , Thao Thu Nguyen , Michael Yang
IPC分类号： A61N1/362
CPC分类号： A61N1/3627 , A61B5/0422 , A61B5/0452 , A61B5/1107 , A61B5/6876 , A61B2562/043 , A61N1/36514 , A61N1/36578 , A61N1/3684 , A61N1/37252
摘要： An exemplary method includes providing a mechanical activation time (MA time) for a myocardial location, the location defined at least in part by an electrode and the mechanical activation time determined at least in part by movement of the electrode; providing an electrical activation time (EA time) for the myocardial location; and determining an electromechanical delay (EMD) for the myocardial location based on the difference between the mechanical activation time (MA time) and the electrical activation time (EA time).
摘要翻译：示例性方法包括提供用于心肌位置的机械活化时间（MA时间），至少部分地由电极限定的位置和至少部分地通过电极的移动确定的机械激活时间; 为心肌位置提供电激活时间（EA时间）; 并且基于机械激活时间（MA时间）和电激活时间（EA时间）之间的差异来确定心肌位置的机电延迟（EMD）。

34. 发明授权

US08983604B2 Closed-loop systems and methods for controlling neurostimulation based on far-field cardiac signals sensed by a spinal cord stimulation device 有权
标题翻译：基于由脊髓刺激装置感测到的远场心脏信号的闭环系统和用于控制神经刺激的方法
公开(公告)号：US08983604B2
公开(公告)日：2015-03-17
申请号：US13838305
申请日：2013-03-15
申请人： Allen Keel , Stuart Rosenberg , Rupinder Bharmi , Kyungmoo Ryu , Edward Karst , Fujian Qu , Xiaoyi Min , Yelena Nabutovsky
发明人： Allen Keel , Stuart Rosenberg , Rupinder Bharmi , Kyungmoo Ryu , Edward Karst , Fujian Qu , Xiaoyi Min , Yelena Nabutovsky
IPC分类号： A61N1/365 , A61N1/36
CPC分类号： A61N1/36114 , A61N1/36139
摘要： Techniques are provided for controlling spinal cord stimulation (SCS) or other forms of neurostimulation. Far-field cardiac electrical signals are sensed using a lead of the SCS device and neurostimulation is selectively delivering using a set of adjustable SCS control parameters. Parameters representative of cardiac rhythm are derived from the far-field cardiac electrical signals. The parameters representative of cardiac rhythm are correlated with SCS control parameters to thereby map neurostimulation control settings to cardiac rhythm parameters. The delivery of further neurostimulation is then controlled based on the mapping of neurostimulation control settings to cardiac rhythm parameters to, for example, address any cardiovascular disorders detected based on the far-field cardiac signals. In this manner, a closed loop control system is provided to automatically adjust SCS control parameters to respond to changes in cardiac rhythm such as changes associated with ischemia, arrhythmia or heart failure.
摘要翻译：提供了用于控制脊髓刺激（SCS）或其他形式的神经刺激的技术。使用SCS装置的引线感测远场心电信号，并且神经刺激使用一组可调节的SCS控制参数选择性地递送。代表心律的参数来源于远场心电信号。代表心律的参数与SCS控制参数相关，从而将神经刺激控制设置映射到心律参数。然后基于神经刺激控制设置对心律参数的映射来控制进一步的神经刺激的传递，以例如解决基于远场心脏信号检测的任何心血管疾病。以这种方式，提供闭环控制系统以自动调整SCS控制参数以响应心律的变化，例如与缺血，心律失常或心力衰竭相关的变化。

35. 发明申请

US20130035738A1 METHODS AND SYSTEMS FOR DETERMINING PACING PARAMETERS BASED ON REPOLARIZATION INDEX 审中-公开
标题翻译：基于复合指数确定PAC参数的方法和系统
公开(公告)号：US20130035738A1
公开(公告)日：2013-02-07
申请号：US13197665
申请日：2011-08-03
申请人： Edward Karst , Kyungmoo Ryu , Stuart Rosenberg , Allen Keel
发明人： Edward Karst , Kyungmoo Ryu , Stuart Rosenberg , Allen Keel
IPC分类号： A61N1/368
CPC分类号： A61N1/3684 , A61N1/36507
摘要： Methods and systems are provided for determining pacing parameters for an implantable medical device (IMD). The methods and systems provide electrodes in the right atrium (RA), right ventricle (RV) and left ventricle (LV). The methods and systems sense RV cardiac signals and LV cardiac signals at an RV electrode and an LV electrode, respectively, over multiple cardiac cycles, to collect global activation information. The methods and systems identify a T-wave in the LV cardiac signal. The methods and systems calculate a repolarization index based at least in part on a timing of the T-wave identified in the LV cardiac signal. The methods and systems set at least one pacing parameter based on the repolarization index, wherein the at least one pacing parameter that is set represents at least one of an AV delay, an inter-ventricular interval and an intra-ventricular interval. Optionally, the methods and systems may deliver an RV pacing stimulus at the RV electrode such that the LV cardiac signal sensed thereafter includes the RV pacing stimulus followed by a T-wave. The methods and systems determine a waveform metric such as at least one of a QT interval, T-wave duration, and T-wave amplitude, and utilize the waveform metric to determine as the repolarization index.
摘要翻译：提供了用于确定可植入医疗装置（IMD）的起搏参数的方法和系统。方法和系统在右心房（RA），右心室（RV）和左心室（LV）中提供电极。方法和系统分别在多个心动周期上检测RV电极和LV电极上的RV心脏信号和LV心脏信号，以收集全局激活信息。方法和系统识别LV心脏信号中的T波。所述方法和系统至少部分地基于在LV心脏信号中识别的T波的定时来计算复极化指数。方法和系统基于复极度指数设置至少一个起搏参数，其中设置的至少一个起搏参数表示AV延迟，心室间间隔和心室间间隔中的至少一个。任选地，方法和系统可以在RV电极处递送RV起搏刺激，使得之后感测的LV心脏信号包括后跟T波的RV起搏刺激。方法和系统确定诸如QT间期，T波持续时间和T波幅度中的至少一个的波形度量，并且利用波形度量来确定复极化指数。

36. 发明授权

US08874213B2 System and method for monitoring diastolic function using an implantable medical device 有权
标题翻译：使用可植入医疗装置监测舒张功能的系统和方法
公开(公告)号：US08874213B2
公开(公告)日：2014-10-28
申请号：US13601569
申请日：2012-08-31
申请人： Allen Keel , Steve Koh , Taraneh Ghaffari Farazi
发明人： Allen Keel , Steve Koh , Taraneh Ghaffari Farazi
IPC分类号： A61N1/362 , A61N1/37 , A61N1/368 , A61N1/365
CPC分类号： A61N1/3702 , A61N1/3627 , A61N1/36507 , A61N1/368 , A61N1/3712
摘要： Diastolic function is monitored within a patient using a pacemaker or other implantable medical device. In one example, the implantable device uses morphological parameters derived from the T-wave evoked response waveform as proxies for ventricular relaxation rate and ventricular compliance. In particular, the magnitude of the peak of the T-wave evoked response is employed as a proxy for ventricular compliance. The maximum slew rate of the T-wave evoked response following its peak is employed as a proxy for ventricular relaxation. A metric is derived from these proxy values to represent diastolic function. The metric is tracked over time to evaluate changes in diastolic function. In other examples, specific values for ventricular compliance and ventricular relaxation are derived for the patient based on the T-wave evoked response parameters.
摘要翻译：使用起搏器或其他可植入医疗器械在患者体内监测舒张功能。在一个示例中，可植入装置使用从T波诱发反应波形导出的形态参数作为心室松弛率和心室顺应性的代理。特别地，T波诱发反应的峰值的大小被用作心室顺应性的代表。其峰值后的T波诱发反应的最大压摆率被用作心室松弛的代用品。来自这些代理值的度量来表示舒张功能。随着时间的推移跟踪度量以评估舒张功能的变化。在其他实例中，基于T波诱发反应参数为患者导出心室顺应性和心室松弛的具体值。

37. 发明授权

US08798765B2 Determination of cardiac resynchronization therapy settings 有权
标题翻译：心脏再同步治疗设置的测定
公开(公告)号：US08798765B2
公开(公告)日：2014-08-05
申请号：US13471167
申请日：2012-05-14
申请人： Kjell Noren , Anders Bjorling , Tomas Svensson , Sven-Erik Hedberg , Allen Keel , Stuart Rosenberg , Kyungmoo Ryu
发明人： Kjell Noren , Anders Bjorling , Tomas Svensson , Sven-Erik Hedberg , Allen Keel , Stuart Rosenberg , Kyungmoo Ryu
IPC分类号： A61N1/365 , A61N1/372 , A61N1/368
CPC分类号： A61N1/36507 , A61N1/3682 , A61N1/3684 , A61N1/37252
摘要： CRT settings for an implantable medical device are determined by applying pacing pulses to heart chambers of a scheme of different combinations of interchamber delays. A respective width parameter value representing an R or P wave width is determined for each such delay combination based on an ECG representing signal and the width parameter values are employed to estimate a parametric model defining the width parameter as a function of interchamber delays. Candidate interchamber delays that minimize the width parameter are determined from the parametric model and employed to determine optimal CRT settings. The technique provides an efficient way of finding optimal CRT settings when multiple pacing sites are available in a heart chamber.
摘要翻译：用于可植入医疗装置的CRT设置通过将不同组合的车间延迟的方案应用于心室来进行起搏脉冲来确定。基于ECG表示信号为每个这样的延迟组合确定表示R或P波宽的相应宽度参数值，并且使用宽度参数值来估计定义作为间歇延迟的函数的宽度参数的参数模型。从参数模型中确定最小化宽度参数的候选车间延迟，并用于确定最佳CRT设置。该技术提供了一种在心室中可用多个起搏部位时可以找到最佳CRT设置的有效方式。

38. 发明申请

US20110098770A1 SYSTEMS AND METHODS FOR OPTIMIZING MULTI-SITE LEFT VENTRICULAR PACING BASED ON INTERELECTRODE CONDUCTION DELAYS 有权
标题翻译：基于电介质导通延迟优化多位置左心室的系统和方法
公开(公告)号：US20110098770A1
公开(公告)日：2011-04-28
申请号：US12607817
申请日：2009-10-28
申请人： Kyungmoo Ryu , Stuart Rosenberg , Allen Keel
发明人： Kyungmoo Ryu , Stuart Rosenberg , Allen Keel
IPC分类号： A61N1/368 , A61N1/365
CPC分类号： A61N1/3627 , A61N1/368 , A61N1/3684
摘要： Techniques are provided for use with an implantable cardiac stimulation device equipped for multi-site left ventricular (MSLV) pacing using a multi-pole LV lead. In one example, MSLV interelectrode conduction delays are determined among the electrodes of the multi-pole LV lead. MSLV interelectrode pacing delays are then set based on the MSLV interelectrode conduction delays for use in delivering MSLV pacing. To this end, various criteria are exploited for determining optimal values for the pacing delays based on the interelectrode conduction delays. MSLV pacing is then controlled using the specified MSLV interelectrode pacing delays. In some examples, the optimization procedure is performed by the implantable device itself. In other examples, the procedure is performed by an external programmer device. In such an embodiment, the external device determines optimal MSLV interelectrode pacing delays and then transmits programming commands to the implantable device to program the device to use the pacing delays.
摘要翻译：提供技术用于使用多极LV引线配备用于多位点左心室（MSLV）起搏的可植入心脏刺激装置。在一个示例中，在多极LV引线的电极之间确定MSLV电极间导电延迟。然后根据MSLV电极间传导延迟来设置MSLV电极间起搏延迟，以用于传递MSLV起搏。为此，利用各种标准来确定基于电极间传导延迟的起搏延迟的最佳值。然后使用指定的MSLV电极间起搏延迟来控制MSLV起搏。在一些示例中，优化过程由可植入装置本身执行。在其他示例中，该过程由外部编程器设备执行。在这样的实施例中，外部设备确定最佳MSLV电极间起搏延迟，然后将编程命令发送到可植入设备，以对设备进行编程以使用起搏延迟。

39. 发明申请

US20080144959A1 Method and apparatus for pre-processing scans as a preparation for segmenting the same 有权
标题翻译：用于预处理扫描的方法和装置作为分割扫描的准备
公开(公告)号：US20080144959A1
公开(公告)日：2008-06-19
申请号：US11488802
申请日：2006-07-18
申请人： Matthias Rasch , Allen Keel , Christine H. Lorenz
发明人： Matthias Rasch , Allen Keel , Christine H. Lorenz
IPC分类号： G06K9/40
CPC分类号： G06T5/004
摘要： A computer-implemented method for pre-processing image data of a three-dimensional volume includes providing the image data of a vessel, applying a super-sampling filter to the image data to generate super-sampled image data having an increased resolution as compared to the image data, applying an unsharp masking filter to the super-sampled image data for increasing contrast of an edge of the vessel, applying a de-noising filer for removing noise surrounding the edge after applying the unsharp masking filter, and storing the image data after applying the de-noising filter thereto.
摘要翻译：用于预处理三维体积图像数据的计算机实现方法包括提供容器的图像数据，对图像数据应用超采样滤波器以产生具有增加的分辨率的超采样图像数据，与将所述图像数据应用于所述超采样图像数据，以增加所述容器的边缘的对比度;对所述图像数据应用所述图像数据之后，应用去噪滤光器以除去所述边缘周围的噪声;以及存储所述图像数据在其上应用去噪滤波器之后。

40. 发明申请

US20120330371A1 SYSTEM AND METHOD FOR MONITORING DIASTOLIC FUNCTION USING AN IMPLANTABLE MEDICAL DEVICE 有权
标题翻译：使用可植入医疗装置监测脱脂功能的系统和方法
公开(公告)号：US20120330371A1
公开(公告)日：2012-12-27
申请号：US13601569
申请日：2012-08-31
申请人： Allen Keel , Steve Koh , Taraneh Ghaffari Farazi
发明人： Allen Keel , Steve Koh , Taraneh Ghaffari Farazi
IPC分类号： A61N1/365
CPC分类号： A61N1/3702 , A61N1/3627 , A61N1/36507 , A61N1/368 , A61N1/3712
摘要： Diastolic function is monitored within a patient using a pacemaker or other implantable medical device. In one example, the implantable device uses morphological parameters derived from the T-wave evoked response waveform as proxies for ventricular relaxation rate and ventricular compliance. In particular, the magnitude of the peak of the T-wave evoked response is employed as a proxy for ventricular compliance. The maximum slew rate of the T-wave evoked response following its peak is employed as a proxy for ventricular relaxation. A metric is derived from these proxy values to represent diastolic function. The metric is tracked over time to evaluate changes in diastolic function. In other examples, specific values for ventricular compliance and ventricular relaxation are derived for the patient based on the T-wave evoked response parameters.
摘要翻译：使用起搏器或其他可植入医疗器械在患者体内监测舒张功能。在一个示例中，可植入装置使用从T波诱发反应波形导出的形态参数作为心室松弛率和心室顺应性的代理。特别地，T波诱发反应的峰值的大小被用作心室顺应性的代表。其峰值后的T波诱发反应的最大压摆率被用作心室松弛的代用品。来自这些代理值的度量来表示舒张功能。随着时间的推移跟踪度量以评估舒张功能的变化。在其他实例中，基于T波诱发反应参数为患者导出心室顺应性和心室松弛的具体值。

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式