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    • 31. 发明授权
    • Selection of data to be transmitted between nodes in a network having limited bandwidth
    • 选择要在具有有限带宽的网络中的节点之间传送的数据
    • US07167452B2
    • 2007-01-23
    • US10200958
    • 2002-07-23
    • Stephen Mitchell JamesonHenry Hindle MendenhallKenneth Robert WhitebreadLori Ann Pridmore
    • Stephen Mitchell JamesonHenry Hindle MendenhallKenneth Robert WhitebreadLori Ann Pridmore
    • H04L12/54
    • H04L67/12H04L67/10H04L67/322
    • Communication is provided among plural nodes by a network having finite bandwidth between the nodes. The bandwidth may differ for each direction of propagation. Each node includes a processor for processing locally available data, including data derived locally and available through relatively high-bandwidth paths. When processing at any one of the nodes may be improved by incorporating into the data being processed information which is locally available at another node, at least one node is configured to know (a) the directional bandwidth from itself to the remote node(s) of the system, and (b) also to have knowledge, of the relative improvement to be realized at the first node by incorporation of data of the second node into the processing of the first node. The second node selects portions of its own local data for transmission to the first node which yield large improvement and can be transmitted within the available directional bandwidth. (149)
    • 通过在节点之间具有有限带宽的网络在多个节点之间提供通信。 每个传播方向的带宽可能不同。 每个节点包括用于处理本地可用数据的处理器,包括本地导出的数据,并通过相对高带宽的路径可用。 当在任何一个节点上的处理可以通过将被处理的数据合并到在另一个节点处本地可用的信息来改进,至少一个节点被配置为知道(a)从自身到远程节点的方向带宽, 以及(b)通过将第二节点的数据结合到第一节点的处理中,还具有要在第一节点实现的相对改进的知识。 第二节点选择其本地本地数据的部分以便传输到第一节点,其产生大的改进,并且可以在可用的方向带宽内传输。 (149)
    • 36. 发明申请
    • ELECTROMECHANICAL STRUT
    • 电动力学
    • US20070194599A1
    • 2007-08-23
    • US11678631
    • 2007-02-26
    • Gordon PatonStephen Mitchell
    • Gordon PatonStephen Mitchell
    • B60J5/00
    • B60J5/101E05F1/1058E05F1/1083E05F15/622E05Y2201/434E05Y2201/72E05Y2800/242E05Y2900/546E05Y2900/548
    • An electromechanical strut is provided for moving a pivotal lift gate between an open position and a closed position relative to a motor vehicle body. The electromechanical strut includes a housing connected to one of the lift gate and the motor vehicle body. An extensible shaft is slidably mounted to the housing. The extensible shaft is connected to the other of the lift gate and the motor vehicle body. A drive mechanism includes a rotatable power screw. The drive mechanism converts rotary motion of the power screw into linear motion of the extensible shaft to move the extensible shaft between a retracted position corresponding to the closed position of the lift gate and an extended position corresponding to the open position of the lift gate. A power spring includes one end connected to the extensible shaft and another end connected to the housing for providing a mechanical counterbalance to the weight of the lift gate.
    • 提供了一种机电支柱,用于使枢转升降门相对于机动车体在打开位置和关闭位置之间移动。 机电支柱包括连接到提升门和机动车体之一的壳体。 可伸缩轴可滑动地安装在壳体上。 可伸长轴连接到提升门和机动车体中的另一个。 驱动机构包括可旋转的动力螺钉。 驱动机构将动力螺杆的旋转运动转换成可延伸轴的直线运动,以使可延伸轴在对应于提升门的关闭位置的缩回位置和对应于提升门的打开位置的延伸位置之间移动。 动力弹簧包括连接到可延伸轴的一端和连接到壳体的另一端,用于提供对升降门重量的机械平衡。
    • 38. 发明申请
    • Novel serpentine transmembrane antigens expressed in human cancers and uses thereof
    • 在人类癌症中表达的新型蛇纹石跨膜抗原及其用途
    • US20070104720A1
    • 2007-05-10
    • US11580538
    • 2006-10-12
    • Daniel AfarRene HubertKahan LeongArthur RaitanoDouglas SaffranStephen Mitchell
    • Daniel AfarRene HubertKahan LeongArthur RaitanoDouglas SaffranStephen Mitchell
    • A61K39/395C07H21/04C12P21/06C07K14/82C07K16/30C07K16/46
    • C07K14/4748C07K14/705C07K14/723C07K16/28C07K16/3069C07K2317/34C07K2319/00Y10T436/143333
    • Described is a novel family of cell surface serpentine transmembrane antigens. Two of the proteins in this family are exclusively or predominantly expressed in the prostate, as well as in prostate cancer, and thus members of this family have been termed “STEAP” (SIX Transmembrane Epithelial Antigens of the Prostate). Four particular human STEAPs are described and characterized herein. The human STEAPs exhibit a high degree of structural conservation among them but show no significant structural homology to any known human proteins. The prototype member of the STEAP family, STEAP-1, appears to be a type IIIa membrane protein expressed predominantly in prostate cells in normal human tissues. Structurally, STEAP-1 is a 339 amino acid protein characterized by a molecular topology of six transmembrane domains and intracellular N— and C-termini, suggesting that it folds in a “serpentine” manner into three extracellular and two intracellular loops. STEAP-1 protein expression is maintained at high levels across various stages of prostate cancer. Moreover, STEAP-1 is highly over-expressed in certain other human cancers.
    • 描述了一种新型的细胞表面蛇纹石跨膜抗原家族。 该家族中的两种蛋白质仅在或主要地在前列腺中表达,并且在前列腺癌中,因此该家族的成员被称为“STEAP”(前列腺的第六跨膜上皮原体)。 本文描述和表征了四种特定的人STEAP。 人类STEAP在其中表现出高度的结构保守性,但与任何已知的人类蛋白质没有显着的结构同源性。 STEAP家族的原型成员STEAP-1似乎是主要在正常人体组织中的前列腺细胞中表达的IIIa型膜蛋白。 在结构上,STEAP-1是一种339个氨基酸的蛋白质,其特征在于六个跨膜结构域和细胞内N-和C-末端的分子拓扑结构,表明它以“蛇纹石”的方式折叠成三个胞外和两个细胞内环。 STEAP-1蛋白表达在前列腺癌的各个阶段保持在高水平。 此外,STEAP-1在某些其他人类癌症中高度过度表达。