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31. 发明申请

WO1993014078A1 LIQUID CRYSTALLINE DIGLYCIDYL COMPOUNDS 审中-公开
标题翻译：液晶微晶化合物
公开(公告)号：WO1993014078A1
公开(公告)日：1993-07-22
申请号：PCT/US1993000201
申请日：1993-01-11
申请人： AKZO N.V. , KIM, Ki-Soo
发明人： AKZO N.V.
IPC分类号： C07D303/16
CPC分类号： C08G59/24 , C07D303/24 , C08G59/245 , C09K19/3411
摘要： The liquid crystalline compounds of structure (I) where Ar represents phenylene (e.g., bonded in their para positions) and B represents a cyclohydrocarbylene bridging group such as cyclohexylene or phenylene, are disclosed.

32. 发明申请

WO1992010530A1 PRIMARILY SOLID CONCENTRATE WHICH CONTAINS A BIOCIDE 审中-公开
标题翻译：含有生物活性的固体浓缩物
公开(公告)号：WO1992010530A1
公开(公告)日：1992-06-25
申请号：PCT/EP1991002378
申请日：1991-12-09
申请人： AKZO N.V. , VAN HOBOKEN, Nicolaas, Jan , VAN DE WORP, Roelof , VERPLOEGH, Marius, Cornelis
发明人： AKZO N.V.
IPC分类号： C08J03/22
CPC分类号： C08K5/0058 , A01N25/08 , C08J3/22 , C08J3/226
摘要： A microbiocide-containing concentrate for use in thermoplastic polymers as well as in plastisols, is disclosed. The concentrate is primarily solid at ambient conditions and comprises from 1-30 wt% of a microbiocide, a polymer plasticizer and up to 20 wt% of a thermoplastic resin. These concentrates are primarily useful as masterbatch compositions used for incorporation into polymers in order to protect said polymers from fungal or bacterial attack. Along these lines, the present document also discloses processes for incorporating these materials into a polymer or plastisol and polymers or plastisols made by these processes.
摘要翻译：公开了一种用于热塑性聚合物以及增塑溶胶中的含有杀微生物剂的浓缩物。浓缩物在环境条件下主要是固体，并且包含1-30重量％的杀微生物剂，聚合物增塑剂和至多20重量％的热塑性树脂。这些浓缩物主要用作用于掺入聚合物中的母料组合物，以保护所述聚合物免于真菌或细菌侵袭。按照这些方式，本文件还公开了将这些材料掺入聚合物或增塑溶胶中的方法以及通过这些方法制备的聚合物或增塑溶胶。

33. 发明申请

WO1992003548A1 HUMAN ZONA PELLUCIDA PROTEIN ZP3 审中-公开
标题翻译：人类ZONA PELLUCIDA蛋白ZP3
公开(公告)号：WO1992003548A1
公开(公告)日：1992-03-05
申请号：PCT/EP1991001538
申请日：1991-08-13
申请人： AKZO N.V. , VAN DUIN, Marcel
发明人： AKZO N.V.
IPC分类号： C12N15/12
CPC分类号： C07K16/28 , A61K38/00 , A61K39/00 , C07K14/705 , C07K2317/34
摘要： The invention comprises a novel polypeptide or a functional derivative thereof having human ZP3 activity or human ZP3 antigenicity. It also comprises epitopes of said polypeptide, antibodies to the polypeptides or the epitopes, as well as vaccines for contraception and methods for expressing the polypeptides in a suitable host.
摘要翻译：本发明包括具有人ZP3活性或人ZP3抗原性的新型多肽或其功能性衍生物。它还包括所述多肽的表位，多肽或表位的抗体，以及用于避孕的疫苗和用于在合适的宿主中表达多肽的方法。

34. 发明申请

WO1992001644A1 ALUMINIUM OXIDE FIBRES AND PROCESS FOR PRODUCING THEM 审中-公开
标题翻译：氧化铝纤维及其生产工艺
公开(公告)号：WO1992001644A1
公开(公告)日：1992-02-06
申请号：PCT/EP1991001362
申请日：1991-07-18
申请人： AKZO N.V. , WEGERHOFF, Arno
发明人： AKZO N.V.
IPC分类号： C04B35/00
CPC分类号： C04B41/5022 , C01F7/36 , C01P2004/10 , C01P2004/61 , C04B35/111 , C04B35/62245
摘要： The process disclosed enables aluminium oxide fibres containing up to about 40 wt % of Sio2 to be produced by reacting aluminium hydroxide or aluminium oxide hydrate with oxalic acid in an aqueous medium, optionally in the presence of an acid such as formic acid, to give aluminium oxalate, adding silicic acid and dry-spinning the solution obtained, optionally in the presence of spinning auxiliaries, and finally heating the aluminium oxalate fibres produced.
摘要翻译：所公开的方法使含有至多约40重量％的Sio2的氧化铝纤维可以通过氢氧化铝或氧化铝水合物与草酸在水性介质中反应来制备，任选地在酸如甲酸存在下反应，得到铝草酸盐，加入硅酸并干燥所得溶液，任选在纺丝助剂的存在下，最后加热生产的草酸铝纤维。

35. 发明申请

WO1991008061A1 APPARATUS AND METHOD FOR CLEANING REAGENT DELIVERY PROBES 审中-公开
标题翻译：用于清洁试剂递送探针的装置和方法
公开(公告)号：WO1991008061A1
公开(公告)日：1991-06-13
申请号：PCT/US1990007062
申请日：1990-12-03
申请人： AKZO N.V. , HOFFMAN, Julie, Frances , JONES, Lionel, Dacie
发明人： AKZO N.V.
IPC分类号： B08B09/02
CPC分类号： G01N35/1004 , G01N35/1083
摘要： A cleaning apparatus for cleaning delivery probes (4) used for dispensing protein-containing reagents. The apparatus includes: a bath (12) of a cleaning solution (14) for a protein-containing reagent; a device for immersing the probe (4) in the cleaning solution (14) for aspirating cleaning solution (14) into the probe (4) and for coating the outside of the probe (4); a device for raising the probe (4) from the cleaning solution (14); a device for forcing primer liquid through the probe (4) for expelling aspirated cleaning solution (14) followed by primer liquid from the probe for washing the inside of the probe (4); and a device (22) for deflecting cleaning solution (14) and primer liquid expelled from the probe (4) onto the outside of the probe (4) for washing the outside of the probe (4).

36. 发明申请

WO1991004005A1 COMPARTMENTALIZED CONTAINER FOR A PLURALITY OF SMALL ARTICLES 审中-公开
标题翻译：大量小型文具的集装箱
公开(公告)号：WO1991004005A1
公开(公告)日：1991-04-04
申请号：PCT/EP1990001544
申请日：1990-09-10
申请人： AKZO N.V. , OUWERKERK, Conny
发明人： AKZO N.V.
IPC分类号： A61J07/04
CPC分类号： A61J7/04
摘要： The invention relates to a container with a plurality of compartments, especially capsules or pills. More specifically it relates to a container for oral contraceptives. The invention resides in an oblong strip (10) with a single row of pockets (11) forming compartments for said pills and which strip (10) is provided with means (12) enabling time adjustment.

37. 发明申请

WO1991002013A1 BISCITRACONIMIDE COPOLYMERS WITH OLEFINICALLY UNSATURATED MATERIALS 审中-公开
标题翻译：具有烯烃不饱和材料的双组分共聚物
公开(公告)号：WO1991002013A1
公开(公告)日：1991-02-21
申请号：PCT/EP1990001077
申请日：1990-07-06
申请人： AKZO N.V. , VAN SWIETEN, Andreas, Petrus , TALMA, Auke, Gerardus , HOPE, Peter
发明人： AKZO N.V.
IPC分类号： C08F222/40
CPC分类号： C08J5/04 , C08F222/40 , C08G73/12 , C08J5/24 , C08J2379/08
摘要： Curable bisimide compositions containing at least one biscitraconimide having general formula (I), wherein D is a divalent group, R is CH2-R1, and R1 is independently selected from hydrogen and alkyl groups having 1-18 carbon atoms; at least one olefinically unsaturated material, and 0-15 mole percent, based on biscitraconimide of formula (I), of a cocurable material selected from the group consisting of bismaleimides, citraconic maleimides and itaconic maleimides, wherein the mole ratio of biscitraconimide of formula (I), to olefinically unsaturated materials is from 0.12 to 4.0; are disclosed. Also disclosed are copolymeric compositions of biscitraconimides and olefinically unsaturated materials, processes for making these copolymers and articles of manufacture embodying these copolymers. These copolymers exhibit improved thermostability, high glass transition temperature, are solvent resistant and are void-free. In addition, these curable materials are easily processed due to the large melt-cure window, low viscosity of the melt, low melting points of the biscitraconimides and the fact that curing can often be accomplished without additional solvents.
摘要翻译：含有至少一种具有通式（I）的双柠檬酰亚胺的可固化双酰亚胺组合物，其中D是二价基团，R是CH 2 -R 1，R 1独立地选自氢和具有1-18个碳原子的烷基; 至少一种烯属不饱和物质，和基于式（I）的双柠康酰亚胺的0-15摩尔％的选自双马来酰亚胺，柠康马来酰亚胺和衣康酸马来酰亚胺的可共性材料，其中式（I）的双柠康酰亚胺的摩尔比对于烯属不饱和物质，为0.12〜4.0; 被披露。还公开了双柠檬酰亚胺和烯属不饱和材料的共聚组合物，制备这些共聚物的方法和体现这些共聚物的制品。这些共聚物表现出改善的热稳定性，高玻璃化转变温度，耐溶剂且无空隙。此外，这些可固化材料由于熔融固化窗口大，熔融粘度低，二柠康酰亚胺的低熔点以及固化常常可以在没有其他溶剂的情况下完成的事实而易于加工。

38. 发明申请

WO1991001971A1 STERICALLY HINDERED DIAMINES AND POLYMERS PREPARED THEREFROM 审中-公开
标题翻译：异丙肾上腺素和制备的聚合物
公开(公告)号：WO1991001971A1
公开(公告)日：1991-02-21
申请号：PCT/EP1990001212
申请日：1990-07-18
申请人： AKZO N.V. , BOUWMANS, Theodorus, Johannes , HOENTJEN, Gerrit , DE JONGE, Cornelis, Reinier, Heinrich, Izaäc
发明人： AKZO N.V.
IPC分类号： C07C233/80
CPC分类号： C08G73/14 , C07C233/80 , C08G69/26 , C08G73/1067
摘要： The invention comprises diamines having a 5-t-butyl-1,3-benzene dicarboxylic moiety linked on both sides to phenylene diamine by an amide bond (tBuIPA-diamines). By reacting these diamines with aromatic difunctional acid derivatives amorphous polymers having high glass transition temperatures (Tg) can be prepared. If aliphatic diacid derivatives are used, the resulting polymers have a lower Tg, but have the advantage of melt-processability. The t-BuIPA diamines can also be used in the preparation of polyimides, being reacted with tri- or tetra-carboxylic anhydrides or with imide group-containing acid derivatives.
摘要翻译：本发明包括具有通过酰胺键（tBuIPA-二胺）在两侧与苯二胺相连的5-叔丁基-1,3-苯二羧酸部分的二胺。通过使这些二胺与芳族二官能酸衍生物反应，可以制备具有高玻璃化转变温度（Tg）的无定形聚合物。如果使用脂族二酸衍生物，则所得聚合物具有较低的Tg，但具有熔融加工性的优点。 t-BuIPA二胺也可用于制备聚酰亚胺，与三 - 或四羧酸酐或含酰亚胺基的酸衍生物反应。

39. 发明申请

WO1990015625A1 RADIOIMMUNOTHERAPY USING 'alpha'-PARTICLES EMISSION 审中-公开
标题翻译：使用α - 氨基酸排放的放射治疗
公开(公告)号：WO1990015625A1
公开(公告)日：1990-12-27
申请号：PCT/EP1990000990
申请日：1990-06-19
申请人： AKZO N.V. , GEERLINGS, Maurits, Willem , KASPERSEN, Franciscus, Michael
发明人： AKZO N.V.
IPC分类号： A61K43/00
CPC分类号： A61K51/1093 , A61K2121/00 , A61K2123/00
摘要： The present invention relates to the use of Actinium or one of its daughters in radioimmunotherapy. Also provided are immunoconjugates comprising an isotope, a chelating agent and a slowly localizing antibody. The invention also includes pharmaceutical compositions comprising said immunoconjugates, as well as such compositions comprising one or more scavenging agents. The compositions according to the invention are particularly useful for the treatment of micrometastases in adjuvant therapy, as well as for treatment of localized tumors.

40. 发明申请

WO1990014414A1 APPARATUS FOR DETECTION OF MICROORGANISMS 审中-公开
标题翻译：用于检测微生物的装置
公开(公告)号：WO1990014414A1
公开(公告)日：1990-11-29
申请号：PCT/US1990002631
申请日：1990-05-14
申请人： AKZO N.V.
发明人： AKZO N.V. , DIGUISEPPI, James, L. , THORPE, Thurman, C.
IPC分类号： C12M01/34
CPC分类号： C12M41/46 , G01N21/253 , G01N21/80 , G01N21/8483
摘要： An instrument for monitoring the color change of an indicator element (2) sealed within a sterile vessel (1) and exhibiting a color change in response to a change in the pH or CO2 level within the sterile vessel (1) as a result of microbacterial growth within a specimen contained in the sterile vessel (1). The present invention includes means (6, 20) for continuously monitoring the absolute value of the pH and/or CO2 level within the vessel and/or monitoring the rate of change of the absolute value of the pH level.
摘要翻译：用于监测密封在无菌容器（1）内的指示元件（2）的颜色变化的仪器，并且响应于由于微细菌而导致的无菌容器（1）内的pH或二氧化碳水平的变化而显示颜色变化在无菌容器（1）中包含的标本内的生长。本发明包括用于连续监测容器内的pH和/或CO 2水平的绝对值和/或监测pH水平绝对值的变化率的装置（6,20）。

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