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31. 发明授权

US07108707B2 Hinged short cage for an embolic protection device 有权
公开(公告)号：US07108707B2
公开(公告)日：2006-09-19
申请号：US10600817
申请日：2003-06-20
申请人： Benjamin C. Huter , Kevin M. Magrini , John E. Papp
发明人： Benjamin C. Huter , Kevin M. Magrini , John E. Papp
IPC分类号： A61M29/00
CPC分类号： A61F2/013 , A61F2002/015 , A61F2002/018 , A61F2230/0006 , A61F2230/008
摘要： A filtering device for capturing and removing embolic debris from a body vessel and a system for insertion and removal of the filtering device to facilitate an interventional procedure in a stenosed or occluded region of a body vessel. The filtering device is adapted to be expandable in the body vessel, allowing blood to pass therethrough while maintaining apposition with the body vessel wall and capturing embolic material released into the bloodstream during the interventional procedure, and to be collapsible to remove the captured embolic material from the body vessel. The filtering device includes a guide wire, an expandable cage assembly secured to the guide wire, filter material secured to the expandable cage assembly, and at least one hinge, the hinge allowing the expandable cage assembly to bend independent from the guide wire. The system, which includes a delivery sheath and filtering device, is adapted to retain the expandable cage assembly in a collapsed condition and deliver and deploy the filtering device at a location in the body vessel distal the treatment site.

32. 发明授权

US06679902B1 Reduced profile delivery sheath for use in interventional procedures 有权
标题翻译：减少型材输送护套用于介入手术
公开(公告)号：US06679902B1
公开(公告)日：2004-01-20
申请号：US09619001
申请日：2000-07-19
申请人： William J. Boyle , Andy E. Denison , Benjamin C. Huter
发明人： William J. Boyle , Andy E. Denison , Benjamin C. Huter
IPC分类号： A61M2900
CPC分类号： A61M25/0068 , A61F2/95 , A61F2250/0098 , A61M25/0069 , A61M25/0108 , A61M2025/0081
摘要： A delivery sheath is provided for deploying a self-expanding intravascular filter. The sheath includes a stiff proximal portion which provides for good pushability and trackability through tortuous vessels and a soft, flexible, low profile, radiopaque distal tip for holding and delivering a deployable filter. The soft distal tip minimizes the formation of embolic particles that may be produced by contact between the sheath and an arterial lesion. The distal tip may be molded from a polymer containing radiopaque particles held in suspension and thereby provides for good visualization under fluroscopy.
摘要翻译：提供了用于展开自膨胀血管内过滤器的输送鞘。护套包括刚性近端部分，其通过曲折血管提供良好的推进性和可追踪性，以及柔软，柔性，低轮廓，不透射线的远端，用于保持和递送可部署的过滤器。软远侧末端使得可以通过鞘和动脉损伤之间的接触产生的栓塞颗粒的形成最小化。远侧末端可以由含有保持悬浮液的不透射线颗粒的聚合物模制，从而在荧光检查下提供良好的可视化。

33. 发明授权

US07842064B2 Hinged short cage for an embolic protection device 有权
标题翻译：铰链短笼为栓塞保护装置
公开(公告)号：US07842064B2
公开(公告)日：2010-11-30
申请号：US11496854
申请日：2006-08-01
申请人： Benjamin C. Huter , Kevin M. Magrini , John E. Papp
发明人： Benjamin C. Huter , Kevin M. Magrini , John E. Papp
IPC分类号： A61M29/00
CPC分类号： A61F2/013 , A61F2002/015 , A61F2002/018 , A61F2230/0006 , A61F2230/008
摘要： A filtering device for capturing and removing embolic debris from a body vessel and a system for insertion and removal of the filtering device to facilitate an interventional procedure in a stenosed or occluded region of a body vessel. The filtering device is adapted to be expandable in the body vessel, allowing blood to pass therethrough while maintaining apposition with the body vessel wall and capturing embolic material released into the bloodstream during the interventional procedure, and to be collapsible to remove the captured embolic material from the body vessel. The filtering device includes a guidewire, an expandable cage assembly secured to the guide wire, filter material secured to the expandable cage assembly, and at least one hinge, the hinge allowing the expandable cage assembly to bend independent from the guide wire. The system, which includes a delivery sheath and filtering device, is adapted to retain the expandable cage assembly in a collapsed condition and deliver and deploy the filtering device at a location in the body vessel distal the treatment site.
摘要翻译：一种用于从身体容器捕获和去除栓塞碎片的过滤装置，以及用于插入和移除过滤装置的系统，以便于在体内容器的狭窄或阻塞区域进行介入手术。过滤装置适于在身体容器中扩张，允许血液通过其中，同时保持与身体血管壁的配合并且在介入手术过程中捕获释放到血流中的栓塞物质，并且可收缩以将捕获的栓塞材料从身体血管。过滤装置包括导丝，固定到导丝的可膨胀保持架组件，固定到可膨胀笼组件的过滤材料以及至少一个铰链，该铰链允许可膨胀笼组件独立于导丝弯曲。包括输送护套和过滤装置的系统适于将可膨胀笼组件保持在折叠状态，并将过滤装置输送并部署在远离治疗部位的体内血管的位置。

34. 发明申请

US20100049305A1 CONVERTIBLE DELIVERY SYSTEMS FOR MEDICAL DEVICES 审中-公开
标题翻译：医疗设备可交换系统
公开(公告)号：US20100049305A1
公开(公告)日：2010-02-25
申请号：US12545602
申请日：2009-08-21
申请人： William J. Boyle , Benjamin C. Huter , John E. Papp , Jack Sahakian , Richard S. Stack
发明人： William J. Boyle , Benjamin C. Huter , John E. Papp , Jack Sahakian , Richard S. Stack
IPC分类号： A61F2/00
CPC分类号： A61M25/0668 , A61M2025/0681
摘要： A delivery system for a medical device or other devices to be deployed within a biological body including a sheath having a longitudinal joint. The joint can be either resealable or non-resealable. The joint remains intact during delivery of the medical device, thereby facilitating accurate delivery of the medical device. During removal of the sheath, the joint is separated, thereby permitting the sheath to be peeled from the medical device while maintaining the position of the device. The delivery system allows a single operator to deploy the medical device and remove the sheath.
摘要翻译：用于医疗装置或其他装置的递送系统，其将部署在包括具有纵向接头的护套的生物体内。接头可以重新密封或不可重新密封。在医疗装置的输送期间关节保持完整，从而有助于医疗装置的准确输送。在去除护套期间，接头被分离，从而允许护套在保持装置的位置的同时从医疗装置剥离。输送系统允许单个操作者部署医疗装置并移除护套。

35. 发明授权

US06645223B2 Deployment and recovery control systems for embolic protection devices 有权
公开(公告)号：US06645223B2
公开(公告)日：2003-11-11
申请号：US09845758
申请日：2001-04-30
申请人： William J. Boyle , Benjamin C. Huter , Charles R. Peterson , Donald E. Schwarten , Richard S. Stack
发明人： William J. Boyle , Benjamin C. Huter , Charles R. Peterson , Donald E. Schwarten , Richard S. Stack
IPC分类号： A61M2900
CPC分类号： A61F2/95 , A61F2/013 , A61F2002/018 , A61F2002/9517 , A61F2230/0006 , A61F2230/0067 , A61M25/09 , A61M2025/09116
摘要： A deployment control system provides controlled deployment of an embolic protection device which may include a guide wire, an expandable filter attached to the guide wire near its distal end, and a restraining sheath that maintains the expanded filter in a collapsed position. The deployment control system includes a torque control device which allows the physician to torque the guide wire into the patient's anatomy and a mechanism for preventing the guide wire from buckling as the restraining sheath is being retracted to deploy the expandable filter. A recovery control system for recovering the embolic protection device includes an inner catheter which extends within a lumen of an outer recovery sheath in a coaxial arrangement. A distal portion of the inner catheter extends beyond another recovery sheath during advancement of the recovery system into the vasculature. The recovery sheath can be advanced over the inner catheter to collapse the expandable filter. The proximal ends of the inner catheter and recovery sheath include handle portions having snap mechanisms which hold the components together as the recovery system is being advanced into the patient's vasculature.

36. 发明授权

US06554848B2 Marker device for rotationally orienting a stent delivery system prior to deploying a curved self-expanding stent 有权
标题翻译：用于在展开弯曲的自扩张支架之前旋转定向支架输送系统的标记装置
公开(公告)号：US06554848B2
公开(公告)日：2003-04-29
申请号：US09796183
申请日：2001-02-27
申请人： John F. Boylan , Benjamin C. Huter
发明人： John F. Boylan , Benjamin C. Huter
IPC分类号： A61F1100
CPC分类号： A61F2/95 , A61F2002/9665 , A61F2250/0098
摘要： A stent for use in a curved body lumen is disclosed. The stent is made from a superelastic alloy such as nickel titanium or nitinol, and optionally includes a ternary element. The superelastic alloy has a low temperature phase or martensitic phase and a high temperature phase or an austenitic phase. In the high temperature phase, the stent has a curve along the length that closely matches the curve of the vessel in the patient's anatomy. When deployed in the curved vessel of the patient, the heat set curve of the stent closely conforms to the curvature in the vessel and minimizes trauma and stress to the vessel.
摘要翻译：公开了一种用于弯曲体腔的支架。支架由超弹性合金如镍钛或镍钛诺制成，并且任选地包括三元元素。超弹性合金具有低温相或马氏体相以及高温相或奥氏体相。在高温阶段，支架具有与患者解剖结构中的血管曲线紧密匹配的长度的曲线。当部署在患者的弯曲容器中时，支架的热定形曲线与容器中的曲率紧密地一致，并且使得对血管的创伤和压力最小化。

37. 发明授权

US06569184B2 Recovery system for retrieving an embolic protection device 有权
公开(公告)号：US06569184B2
公开(公告)日：2003-05-27
申请号：US09796226
申请日：2001-02-27
申请人： Benjamin C. Huter
发明人： Benjamin C. Huter
IPC分类号： A61M2900
CPC分类号： A61F2/013 , A61F2002/018 , A61F2230/0006 , A61F2230/0067 , A61M2025/0681 , A61M2025/09183
摘要： A system for recovering an embolic protection device having an expandable filter disposed on a guide wire includes an inner catheter loaded inside a recovery sheath. The inner catheter has a distal portion which extends beyond the distal end of the recovery sheath when the recovery system is being advanced over the guide wire of the embolic protection device. The inner catheter has more flexibility than the recovery sheath, and enhances delivery through tortuous anatomy to the location of the deployed filter. Once the recovery system is advanced in close proximity to the expandable filter of the embolic protection device, the recovery sheath is advanced over distal portion of the inner catheter and over the expandable filter to collapse the filter for removal from the body vessel. The recovery sheath has sufficient column strength to collapse the expanded filter for removal from the body vessel.

38. 发明授权

US06485500B1 Emboli protection system 有权
标题翻译： Emboli保护系统
公开(公告)号：US06485500B1
公开(公告)日：2002-11-26
申请号：US09531740
申请日：2000-03-21
申请人： Arkady Kokish , Daryush Mirzaee , Eric J. Penn , Benjamin C. Huter , Kent C. B. Stalker , Gregg A. Jackson
发明人： Arkady Kokish , Daryush Mirzaee , Eric J. Penn , Benjamin C. Huter , Kent C. B. Stalker , Gregg A. Jackson
IPC分类号： A61M2900
CPC分类号： A61M25/104 , A61M2025/0079 , A61M2025/1013 , A61M2025/105 , A61M2025/1052 , A61M2025/1093 , A61M2025/1095
摘要： The emboli protection system provides one or more inflatable blocking balloons for isolation of a section of a blood vessel to prevent migration of emboli from the section during an interventional procedure, and fluid infusion and evacuation ports for flushing emboli from the isolated section. One embodiment provides for a distal blocking balloon catheter, over which an interventional device can be introduced, and a proximal blocking balloon catheter to be introduced over the interventional device for isolating a portion of a blood vessel to be treated. The blocking balloons can be perforated to provide the infusion ports, and thrombolytic inflation fluid may be used to break down and dissolve thrombus and plaque in the isolated portion of the blood vessel. The interventional therapeutic device such as an angioplasty balloon catheter may be incorporated into the distal blocking balloon catheter, or the distal and blocking proximal balloon catheters can be incorporated with the interventional therapeutic device together in one device. Infusion ports may also be provided in either or both of the distal and proximal blocking catheters.
摘要翻译：栓塞保护系统提供一个或多个可膨胀的阻塞气球，用于隔离血管的一部分，以防止在介入手术过程中栓塞从该部分移位，以及用于从隔离部分冲洗栓塞的流体输注和排出口。一个实施例提供远端阻塞气囊导管，介入装置可以在其上引入，以及近端阻塞气囊导管，其被引入到介入装置上，用于隔离待治疗血管的一部分。阻塞气囊可以被穿孔以提供输注口，并且可以使用溶栓膨胀流体来分解和溶解血管的孤立部分中的血栓和斑块。诸如血管成形术气囊导管的介入治疗装置可以并入到远端阻塞气囊导管中，或者远端和阻塞近端球囊导管可以与介入治疗装置并入一个装置中。输液口也可以设置在远端和近端阻塞导管中的一个或两者中。

39. 发明授权

US06592606B2 Hinged short cage for an embolic protection device 有权
标题翻译：铰链短笼为栓塞保护装置
公开(公告)号：US06592606B2
公开(公告)日：2003-07-15
申请号：US09944633
申请日：2001-08-31
申请人： Benjamin C. Huter , Kevin M. Magrini , John E. Papp
发明人： Benjamin C. Huter , Kevin M. Magrini , John E. Papp
IPC分类号： A61M2900
CPC分类号： A61F2/013 , A61F2002/015 , A61F2002/018 , A61F2230/0006 , A61F2230/008
摘要： A filtering device for capturing and removing embolic debris from a body vessel and a system for insertion and removal of the filtering device to facilitate an interventional procedure in a stenosed or occluded region of a body vessel. The filtering device is adapted to be expandable in the body vessel, allowing blood to pass therethrough while maintaining apposition with the body vessel wall and capturing embolic material released into the bloodstream during the interventional procedure, and to be collapsible to remove the captured embolic material from the body vessel. The filtering device includes a guide wire, an expandable cage assembly secured to the guide wire, filter material secured to the expandable cage assembly, and at least one hinge, the hinge allowing the expandable cage assembly to bend independent from the guide wire. The system, which includes a delivery sheath and filtering device, is adapted to retain the expandable cage assembly in a collapsed condition and deliver and deploy the filtering device at a location in the body vessel distal the treatment site.
摘要翻译：一种用于从身体容器捕获和去除栓塞碎片的过滤装置，以及用于插入和移除过滤装置的系统，以便于在体内容器的狭窄或阻塞区域进行介入手术。过滤装置适于在身体容器中扩张，允许血液通过其中，同时保持与身体血管壁的配合并且在介入手术过程中捕获释放到血流中的栓塞物质，并且可收缩以将捕获的栓塞材料从身体血管。过滤装置包括引导线，固定到引导线的可膨胀保持架组件，固定到可膨胀保持架组件的过滤材料以及至少一个铰链，铰链允许可膨胀笼组件独立于导丝弯曲。包括输送护套和过滤装置的系统适于将可膨胀笼组件保持在折叠状态，并将过滤装置输送并部署在远离治疗部位的体内血管的位置。

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