专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

31. 发明授权

US08247404B2 Derivatives of 2-oxoalkyl-1-piperazin-2-one, preparation method thereof and therapeutic use of same 有权
标题翻译： 2-氧代烷基-1-哌嗪-2-酮的衍生物及其制备方法及其治疗用途
公开(公告)号：US08247404B2
公开(公告)日：2012-08-21
申请号：US12966408
申请日：2010-12-13
申请人： Marco Baroni , Francoise Bono , Sandrine Delbary-Gossart
发明人： Marco Baroni , Francoise Bono , Sandrine Delbary-Gossart
IPC分类号： A61K31/497 , A61K31/55 , A01N43/00 , C07D401/00 , C07D213/44 , C07D295/00
CPC分类号： C07D401/14
摘要： The present invention relates to derivatives of 4-{2-[phenyl-3,6-dihydropyridin-1-yl]-2-oxoalkyl}-1-piperazin-2-one and 4-{2-[phenyl-2,5-dihydropyrrol-1-yl]-2-oxoalkyl}-1-piperazin-2-one having general formula (I): in which A, B, m, R3 and n are as defined herein. The invention also relates to the preparation thereof and to the therapeutic use thereof.
摘要翻译：本发明涉及4- {2- [苯基-3,6-二氢吡啶-1-基] -2-氧代烷基} -1-哌嗪-2-酮和4- {2- [苯基-2,5 - 二氢吡咯-1-基] -2-氧代烷基} -1-哌嗪-2-酮，其中A，B，m，R 3和n如本文所定义。本发明还涉及其制备及其治疗用途。

32. 发明授权

US07186720B2 Tetrahydropyridyl-alkyl-heterocycles, method for preparing the same and pharmaceutical compositions containing the same 失效
标题翻译：四氢吡啶基 - 烷基 - 杂环，其制备方法和含有它们的药物组合物
公开(公告)号：US07186720B2
公开(公告)日：2007-03-06
申请号：US10475460
申请日：2002-04-19
申请人： Marco Baroni , Bernard Bourrie , Pierre Casellas
发明人： Marco Baroni , Bernard Bourrie , Pierre Casellas
IPC分类号： A61K31/498 , A61K31/502 , A61K31/4709 , A61K31/4439 , C07D401/06 , C07D401/14
CPC分类号： C07D401/06 , C07D401/14
摘要： The present invention relates to compounds of formula (I): in which X represents N or CH; R1 represents a hydrogen or halogen atom or a CF3 group; R2 and R3 independently represent a hydrogen atom or a methyl group; n is 0 or 1; A represents an optionally substituted nitrogenous heterocycle; and to their N-oxides and to their salts or solvates, to the pharmaceutical compositions and the medicaments comprising them, and to a process for their preparation.
摘要翻译：本发明涉及式（I）化合物：其中X表示N或CH; R 1表示氢或卤素原子或CF 3 N 3基团; R 2和R 3独立地表示氢原子或甲基; n为0或1; A表示任选取代的含氮杂环; 以及它们的N-氧化物及其盐或溶剂化物，涉及药物组合物和包含它们的药物及其制备方法。

33. 发明授权

US07151107B2 Use of benzoylalkyl-1,2,3,6-tetrahydropyridines 失效
公开(公告)号：US07151107B2
公开(公告)日：2006-12-19
申请号：US11135998
申请日：2005-05-24
申请人： Marco Baroni , Rosanna Cardamone , Jacqueline Fournier , Umberto Guzzi , Alessandra Ielmini
发明人： Marco Baroni , Rosanna Cardamone , Jacqueline Fournier , Umberto Guzzi , Alessandra Ielmini
IPC分类号： A61K31/4418 , C07D211/68
CPC分类号： C07D211/70 , A61K31/4418
摘要： The invention relates to the use of compounds of formula for the preparation of medicines designed for the treatment of neuronal and cerebral disorders. The invention also relates to the compounds of formula: a process for their preparation and the pharmaceutical compositions containing them.

34. 发明申请

US20050209216A1 Phenyl-and pyridyl-diazaheterocycles having a tnf-modulating activity 审中-公开
标题翻译：具有tnf调节活性的苯基和吡啶基 - 二氮杂环
公开(公告)号：US20050209216A1
公开(公告)日：2005-09-22
申请号：US10518652
申请日：2003-06-16
申请人： Marco Baroni , Bernard Bourrie , Pierre Casellas
发明人： Marco Baroni , Bernard Bourrie , Pierre Casellas
IPC分类号： A61K31/497 , A61K31/55 , A61K31/551 , A61P1/04 , A61P9/00 , A61P9/10 , A61P11/00 , A61P11/06 , A61P13/12 , A61P17/00 , A61P19/02 , A61P19/06 , A61P19/08 , A61P19/10 , A61P25/04 , A61P25/16 , A61P25/28 , A61P29/00 , A61P31/00 , A61P31/04 , A61P31/06 , A61P31/10 , A61P31/12 , A61P33/06 , A61P35/00 , A61P37/00 , A61P37/04 , A61P43/00 , C07D215/04 , C07D217/02 , C07D241/08 , C07D401/06 , C07D401/12 , C07D401/14 , C07D487/04 , A61K31/495 , A61K31/496 , C07D43/02
CPC分类号： C07D215/04 , C07D217/02 , C07D241/08 , C07D401/06 , C07D401/14
摘要： The present invention relates to compounds of formula (I): in which X represents N or CH; R1 represents a hydrogen or halogen atom or a CF3 group; W represents a diazoheterocycle; R2 and R3 independently represent a hydrogen atom or a methyl group; n is 0 or 1; A represents a quinoline or an isoquinoline which are optionally substituted.
摘要翻译：本发明涉及式（I）化合物：其中X表示N或CH; R 1表示氢或卤素原子或CF 3 N 3基团; W代表重氮杂环; R 2和R 3独立地表示氢原子或甲基; n为0或1; A代表任选取代的喹啉或异喹啉。

35. 发明授权

US06936621B2 Use of benzoylalkyl-1,2,3,6-tetrahydropyridines 失效
公开(公告)号：US06936621B2
公开(公告)日：2005-08-30
申请号：US10729313
申请日：2003-12-05
申请人： Marco Baroni , Rosanna Cardamone , Jacqueline Fournier , Umberto Guzzi , Alessandra Ielmini
发明人： Marco Baroni , Rosanna Cardamone , Jacqueline Fournier , Umberto Guzzi , Alessandra Ielmini
IPC分类号： A61K31/44 , A61K31/4409 , A61K31/4418 , A61P25/00 , A61P43/00 , C07D211/70 , A61K31/435 , C07D211/68
CPC分类号： C07D211/70 , A61K31/4418
摘要： The invention relates to the use of compounds of formula for the preparation of medicines designed for the treatment of neuronal and cerebral disorders. The invention also relates to the compounds of formula: a process for their preparation and the pharmaceutical compositions containing them.

36. 发明申请

US20050014795A1 Aralkyl-tetrahydro-pyridines, their preparation and pharmaceutical compositions containing same 失效
标题翻译：芳烷基 - 四氢 - 吡啶，其制备方法和含有它们的药物组合物
公开(公告)号：US20050014795A1
公开(公告)日：2005-01-20
申请号：US10492770
申请日：2002-10-14
申请人： Marco Baroni , Bernard Bourrie , Rosanna Cardamone , Pierre Casellas
发明人： Marco Baroni , Bernard Bourrie , Rosanna Cardamone , Pierre Casellas
IPC分类号： A61K20060101 , A61K31/4409 , A61K31/4418 , A61K31/444 , A61P20060101 , A61P1/04 , A61P1/10 , A61P9/10 , A61P11/06 , A61P13/12 , A61P17/00 , A61P17/06 , A61P19/02 , A61P19/06 , A61P19/08 , A61P25/00 , A61P25/16 , A61P25/28 , A61P27/02 , A61P29/00 , A61P31/02 , A61P31/04 , A61P31/06 , A61P31/08 , A61P35/00 , A61P37/00 , A61P37/06 , A61P37/08 , C07C57/50 , C07D20060101 , C07D211/70 , C07D211/72 , C07D211/80 , C07D401/04 , C07
CPC分类号： C07D401/04 , C07D211/70
摘要： The present invention relates to compounds of formula (I): in which X represents N or CH; R1 represents a hydrogen or halogen atom or a CF3 group; n is an integer from 1 to 5; A represents a partially saturated carbonaceous bi- or tricycle; it also relates to their salts, solvates, N-oxides, the pharmaceutical compositions containing them, a method for their preparation and synthesis intermediates in this method.
摘要翻译：本发明涉及式（I）化合物：其中X表示N或CH; R1表示氢或卤素原子或CF3基团; n为1〜5的整数; A表示部分饱和的碳质二元或三轮车; 它还涉及它们的盐，溶剂合物，N-氧化物，含有它们的药物组合物，其制备方法和该方法中的合成中间体。

37. 发明授权

US5488151A {(7S)-7-[(2R )-2-(3-chlorophenyl)-2-hydroxyethylamino)-2-hydroxyethylamino]5,} acetic acid and its pharmaceutically acceptable salts 失效
标题翻译： {（7S）-7 - [（2R）-2-（3-氯苯基）-2-羟乙基氨基）-2-羟乙基氨基] 5,6,7,8-四氢萘-2-基氧基}乙酸及其药学上可接受的盐
公开(公告)号：US5488151A
公开(公告)日：1996-01-30
申请号：US250830
申请日：1994-05-31
申请人： Marco Baroni , Roberto Cecchi , Tiziano Croci
发明人： Marco Baroni , Roberto Cecchi , Tiziano Croci
IPC分类号： A61K31/19 , A61P1/04 , A61P3/04 , A61P25/24 , A61P25/26 , A61P27/02 , C07C217/54 , C07C217/62 , C07C217/74 , C07C229/40
CPC分类号： C07C217/54 , C07C217/62 , C07C2102/10
摘要： The present invention relates to the novel compound {(7S)-7-[(2R)-2-(3-chlorophenyl)-2-hydroxyethylamino]-5,6,7,8-tetrahydronaphthalen-2-yloxy}acetic acid of formula (I): ##STR1## and its pharmaceutically acceptable salts, which act as .beta..sub.3 -adrenergic agonists, and to the pharmaceutical compositions and laboratory reagents in which it is present.
摘要翻译：本发明涉及新的化合物{（7S）-7 - [（2R）-2-（3-氯苯基）-2-羟乙基氨基] -5,6,7,8-四氢萘-2-基氧基}乙酸式（I）：其作为β3-肾上腺素能激动剂的药学上可接受的盐及其存在于其中的药物组合物和实验室试剂。

38. 发明申请

WO2009130657A1 A ROTARY CONVEYOR COMPRISING A GRIPPΞR MECHANISM 审中-公开
标题翻译：包括GRIPP？R机械的旋转输送机
公开(公告)号：WO2009130657A1
公开(公告)日：2009-10-29
申请号：PCT/IB2009/051619
申请日：2009-04-20
申请人： AZIONARIA COSTRUZIONI MACCHINE AUTOMATICHE A.C.M.A. S.P.A. , MARCO, Baroni , GIANPIETRO, Zanini
发明人： MARCO, Baroni , GIANPIETRO, Zanini
IPC分类号： B67B3/20
CPC分类号： B67B3/2033 , B67B3/206
摘要： The components of a rotary conveyor (1) for a carousel type capping machine (2) include a centre shaft aligned on a main axis (X) coinciding with the main axis of the machine (2), a carrier element (4) coupled to the shaft so that the two rotate as one about the main axis (X), and a set of gripper mechanisms (5) associated operationally with the carrier element (4), distributed circumferentially about the supporting shaft. Each gripper mechanism (5) is switchable between a first configuration, establishing a recess (6) in which to accommodate a respective container (3), a second configuration in which the container (3) is retained within the recess (6) by a predetermined gripping force, and a third configuration in which the container (3) is restrained by a gripping force greater than the force exerted in the second configuration, so as to counteract any unwanted rotation of the container (3) about its longitudinal axis (Y) that might be induced during the course of capping operations.
摘要翻译：用于圆盘传送带式封盖机（2）的旋转输送机（1）的部件包括：与主机轴线（X）对准的中心轴，该主轴线（X）与机器（2）的主轴线重合，载体元件（4）所述轴使得所述两个围绕所述主轴线（X）旋转，并且与所述载体元件（4）可操作地相关联的一组夹持器机构（5）围绕所述支撑轴周向分布。每个夹持器机构（5）可在第一构型之间切换，建立容纳相应容器（3）的凹部（6），其中容器（3）通过凹部（6）保持在凹部（6）内的第二构型以及第三构造，其中通过大于在第二构造中施加的力的夹持力约束容器（3），以抵抗容器（3）围绕其纵向轴线（Y）的任何不期望的旋转），这可能是在封顶作业过程中引起的。

39. 发明授权

US08458992B2 Capping machine 有权
标题翻译：封盖机
公开(公告)号：US08458992B2
公开(公告)日：2013-06-11
申请号：US12671156
申请日：2008-07-30
申请人： Gianpietro Zanini , Marco Baroni
发明人： Gianpietro Zanini , Marco Baroni
IPC分类号： B67B3/20
CPC分类号： B67B3/22 , B67B3/2033
摘要： Containers are closed with screw caps by a carousel machine of which a central drum (31) is rotatable about a vertical axis (A) and carries a set of capping units (36) equipped with respective capping heads (37), each presenting a gripper (38) by which the cap (3) is held, and a mechanism (66) by which the hinged jaws (39) of the gripper (38) are opened and closed; each capping head (37) is capable of axial motion induced by components incorporated into the relative unit (36), which are guided axially in their movements and supported by auxiliary components (40; 49, 50) associated rigidly with the central drum (31).
摘要翻译：容器用圆盘传送带封闭，中心鼓（31）围绕垂直轴线（A）旋转，并传送一套装有各自的封盖头（37）的封盖单元（36）（38），其中保持盖（3），以及机构（66），夹持器（38）的铰接爪（39）通过该机构打开和关闭; 每个封盖头（37）能够由结合到所述相关单元（36）中的部件引起的轴向运动，所述部件在其运动中被轴向引导并由与中心鼓（31）刚性关联的辅助部件（40; 49,50）支撑）。

40. 发明授权

US08375682B2 Gripping apparatus for capping assemblies in container packaging machines 失效
标题翻译：用于容器包装机中封盖组件的夹持装置
公开(公告)号：US08375682B2
公开(公告)日：2013-02-19
申请号：US12671136
申请日：2008-07-30
申请人： Gianpietro Zanini , Marco Baroni
发明人： Gianpietro Zanini , Marco Baroni
IPC分类号： B67B3/20
CPC分类号： B65B7/2835 , B65B59/04 , B67B3/2066 , B67B2201/10
摘要： Capping assemblies (2) of the type fitted to capping units (1a) in a machine for packaging containers filled with fluid or powdered products are equipped with a gripping apparatus (1) comprising a gripper (4) with three arms (5), each carrying an adapter (20) furnished with a pad (20b) offered in direct contact to the cap, through which the gripping action is applied. Each adapter (20) is secured to a fitting (17, 18) insertable into a socket (16) afforded by the bottom of a structural member (6) that forms the main part of each arm (5) and is hinged to the movable head of a relative capping assembly (2); when inserted into the structural member (6), the fitting (17, 18) is retained automatically by a snap lock mechanism (12) incorporated into the arm (5), which can be released subsequently by introducing the tip of a screwdriver into a slot (18a) created in the side of the fitting (17, 18) and levering the components apart.
摘要翻译：在装有流体或粉末产品的容器的包装容器的机器中安装有封盖装置（1a）的类型的封盖组件（2）装备有夹持装置（1），其包括具有三个臂（5）的夹持器（5）携带适配器（20），所述适配器（20）配备有直接接触盖的提供的垫（20b），通过该适配器施加夹紧动作。每个适配器（20）被固定到可插入由形成每个臂（5）的主要部分的结构构件（6）的底部提供的插座（16）中的配件（17,18），并且铰接到可移动的相对封盖组件（2）的头部; 当插入到结构构件（6）中时，配件（17,18）由结合到臂（5）中的卡扣锁定机构（12）自动保持，随后可以通过将螺丝刀的尖端引入到臂在所述配件（17,18）的侧面中形成并且将所述部件分开的槽（18a）。

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式