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31. 发明公开

EP1429649A2 METHODS AND APPARATUS EMPLOYING IONIZING RADIATION FOR TREATMENT OF CARDIAC ARRHYTHMIA 审中-公开
标题翻译：方法和装置与电离辐射心脏治疗心律失常
公开(公告)号：EP1429649A2
公开(公告)日：2004-06-23
申请号：EP02768885.2
申请日：2002-09-23
申请人： Novoste Corporation
发明人： BONAN, Raoul , LARSEN, Charles, E. , TRIP, Roelof , SCHUMER, Douglas, B. , GRIFFIS, Jack, C., III , LEROHL, Andrew, L.
IPC分类号： A61B1/00
CPC分类号： A61N5/1002 , A61B2017/003 , A61B2018/00363 , A61B2018/00559 , A61B2018/00577 , A61M25/0147 , A61M2025/0034 , A61M2025/004
摘要： Method and apparatus (20) employing ionizing radiation for forming lines of ablation or lesions in cardiac tissue to treat atrial fibrillation or other electrophysiological problems with the heart. The apparatus (20) may include a catheter (20) in which a radiation source (42) is advanced hydraulically after the catheter (20) is in place within the heart. Various fixation devices (72) are also disclosed for fixing the location of the catheter (20) within the heart.

32. 发明授权

EP1159982B1 Wound treating device 失效
标题翻译：伤口处理装置
公开(公告)号：EP1159982B1
公开(公告)日：2003-09-03
申请号：EP01119163.2
申请日：1994-06-08
申请人： NOVOSTE CORPORATION
发明人： Weldon, Thomas D. , Larsen, Charles E. , Rosen, Jonathan J.
IPC分类号： A61M25/01 , A61B17/00
CPC分类号： A61M25/0119 , A61B17/0057 , A61F2/06 , A61F2013/00357 , A61F2013/00472 , A61M25/10 , A61M2025/1015

33. 发明授权

EP0668086B1 Wound treating device 失效
公开(公告)号：EP0668086B1
公开(公告)日：2002-09-18
申请号：EP94108819.7
申请日：1994-06-08
申请人： NOVOSTE CORPORATION
发明人： Weldon, Thomas D. , Larsen, Charles E. , Rosen, Jonathan J.
IPC分类号： A61M25/01 , A61B17/00
CPC分类号： A61M25/0119 , A61B17/0057 , A61F2/06 , A61F2013/00357 , A61F2013/00472 , A61M25/10 , A61M2025/1015

34. 发明公开

EP1140274A1 AUTOMATED SYSTEM FOR THE RADIATION TREATMENT OF A DESIRED AREA WITHIN THE BODY OF A PATIENT 有权
标题翻译：自动化系统所要求的区域内的病人体内放射治疗
公开(公告)号：EP1140274A1
公开(公告)日：2001-10-10
申请号：EP99968900.3
申请日：1999-12-22
申请人： Novoste Corporation
发明人： HUGHETT, James, D. , WEBSTER, Robert, Michael , ARMSTRONG, Doug, Layland , BOYLSTON, Byron, Lee , JUETT, Gregg, T. , HILLSTEAD, Richard, A. , GRIFFIS, Jack, C., III. , LEROHL, Andrew, L. , DEDASHTIAN, Mark , GUILES, Marvin, A.
IPC分类号： A61M36/00
CPC分类号： A61N5/1007 , A61N2005/1008
摘要： This invention is a transfer device usable in a system for intraluminal treatment of a selected site in a body of a patient in which the transfer device has an integral pump (66) for pressurizing, for circulating fluid through a fluid path defined by the transfer device and associated catheter. A removable fluid cartridge (50) is provided including a reservoir (52) from which fluid is drawn by the pump (66) and into which fluid is returned after being circulated through the fluid path. The pump (66) may be a peristaltic pump (66) and the fluid cartridge (50) may include an elongated fluid pick-up having an inlet through which fluid is introduced into the transfer device. The fluid pick-up is sized in length so that the inlet is always submerged in the fluid regardless of the orientation of the transfer device. A removable treatment cartridge (70) having a lumen forming part of the fluid path may also be provided, and a storage sleeve for the treatment cartridge (70) may be of a radiation-blocking material, such as quartz.

35. 发明公开

EP0927060A1 INTRALUMINAL RADIATION TREATMENT SYSTEM 失效
标题翻译：腔内RAYS处理系统
公开(公告)号：EP0927060A1
公开(公告)日：1999-07-07
申请号：EP97945233.0
申请日：1997-09-23
申请人： NOVOSTE CORPORATION
发明人： MELOUL, Raphael, F. , HILLSTEAD, Richard, A. , BONNOIT, George, K., Jr. , TOBIAS, Martin, B.
IPC分类号： A61M25 , A61M1 , A61M36 , A61N5
CPC分类号： A61N5/1002 , A61N5/1007 , A61N2005/1008
摘要： This invention is a tranfer device (12) and catheter assembly (14, 16) for the delivery of treatment elements (unnumbered) to a selected location within the intraluminal passageways of a patient as part of an intraluminal radiation system. The transfer device (12) includes a gate member (98) that permits the treatment elements to leave the transfer device (12) only if the catheter (14) is attached thereto. A pressure indicator (314) provides a visual indication of the fluid pressure within the transfer device, and provides for a release of the fluid if the pressure exceeds a predetermined pressure. The catheter (14) also includes detent (350) to secure it to the transfer device (12), and which must be manually activated to remove the catheter (14) from the transfer device (12).

36. 发明公开

EP0790844A1 VASCULAR SYSTEM TREATING METHOD AND APPARATUS 失效
标题翻译： DEVICE FOR血管的治疗
公开(公告)号：EP0790844A1
公开(公告)日：1997-08-27
申请号：EP95937621.0
申请日：1995-10-23
申请人： NOVOSTE CORPORATION
发明人： WAKSMAN, Ron , WELDON, Thomas, D. , HILLSTEAD, Richard, A. , ROSEN, Jonathan, J. , LARSON, Charles, E. , CROCKER, Ian, R. , MELOUL, Raphael, F.
IPC分类号： A61B , A61M , A61N , A61M36 , A61F2 , A61M3 , A61M25 , A61M29 , A61M31 , A61N5 , G21F5
CPC分类号： A61M25/1002 , A61M25/0028 , A61M25/003 , A61M25/0032 , A61M25/1006 , A61M2025/0034 , A61N5/1002 , A61N5/1007
摘要： This invention is an apparatus and method for delivering a treating element (22), such as a radiation source, through a catheter (60) to a desired site in a vascular system of a patient, such as a coronary artery, for inhibiting the formation of scar tissue such as may occur in restenosis following balloon angioplasty. The apparatus includes an elongate flexible catheter tube (20) having proximal and distal portions, with a lumen (202) extending therebetween, and a diameter sufficiently small for insertion into the patient's vascular system. One or more treating elements (22), such as a capsule or pellet containing radioactive material, is positionable within the lumen and movable between the proximal and distal end portions under the force of a liquid flowing through the lumen. A method for using such apparatus, including a method for using such apparatus simultaneously with a balloon angioplasty procedure, is disclosed.

37. 发明公开

EP0783265A1 APPARATUS AND METHOD FOR PROCEDURES RELATED TO THE ELECTROPHYSIOLOGY OF THE HEART 失效
标题翻译：设备和方法治疗心脏电生理学的
公开(公告)号：EP0783265A1
公开(公告)日：1997-07-16
申请号：EP95929451.0
申请日：1995-08-18
申请人： NOVOSTE CORPORATION
发明人： LARSEN, Charles, E. , TRIP, Roel , JOHNSON, Cheryl, R.
IPC分类号： A61B5 , A61B18 , H01L35 , A61B17
CPC分类号： A61B18/02 , A61B5/0422 , A61B18/1492 , A61B2017/00243 , A61B2018/00047 , A61B2018/0212 , A61B2018/0237 , H01L35/00
摘要： Methods and apparatus are disclosed for use in procedures related to the electrophysiology of the heart, such as identifying or evaluating the electrical activity of the heart, diagnosing and/or treating conditions associated with the electrophysiology of the heart. An apparatus having thermocouple elements (48, 50) of different electromotive potential conductively connected at a junction (56) is introduced into the interior of the heart and a section of heart tissue is contacted with the junction (56). An electrical current is passed through the thermocouple elements (48, 50) to reduce the temperature of the junction (56) in accordance with the Peltier effect and thereby cool the contacted heart tissue. The effect of the cooling may be monitored and, if desired, the section of heart tissue may be treated.

38. 发明公开

EP1659989A1 BALLOON CATHETER WITH NON-DEPLOYABLE STENT 有权转让
标题翻译：球囊导管内支架NICHTABLEGBAREM
公开(公告)号：EP1659989A1
公开(公告)日：2006-05-31
申请号：EP04782334.9
申请日：2004-08-26
申请人： NOVOSTE CORPORATION
发明人： FARNAN, Robert, C. , Hoyns, Dirk Voland , Ram, Anand
IPC分类号： A61F2/06 , A61M29/00 , A61B17/22
CPC分类号： A61M25/104 , A61B17/320725 , A61B2017/00858 , A61B2017/22061 , A61F2/91 , A61F2/915 , A61F2/958 , A61F2002/91525 , A61F2002/91533 , A61F2002/91558 , A61F2210/0076 , A61F2230/005 , A61F2230/0058 , A61F2230/0067 , A61M25/10 , A61M25/1027 , A61M2025/105 , A61M2025/1081 , A61M2025/1086 , A61M2025/1088 , A61M2025/109
摘要： An angioplasty balloon (1) including a non-deployable stent (2 or 102) to prevent or reduce the potential for slippage of the inflated balloon with respect to the vessel wall being treated. The non-deployable stent (102) has a proximal end (103), a distal end (104), and at least one extension section (112), at least one set of serpentine rings (114) and at least one set of elongation links (116) that allow expansion of the strut to accommodate the inflation of the balloon. The stent is made of a material so that the stent collapses upon deflation of the balloon (1).

39. 发明授权

EP0658358B1 Fluid access and flow control valve 失效
标题翻译：访问 - 和流量控制阀
公开(公告)号：EP0658358B1
公开(公告)日：2004-03-03
申请号：EP94118148.9
申请日：1994-11-17
申请人： NOVOSTE CORPORATION
发明人： Weldon, Thomas D. , Larsen, Charles E. , Rosen, Jonathan J.
IPC分类号： A61M39/26 , A61M5/168 , F16K7/02
CPC分类号： F16K7/02 , A61M5/16877 , A61M39/26

40. 发明公开

EP1208869A3 Wound treating device 失效
标题翻译：用于治疗创伤的装置
公开(公告)号：EP1208869A3
公开(公告)日：2003-05-07
申请号：EP02002705.8
申请日：1994-06-08
申请人： NOVOSTE CORPORATION
发明人： Weldon, Thomas D. , Larsen, Charles E. , Rosen, Johnathan J.
IPC分类号： A61M25/01 , A61B17/00
CPC分类号： A61M25/0119 , A61B17/0057 , A61F2/06 , A61F2013/00357 , A61F2013/00472 , A61M25/10 , A61M2025/1015
摘要： The present invention relates to a wound treating device having a tubular portion (28) with proximal and distal ends (30 and 32) and at least one lumen (34) extending therebetween. An inflatable means is located at the distal end (32) of the tubular portion (28), and is made up of a flexible membrane (36). The inflatable means is positionable within the distal end (32) of the tubular portion (28) and is movable between a retracted position within the tubular portion and an inflated position to form a balloon-like projection which may be placed adjacent an aperture in a blood vessel to aid in slowing or stopping blood flow from the aperture. In another embodiment of this invention, the elongated tube (28 or 72) of the wound treating device has proximal and distal end portions (30 or 76 and 32 or 74) and at least two lumens extending between the proximal and distal ends. The first lumen (68) is adapted to receive a flow control device (60) so that the flow control device (60) may be partially positioned within the blood vessel for providing local flow control at the aperture in the blood vessel. The flow control device (60) has a tubular portion (62) with an inflatable membrane (66) attached at its distal end which defines a balloon-like portion when inflated. The balloon-like portion is adapted to control the flow of fluid through the aperture. An inflatable means is attached to the second lumen of the wound treating device's tubular portion. The inflatable means has a flexible membrane (36 or 84) carried generally adjacent its distal end portion (32 or 74) and is movable between a retracted position and an inflated position to form a balloon-like projection at the distal end of the wound treating device.

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