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31. 发明授权

US08476253B2 Amide derivative 失效
标题翻译：酰胺衍生物
公开(公告)号：US08476253B2
公开(公告)日：2013-07-02
申请号：US13234514
申请日：2011-09-16
申请人： Takuya Ikeda , Takanori Yamazaki , Hiroshi Tsuchida
发明人： Takuya Ikeda , Takanori Yamazaki , Hiroshi Tsuchida
IPC分类号： C07D401/04 , A61K31/438
CPC分类号： C07D413/14 , C07D417/14
摘要： Compounds or pharmacologically acceptable salts thereof are provided. In various embodiments the compounds have an antagonistic effect on a neurokinin NK1 receptor, a neurokinin NK2 receptor, and a muscarine M3 receptor. The compounds are useful as therapeutic agents for bronchial asthma, chronic obstructive pulmonary disease, or the like.
摘要翻译：提供化合物或其药理学上可接受的盐。在各种实施方案中，化合物对神经激肽NK1受体，神经激肽NK2受体和毒蕈碱M3受体具有拮抗作用。这些化合物可用作支气管哮喘，慢性阻塞性肺病等的治疗剂。

32. 发明授权

US08270116B2 Magnetic disk drive and magnetic head slider with stabilized flying 失效
标题翻译：磁盘驱动器和磁头滑块具有稳定的飞行
公开(公告)号：US08270116B2
公开(公告)日：2012-09-18
申请号：US11522117
申请日：2006-09-14
申请人： Yuki Shimizu , Junguo Xu , Jianhua Li , Takanori Yamazaki
发明人： Yuki Shimizu , Junguo Xu , Jianhua Li , Takanori Yamazaki
IPC分类号： G11B5/60
CPC分类号： G11B5/6005
摘要： A magnetic disk drive includes a magnetic recording medium and a magnetic head slider adapted to fly over a surface of a magnetic recording medium and read or write information. The magnetic head slider includes a slider air bearing surface and a magnetic transducer. The slider air bearing surface includes a front pad having front rail surfaces and front step bearing surfaces, a rear pad having a rear rail surface and a rear step bearing surface, and a negative-pressure groove interposed between the front pad and the rear pad. A vibration suppressing groove is formed in the rear rail surface so as to be deeper than the rear rail surface and to be closed at its periphery. The vibration suppressing groove quickly damps out translational and pitching vibrations in the flying height direction of the magnetic head slider while stabilizing its flying.
摘要翻译：磁盘驱动器包括磁记录介质和适于在磁记录介质的表面上飞越并读取或写入信息的磁头滑块。磁头滑块包括滑块空气支承表面和磁换能器。滑块空气轴承表面包括具有前导轨表面和前阶梯支承表面的前垫，具有后轨表面和后台阶支承表面的后垫，以及插入在前垫和后垫之间的负压槽。在后轨面上形成振动抑制槽，使其比后轨面更深，并在其周边封闭。振动抑制槽在稳定其飞行的同时快速地减小磁头滑块的飞行高度方向上的平移和俯仰振动。

33. 发明申请

US20120071467A1 AMIDE DERIVATIVE 失效
公开(公告)号：US20120071467A1
公开(公告)日：2012-03-22
申请号：US13234514
申请日：2011-09-16
申请人： Takuya Ikeda , Takanori Yamazaki , Hiroshi Tsuchida
发明人： Takuya Ikeda , Takanori Yamazaki , Hiroshi Tsuchida
IPC分类号： A61K31/551 , C07D417/14 , A61K31/4545 , A61K31/501 , A61K31/506 , A61K31/5377 , A61K31/496 , A61P11/00 , A61P11/14 , A61P11/06 , A61P29/00 , A61P1/04 , A61P1/08 , A61P35/00 , A61P25/08 , A61P25/24 , A61P25/22 , A61P25/16 , C07D413/14
CPC分类号： C07D413/14 , C07D417/14
摘要： Compounds or pharmacologically acceptable salts thereof are provided. In various embodiments the compounds have an antagonistic effect on a neurokinin NK1 receptor, a neurokinin NK2 receptor, and a muscarine M3 receptor. The compounds are useful as therapeutic agents for bronchial asthma, chronic obstructive pulmonary disease, or the like.
摘要翻译：提供化合物或其药理学上可接受的盐。在各种实施方案中，化合物对神经激肽NK1受体，神经激肽NK2受体和毒蕈碱M3受体具有拮抗作用。这些化合物可用作支气管哮喘，慢性阻塞性肺病等的治疗剂。

34. 发明授权

US08105540B2 Method of treating polymer compound and treatment system for the same 失效
标题翻译：处理高分子化合物和处理系统的方法相同
公开(公告)号：US08105540B2
公开(公告)日：2012-01-31
申请号：US12821788
申请日：2010-06-23
申请人： Toshiharu Goto , Takanori Yamazaki , Yoshihiko Iwamoto , Jun Kakizaki
发明人： Toshiharu Goto , Takanori Yamazaki , Yoshihiko Iwamoto , Jun Kakizaki
IPC分类号： B01J19/18 , B01J19/00 , B01J19/20 , B28B17/00 , B29B13/00 , B29C47/92 , B29C47/38 , B29C47/78
CPC分类号： B29C47/50 , B29B17/02 , B29B17/04 , B29B2017/0293 , B29B2017/046 , B29C47/0004 , B29C47/0011 , B29C47/0014 , B29C47/0066 , B29C47/366 , B29C47/822 , B29C47/8815 , B29C47/92 , B29C2947/92019 , B29C2947/92104 , B29C2947/924 , B29C2947/92466 , B29C2947/92514 , B29C2947/926 , B29C2947/92704 , B29C2947/92895 , B29C2947/92961 , B29K2023/06 , C08J11/08 , Y02W30/622 , Y02W30/625 , Y02W30/701
摘要： A method of treating a polymer compound has the steps of: mixing and agitating the polymer compound and a chemical agent in an extruder while controlling the inside of the extruder to be kept at a high temperature and a high pressure to have a reaction mixture containing a polymer treated product; supplying the reaction mixture continuously into a high-pressure container disposed following the extruder and retaining the reaction mixture at the high temperature and high pressure for a predetermined time; then supplying the reaction mixture continuously to a chemical agent separator to separate the polymer treated product; and supplying the separated polymer treated product continuously to a molding means to form it into a molded material.
摘要翻译：处理高分子化合物的方法具有以下步骤：在挤出机内混合搅拌高分子化合物和化学试剂，同时控制挤出机的内部保持在高温和高压下，使含有聚合物处理产品; 将反应混合物连续地供入设置在挤出机后面的高压容器中，并将反应混合物保持在高温高压下一段预定时间; 然后将反应混合物连续供给到化学试剂分离器以分离聚合物处理产物; 并将分离的聚合物处理产物连续地供给到模制装置中以将其形成为模制材料。

35. 发明申请

US20050283006A1 Heteroaryl-substituted pyrrole derivatives, their preparation and their therapeutic uses 审中-公开
标题翻译：杂芳基取代的吡咯衍生物，其制备及其治疗用途
公开(公告)号：US20050283006A1
公开(公告)日：2005-12-22
申请号：US10411061
申请日：2003-04-10
申请人： Tomio Kimura , Kazumasa Aoki , Akira Nakao , Shigeru Ushiyama , Takaichi Shimozato , Nobuyuki Ohkawa , Takayoshi Nagasaki , Takanori Yamazaki
发明人： Tomio Kimura , Kazumasa Aoki , Akira Nakao , Shigeru Ushiyama , Takaichi Shimozato , Nobuyuki Ohkawa , Takayoshi Nagasaki , Takanori Yamazaki
IPC分类号： C07D401/04 , C07D401/14 , C07D451/02 , C07D453/02 , C07D455/02 , C07D471/04 , C07D487/04 , C07D491/20 , C07D41/14 , C07D43/02
CPC分类号： C07D451/02 , C07D401/04 , C07D401/14 , C07D453/02 , C07D455/02 , C07D471/04 , C07D487/04
摘要： Compounds having activity against production of inflammatory cytokines of formula (I)′: A′ is pyrrole; R1′ is aryl or heteroaryl; R2′ is heteroaryl having at least one nitrogen atom; R3′ is (IIa)′, (IIb)′ or (IIc)′: m′ is 1 or 2; one of D′ and E′ is nitrogen and the other is >C(R5′)—, R5′ is hydrogen, Substituent α′ or Substituent β′; B′ is nitrogen-containing 4- to 7-membered heterocyclic; R4′ is 1 to 3 substituents from Substituent α′, Substituent β′ and Substituent γ′; R1′ and R3′ are bonded to two atoms of the pyrrole adjacent to the pyrrole atom bonded to R2′; Substituent α′: hydroxyl, nitro, cyano, halogen, alkoxy, halogeno alkoxy, alkylthio, halogeno alkylthio or —NRa′Rb′; Ra′ and Rb′ are hydrogen, alkyl, alkenyl, alkynyl, aralkyl or alkylsulfonyl, or Ra′ and Rb′ with the nitrogen atom form a heterocyclyl; Substituent β′: alkyl, alkenyl, alkynyl, aralkyl or cycloalkyl; Substituent γ′: oxo, hydroxyimino, alkoxyimino, alkylene, alkylenedioxy, alkylsulfinyl, alkylsulfonyl, aryl, aryloxy, alkylidenyl or aralkylidenyl.
摘要翻译：具有抗式产生式（I）的炎性细胞因子的化合物的化合物：A'是吡咯; R 1是芳基或杂芳基; R 2是具有至少一个氮原子的杂芳基; （IIa）'，（IIb）'或（IIc）'：m'为1或2; D'和E'之一是氮，另一个是> C（R 5'） - ，R 5'是氢，取代基α'或取代基β'; B'是含氮的4-至7-元杂环; R 4'是1至3个取代基α'，取代基β'和取代基γ'的取代基; R 1'和R 3'连接到与R 2'连接的吡咯原子相邻的吡咯的两个原子上; 取代基α'：羟基，硝基，氰基，卤素，烷氧基，卤代烷氧基，烷硫基，卤代烷硫基或-NR a R b b。 R a，O和R b'是氢，烷基，烯基，炔基，芳烷基或烷基磺酰基，或者R a'和R“ b'与氮原子形成杂环基; 取代基β'：烷基，烯基，炔基，芳烷基或环烷基; 取代基γ'：氧代，羟基亚氨基，烷氧基亚氨基，亚烷基，亚烷基二氧基，烷基亚磺酰基，烷基磺酰基，芳基，芳氧基，亚烷基或芳烷基。

36. 发明授权

US08569628B2 Insulated wire 有权
标题翻译：绝缘电线
公开(公告)号：US08569628B2
公开(公告)日：2013-10-29
申请号：US12870329
申请日：2010-08-27
申请人： Tomiya Abe , Takanori Yamazaki , Kiyoshi Watanabe , Hideyuki Kikuchi , Takahiko Hanada , Daisuke Hino
发明人： Tomiya Abe , Takanori Yamazaki , Kiyoshi Watanabe , Hideyuki Kikuchi , Takahiko Hanada , Daisuke Hino
IPC分类号： H01B7/00
CPC分类号： H01B3/301 , H01B3/305 , H01B3/441 , H01B3/445
摘要： There is provided an insulated wire having an insulation film composed of a plurality of layers provided on a conductor, in which: the insulation film includes a first film layer and a second film layer; the first film layer is made of a first resin composition formed by graft-polymerizing a graft compound with an ethylene-tetrafluoroethylene copolymer and is provided on a circumference of the conductor; and the second film layer is made of a second resin composition being a polymer alloy made of a polyphenylene sulfide resin and a polyamide resin, or being a polymer alloy made of a polyether ether ketone resin and a polyamide resin and is provided on a circumference of the first film layer.
摘要翻译：提供了一种绝缘线，其具有由设置在导体上的多个层构成的绝缘膜，其中：所述绝缘膜包括第一膜层和第二膜层; 第一膜层由通过接枝聚合接枝化合物与乙烯 - 四氟乙烯共聚物形成的第一树脂组合物制成，并且设置在导体的圆周上; 并且第二膜层由作为由聚苯硫醚树脂和聚酰胺树脂制成的聚合物合金的第二树脂组合物或由聚醚醚酮树脂和聚酰胺树脂制成的聚合物合金制成，并且设置在第一个电影层。

37. 发明申请

US20120329791A1 Substituted Imidazopyridinyl-Aminopyridine Compounds 有权
标题翻译：取代的咪唑并吡啶基 - 氨基吡啶化合物
公开(公告)号：US20120329791A1
公开(公告)日：2012-12-27
申请号：US13529459
申请日：2012-06-21
申请人： Mark A. Ashwell , Chris Brassard , Anton Filikov , Jason Hill , Steffi Koerner , Jean-Marc Lapierre , Yanbin Liu , Nivedita Namdev , Robert Nicewonger , Rocio Palma , Manish Tandon , David Vensel , Akihisa Matsuda , Shin Iimura , Kenichi Yoshida , Takanori Yamazaki , Takahiro Kitamura , Takeshi Isoyama
发明人： Mark A. Ashwell , Chris Brassard , Anton Filikov , Jason Hill , Steffi Koerner , Jean-Marc Lapierre , Yanbin Liu , Nivedita Namdev , Robert Nicewonger , Rocio Palma , Manish Tandon , David Vensel , Akihisa Matsuda , Shin Iimura , Kenichi Yoshida , Takanori Yamazaki , Takahiro Kitamura , Takeshi Isoyama
IPC分类号： C07D471/04 , A61K31/5377 , A61P35/04 , A61K31/537 , C07D498/08 , A61K31/4375 , A61K31/496
CPC分类号： C07D471/04 , C07D451/02 , C07D491/08 , C07D498/08
摘要： The present invention relates to substituted imidazopyridinyl-aminopyridine compounds and methods of synthesizing these compounds. The present invention also relates to pharmaceutical compositions containing substituted imidazopyridinyl-aminopyridine compounds and methods of treating cell proliferative disorders, such as cancer, by administering these compounds and pharmaceutical compositions to subjects in need thereof.
摘要翻译：本发明涉及取代的咪唑并吡啶基 - 氨基吡啶化合物和合成这些化合物的方法。本发明还涉及含有取代的咪唑并吡啶基 - 氨基吡啶化合物的药物组合物和通过将这些化合物和药物组合物施用于有需要的受试者来治疗细胞增殖性疾病如癌症的方法。

38. 发明授权

US07767124B2 Method of treating polymer compound and treatment system for the same 有权
标题翻译：处理高分子化合物和处理系统的方法相同
公开(公告)号：US07767124B2
公开(公告)日：2010-08-03
申请号：US11095657
申请日：2005-04-01
申请人： Toshiharu Goto , Takanori Yamazaki , Yoshihiko Iwamoto , Jun Kakizaki
发明人： Toshiharu Goto , Takanori Yamazaki , Yoshihiko Iwamoto , Jun Kakizaki
IPC分类号： B01D3/00 , B01J3/02 , B29C47/36 , B29C47/78
CPC分类号： B29C47/50 , B29B17/02 , B29B17/04 , B29B2017/0293 , B29B2017/046 , B29C47/0004 , B29C47/0011 , B29C47/0014 , B29C47/0066 , B29C47/366 , B29C47/822 , B29C47/8815 , B29C47/92 , B29C2947/92019 , B29C2947/92104 , B29C2947/924 , B29C2947/92466 , B29C2947/92514 , B29C2947/926 , B29C2947/92704 , B29C2947/92895 , B29C2947/92961 , B29K2023/06 , C08J11/08 , Y02W30/622 , Y02W30/625 , Y02W30/701
摘要： A method of treating a polymer compound has the steps of: mixing and agitating the polymer compound and a chemical agent in an extruder while controlling the inside of the extruder to be kept at a high temperature and a high pressure to have a reaction mixture containing a polymer treated product; supplying the reaction mixture continuously into a high-pressure container disposed following the extruder and retaining the reaction mixture at the high temperature and high pressure for a predetermined time; then supplying the reaction mixture continuously to a chemical agent separator to separate the polymer treated product; and supplying the separated polymer treated product continuously to a molding means to form it into a molded material.
摘要翻译：处理高分子化合物的方法具有以下步骤：在挤出机内混合搅拌高分子化合物和化学试剂，同时控制挤出机的内部保持在高温和高压下，使含有聚合物处理产品; 将反应混合物连续地供入设置在挤出机后面的高压容器中，并将反应混合物保持在高温高压下一段预定时间; 然后将反应混合物连续供给到化学试剂分离器以分离聚合物处理产物; 并将分离的聚合物处理产物连续地供给到模制装置中以将其形成为模制材料。

39. 发明申请

US20050009935A1 Method and instrument of polymer processing treatment 有权
标题翻译：聚合物加工处理方法与仪器
公开(公告)号：US20050009935A1
公开(公告)日：2005-01-13
申请号：US10886634
申请日：2004-07-09
申请人： Masaaki Mukaide , Toshiharu Goto , Takanori Yamazaki , Yoshihiko Iwamoto , Jun Kakizaki
发明人： Masaaki Mukaide , Toshiharu Goto , Takanori Yamazaki , Yoshihiko Iwamoto , Jun Kakizaki
IPC分类号： C08J11/10 , C08J11/04 , C08J11/24
CPC分类号： C08J11/24 , C08J11/10 , Y02W30/702 , Y02W30/706
摘要： The object of the present invention resides in providing a method and instrument of polymer processing treatment, wherein a sudden pressure change due to expansion by gasification of a reactant when it is exhausted from a reacting extruder is given in a little amount to a molding machine for a treated substance, and a change in the amount of the material supplied to the molding machine and a variation in molding are little, and hence continuous and uniform molding is possible. That is, the method of the present invention resides in a method of polymer processing treatment, which includes the steps of: reacting a polymer with a reactant under mixing and stirring at a high temperature and a high pressure in the inside of a reacting extruder to produce the treated substance; introducing said treated substance and a remaining reactant into a reactant-separation tank to separate the treated substance and the reactant; and molding the separated treated substance.
摘要翻译：本发明的目的在于提供一种聚合物加工处理的方法和仪器，其中当反应物从反应挤出机排出时，由反应物的气化引起的膨胀引起的突然的压力变化少量给予成型机被处理物质和供给到成型机的材料量的变化和成型变化很小，因此可以连续均匀地成型。也就是说，本发明的方法在于聚合物加工处理方法，其包括以下步骤：在反应挤出机内部的高温和高压下在混合和搅拌下使聚合物与反应物反应，生产经处理的物质; 将所述处理的物质和剩余的反应物引入反应物分离罐中以分离处理的物质和反应物; 并模制分离的处理物质。

40. 发明授权

US08995776B2 Image filter device, decoding apparatus, encoding apparatus, and data structure 有权
标题翻译：图像滤波装置，解码装置，编码装置和数据结构
公开(公告)号：US08995776B2
公开(公告)日：2015-03-31
申请号：US13704169
申请日：2011-06-02
申请人： Tomohiro Ikai , Tomoyuki Yamamoto , Takanori Yamazaki
发明人： Tomohiro Ikai , Tomoyuki Yamamoto , Takanori Yamazaki
IPC分类号： G06K9/40 , G06T5/00 , G06T9/00 , H04N19/176 , H04N19/70 , H04N19/593 , H04N19/117 , H04N19/14 , H04N19/17 , H04N19/82
CPC分类号： G06T5/001 , G06T9/004 , H04N19/117 , H04N19/14 , H04N19/17 , H04N19/176 , H04N19/593 , H04N19/70 , H04N19/82
摘要： An adaptive filter includes: an edge direction detection section which discriminates directionality of an input image in each of a plurality of unit regions constituting the input image; a region classification section which classifies the each of the plurality of unit regions into one of a plurality of unit region groups in accordance with to which of a plurality of predetermined groups the directionality of the input image in the each of the plurality of unit regions belongs, the directionality having been discriminated by the edge direction detection section; and a filter process section which calculates a pixel value of the each pixel of an output image by use of a filter coefficient group optimized for a unit region group to which a unit region including the each pixel belongs.
摘要翻译：自适应滤波器包括：边缘方向检测部，其识别构成输入图像的多个单位区域中的每一个中的输入图像的方向性; 区域分类部，根据多个单位区域中的每一个所属的输入图像的方向性，将多个单位区域中的每一个分类为多个单位区域组中的一个，所述方向性被所述边缘方向检测部所区分; 以及滤波处理部，其通过使用针对包括每个像素的单位区域属于的单位区域群优化的滤波器系数组来计算输出图像的每个像素的像素值。

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