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31. 发明申请

WO2011149733A2 NOVEL AMINO ALCOHOL CATIONIC LIPIDS FOR OLIGONUCLEOTIDE DELIVERY 审中-公开
标题翻译：用于OLIGUUCLEOTIDE交货的新型氨基酸醇酸饮料
公开(公告)号：WO2011149733A2
公开(公告)日：2011-12-01
申请号：PCT/US2011/036944
申请日：2011-05-18
申请人： MERCK SHARP & DOHME CORP. , BUDZIK, Brian, W. , COLLETTI, Steven, L. , SEIFRIED, Darla Danile , STANTON, Matthew, G. , TIAN, Lu
发明人： BUDZIK, Brian, W. , COLLETTI, Steven, L. , SEIFRIED, Darla Danile , STANTON, Matthew, G. , TIAN, Lu
IPC分类号： A61K48/00 , C07C211/63
CPC分类号： A61K47/18 , A61K31/713 , C07C217/28 , C07C217/40 , C07D263/14 , C12N15/87
摘要： The instant invention provides for novel cationic lipids that can be used in combination with other lipid components such as cholesterol and PEG-lipids to form lipid nanoparticles with oligonucleotides. It is an object of the instant invention to provide a cationic lipid scaffold that is more efficacious than traditional cationic lipids. The present invention employs amino alcohols to enhance the efficiency of in vivo delivery of siRNA.
摘要翻译：本发明提供了可以与其它脂质组分如胆固醇和PEG-脂质组合使用以与寡核苷酸形成脂质纳米颗粒的新型阳离子脂质。本发明的目的是提供比传统阳离子脂质更有效的阳离子脂质支架。本发明使用氨基醇来提高siRNA的体内递送效率。

32. 发明申请

WO2008033951A3 DELIVERY OF MOBILE TERMINATED CALL DURING INTER-VLR LOCATION UPDATE 审中-公开
标题翻译：在VLR位置更新期间传送移动终端呼叫
公开(公告)号：WO2008033951A3
公开(公告)日：2008-07-10
申请号：PCT/US2007078309
申请日：2007-09-12
申请人： ALCATEL LUCENT , ZHANG YIBO , TIAN LU , ZHAO YONG , LANDAIS BRUNO
发明人： ZHANG YIBO , TIAN LU , ZHAO YONG , LANDAIS BRUNO
IPC分类号： G06F15/16
CPC分类号： H04W8/12 , H04W8/06 , H04W60/04 , H04W76/02
摘要： A mobile terminated call is delivered to a mobile device during an inter- VLR location update by first routing the mobile terminated call to the old mobile switching center/visitor location register (MSC/VLR), determining that the mobile device is performing a location update to a new MSC/VLR at the old MSC/VLR, and then routing the mobile terminated call to the new MSC/VLR directly from the old MSC/VLR or via the gateway mobile switching center (GMSC) for connection of the mobile terminated call to the mobile device.
摘要翻译：通过首先将移动终止的呼叫路由到旧的移动交换中心/访问者位置寄存器（MSC / VLR），确定移动设备正在执行位置更新，在VLR位置更新期间将移动终止的呼叫传送到移动设备到旧的MSC / VLR的新的MSC / VLR，然后直接从旧的MSC / VLR或经由网关移动交换中心（GMSC）将移动终止的呼叫路由到新的MSC / VLR，用于连接移动终止的呼叫到移动设备。

33. 发明申请

WO2003103594A3 MICELLE ASSEMBLIES 审中-公开
公开(公告)号：WO2003103594A3
公开(公告)日：2003-12-18
申请号：PCT/US2003/017902
申请日：2003-06-06
申请人： RUTGERS, THE STATE UNIVERSITY , UHRICH, Kathryn, E. , TIAN, Lu
发明人： UHRICH, Kathryn, E. , TIAN, Lu
IPC分类号： A61K31/74
摘要： The invention encompasses micelle assemblies, compositions having micelle assemblies, and methods for preparing micelle assemblies and compositions thereof. Also, the invention encompasses compounds of the formula: A-X-Y-Z-R1 wherein A is a carboxy group or is absent; X is a polyol, Y is -C(=O)-, -C(=S)-, or is absent; Z is O, S, or NH; and R1 is a polyether, wherein one or more hydroxy groups of the polyol are acylated with a fatty acid residue, wherein the compounds form micelle assemblies. The invention encompasses methods of encapsulating molecules using the compounds of the invention.

34. 发明申请

WO2003061168A1 METHOD AND SYSTEM TO SEND SMS MESSAGES IN A HYBRID NETWORK 审中-公开
标题翻译：在混合网络中发送SMS消息的方法和系统
公开(公告)号：WO2003061168A1
公开(公告)日：2003-07-24
申请号：PCT/US2002/040897
申请日：2002-12-19
申请人： SPATIAL COMMUNICATION TECHNOLOGIES, INC. , TIAN, Lu
发明人： TIAN, Lu
IPC分类号： H04J3/02
CPC分类号： H04W4/14 , H04W88/184 , H04W92/02 , H04W92/16 , H04W92/24
摘要： Embodiments of a method and system are disclosed to pass SMS messages from a mobile (320) operating in a CDMA Radio Access Network (306) to a Hybrid MSC (308), and to route the SMS message from the Hybrid MSC (308) to a GSM short message service center SMS-C (350) in the Core network (302), the hybrid wireless network having at least one radio access network (RAN) based on CDMA technology and a core network CN based on GSM technology.
摘要翻译：公开了一种方法和系统的实施例，以将来自在CDMA无线电接入网络（306）中操作的移动台（320）的SMS消息传递到混合MSC（308），并将SMS消息从混合MSC（308）路由到核心网络（302）中的GSM短消息服务中心SMS-C（350），具有基于CDMA技术的至少一个无线电接入网络（RAN）和基于GSM技术的核心网络CN的混合无线网络。

35. 发明申请

WO2002062037A2 CALL INTERCEPT SYSTEM AND METHOD 审中-公开
标题翻译：呼叫中断系统和方法
公开(公告)号：WO2002062037A2
公开(公告)日：2002-08-08
申请号：PCT/US2001/043350
申请日：2001-11-20
申请人： NORTEL NETWORKS LIMITED , MIZELL, Jerry , WENZEL, Peter, W. , BALACHANDER, Bala , MCGOWAN, Rosemary , TIAN, Lu
发明人： MIZELL, Jerry , WENZEL, Peter, W. , BALACHANDER, Bala , MCGOWAN, Rosemary , TIAN, Lu
IPC分类号： H04L29/06
CPC分类号： H04L63/10 , H04L63/30 , H04M3/2281 , H04Q2213/13098 , H04Q2213/13372 , H04Q2213/13389
摘要： A call intercept method is disclosed. The method includes receiving a call intercept request from a delivery function using a first protocol layer common to a plurality of packet data networks. The method also includes collecting call intercept information specific to a particular packet data network technology in response to the call intercept request and delivering to the delivery function call intercept information using the first protocol layer.
摘要翻译：公开了一种呼叫截取方法。该方法包括使用多个分组数据网络公共的第一协议层从传送功能接收呼叫拦截请求。所述方法还包括响应于所述呼叫拦截请求收集特定于特定分组数据网络技术的呼叫截取信息，并且使用所述第一协议层传送到所述传送功能呼叫拦截信息。

36. 发明申请

WO2009151553A1 METHOD FOR HANDLING ROAMING OF MOBILE DEVICE TO RESTRICTED AREA 审中-公开
标题翻译：用于处理移动设备到限制区域的方法
公开(公告)号：WO2009151553A1
公开(公告)日：2009-12-17
申请号：PCT/US2009/003376
申请日：2009-06-03
申请人： ALCATEL-LUCENT USA INC. , TIAN, Lu , ZHAO, Yong
发明人： TIAN, Lu , ZHAO, Yong
IPC分类号： H04W48/04
CPC分类号： H04W48/04 , H04W60/04
摘要： As a mobile device moves from one location area to another, the mobile device detects the different location identifiers broadcast by the wireless network(s) in those locations areas. The mobile device stores the location identifier for the last location area in which the mobile device was located. By comparing a received location identifier to the stored location identifier, the mobile device determines if the mobile device has entered a new location area. If so, the mobile device sends a location update request. In one embodiment, if the location update request is for a location area to which access by the mobile device is restricted, the network sends a communication to the mobile device that triggers the mobile device to update a location identifier stored at the mobile device to the location identifier for the restricted location area so that the mobile can update the network after entering/selecting a different location area.
摘要翻译：随着移动设备从一个位置区域移动到另一个位置区域，移动设备检测由那些位置区域中的无线网络广播的不同位置标识符。移动设备存储移动设备所在的最后位置区域的位置标识符。通过将接收到的位置标识符与存储的位置标识符进行比较，移动设备确定移动设备是否已经进入新的位置区域。如果是，则移动设备发送位置更新请求。在一个实施例中，如果位置更新请求是针对移动设备的访问受到限制的位置区域，则网络向触摸移动设备的移动设备发送通信，以将存储在移动设备处的位置标识符更新为用于受限位置区域的位置标识符，使得移动台可以在进入/选择不同位置区域之后更新网络。

37. 发明申请

WO2009129387A2 CATIONIC LIPIDS AND USES THEREOF 审中-公开
标题翻译：阳离子脂肪及其用途
公开(公告)号：WO2009129387A2
公开(公告)日：2009-10-22
申请号：PCT/US2009040803
申请日：2009-04-16
申请人： ABBOTT LAB , DANDE PRASAD A , HANSEN TODD M , HUBBARD ROBERT D , WADA CAROL K , TIAN LU , ZHAO XIAOBIN
发明人： DANDE PRASAD A , HANSEN TODD M , HUBBARD ROBERT D , WADA CAROL K , TIAN LU , ZHAO XIAOBIN
IPC分类号： C07C217/28 , C07C219/06 , C07C219/08 , C07C235/08 , C07C237/08 , C07C271/16
CPC分类号： A61K9/0019 , A61K9/1272 , A61K9/1277 , A61K47/543 , A61K47/6911 , C07C235/08 , C07C271/16 , C07D203/10 , C07D207/06 , C07D207/14 , C07D211/44 , C07D211/58 , C07D233/61 , C07D295/088 , C07D317/28 , C12N15/88
摘要： Cationic lipids, cationic lipid based drug delivery systems, ways to make them and methods of treating diseases using them are disclosed.
摘要翻译：公开了阳离子脂质，基于阳离子脂质的药物递送系统，其制备方法和使用它们治疗疾病的方法。

38. 发明申请

WO2008037572A1 METHOD AND APPARATUS FOR INTEGRATING RELATIONAL AND HIERARCHICAL DATA 审中-公开
标题翻译：整合关系和分层数据的方法与装置
公开(公告)号：WO2008037572A1
公开(公告)日：2008-04-03
申请号：PCT/EP2007/059304
申请日：2007-09-05
申请人： INTERNATIONAL BUSINESS MACHINES CORPORATION , IBM UNITED KINGDOM LIMITED , KHORLIN, Andrey , STROM, Robert, Evan , TIAN, Lu
发明人： KHORLIN, Andrey , STROM, Robert, Evan , TIAN, Lu
IPC分类号： G06F17/30
CPC分类号： G06F17/30908
摘要： Methods and apparatus for integrating relational and hierarchical data, schema definitions, and queries in a data processing system are provided. It is determined if one or more schema definit ions or one or more query expressions are provided as input to the data processing system. The one or more schema definitions are converted into an intermediate schema language component of an intermediate data language when one or more schema definitions are provided. The one or more query expressions are converted into an intermediate query language component of the intermediate data language when one or more query expressions are provided. The intermediate schema language component or the intermediate query language component is compiled in an intermediate data language processing engine into a run-time representation in accordance with a relational-hierarchical analysis.
摘要翻译：提供了在数据处理系统中集成关系和层次数据，模式定义和查询的方法和装置。确定是否提供了一个或多个模式定义离子或一个或多个查询表达式作为数据处理系统的输入。当提供一个或多个模式定义时，将一个或多个模式定义转换为中间数据语言的中间模式语言组件。当提供一个或多个查询表达式时，一个或多个查询表达式被转换成中间数据语言的中间查询语言组件。中间模式语言组件或中间查询语言组件根据关系分层分析在中间数据语言处理引擎中编译成运行时表示。

39. 发明申请

WO2008033951A2 DELIVERY OF MOBILE TERMINATED CALL DURING INTER-VLR LOCATION UPDATE 审中-公开
标题翻译：在VLR位置更新期间交付移动终端呼叫
公开(公告)号：WO2008033951A2
公开(公告)日：2008-03-20
申请号：PCT/US2007/078309
申请日：2007-09-12
申请人： ALCATEL-LUCENT , ZHANG, Yibo , TIAN, Lu , ZHAO, Yong , LANDAIS, Bruno
发明人： ZHANG, Yibo , TIAN, Lu , ZHAO, Yong , LANDAIS, Bruno
IPC分类号： H04K1/04
CPC分类号： H04W8/12 , H04W8/06 , H04W60/04 , H04W76/10
摘要： A mobile terminated call is delivered to a mobile device during an inter- VLR location update by first routing the mobile terminated call to the old mobile switching center/visitor location register (MSC/VLR), determining that the mobile device is performing a location update to a new MSC/VLR at the old MSC/VLR, and then routing the mobile terminated call to the new MSC/VLR directly from the old MSC/VLR or via the gateway mobile switching center (GMSC) for connection of the mobile terminated call to the mobile device.
摘要翻译：在VLR间位置更新期间，通过首先将移动终止的呼叫路由到旧的移动交换中心/访问位置寄存器（MSC / VLR），将移动终止的呼叫传送到移动设备，确定移动设备正在旧的MSC / VLR处对新的MSC / VLR执行位置更新，然后将移动终止的呼叫直接从旧的MSC / VLR或经由网关移动交换中心（GMSC）路由到新的MSC / VLR ）用于将移动终止的呼叫连接到移动设备。

40. 发明申请

WO2004008720B1 METHOD AND SYSTEM FOR THE USE OF DIFFERENT WIRELESS TECHNOLOGIES WITHIN A HYBRID SWITCH PROTOCOL STACK 审中-公开
标题翻译：在混合开关协议栈中使用不同无线技术的方法和系统
公开(公告)号：WO2004008720B1
公开(公告)日：2004-05-27
申请号：PCT/US0322086
申请日：2003-07-12
申请人： SPATIAL WIRELESS INC , TIAN LU , XU JIANMING
发明人： TIAN LU , XU JIANMING
IPC分类号： H04L29/06 , H04W4/12 , H04W88/14 , H04W88/16 , H04M1/00 , H04Q7/20
CPC分类号： H04W88/16 , H04L69/08 , H04L69/18 , H04W4/12 , H04W88/14
摘要： Provided is a method and system for enabling communication between mobile devices (102, 202), radio access networks (RANs; 104, 204), and core networks (CNs; 302) based on different specifications and underlying technologies. For example, a mobile station (MS; 102, 202) may be compatible with multiple standards or specifications (e.g., GSM and CDMA), and may need to communicate with a network via an interface that is not compatible with the network (e.g., a GSM network and a CDMA interface). A hybrid MSC (304) that is compatible with both standards may be provided between the GSM network and the CDMA interface. In some examples, the hybrid MSC (304) may inherit components or functionality from both the network and the interface, which enables the hybrid MSC (304) to handle messages from both without needing to change either of them. For example, the hybrid MSC (304) may receive messages from the network and encapsulate them in one or more messages compatible with the interface for transmission over the interface.
摘要翻译：提供了一种用于基于不同规格和底层技术实现移动设备（102,202），无线电接入网络（RAN; 104,204）和核心网络（CNs; 302）之间的通信的方法和系统。例如，移动站（MS; 102,202）可以与多个标准或规范（例如，GSM和CDMA）兼容，并且可能需要经由与网络不兼容的接口与网络进行通信（例如， GSM网络和CDMA接口）。可以在GSM网络和CDMA接口之间提供与两个标准兼容的混合MSC（304）。在一些示例中，混合MSC（304）可以从网络和接口两者继承组件或功能，这使得混合MSC（304）能够处理来自两者的消息，而不需要改变它们中的任何一个。例如，混合MSC（304）可以从网络接收消息并将其封装在与该接口兼容的一个或多个消息中，以在接口上传输。

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