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31. 发明申请

US20100121398A1 IMPLANTABLE MEDICAL DEVICE AND METHOD FOR MONITORING VALVE MOVEMENTS OF A HEART 审中-公开
标题翻译：用于监测心脏瓣膜运动的可植入医疗装置和方法
公开(公告)号：US20100121398A1
公开(公告)日：2010-05-13
申请号：US12597227
申请日：2007-04-27
申请人： Anders Björling , Cecilia Tuvstedt , Kenth Nilsson , Kjell Norén
发明人： Anders Björling , Cecilia Tuvstedt , Kenth Nilsson , Kjell Norén
IPC分类号： A61N1/368
CPC分类号： A61N1/36521 , A61N1/36578 , A61N1/3682
摘要： An implantable medical device for monitoring the movements of the valve planes of the heart to determine at least one hemodynamic measure reflecting a mechanical functioning of a heart of a patient, includes an impedance measuring circuit that measures impedance between at least electrode pairs including at least one electrode placed substantially at the level of the valve plane. The measured impedances reflect valve plane movements. A hemodynamic parameter determining circuit determines at least one hemodynamic parameter based on the impedances reflecting the mechanical functioning of the heart.
摘要翻译：一种可植入医疗装置，用于监测心脏的瓣膜平面的移动以确定反映患者心脏的机械功能的至少一个血流动力学量度，包括阻抗测量电路，其测量至少包括至少一个电极基本上位于阀平面的水平面上。测量的阻抗反映了阀平面运动。血液动力学参数确定电路基于反映心脏的机械功能的阻抗来确定至少一个血液动力学参数。

32. 发明申请

US20100113961A1 MEDICAL DEVICE FOR DETERMINING THE POSTURE OF PATIENT 有权
标题翻译：用于确定患者症状的医疗装置
公开(公告)号：US20100113961A1
公开(公告)日：2010-05-06
申请号：US11993254
申请日：2005-06-29
申请人： Malin Öhlander , Nils Holmström , Kjell Norén
发明人： Malin Öhlander , Nils Holmström , Kjell Norén
IPC分类号： A61B5/053
CPC分类号： G06F19/34 , A61B5/0031 , A61B5/01 , A61B5/029 , A61B5/053 , A61B5/0816 , A61B5/1116 , A61B5/4561 , A61B5/686
摘要： The present invention relates to a method for determining the posture of a patient. The method comprises the steps of: initiating (50, 52) a patient posture determining session by performing an electrical bio-impedance measurement session in at least one of a number of different electrode configurations in order to measure an impedance value for the at least one configuration; obtaining reference impedance values (54) stored in advance for the at least one configuration and for at least one potential posture of the patient; comparing (54) the measured impedance value for the at least one configuration with corresponding stored reference impedance values for at least one potential posture of the patient; and determining (56) the present posture of the patient by using results from the comparison between measured impedance values and the stored reference impedance values. Furthermore, the invention relates to a medical device for determining the posture of a patient and a computer readable medium comprising instructions for bringing a computer to perform the inventive method.
摘要翻译：本发明涉及一种用于确定患者姿势的方法。该方法包括以下步骤：通过在多个不同电极配置中的至少一个中执行电生物阻抗测量会话来启动（50,52）患者姿势确定会话，以便测量至少一个组态; 获得针对所述至少一个配置和所述患者的至少一个潜在姿势预先存储的参考阻抗值（54）; 将所述至少一个配置的测量阻抗值与所述患者的至少一个潜在姿势的对应存储的参考阻抗值进行比较（54）; 以及通过使用测量的阻抗值与所存储的参考阻抗值之间的比较的结果来确定（56）患者的当前姿势。此外，本发明涉及一种用于确定患者姿势的医疗装置和包括用于使计算机执行本发明的方法的指令的计算机可读介质。

33. 发明授权

US07164947B2 Heart stimulator with stimulation controlled by analysis of an average impedance morphology curve 失效
标题翻译：通过分析平均阻抗形态曲线控制刺激的心脏刺激器
公开(公告)号：US07164947B2
公开(公告)日：2007-01-16
申请号：US10619354
申请日：2003-07-14
申请人： Nils Holmström , Anders Björling , Kjell Norén , Karin Ljungström , Sven Kalling
发明人： Nils Holmström , Anders Björling , Kjell Norén , Karin Ljungström , Sven Kalling
IPC分类号： A61N1/365
CPC分类号： A61N1/36521 , A61N1/3627
摘要： A heart stimulator for electric stimulation of a patient's heart has an impedance measuring unit that measures the impedance between at least two measurement electrodes implanted in a patient such that volume changes of at least one of the chambers of the left heart result in changes in the measured impedance. An analyzer analyzes the measured impedance for the control of the stimulation of the heart. A calculation unit calculates an average impedance morphology curve during a time interval of several cardiac cycles. The analyzer analyzes the average impedance morphology curve for use for the control of the stimulation to optimize the patient hemodynamics.
摘要翻译：用于对患者心脏进行电刺激的心脏刺激器具有阻抗测量单元，其测量植入患者体内的至少两个测量电极之间的阻抗，使得左心脏的至少一个腔室的体积变化导致测量的变化阻抗。分析仪分析测量的阻抗以控制心脏的刺激。计算单元在几个心动周期的时间间隔内计算平均阻抗形态曲线。分析仪分析用于控制刺激的平均阻抗形态曲线，以优化患者的血液动力学。

34. 发明授权

US07058448B2 Dual chamber pacing system with a mode switch 失效
标题翻译：双腔起搏系统带有一个模式开关
公开(公告)号：US07058448B2
公开(公告)日：2006-06-06
申请号：US10478144
申请日：2002-09-23
申请人： Kjell Norén
发明人： Kjell Norén
IPC分类号： A61N1/362
CPC分类号： A61N1/3622 , A61N1/3688
摘要： A dual chamber pacing system normally operates in an atrial synchronized mode, and includes a mode switch that switches the pacing mode to a non-atrial synchronized ventricular stimulating mode in response to the detection of an atrial tachyarrhythmia, and switches the pacing mode back to the atrial synchronized mode in response to, or after a preset time following, detection of cessation of the atrial tachyarrhythmia. A mode switch supervising circuit includes a counter that accumulates an amount of mode switches from a starting point, and supplies the accumulated amount to a comparator, wherein the accumulated amount is compared to a predetermined mode switch amount threshold. The mode switch supervising circuit controls the mode switch to lock the pacing mode to the non-atrial synchronized ventricular stimulating mode for at least a predetermined time period in response to the mode switch amount exceeding the amount threshold.
摘要翻译：双室起搏系统通常以心房同步模式操作，并且包括模式切换器，其响应于心房快速性心律失常的检测而将起搏模式切换到非心房同步心室刺激模式，并将起搏模式切换回心房同步模式响应或预设时间之后，检测到心房骤停的停止。模式切换监控电路包括：计数器，其从起始点累积模式切换量，并将累加量提供给比较器，其中累积量与预定模式切换量阈值进行比较。模式切换监控电路响应于模式切换量超过量阈值，控制模式切换以将起搏模式锁定至非心房同步心室刺激模式至少预定时间段。

35. 发明授权

US06860857B2 Implantable intravascular pressure determining device and method 失效
标题翻译：植入式血管内压力测定装置及方法
公开(公告)号：US06860857B2
公开(公告)日：2005-03-01
申请号：US10078210
申请日：2002-02-19
申请人： Kjell Norén , Seven-Erik Hedberg , Kenth Nilsson
发明人： Kjell Norén , Seven-Erik Hedberg , Kenth Nilsson
IPC分类号： A61B5/0215 , A61B5/00
CPC分类号： A61B5/02158 , A61B5/721
摘要： In an implantable intravascular pressure determining device and method, a pressure sensor generates a raw pressure signal and an acceleration sensor measures acceleration in a patient. Time intervals are identified wherein the raw pressure signal accurately represents the intravascular pressure, these intervals being identified as the time intervals wherein the measured acceleration is below a predetermined threshold. The raw pressure signal is processed, to generate a processed signal which is used as an intravascular pressure signal, only in the aforementioned time intervals.
摘要翻译：在可植入的血管内压力测定装置和方法中，压力传感器产生原始压力信号，加速度传感器测量患者的加速度。识别时间间隔，其中原始压力信号准确地表示血管内压力，这些间隔被识别为测量的加速度低于预定阈值的时间间隔。原始压力信号被处理，以产生用作血管内压力信号的处理信号，仅在上述时间间隔内。

36. 发明授权

US06589184B2 Implantable intravascular pressure determining device and method 失效
标题翻译：植入式血管内压力测定装置及方法
公开(公告)号：US06589184B2
公开(公告)日：2003-07-08
申请号：US10078208
申请日：2002-02-19
申请人： Kjell Norén , Seven-Erik Hedberg , Kenth Nilsson
发明人： Kjell Norén , Seven-Erik Hedberg , Kenth Nilsson
IPC分类号： A61B502
CPC分类号： A61B5/0215
摘要： In an implantable intravascular pressure determining device and method, a pressure sensor generates a raw pressure signal, an acceleration sensor generates an acceleration signal, and an evaluation unit determines a disturbance pressure signal from the acceleration signal. A processed signal is generated as the difference between the raw pressure signal and the disturbance pressure signal. The processed signal corresponds to intravascular pressure.
摘要翻译：在可植入血管内压力测定装置和方法中，压力传感器产生原始压力信号，加速度传感器产生加速度信号，评价部根据加速度信号来决定干扰压力信号。产生经处理的信号作为原始压力信号和干扰压力信号之间的差。经处理的信号对应于血管内压。

37. 发明授权

US06188928B1 Apparatus for tissue stimulation 失效
标题翻译：组织刺激装置
公开(公告)号：US06188928B1
公开(公告)日：2001-02-13
申请号：US09308077
申请日：1999-07-22
申请人： Kjell Norén , Jakub Hirschberg , Hans Strandberg
发明人： Kjell Norén , Jakub Hirschberg , Hans Strandberg
IPC分类号： A61N137
CPC分类号： A61N1/3712 , A61N1/3716
摘要： Mathematical functions such as recursive autoregression models which include parameters are used for defining the heart signal and any signals disturbing the heart signal, such as polarization signals. By registering, during a predetermined time interval, the electrode signal for determining the parameters for one or more different mathematical functions, the parameters can be used on their own or in combination to determine the activity of the heart, i.e., whether the registered electrode signal corresponds to a stimulated, spontaneous or absence of heart activity.
摘要翻译：诸如包括参数的递归自回归模型的数学函数用于定义心脏信号和干扰心脏信号的任何信号，例如偏振信号。通过在预定时间间隔内登记用于确定一个或多个不同数学函数的参数的电极信号，可以单独或组合使用这些参数以确定心脏的活动，即，是否注册的电极信号对应于刺激，自发或不存在心脏活动。

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