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31. 发明申请

US20070059260A1 Benzyl-1,3-thiazolidine-2,4-dione compounds for promoting and/or inducing and/or stimulating the pigmentation of keratin materials and/or for limiting their depigmentation and/or whitening 审中-公开
标题翻译：苄基-1,3-噻唑烷-2,4-二酮化合物，用于促进和/或诱导和/或刺激角蛋白材料的着色和/或限制其脱色和/或增白
公开(公告)号：US20070059260A1
公开(公告)日：2007-03-15
申请号：US11476054
申请日：2006-06-28
申请人： Christophe Boulle , Maria Dalko
发明人： Christophe Boulle , Maria Dalko
IPC分类号： A61K8/49
CPC分类号： A61K8/49 , A61Q5/065 , A61Q19/04
摘要： The benzyl-1,3-thiazolidine-2,4-dione compounds having the structural formula (I), or salt and/or solvate thereof: are useful active agents for promoting and/or inducing and/or stimulating the pigmentation of keratin materials and/or preventing and/or limiting the depigmentation and/or bleaching thereof, particularly of human head hair, beard hair, moustache hair, eyelashes and eyebrows, and advantageously are active agents for preventing and/or limiting the canities of human keratin fibers.
摘要翻译：具有结构式（I）的苄基-1,3-噻唑烷-2,4-二酮化合物或其盐和/或溶剂化物：用于促进和/或诱导和/或刺激角蛋白材料着色的有用的活性剂和/或预防和/或限制其脱色和/或漂白，特别是人头发，胡须头发，胡须头发，睫毛和眉毛的脱色和/或漂白，并且有利地是用于预防和/或限制人角蛋白纤维的阴茎的活性剂。

32. 发明授权

US07182949B2 Composition comprising vitamin C prepared during application, use of enzymes for forming vitamin C for topical use, and a cosmetic treatment method 失效
标题翻译：包含在施用期间制备的维生素C，用于形成用于局部使用的维生素C的酶的组合物和美容治疗方法
公开(公告)号：US07182949B2
公开(公告)日：2007-02-27
申请号：US10076418
申请日：2002-02-19
申请人： Maria Dalko , Rui Pereira
发明人： Maria Dalko , Rui Pereira
IPC分类号： A61K9/00 , A61K9/10 , A61K9/48 , A61K9/50 , A61K38/44 , A61K36/00 , A61K35/00
CPC分类号： A61K8/66 , A61K8/0204 , A61K8/11 , A61K8/60 , A61K8/676 , A61K2800/412 , A61K2800/88 , A61Q19/00 , A61Q19/02 , A61Q19/04
摘要： The invention concerns a composition for topical application for extemporaneous preparation, comprising ascorbic acid and a suitable support, the ascorbic acid being obtained by bringing at least one ascorbic acid precursor with the exception of its esters into contact with at least one enzyme that is capable of converting said precursor. It also concerns the use of one or more enzymes selected from L-galactono-1,4-lactone dehydrogenase, L-galactose dehydrogenase, L-sorbosone dehydrogenase, L-gulono-1,4-lactone oxidase and mixtures thereof, or of an extract comprising said enzyme, for the preparation of ascorbic acid for topical use, and a cosmetic method for treating the skin consisting of applying to the skin, either simultaneously or successively, at least one enzyme that can convert an ascorbic acid precursor into ascorbic acid, and at least one ascorbic acid precursor with the exception of its esters.
摘要翻译：本发明涉及用于临时制剂局部施用的组合物，其包含抗坏血酸和合适的载体，所述抗坏血酸是通过使至少一种抗坏血酸前体除了其酯与至少一种能够转化所述前体。还涉及使用一种或多种选自L-半乳糖内酰-1,4-内酯脱氢酶，L-半乳糖脱氢酶，L-山梨糖酮脱氢酶，L-古洛酮-1,4-内酯氧化酶及其混合物的酶，或包含所述酶的提取物，用于制备用于局部使用的抗坏血酸，以及用于治疗皮肤的美容方法，其包括同时或依次施用于皮肤，至少一种可将抗坏血酸前体转化成抗坏血酸的酶，和除了其酯之外的至少一种抗坏血酸前体。

33. 发明申请

US20060223763A1 C-glycoside compounds for stimulating the synthesis of glycosaminoglycans 有权
公开(公告)号：US20060223763A1
公开(公告)日：2006-10-05
申请号：US11373485
申请日：2006-03-13
申请人： Maria Dalko , Lionel Breton
发明人： Maria Dalko , Lionel Breton
IPC分类号： A61K31/7008 , A61K31/7024 , A61K31/70
CPC分类号： A61K8/602 , A61Q19/08 , C07H7/00
摘要： C-glycoside compounds are suited for stimulating the synthesis of glycosaminoglycans containing a D-glucosamine and/or N-acetyl-D-glucosamine residue, advantageously hyaluronic acid, and/or proteoglycans, advantageously proteoglycans containing hyaluronic acid, by fibroblasts and/or keratinocytes.

34. 发明申请

US20060211659A9 Novel compounds of the N-acylamino amide family, compositions comprising them and uses thereof 有权
标题翻译： N-酰氨基酰胺家族的新型化合物，包含它们的组合物及其用途
公开(公告)号：US20060211659A9
公开(公告)日：2006-09-21
申请号：US11102812
申请日：2005-04-11
申请人： Maria Dalko , Yann Mahe , Lionel Breton
发明人： Maria Dalko , Yann Mahe , Lionel Breton
IPC分类号： A61K31/66 , C07F9/02 , C07C235/66
CPC分类号： A61K8/44 , A61K8/69 , A61K38/00 , A61K2800/782 , A61Q5/00 , A61Q7/00 , A61Q19/08 , C07K5/06052 , C07K5/06191
摘要： The invention concerns novel compounds of the N-acylamino-amide family, compositions, in particular cosmetic or pharmaceutical, containing them, and their use for treating body or face skin ageing, whether chronobiologic or light-induced, and in particular skin ageing caused by decrease of skin elasticity and/or by collagen degradation in the structure of tissues.
摘要翻译：本发明涉及N-酰基氨基 - 酰胺家族的新化合物，包含它们的组合物，特别是化妆品或药物，以及它们用于治疗身体或面部皮肤老化，无论是时间生物学或光诱导的用途，特别是由降低皮肤弹性和/或通过组织结构中的胶原蛋白降解。

35. 发明申请

US20060167102A1 Compositions comprising cyclopentane derivatives and their use 审中-公开
标题翻译：包含环戊烷衍生物的组合物及其用途
公开(公告)号：US20060167102A1
公开(公告)日：2006-07-27
申请号：US11389166
申请日：2006-03-27
申请人： Jean-Luc Leveque , Maria Dalko , Christophe Boulle
发明人： Jean-Luc Leveque , Maria Dalko , Christophe Boulle
IPC分类号： A61K31/557
CPC分类号： A61K8/36 , A61K8/35 , A61K8/37 , A61K2800/28 , A61Q19/00 , A61Q19/08
摘要： Cosmetic or pharmaceutical compositions comprising compounds of formula (I) and the corresponding salts thereof: in which: R1 is a radical chosen from —COOR′, —CONR′R″, —CH2OR′, —COR′, —CH2R′, —SO2OR′, —PO3R′R″ and —NHR′, wherein R′ and R,″ which may be identical or different, are chosen from a hydrogen atom and saturated and unsaturated, linear, branched and cyclic hydrocarbon radicals comprising from 1 to 18 carbon atoms, which are optionally substituted by from 1 to 5 identical or different entities chosen from —OR′″, —OCOR′″, —SR′″, —SCOR′″, NR′″R″″, —NHCOR′″, halogen atoms, —CN, —COOR′″ and —COR′″, wherein R′″ and R″″, which may be identical or different, are chosen from a hydrogen atom, aryl radicals and saturated and unsaturated, linear and branched hydrocarbon radicals comprising from 1 to 4 carbon atoms; R2 is a radical chosen from linear, branched and cyclic hydrocarbon radicals comprising at least one unsaturation and comprising from 2 to 18 carbon atoms, which are optionally substituted by from 1 to 5 identical or different entities chosen from —OR′″, —OCOR′″, —SR′″, —SCOR′″, NR′″R″″, —NHCOR′″, halogen atoms, —CN, —COOR′″ and —COR′″, wherein R′″ and R″″, which may be identical or different, are chosen from a hydrogen atom, aryl radicals and saturated and unsaturated, linear and branched hydrocarbon radicals comprising from 1 to 4 carbon atoms as well as the use of these compounds, for example, to promote skin desquamation, to stimulate epidermal renewal and/or to combat the signs of skin ageing.
摘要翻译：包含式（I）化合物及其相应盐的化妆品或药物组合物：其中：R 1是选自-COOR'，-CONR'R“，-CH” 2 OR'，-COR'，-CH 2 R'，-SO 2 OR'，-PO 3 R' R“和-NHR'，其中可以相同或不同的R'和R”选自氢原子和包含1至18个碳原子的饱和和不饱和，直链，支链和环状烃基，其中任选地被1至5个相同或不同的选自-OR“，-OCOR”'，-SR“'，-SCOR”，NR“'R”'，-NHCOR “，卤素原子，-CN，-COOR”和-COR“，其中R”'和R“'可以相同或不同，选自氢原子，芳基和包含1至4个碳原子的饱和和不饱和的直链和支链烃基; R 2是选自包含至少一个不饱和键并包含2至18个碳原子的直链，支链和环状烃基的基团，其任选被1至5个相同或不同的实体取代，所述实体选自 -OR''，-OCOR''，-SR“'，-SCOR''，NR”'R“'， - NHCOR''，卤素原子，-CN，-COOR” '和-COR''，其中可以相同或不同的R“'和R”'选自氢原子，芳基和饱和和不饱和的直链和支链烃基，其包含1至 4个碳原子以及这些化合物的使用，例如促进皮肤脱屑，刺激表皮更新和/或抵抗皮肤老化的迹象。

36. 发明授权

US06548532B2 Indolecarboxylic compounds for treating seborrhea and complications thereof 失效
公开(公告)号：US06548532B2
公开(公告)日：2003-04-15
申请号：US10000293
申请日：2001-12-04
申请人： Maria Dalko , Jean-Baptiste Galey , Bruno Bernard
发明人： Maria Dalko , Jean-Baptiste Galey , Bruno Bernard
IPC分类号： A61K31405
CPC分类号： A61K8/492 , A61Q19/00 , A61Q19/008
摘要： Indolecarboxylic acid compounds and derivatives thereof are useful for treating seboarhea and the dermatitides associated therewith, especially acne and/or blackheads and/or comedones.

37. 发明授权

US10117816B2 Cosmetic process for treating human body odor using a 4-(3-ethoxy-4-hydroxyphenyl)alkyl ketone or 2-ethoxy-4-hydroxyalkylphenol compound 有权
公开(公告)号：US10117816B2
公开(公告)日：2018-11-06
申请号：US14007853
申请日：2012-03-29
申请人： Maria Dalko
发明人： Maria Dalko
IPC分类号： A61K8/35 , A61K8/34 , A61K8/02 , A61Q15/00
摘要： The present invention relates to a cosmetic process for treating human body odor, in particular underarm odor, which consists in applying to human keratin materials a composition containing, in a cosmetically acceptable medium, at least one 4-(3-ethoxy-4-hydroxyphenyl)alkyl ketone or 2-ethoxy-4-hydroxyalkylphenol compound of formula (I) below: in which: R represents a hydrogen atom, or a linear or branched, saturated or unsaturated (alkyl or alkenyl), C1-C18 hydrocarbon-based radical; R′ represents a linear or branched, saturated or unsaturated (alkyl or alkenyl), C1-C18 hydrocarbon-based radical, optionally substituted with a hydroxyl group; C—X represents C═O or CH—OH. The invention also relates to the cosmetic use of at least one compound of formula (I), as a deodorant active agent.

38. 发明授权

US09427604B2 Use of benzyloxy-ethylamine derivatives as a preservative, preservation method, and compositions 有权
标题翻译：使用苄氧基 - 乙胺衍生物作为防腐剂，保存方法和组合物
公开(公告)号：US09427604B2
公开(公告)日：2016-08-30
申请号：US13512518
申请日：2010-11-25
申请人： Roger Rozot , Maria Dalko
发明人： Roger Rozot , Maria Dalko
IPC分类号： A61Q17/00 , A61K8/41 , A61Q1/00 , A61Q5/00 , A61Q9/00 , A61Q19/10
CPC分类号： A61Q17/005 , A61K8/41 , A61K2800/524 , A61Q1/00 , A61Q5/00 , A61Q9/00 , A61Q19/10
摘要： The invention relates to the use of a compound of formula (I), or salts thereof, as a preserving agent, in particular in a cosmetic, dermatological or pharmaceutical composition: in which R1 and R2 represent H, methyl, ethyl, phenyl or benzyl. The invention also relates to a method of preserving a cosmetic, dermatological or pharmaceutical composition, consisting in incorporating said compound of formula (I) therein; and also to the compositions thus obtained.
摘要翻译：本发明涉及式（I）化合物或其盐作为防腐剂，特别是在化妆品，皮肤病学或药物组合物中的用途：其中R 1和R 2表示H，甲基，乙基，苯基或苄基。本发明还涉及一种保存化妆品，皮肤病学或药物组合物的方法，其包括在其中加入所述式（I）化合物; 以及由此获得的组合物。

39. 发明授权

US08722025B2 Cosmetic dermatological composition, cosmetic treatment method, and hyaluronic acid derivative 有权
标题翻译：化妆品皮肤病学组成，美容治疗方法和透明质酸衍生物
公开(公告)号：US08722025B2
公开(公告)日：2014-05-13
申请号：US13520426
申请日：2010-12-14
申请人： Sandrine Chodorowski-Kimmes , Maria Dalko
发明人： Sandrine Chodorowski-Kimmes , Maria Dalko
IPC分类号： A61K8/73 , A61Q3/00 , A61Q1/10 , A61Q9/04 , A61Q7/00 , A61Q5/02 , A61Q5/06 , A61Q1/00 , C08B37/08
CPC分类号： A61Q19/08 , A61K8/735 , C08B37/0072 , C08G18/6484 , C08G18/714
摘要： The invention relates to a cosmetic or dermatological composition comprising a hyaluronic acid derivative which comprises ureidopyrimidone units, to the said derivatives and to a cosmetic treatment method using them.
摘要翻译：本发明涉及一种化妆品或皮肤病学组合物，其包含含有脲基吡啶酮单元的透明质酸衍生物，所述衍生物和使用它们的美容治疗方法。

40. 发明申请

US20140050678A1 USE, AS ANTIDANDRUFF AGENT, OF (ETHOXYHYDROXYPHENYL) ALKYL KETONE OR ETHOXYHYDROXYALKYLPHENOL COMPOUNDS 有权
标题翻译：（乙氧基羟基苯甲酮）酮或乙氧基羟基羟基苯酚化合物作为抗转染剂使用
公开(公告)号：US20140050678A1
公开(公告)日：2014-02-20
申请号：US14007565
申请日：2012-03-30
申请人： Maria Dalko
发明人： Maria Dalko
IPC分类号： A61K8/35 , A61Q17/04 , A61Q5/00 , A61K8/34
CPC分类号： A61K8/35 , A61K8/347 , A61Q5/006 , A61Q17/04
摘要： The present invention relates to the use, as an antidandruff agent, of a compound of formula: in which: R1 represents a hydrogen atom or a hydrocarbon-based radical; R′ represents a C1-C18 hydrocarbon-based radical, optionally substituted with a hydroxyl group; C—X represents C═O or CH—OH.
摘要翻译：本发明涉及以下化合物作为去头屑剂的用途：其中：R1表示氢原子或烃基; R'表示任选被羟基取代的C 1 -C 18烃基; C-X表示C = O或CH-OH。

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