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31. 发明授权

US08778938B2 Hepatitis C virus inhibitors 失效
标题翻译：丙型肝炎病毒抑制剂
公开(公告)号：US08778938B2
公开(公告)日：2014-07-15
申请号：US13152377
申请日：2011-06-03
申请人： Yao-Ling Qiu , Ce Wang , Hui Cao , Xiaowen Peng , Datong Tang , Yat Sun Or
发明人： Yao-Ling Qiu , Ce Wang , Hui Cao , Xiaowen Peng , Datong Tang , Yat Sun Or
IPC分类号： A61K31/397 , A61K31/5377 , A61K31/495 , A61K31/506 , A61K31/443 , A61K31/4525 , A61K31/47 , A61K31/41 , A61K31/4178 , A61K31/4196 , A61K31/422 , A61K31/42 , A61K31/4245 , A61K31/427 , A61K31/428 , C07D273/01 , C07D239/24 , C07D241/04 , C07D221/20 , C07D277/60 , C07D277/20 , C07D263/02 , C07D263/30 , C07D261/20 , C07D257/02 , C07D233/54
CPC分类号： A61K31/4178 , A61K31/422 , A61K31/427 , A61K31/4439 , A61K31/496 , A61K31/5377 , A61K31/7056 , A61K38/21 , A61K45/06 , C12N2770/24211 , A61K2300/00
摘要： The present invention discloses compounds of Formula (I), or pharmaceutically acceptable salts, esters, or prodrugs thereof: which inhibit RNA-containing virus, particularly the Hepatitis C Virus (HCV). Consequently, the compounds of the present invention interfere with the life cycle of the Hepatitis C Virus and are also useful as antiviral agents. The present invention further relates to pharmaceutical compositions comprising the aforementioned compounds for administration to a subject suffering from HCV infection. The invention also relates to methods of treating an HCV infection in a subject by administering a pharmaceutical composition comprising the compounds of the present invention.
摘要翻译：本发明公开了式（I）化合物或其药学上可接受的盐，酯或前药：其抑制含RNA病毒，特别是丙型肝炎病毒（HCV）。因此，本发明的化合物干扰丙型肝炎病毒的生命周期，也可用作抗病毒剂。本发明还涉及药物组合物，其包含用于给患有HCV感染的受试者施用的上述化合物。本发明还涉及通过施用包含本发明化合物的药物组合物来治疗受试者的HCV感染的方法。

32. 发明申请

US20140111671A1 Systems and Methods for Imaging Using a Random Laser 审中-公开
标题翻译：使用随机激光成像的系统和方法
公开(公告)号：US20140111671A1
公开(公告)日：2014-04-24
申请号：US14110937
申请日：2012-04-16
申请人： Hui Cao , Brandon Redding , Michael Choma
发明人： Hui Cao , Brandon Redding , Michael Choma
IPC分类号： H04N5/235 , H01S3/10
摘要： Systems and methods are provided for imaging using complex lasers. In general, a complex laser may be used as an electromagnetic source for an imaging application. The use of a lower spatial coherence configured complex laser in imaging applications may advantageously mitigate coherent artifacts in imaging such as cross-talk and speckle and improve overall image quality. Imaging applications where a complex laser may be useful include both incoherent imaging applications, such as digital light projectors and traditional microscopy, and coherent imaging applications, such as optical coherence tomography (OCT) and holography. The systems and methods provided also enable controlling the degree of spatial coherence of a complex laser.
摘要翻译：提供了使用复合激光成像的系统和方法。通常，复合激光器可以用作成像应用的电磁源。在成像应用中使用配置复杂激光的较低的空间相干性可以有利地减轻成像中的相干伪影，例如串扰和散斑，并提高整体图像质量。复合激光器可能有用的成像应用包括非相干成像应用，如数字光投影仪和传统显微镜，以及相干成像应用，如光学相干断层扫描（OCT）和全息术。所提供的系统和方法还能够控制复杂激光器的空间相干性程度。

33. 发明申请

US20140023732A1 USE OF A TRADITIONAL CHINESE MEDICINE COMBINATION IN PREPARATION OF ANTI-ENTEROVIRUS 71 DRUG 审中-公开
标题翻译：传统中医药组合在制备抗肠毒素71药物中的应用
公开(公告)号：US20140023732A1
公开(公告)日：2014-01-23
申请号：US13990920
申请日：2011-12-28
申请人： Hui Cao , Yi Guan , Yongqing Zeng , Desheng Tao
发明人： Hui Cao , Yi Guan , Yongqing Zeng , Desheng Tao
IPC分类号： A61K36/67 , A61K36/282 , A61K36/484 , A61K36/315
CPC分类号： A61K36/67 , A61K9/1623 , A61K36/11 , A61K36/19 , A61K36/232 , A61K36/282 , A61K36/315 , A61K36/355 , A61K36/484 , A61K36/489 , A61K36/78 , A61K36/88 , A61K36/896 , A61K2300/00
摘要： Disclosed is a use of a pharmaceutical composition in preparation of anti-enterovirus 71 agents.
摘要翻译：公开了药物组合物在制备抗肠道病毒71剂中的用途。

34. 发明申请

US20120300590A1 Clamp Type Ultrasonic Processor and Application thereof 有权
标题翻译：夹式超声波处理器及其应用
公开(公告)号：US20120300590A1
公开(公告)日：2012-11-29
申请号：US13576398
申请日：2010-11-01
申请人： Zhuosheng Yan , Jinxuan Yan , Zhuoli Yan , Zhizhong Yang , Qiang Ye , Hui Cao , Yanmiao He
发明人： Zhuosheng Yan , Jinxuan Yan , Zhuoli Yan , Zhizhong Yang , Qiang Ye , Hui Cao , Yanmiao He
IPC分类号： H04B1/03
CPC分类号： B22D1/00 , B22D27/20
摘要： A clamp type ultrasonic processor comprises a transducer assembly and a functional gripper. The transducer assembly comprises a transducer (1) and an amplitude transforming shaft (2) attached thereto. At least one transducer assembly is connected to the functional gripper. The functional gripper comprises an irradiation front line shaft-approximal block (3) and an irradiation front line tube-supporting block (4), and a functional gripper chamber (8) is provided in the functional gripper for accommodating an ultrasonic irradiation receiver. The irradiation front line shaft-approximal block (3) and the irradiation front line tube-supporting block (4) are connected to grip tightly the ultrasonic irradiation receiver to be irradiated. Irradiation front line shaft-approximal block (3) and/or the irradiation front line tube-supporting block (4) are connected to the amplitude transforming shaft (2). An application of the clamp type ultrasonic processor and its application in metal production are also provided.
摘要翻译：夹式超声波处理器包括换能器组件和功能夹持器。换能器组件包括连接到其上的换能器（1）和振幅变换轴（2）。至少一个换能器组件连接到功能夹持器。功能夹持器包括照射前线轴近似块（3）和照射前线管支撑块（4），功能夹持器（8）设置在功能夹持器中，用于容纳超声波照射接收器。照射前线轴近似块（3）和照射前线管支撑块（4）连接以紧紧地夹紧要照射的超声波照射接收器。照射前线轴近似块（3）和/或照射前线管支撑块（4）与振幅变换轴（2）连接。还提供了夹式超声波处理器的应用及其在金属生产中的应用。

35. 发明申请

US20120093951A1 TRADITIONAL CHINESE MEDICINE COMPOSITION FOR TREATING SWINE INFLUENZA, PREPARATION METHOD AND USE THEREOF 审中-公开
标题翻译：传统中医药组合物，用于治疗肝炎流行性感冒，其制备方法及其用途
公开(公告)号：US20120093951A1
公开(公告)日：2012-04-19
申请号：US13377862
申请日：2010-06-17
申请人： Desheng Tao , Yongging Zeng , Hui Cao , Yi Guan
发明人： Desheng Tao , Yongging Zeng , Hui Cao , Yi Guan
IPC分类号： A61K36/78 , A61K36/315 , A61K36/489 , A61K36/232 , A61K36/19 , A61P31/16 , A61K36/282 , A61K36/80 , A61K36/534 , A61K36/346 , A61K36/484 , A61K36/355 , A61K36/906
CPC分类号： A61K36/78 , A61K31/12 , A61K36/11 , A61K36/185 , A61K36/19 , A61K36/232 , A61K36/282 , A61K36/288 , A61K36/315 , A61K36/34 , A61K36/355 , A61K36/484 , A61K36/489 , A61K36/534 , A61K36/70 , A61K36/88 , A61K36/896 , A61K2300/00
摘要： The present invention relates to a traditional Chinese medicine composition for preventing and treating swine influenza, preparation method and use thereof. The said traditional Chinese medicine composition is made from Herba Houttuyniae 21.4 wt. %, Caulis Lonicerae Japonicae 17.9 wt. %, Radix Isatidis 14.3 wt. %, Rhizoma Dryopteris Crassirhizomatis 10.7%, Radix et Rhizoma Sophorae Tonkinensis 7.1 wt. %, Radix Angelicae Dahuricae 7.1 wt. %, Rhizoma Paridis 7.1 wt. %, Herba Artemisiae Annuae 7.1 wt. %, and Rhizoma Iridis Tectori 7.1 wt. %.
摘要翻译：本发明涉及一种预防和治疗猪流感的中药组合物及其制备方法及用途。所述中药组合物由鱼腥草21.4重量％％，金银花金银花17.9重量％％，石斛兰14.3重量％％，Rhizoma Dryopteris Crassirhizomatis 10.7％，Radix et Rhizoma Sophorae Tonkinensis 7.1 wt。％，当归甘草7.1重量％％，百日草7.1重量％％，蒿蒿7.1重量％％，枸杞子（Rhizoma Iridis Tectori）7.1重量％％。

36. 发明申请

US20110142798A1 HEPATITIS C VIRUS INHIBITORS 有权
公开(公告)号：US20110142798A1
公开(公告)日：2011-06-16
申请号：US12967486
申请日：2010-12-14
申请人： Yao-Ling Qiu , Ce Wang , Xiaowen Peng , Hui Cao , Lu Ying , Yat Sun Or
发明人： Yao-Ling Qiu , Ce Wang , Xiaowen Peng , Hui Cao , Lu Ying , Yat Sun Or
IPC分类号： A61K38/21 , C07D403/14 , A61K31/4184 , C07D401/14 , A61K31/4439 , A61K31/454 , C07D413/14 , A61K31/5377 , A61K31/496 , A61K31/439 , A61K31/7056 , A61P31/14 , C12N7/06
CPC分类号： C07D401/14 , A61K38/00 , C07D403/14 , C07D413/14
摘要： The present invention discloses compounds of Formula (I), or pharmaceutically acceptable salts, esters, or prodrugs thereof: which inhibit RNA-containing virus, particularly the hepatitis C virus (HCV). Consequently, the compounds of the present invention interfere with the life cycle of the hepatitis C virus and are also useful as antiviral agents. The present invention further relates to pharmaceutical compositions comprising the aforementioned compounds for administration to a subject suffering from HCV infection. The invention also relates to methods of treating an HCV infection in a subject by administering a pharmaceutical composition comprising the compounds of the present invention.

37. 发明申请

US20090314642A1 CARBON NANOTUBES BONDING ON METALLIC ELECTRODES 审中-公开
标题翻译：碳纳米管结合在金属电极上
公开(公告)号：US20090314642A1
公开(公告)日：2009-12-24
申请号：US12109936
申请日：2008-04-25
申请人： Zhiyin Gan , Sheng Liu , Qiang Lv , Xiaohui Song , Hui Cao , Han Yan
发明人： Zhiyin Gan , Sheng Liu , Qiang Lv , Xiaohui Song , Hui Cao , Han Yan
IPC分类号： C25B7/00
CPC分类号： H01L23/53276 , H01L2221/1094 , H01L2924/0002 , H01L2924/00
摘要： A method for large scale bonding carbon nanotubes on metallic electrodes is disclosed. The method includes that the wafer with a number of patterned electrodes deposited by CNTs via dielectrophoresis method is put onto the pedestal of our designed RF induction heating system. Then, the winding with alternating current induces scroll current on the surface of metallic electrodes due to skin effect. In this case, the current will generate Joule heat which could melt the surface metal of the electrodes. Finally, the CNTs will sink into the surface of the electrodes after short time heating. By varying the parameters of the RF source we can control the bonding process.
摘要翻译：公开了一种在金属电极上大规模结合碳纳米管的方法。该方法包括通过介电电泳方法将具有多个通过CNT沉积的图案化电极的晶片放置在我们设计的RF感应加热系统的基座上。然后，具有交替电流的绕组由于皮肤效应而在金属电极的表面上引起涡流电流。在这种情况下，电流将产生焦耳热，这可以熔化电极的表面金属。最后，在短时间加热后，CNT将沉入电极的表面。通过改变RF源的参数，我们可以控制粘合过程。

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